Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.09 0.205 -9999.0 0.0 -0.537 47.0 47.0 MAP3K8 0.01 0.033 -9999.0 0.0 -0.351 3.0 3.0 FOS -0.061 0.164 -9999.0 0.0 -0.48 43.0 43.0 PRKCA -0.012 0.087 -9999.0 0.0 -0.352 30.0 30.0 PTPN7 0.009 0.036 0.264 6.0 -9999.0 0.0 6.0 HRAS 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.013 0.088 -9999.0 0.0 -0.352 31.0 31.0 NRAS 0.022 0.002 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.023 0.033 0.218 1.0 -9999.0 0.0 1.0 MAPK3 -0.029 0.136 -9999.0 0.0 -0.682 16.0 16.0 MAP2K1 -0.059 0.153 -9999.0 0.0 -0.402 70.0 70.0 ELK1 0.006 0.027 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.041 0.127 -9999.0 0.0 -0.362 61.0 61.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 157.0 157.0 MAPK1 -0.036 0.142 -9999.0 0.0 -0.591 23.0 23.0 RAF1 -0.041 0.133 -9999.0 0.0 -0.382 59.0 59.0 KRAS 0.022 0.014 0.329 1.0 -9999.0 0.0 1.0