Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1p36.22 52 (14%) 317 9.9999e-06 0.0081 0.0229 1 0.5179 1 0.24175 1 0.00021 0.111 0.11933 1 0.11014 1 0.04255 1 0.11932 1 0.03007 1 amp_1q21.3 135 (37%) 234 9.9999e-06 0.0081 9.9999e-06 0.0081 0.03303 1 0.02697 1 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 amp_1q42.3 122 (33%) 247 9.9999e-06 0.0081 9.9999e-06 0.0081 0.40238 1 0.096509 1 9.9999e-06 0.0081 8.9999e-05 0.0498 9.9999e-06 0.0081 9.9999e-06 0.0081 0.00446 1 9.9999e-06 0.0081 amp_3q26.2 125 (34%) 244 9.9999e-06 0.0081 0.00256 1 0.821 1 0.01119 1 0.44844 1 0.02867 1 0.01408 1 0.01766 1 0.0195 1 0.00437 1 amp_5p15.33 104 (28%) 265 9.9999e-06 0.0081 9.9999e-06 0.0081 0.12646 1 0.98509 1 9.9999e-06 0.0081 5e-05 0.0288 9.9999e-06 0.0081 2e-05 0.0124 9.9999e-05 0.055 9.9999e-06 0.0081 amp_5p13.1 103 (28%) 266 9.9999e-06 0.0081 9.9999e-06 0.0081 0.73993 1 0.85987 1 9.9999e-06 0.0081 5e-04 0.241 0.00018 0.0965 0.00011 0.0604 0.00117 0.516 9.9999e-06 0.0081 amp_6p21.1 99 (27%) 270 9.9999e-06 0.0081 9.9999e-06 0.0081 0.34845 1 0.1646 1 0.00064999 0.304 0.00076999 0.356 0.00033 0.167 0.00029 0.148 0.00034 0.17 2e-05 0.0124 amp_6q12 73 (20%) 296 9.9999e-06 0.0081 9.9999e-06 0.0081 0.066949 1 0.88324 1 6.9999e-05 0.0393 0.00037 0.184 0.00104 0.468 0.00032 0.163 0.00061999 0.291 3e-05 0.0179 amp_6q21 68 (18%) 301 9.9999e-06 0.0081 0.00054999 0.262 0.38263 1 0.4056 1 0.00143 0.613 0.00151 0.645 0.00125 0.542 0.00050999 0.245 0.00225 0.9 9.9999e-06 0.0081 amp_7p22.1 189 (51%) 180 9.9999e-06 0.0081 5e-05 0.0288 0.63572 1 0.86442 1 0.00021 0.111 3e-05 0.0179 0.00213 0.861 0.00050999 0.245 0.00172 0.724 9.9999e-06 0.0081 amp_7p11.2 172 (47%) 197 9.9999e-06 0.0081 0.00117 0.516 0.90553 1 0.85129 1 0.04374 1 0.00050999 0.245 0.0094899 1 0.04078 1 0.00199 0.818 0.00123 0.536 amp_7q21.2 168 (46%) 201 9.9999e-06 0.0081 0.00062999 0.295 0.19862 1 0.67052 1 0.51605 1 6.9999e-05 0.0393 0.02186 1 0.058149 1 0.04931 1 0.00255 1 amp_8p23.1 146 (40%) 223 5.9999e-05 0.0341 7.9999e-05 0.0446 0.59062 1 0.6021 1 0.054809 1 0.01783 1 0.36374 1 0.34441 1 0.03713 1 0.055039 1 amp_8q24.21 256 (69%) 113 9.9999e-06 0.0081 0.00033 0.167 0.38486 1 0.3824 1 0.0057999 1 0.01079 1 7.9999e-05 0.0446 0.00029 0.148 9.9999e-06 0.0081 9.9999e-06 0.0081 amp_9p24.1 57 (15%) 312 2e-05 0.0124 0.44928 1 0.61709 1 0.21899 1 0.10944 1 0.0055699 1 0.03109 1 0.30818 1 0.03804 1 0.12854 1 amp_9p13.3 71 (19%) 298 0.00274 1 0.48349 1 0.26666 1 0.31561 1 0.0098299 1 0.23203 1 0.0073199 1 0.43372 1 0.00179 0.745 