Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	24 (43%)	32	0.04854	1	0.75387	1	0.81743	1	0.90161	1	0.52322	1	0.28123	1	0.61259	1	0.71895	1
1q gain	31 (55%)	25	0.33197	1	0.76553	1	0.76317	1	0.62112	1	0.70277	1	0.46192	1	0.97724	1	0.32223	1
2p gain	23 (41%)	33	0.72566	1	0.0078399	1	0.01862	1	0.057829	1	0.49178	1	0.072419	1	0.29535	1	0.15904	1
2q gain	21 (38%)	35	0.66717	1	0.01827	1	0.01197	1	0.1133	1	0.62168	1	0.04864	1	0.3704	1	0.17231	1
3p gain	12 (21%)	44	0.38769	1	0.26292	1	0.4372	1	0.19991	1	0.86141	1	0.26505	1	0.95964	1	0.63901	1
3q gain	23 (41%)	33	0.2206	1	0.04859	1	0.19375	1	0.12099	1	0.49625	1	0.18815	1	0.51382	1	0.18153	1
4p gain	9 (16%)	47	1	1	0.70306	1	0.82422	1	0.86533	1	0.77474	1	0.32649	1	0.82207	1	0.48582	1
4q gain	3 (5%)	53	0.58113	1	0.25765	1	0.51405	1	0.79161	1	0.67619	1	0.56857	1	0.68702	1	0.59461	1
5p gain	23 (41%)	33	0.39635	1	0.37826	1	0.45094	1	0.24212	1	0.74073	1	0.02803	1	0.91225	1	0.12	1
5q gain	8 (14%)	48	0.77966	1	0.56527	1	0.30788	1	0.24805	1	0.079199	1	0.15426	1	0.23929	1	0.16384	1
6p gain	30 (54%)	26	0.33406	1	0.52231	1	0.60138	1	0.41624	1	1	1	0.47389	1	0.93845	1	0.32047	1
6q gain	27 (48%)	29	0.36611	1	0.20878	1	0.22024	1	0.16261	1	1	1	0.18986	1	0.84203	1	0.19593	1
7p gain	21 (38%)	35	0.54775	1	0.55761	1	0.15351	1	0.27953	1	0.58966	1	0.12784	1	0.35411	1	0.36674	1
7q gain	17 (30%)	39	0.46485	1	0.84053	1	0.33957	1	0.808	1	0.74262	1	0.16618	1	0.58959	1	0.47003	1
8p gain	19 (34%)	37	0.0127	1	0.74283	1	0.44246	1	0.87299	1	0.97082	1	0.55567	1	0.83513	1	0.34121	1
8q gain	30 (54%)	26	0.0050899	1	0.19624	1	0.04914	1	0.50526	1	0.21817	1	0.32583	1	0.21519	1	0.45265	1
9p gain	6 (11%)	50	0.46572	1	0.70286	1	0.93632	1	0.66459	1	0.83257	1	0.80386	1	0.79976	1	0.66817	1
10p gain	21 (38%)	35	0.93453	1	0.01981	1	0.04037	1	0.11795	1	0.32615	1	0.10599	1	0.51645	1	0.43777	1
10q gain	17 (30%)	39	1	1	0.33938	1	0.55262	1	0.04753	1	0.22255	1	0.18055	1	0.42011	1	0.26345	1
11p gain	5 (9%)	51	0.48268	1	0.4409	1	0.26466	1	0.8504	1	0.4954	1	0.1186	1	0.35428	1	0.35205	1
11q gain	7 (12%)	49	0.16952	1	0.38586	1	0.22698	1	0.37923	1	0.7515	1	0.03522	1	0.72626	1	0.097969	1
12p gain	22 (39%)	34	0.47791	1	0.00457	1	0.37231	1	0.04199	1	0.81177	1	0.97659	1	0.80624	1	0.71552	1
12q gain	11 (20%)	45	0.55294	1	0.53279	1	0.80684	1	0.52242	1	1	1	0.29529	1	0.52998	1	0.6323	1
13q gain	15 (27%)	41	0.66871	1	0.071179	1	0.02123	1	0.02358	1	0.22313	1	0.046	1	0.065469	1	0.19198	1
14q gain	7 (12%)	49	0.36559	1	0.575	1	0.25905	1	0.25965	1	0.20577	1	0.73296	1	0.21281	1	0.45668	1
