Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.1 0.217 48.0 -9999.0 0.0 48.0 KIRREL 0.002 0.053 -9999.0 0.0 -0.292 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.1 -9999.0 0.0 -0.217 48.0 48.0 PLCG1 0.024 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.018 0.122 -9999.0 0.0 -0.218 55.0 55.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.033 0.094 -9999.0 0.0 -0.213 51.0 51.0 FYN -0.037 0.108 0.211 12.0 -0.209 54.0 66.0 mol:Ca2+ -0.019 0.114 -9999.0 0.0 -0.217 49.0 49.0 mol:DAG -0.019 0.115 -9999.0 0.0 -0.218 49.0 49.0 NPHS2 -0.058 0.155 -9999.0 0.0 -0.38 50.0 50.0 mol:IP3 -0.019 0.115 -9999.0 0.0 -0.218 49.0 49.0 regulation of endocytosis -0.021 0.106 -9999.0 0.0 -0.197 54.0 54.0 Nephrin/NEPH1/podocin/Cholesterol -0.029 0.114 -9999.0 0.0 -0.184 89.0 89.0 establishment of cell polarity -0.021 0.1 -9999.0 0.0 -0.217 48.0 48.0 Nephrin/NEPH1/podocin/NCK1-2 -0.007 0.119 -9999.0 0.0 -0.2 52.0 52.0 Nephrin/NEPH1/beta Arrestin2 -0.02 0.108 -9999.0 0.0 -0.199 54.0 54.0 NPHS1 -0.041 0.121 -9999.0 0.0 -0.29 49.0 49.0 Nephrin/NEPH1/podocin -0.025 0.11 -9999.0 0.0 -0.207 57.0 57.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.018 0.116 -9999.0 0.0 -0.218 49.0 49.0 CD2AP 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.019 0.123 -9999.0 0.0 -0.218 55.0 55.0 GRB2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.041 0.107 0.219 12.0 -0.202 54.0 66.0 cytoskeleton organization -0.046 0.102 0.206 2.0 -0.237 50.0 52.0 Nephrin/NEPH1 -0.009 0.069 -9999.0 0.0 -0.145 46.0 46.0 Nephrin/NEPH1/ZO-1 -0.003 0.087 -9999.0 0.0 -0.171 45.0 45.0