0.17068 1 amp_9q34.3 98 (27%) 271 0.00025 0.129 0.17935 1 0.71166 1 0.56038 1 0.0286 1 0.29656 1 0.02872 1 0.42904 1 0.1666 1 0.093959 1 amp_10p11.22 98 (27%) 271 9.9999e-06 0.0081 9.9999e-06 0.0081 0.14722 1 0.52256 1 0.00112 0.5 0.0092699 1 0.00343 1 0.00013 0.0706 0.00184 0.762 8.9999e-05 0.0498 amp_10q22.2 68 (18%) 301 9.9999e-06 0.0081 0.0201 1 0.02687 1 0.25171 1 0.01821 1 0.02298 1 0.20223 1 0.18447 1 0.097599 1 0.02358 1 amp_10q26.13 72 (20%) 297 9.9999e-06 0.0081 0.0022 0.882 0.03627 1 0.33002 1 0.0055599 1 0.03177 1 0.63329 1 0.11046 1 0.89926 1 0.082699 1 amp_11p13 70 (19%) 299 0.00052999 0.253 0.04096 1 0.64347 1 0.11617 1 0.00056999 0.27 0.0058999 1 0.059579 1 0.00017 0.0915 0.064159 1 0.00456 1 amp_11q13.3 90 (24%) 279 9.9999e-06 0.0081 0.01811 1 0.18966 1 0.63905 1 0.12717 1 0.03702 1 0.00032 0.163 0.0061899 1 0.00017 0.0915 0.00172 0.724 amp_12p12.1 109 (30%) 260 9.9999e-06 0.0081 0.03774 1 0.42823 1 0.34777 1 0.20852 1 0.3667 1 0.00308 1 0.22987 1 0.00437 1 0.051079 1 amp_12q15 92 (25%) 277 9.9999e-06 0.0081 0.36114 1 0.21975 1 0.32889 1 0.27551 1 0.075209 1 0.089489 1 0.38898 1 0.25428 1 0.71569 1 amp_13q12.3 144 (39%) 225 9.9999e-06 0.0081 9.9999e-06 0.0081 0.32972 1 0.15262 1 0.01649 1 3e-05 0.0179 0.00033 0.167 0.00461 1 4e-04 0.198 0.00027 0.139 amp_13q22.1 149 (40%) 220 9.9999e-06 0.0081 9.9999e-06 0.0081 0.20035 1 0.67934 1 2e-05 0.0124 9.9999e-06 0.0081 0.00044 0.215 2e-05 0.0124 9.9999e-06 0.0081 9.9999e-06 0.0081 amp_15q26.1 88 (24%) 281 9.9999e-06 0.0081 0.00024 0.125 0.46411 1 0.28843 1 9.9999e-06 0.0081 2e-05 0.0124 0.0079699 1 0.0095299 1 0.0057699 1 0.00305 1 amp_17q12 116 (31%) 253 9.9999e-06 0.0081 9.9999e-06 0.0081 0.79457 1 0.03977 1 0.00021 0.111 0.00019 0.101 4e-05 0.0234 0.00021 0.111 0.0018 0.747 0.00091999 0.42 amp_18q11.2 117 (32%) 252 9.9999e-06 0.0081 0.00216 0.87 0.29368 1 0.28602 1 0.01519 1 0.00386 1 0.00126 0.546 0.00208 0.847 0.00092999 0.422 0.0049 1 amp_19p13.2 41 (11%) 328 0.00033 0.167 0.1187 1 0.90523 1 0.7566 1 0.73263 1 0.16045 1 0.9774 1 0.9756 1 0.87543 1 0.74388 1 amp_19q12 111 (30%) 258 9.9999e-06 0.0081 9.9999e-06 0.0081 0.0061799 1 0.11469 1 9.9999e-06 0.0081 9.9999e-06 0.0081 2e-05 0.0124 9.9999e-06 0.0081 0.00374 1 9.9999e-06 0.0081 amp_20q13.2 243 (66%) 126 9.9999e-06 0.0081 9.9999e-06 0.0081 0.0063699 1 0.01191 1 9.9999e-06 0.0081 9.9999e-06 0.0081 2e-05 0.0124 9.9999e-06 0.0081 0.00378 1 9.9999e-06 0.0081 amp_xq27.3 67 (18%) 302 6.9999e-05 0.0393 0.00324 1 0.59836 1 0.9633 1 0.18668 1 9.9999e-06 0.0081 