Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.101 0.245 0.527 115.0 -9999.0 0.0 115.0 KIRREL -0.046 0.196 -9999.0 0.0 -0.686 41.0 41.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.101 0.245 -9999.0 0.0 -0.528 115.0 115.0 PLCG1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.056 0.204 -9999.0 0.0 -0.429 106.0 106.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.058 0.159 -9999.0 0.0 -0.349 103.0 103.0 FYN -0.064 0.196 0.271 25.0 -0.404 106.0 131.0 mol:Ca2+ -0.056 0.2 -9999.0 0.0 -0.424 105.0 105.0 mol:DAG -0.056 0.201 -9999.0 0.0 -0.426 105.0 105.0 NPHS2 -0.005 0.053 -9999.0 0.0 -0.732 1.0 1.0 mol:IP3 -0.056 0.201 -9999.0 0.0 -0.426 105.0 105.0 regulation of endocytosis -0.05 0.18 -9999.0 0.0 -0.383 103.0 103.0 Nephrin/NEPH1/podocin/Cholesterol -0.068 0.198 -9999.0 0.0 -0.425 108.0 108.0 establishment of cell polarity -0.101 0.245 -9999.0 0.0 -0.527 115.0 115.0 Nephrin/NEPH1/podocin/NCK1-2 -0.04 0.196 -9999.0 0.0 -0.398 105.0 105.0 Nephrin/NEPH1/beta Arrestin2 -0.049 0.183 -9999.0 0.0 -0.388 103.0 103.0 NPHS1 -0.103 0.259 -9999.0 0.0 -0.668 84.0 84.0 Nephrin/NEPH1/podocin -0.061 0.189 -9999.0 0.0 -0.406 106.0 106.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.055 0.203 -9999.0 0.0 -0.428 105.0 105.0 CD2AP 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.055 0.201 -9999.0 0.0 -0.429 103.0 103.0 GRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.078 0.195 0.277 21.0 -0.409 107.0 128.0 cytoskeleton organization -0.082 0.199 -9999.0 0.0 -0.449 102.0 102.0 Nephrin/NEPH1 -0.072 0.184 -9999.0 0.0 -0.396 111.0 111.0 Nephrin/NEPH1/ZO-1 -0.069 0.211 -9999.0 0.0 -0.453 106.0 106.0