15q gain	4 (7%)	52	0.38642	1	0.25583	1	0.57926	1	0.3246	1	0.75689	1	0.34834	1	0.52927	1	0.41253	1
16p gain	10 (18%)	46	0.03969	1	0.27934	1	0.19528	1	0.27792	1	1	1	0.48237	1	0.71772	1	0.53065	1
16q gain	6 (11%)	50	0.2668	1	0.8486	1	0.54848	1	0.96772	1	0.7704	1	0.92553	1	0.91647	1	0.90979	1
17p gain	9 (16%)	47	0.21573	1	0.89542	1	0.56759	1	0.56146	1	0.28385	1	0.060049	1	0.27127	1	0.33121	1
17q gain	18 (32%)	38	0.92999	1	0.27213	1	0.70111	1	0.51556	1	0.39185	1	0.30354	1	0.73092	1	0.42075	1
18p gain	18 (32%)	38	1	1	0.04952	1	0.092679	1	0.34325	1	0.14628	1	0.19811	1	0.42166	1	0.65359	1
18q gain	14 (25%)	42	0.65902	1	0.080589	1	0.15251	1	0.24146	1	0.20332	1	0.088239	1	0.211	1	0.44875	1
19p gain	24 (43%)	32	0.52328	1	0.17709	1	0.26793	1	0.37053	1	0.53651	1	0.22967	1	0.42175	1	0.74574	1
19q gain	28 (50%)	28	0.38484	1	0.077069	1	0.37727	1	0.39634	1	0.92868	1	0.89921	1	0.5782	1	1	1
20p gain	37 (66%)	19	0.93275	1	0.50376	1	0.92226	1	0.76081	1	0.8776	1	0.69484	1	0.86252	1	0.82358	1
20q gain	44 (79%)	12	0.5196	1	0.91772	1	0.96861	1	0.99646	1	0.58551	1	0.57536	1	0.43043	1	0.73911	1
21q gain	18 (32%)	38	0.23229	1	0.37719	1	0.90043	1	0.89199	1	0.91534	1	0.57388	1	1	1	0.96916	1
22q gain	8 (14%)	48	0.53529	1	0.95968	1	0.80176	1	0.92634	1	0.88535	1	0.94287	1	0.85223	1	0.98913	1
xq gain	14 (25%)	42	0.92241	1	0.42465	1	0.87862	1	0.82353	1	0.96138	1	0.58172	1	1	1	0.78542	1
1p loss	9 (16%)	47	0.051959	1	0.60046	1	0.92066	1	0.11961	1	0.11013	1	0.03012	1	0.12667	1	0.01763	1
1q loss	9 (16%)	47	0.02321	1	0.51451	1	0.51702	1	0.079909	1	0.42034	1	0.1544	1	0.38513	1	0.0308	1
3p loss	20 (36%)	36	0.071089	1	0.42295	1	0.04953	1	0.22928	1	0.37389	1	0.92823	1	0.59978	1	0.40585	1
3q loss	14 (25%)	42	0.56035	1	0.45987	1	0.13781	1	0.6037	1	0.52585	1	0.88104	1	0.65465	1	0.074999	1
4p loss	31 (55%)	25	0.058639	1	0.062489	1	0.25813	1	0.20168	1	0.03717	1	0.71366	1	0.28694	1	0.38573	1
4q loss	33 (59%)	23	0.065579	1	0.01757	1	0.0051599	1	0.03874	1	2e-04	0.123	0.24943	1	0.01839	1	0.10452	1
5p loss	9 (16%)	47	0.71337	1	0.47517	1	0.8844	1	0.13473	1	1	1	0.29987	1	1	1	0.04524	1
5q loss	18 (32%)	38	0.92922	1	0.30409	1	0.26677	1	0.23162	1	0.36213	1	0.94765	1	0.14712	1	0.84119	1
6p loss	5 (9%)	51	0.31574	1	0.95625	1	0.75543	1	0.95638	1	0.54303	1	0.91174	1	0.74347	1	0.61547	1
6q loss	7 (12%)	49	0.01898	1	0.69616	1	0.641	1	0.90126	1	0.70424	1	0.61739	1	0.72618	1	0.44889	1
7p loss	13 (23%)	43	0.41247	1	0.66649	1	0.73444	1	0.50138	1	0.31449	1	0.45544	1	0.48091	1	0.7607	1
7q loss	13 (23%)	43	0.086109	1	0.85389	1	0.92112	1	0.82337	1	0.71108	1	0.22268	1	0.63904	1	0.77015	1