0.02973 1 0.96944 1 0.054359 1 0.072319 1 del_1p36.11 104 (28%) 265 9.9999e-06 0.0081 9.9999e-06 0.0081 0.15634 1 0.00094999 0.43 0.00033 0.167 9.9999e-06 0.0081 0.0096199 1 0.00011 0.0604 0.00218 0.876 9.9999e-06 0.0081 del_1p13.2 75 (20%) 294 9.9999e-06 0.0081 9.9999e-06 0.0081 0.080619 1 0.063569 1 0.00122 0.533 0.00090999 0.416 0.18192 1 0.01702 1 0.01942 1 0.00317 1 del_1q25.1 13 (4%) 356 0.03729 1 0.094419 1 0.16792 1 0.89525 1 0.44398 1 0.41494 1 0.20678 1 0.71032 1 0.18816 1 0.071819 1 del_1q44 23 (6%) 346 0.00313 1 0.00103 0.465 0.30908 1 0.37279 1 0.73945 1 0.33748 1 0.01453 1 0.44327 1 0.01062 1 0.15525 1 del_2q32.1 53 (14%) 316 0.0088999 1 0.098849 1 0.49031 1 0.082589 1 0.090419 1 0.23992 1 0.37712 1 0.00206 0.84 0.15261 1 0.14674 1 del_2q37.2 54 (15%) 315 9.9999e-06 0.0081 5e-05 0.0288 0.27326 1 0.34505 1 0.00333 1 0.21376 1 0.0225 1 9.9999e-06 0.0081 0.080049 1 0.00167 0.706 del_3p26.1 115 (31%) 254 9.9999e-06 0.0081 2e-05 0.0124 0.34258 1 0.19442 1 0.0066299 1 5e-05 0.0288 8.9999e-05 0.0498 4e-05 0.0234 0.00043 0.212 9.9999e-06 0.0081 del_3p14.2 131 (36%) 238 9.9999e-06 0.0081 9.9999e-06 0.0081 0.40898 1 0.3713 1 7.9999e-05 0.0446 0.00019 0.101 9.9999e-06 0.0081 9.9999e-06 0.0081 0.00042 0.207 9.9999e-06 0.0081 del_3q26.31 46 (12%) 323 9.9999e-06 0.0081 9.9999e-06 0.0081 0.13357 1 0.37313 1 0.00043 0.212 0.00046 0.224 0.00123 0.536 0.00055999 0.265 0.00178 0.742 0.00282 1 del_4p16.3 142 (38%) 227 9.9999e-06 0.0081 0.00051999 0.249 0.45959 1 0.20071 1 3e-05 0.0179 5e-05 0.0288 0.00046 0.224 9.9999e-06 0.0081 0.00015 0.0811 9.9999e-06 0.0081 del_4q22.1 160 (43%) 209 9.9999e-06 0.0081 5.9999e-05 0.0341 0.10768 1 0.26818 1 0.00253 0.999 3e-05 0.0179 0.02907 1 0.00203 0.832 0.03044 1 0.00047 0.227 del_4q34.3 163 (44%) 206 9.9999e-06 0.0081 9.9999e-06 0.0081 0.051929 1 0.0088699 1 9.9999e-06 0.0081 2e-05 0.0124 4e-05 0.0234 9.9999e-06 0.0081 2e-05 0.0124 2e-05 0.0124 del_5q11.2 134 (36%) 235 9.9999e-06 0.0081 9.9999e-06 0.0081 0.24002 1 0.22377 1 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 del_5q23.2 122 (33%) 247 9.9999e-06 0.0081 9.9999e-06 0.0081 0.12288 1 0.10897 1 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 del_6p25.3 93 (25%) 276 9.9999e-06 0.0081 2e-04 0.106 0.13825 1 0.82083 1 0.00011 0.0604 5.9999e-05 0.0341 0.00068999 0.322 2e-05 0.0124 0.0072899 1 0.00043 0.212 del_6q14.1 72 (20%) 297 9.9999e-06 0.0081 0.00111 0.497 0.21388 1 0.8437 1 0.00060999 0.287 0.0050499 1 0.1233 1 0.0164 1 0.072169 1 0.04809 1 del_6q26 82 (22%) 287 