Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.168 0.305 0.685 121.0 -9999.0 0.0 121.0 KIRREL -0.073 0.241 -9999.0 0.0 -0.839 44.0 44.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.169 0.305 -9999.0 0.0 -0.687 121.0 121.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.131 0.242 -9999.0 0.0 -0.535 121.0 121.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.077 0.196 -9999.0 0.0 -0.407 121.0 121.0 FYN -0.111 0.236 -9999.0 0.0 -0.507 121.0 121.0 mol:Ca2+ -0.13 0.239 -9999.0 0.0 -0.529 121.0 121.0 mol:DAG -0.131 0.24 -9999.0 0.0 -0.532 121.0 121.0 NPHS2 -0.017 0.052 -9999.0 0.0 -0.888 1.0 1.0 mol:IP3 -0.131 0.24 -9999.0 0.0 -0.532 121.0 121.0 regulation of endocytosis -0.116 0.214 -9999.0 0.0 -0.473 121.0 121.0 Nephrin/NEPH1/podocin/Cholesterol -0.133 0.245 -9999.0 0.0 -0.544 121.0 121.0 establishment of cell polarity -0.168 0.305 -9999.0 0.0 -0.685 121.0 121.0 Nephrin/NEPH1/podocin/NCK1-2 -0.12 0.222 -9999.0 0.0 -0.49 121.0 121.0 Nephrin/NEPH1/beta Arrestin2 -0.103 0.226 -9999.0 0.0 -0.48 121.0 121.0 NPHS1 -0.153 0.319 -9999.0 0.0 -0.816 92.0 92.0 Nephrin/NEPH1/podocin -0.125 0.231 -9999.0 0.0 -0.51 121.0 121.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.131 0.242 -9999.0 0.0 -0.535 121.0 121.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.131 0.242 -9999.0 0.0 -0.535 121.0 121.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.114 0.246 -9999.0 0.0 -0.51 125.0 125.0 cytoskeleton organization -0.103 0.256 -9999.0 0.0 -0.532 121.0 121.0 Nephrin/NEPH1 -0.129 0.236 -9999.0 0.0 -0.524 121.0 121.0 Nephrin/NEPH1/ZO-1 -0.14 0.255 -9999.0 0.0 -0.569 121.0 121.0