8p loss	23 (41%)	33	0.03266	1	0.9824	1	0.82671	1	0.7461	1	0.68795	1	0.51415	1	0.83905	1	0.85422	1
8q loss	9 (16%)	47	0.18479	1	0.75976	1	0.29748	1	0.71352	1	0.94938	1	0.75679	1	1	1	0.85592	1
9p loss	34 (61%)	22	0.03602	1	0.0079099	1	0.67348	1	0.13661	1	0.86352	1	0.29082	1	0.86913	1	0.11732	1
9q loss	39 (70%)	17	0.061519	1	0.0014	0.86	0.49405	1	0.03844	1	0.66383	1	0.11676	1	0.91848	1	0.38213	1
10p loss	23 (41%)	33	0.82741	1	0.01373	1	0.02873	1	0.18454	1	0.24438	1	0.78846	1	0.44364	1	0.85512	1
10q loss	21 (38%)	35	1	1	0.29819	1	0.17657	1	0.17199	1	0.1253	1	0.47346	1	0.20497	1	0.84659	1
11p loss	26 (46%)	30	0.88107	1	0.00375	1	0.37859	1	0.5179	1	0.27015	1	0.57974	1	0.23756	1	0.2291	1
11q loss	24 (43%)	32	0.77383	1	0.0080799	1	0.80513	1	0.89644	1	0.29459	1	0.59022	1	0.41553	1	0.37526	1
12p loss	13 (23%)	43	0.19328	1	0.27678	1	0.58087	1	0.73192	1	0.54672	1	0.58158	1	0.27485	1	0.4909	1
12q loss	14 (25%)	42	0.51874	1	0.88022	1	0.81984	1	0.91673	1	0.96305	1	0.90808	1	0.45021	1	0.95892	1
13q loss	26 (46%)	30	0.77874	1	0.00113	0.695	0.058029	1	0.02758	1	0.35272	1	0.12074	1	0.25973	1	0.24827	1
14q loss	27 (48%)	29	1	1	0.091999	1	0.12337	1	0.12419	1	0.61759	1	0.89864	1	0.63056	1	0.94716	1
15q loss	32 (57%)	24	0.0052799	1	0.71115	1	0.93082	1	0.98079	1	0.93118	1	0.9776	1	0.89248	1	0.81046	1
16p loss	32 (57%)	24	0.40353	1	0.49446	1	0.34545	1	0.10033	1	0.81047	1	0.91356	1	0.89416	1	0.92534	1
16q loss	37 (66%)	19	0.31969	1	0.79439	1	0.44971	1	0.089379	1	0.68568	1	0.92239	1	0.37888	1	0.91472	1
17p loss	34 (61%)	22	0.40154	1	0.28595	1	0.98076	1	0.75723	1	0.80583	1	0.89119	1	0.41445	1	0.78438	1
17q loss	17 (30%)	39	0.92845	1	0.35735	1	0.71324	1	0.38397	1	0.96786	1	0.21291	1	0.79321	1	0.62249	1
18p loss	18 (32%)	38	0.60221	1	0.0169	1	0.055289	1	0.090579	1	0.067289	1	0.079939	1	0.32631	1	0.30505	1
18q loss	20 (36%)	36	0.21496	1	0.070679	1	0.18554	1	0.11934	1	0.01198	1	0.0053999	1	0.063009	1	0.03092	1
19p loss	15 (27%)	41	0.92557	1	0.46623	1	0.20397	1	0.35602	1	0.34962	1	0.71758	1	0.71451	1	0.36236	1
19q loss	13 (23%)	43	1	1	0.15242	1	0.94483	1	0.61552	1	0.22794	1	0.8716	1	0.69225	1	0.35008	1
20p loss	7 (12%)	49	0.42667	1	0.20658	1	0.082879	1	0.075099	1	0.61856	1	0.69311	1	0.72729	1	0.7575	1
20q loss	4 (7%)	52	1	1	0.60207	1	0.11848	1	0.47135	1	1	1	0.88545	1	1	1	0.85352	1
21q loss	17 (30%)	39	0.86122	1	0.17842	1	0.63272	1	0.748	1	0.68325	1	0.97171	1	1	1	0.94568	1
22q loss	33 (59%)	23	0.82469	1	0.9691	1	0.96229	1	0.90052	1	0.70686	1	0.28965	1	0.63947	1	0.61638	1
xq loss	19 (34%)	37	0.45714	1	0.32488	1	0.32284	1	0.87269	1	0.52955	1	0.9725	1	0.54804	1	0.62552	1