9.9999e-06 0.0081 0.0082399 1 0.79159 1 0.70177 1 0.00077999 0.36 0.00247 0.978 0.15885 1 0.01163 1 0.077459 1 0.0063999 1 del_7q31.1 54 (15%) 315 9.9999e-06 0.0081 4e-05 0.0234 0.71467 1 0.49754 1 0.0085199 1 0.27684 1 0.01958 1 0.0070699 1 0.00376 1 0.00427 1 del_7q36.3 78 (21%) 291 9.9999e-06 0.0081 2e-05 0.0124 0.37977 1 0.079209 1 2e-05 0.0124 0.00034 0.17 0.00021 0.111 9.9999e-06 0.0081 0.00198 0.816 2e-05 0.0124 del_8p23.3 102 (28%) 267 9.9999e-06 0.0081 9.9999e-06 0.0081 0.075559 1 0.59437 1 9.9999e-06 0.0081 9.9999e-06 0.0081 0.00111 0.497 9.9999e-06 0.0081 5.9999e-05 0.0341 9.9999e-06 0.0081 del_9p23 156 (42%) 213 9.9999e-06 0.0081 2e-05 0.0124 0.02913 1 0.00113 0.502 9.9999e-06 0.0081 0.00176 0.737 0.00159 0.676 0.00356 1 0.03545 1 0.00091999 0.42 del_9p21.3 153 (41%) 216 9.9999e-06 0.0081 9.9999e-06 0.0081 6.9999e-05 0.0393 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 0.00498 1 0.00074999 0.347 0.0067599 1 4e-05 0.0234 del_9q21.11 93 (25%) 276 9.9999e-06 0.0081 0.00346 1 0.13855 1 0.056499 1 0.00155 0.66 0.03544 1 0.00478 1 0.00049 0.237 0.00171 0.722 0.00024 0.125 del_10p15.3 62 (17%) 307 3e-05 0.0179 0.0188 1 0.30425 1 0.41691 1 0.059989 1 0.10174 1 0.060289 1 0.03765 1 0.0086499 1 0.0066399 1 del_10q22.3 61 (17%) 308 9.9999e-06 0.0081 0.0136 1 0.74886 1 0.057659 1 0.00018 0.0965 0.00035 0.174 0.0058399 1 0.0053199 1 0.00332 1 0.00022 0.115 del_10q23.31 90 (24%) 279 9.9999e-06 0.0081 0.00015 0.0811 0.063409 1 0.00019 0.101 9.9999e-06 0.0081 9.9999e-06 0.0081 0.00013 0.0706 5.9999e-05 0.0341 0.00115 0.509 9.9999e-06 0.0081 del_11p15.4 79 (21%) 290 9.9999e-06 0.0081 9.9999e-06 0.0081 2e-05 0.0124 0.00079999 0.368 0.00145 0.621 0.01269 1 0.00108 0.485 7.9999e-05 0.0446 0.03796 1 0.00118 0.517 del_11q23.2 82 (22%) 287 9.9999e-06 0.0081 0.0081799 1 0.70079 1 0.15338 1 0.00112 0.5 0.00012 0.0654 0.091359 1 0.20353 1 0.02786 1 0.04259 1 del_12p13.1 57 (15%) 312 9.9999e-06 0.0081 9.9999e-06 0.0081 0.54096 1 0.4188 1 3e-05 0.0179 3e-05 0.0179 0.01875 1 0.01204 1 0.01142 1 5e-05 0.0288 del_13q12.11 52 (14%) 317 9.9999e-06 0.0081 0.10895 1 0.42605 1 0.36566 1 0.065769 1 0.02223 1 0.39012 1 0.42302 1 0.17854 1 0.2192 1 del_14q23.3 108 (29%) 261 9.9999e-06 0.0081 9.9999e-06 0.0081 0.75152 1 0.43015 1 4e-05 0.0234 0.00043 0.212 0.00129 0.557 3e-05 0.0179 0.00073999 0.344 0.00012 0.0654 del_14q32.33 106 (29%) 263 9.9999e-06 0.0081 0.00069999 0.326 0.92765 1 0.22163 1 0.00209 0.847 0.0052399 1 0.02165 1 0.03193 1 0.02923 1 0.068349 1 del_15q11.2 101 (27%) 268 9.9999e-06 0.0081 3e-05 0.0179 0.00177 0.74 0.26722 1 9.9999e-06 0.0081 2e-05 0.0124 0.00024 0.125 2e-05 0.0124 9.9999e-06 0.0081 9.9999e-06 0.0081 del_15q15.1 103 (28%) 266 9.9999e-06 0.0081 9.9999e-06 0.0081 0.00356 1 0.29414 1 9.9999e-06 0.0081 2e-05 0.0124 0.00117 0.516 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 del_16p13.3 75 (20%) 294 9.9999e-06 0.0081 0.00056999 0.27 0.69999 1 0.81704 1 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 5e-05 0.0288 9.9999e-06 0.0081 9.9999e-06 0.0081 del_16q23.1 146 (40%) 223 9.9999e-06 0.0081 0.00272 1 0.47043 1 0.17038 1 0.00187 0.772 0.0090999 1 0.00442 1 0.0185 1 5e-05 0.0288 0.00096999 0.438 del_17p12 141 (38%) 228 9.9999e-06 0.0081 9.9999e-06 0.0081 0.40051 1 0.0082399 1 9.9999e-06 0.0081 9.9999e-06 0.0081 4e-05 0.0234 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 del_17q24.3 68 (18%) 301 9.9999e-06 0.0081 0.00011 0.0604 0.19043 1 0.22018 1 0.00161 0.683 0.00235 0.935 0.069729 1 0.00041 0.203 0.00363 1 0.00135 0.58 del_18q21.2 169 (46%) 200 9.9999e-06 0.0081 0.00046 0.224 0.66728 1 0.45165 1 0.00031 0.158 0.0041 1 0.00115 0.509 0.00278 1 2e-04 0.106 0.00374 1 del_19p13.3 127 (34%) 242 9.9999e-06 0.0081 9.9999e-06 0.0081 0.00364 1 0.00495 1 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 9.9999e-06 0.0081 del_19q13.11 57 (15%) 312 9.9999e-06 0.0081 9.9999e-06 0.0081 0.063429 1 0.71141 1 2e-05 0.0124 0.00054999 0.262 0.00024 0.125 9.9999e-06 0.0081 0.00027 0.139 5.9999e-05 0.0341 del_20p12.1 31 (8%) 338 0.00208 0.847 0.00233 0.93 0.65835 1 0.19235 1 0.01537 1 0.085479 1 0.0292 1 0.11249 1 0.02619 1 0.066279 1 del_21q11.2 140 (38%) 229 9.9999e-06 0.0081 0.00027 0.139 0.34203 1 0.20249 1 0.0024 0.953 0.00445 1 5.9999e-05 0.0341 0.01126 1 4e-05 0.0234 0.00032 0.163 del_21q22.13 152 (41%) 217 9.9999e-06 0.0081 0.02242 1 0.10155 1 0.23991 1 0.00203 0.832 0.00037 0.184 0.00023 0.12 0.00087999 0.403 4e-05 0.0234 0.00073999 0.344 del_22q13.31 129 (35%) 240 9.9999e-06 0.0081 9.9999e-06 0.0081 0.0486 1 0.0064599 1 0.0013 0.56 0.00435 1 3e-05 0.0179 9.9999e-06 0.0081 0.00085999 0.395 9.9999e-06 0.0081 del_xp22.2 67 (18%) 302 9.9999e-06 0.0081 2e-05 0.0124 0.36699 1 0.058959 1 0.00019 0.101 0.00024 0.125 0.090959 1 0.00298 1 0.21466 1 0.00016 0.0862 del_xp21.1 64 (17%) 305 9.9999e-06 0.0081 0.00338 1 0.092889 1 0.02246 1 0.01406 1 0.0254 1 0.19721 1 0.33617 1 0.21718 1 0.04152 1 del_xq21.33 46 (12%) 323 3e-05 0.0179 0.00021 0.111 0.81496 1 0.03533 1 0.0081699 1 0.052119 1 0.17446 1 0.20418 1 0.52301 1 0.092439 1