Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q TP53 51 (89%) 6 0.33139 1 0.62705 1 0.87672 1 0.51292 1 1 1 0.91138 1 1 1 1 1 FBXW7 22 (39%) 35 0.063129 1 0.72337 1 0.63338 1 0.10231 1 0.47032 1 0.93072 1 0.97545 1 0.71182 1 PPP2R1A 16 (28%) 41 1 1 0.70913 1 0.5915 1 0.67261 1 0.56984 1 0.31827 1 0.23695 1 0.48968 1 PTEN 11 (19%) 46 0.01104 1 0.00012 0.0125 0.00231 0.238 0.04519 1 0.096399 1 0.061239 1 0.02231 1 0.12206 1 KRAS 7 (12%) 50 0.32051 1 0.01483 1 0.03251 1 0.0060899 0.615 0.46172 1 0.090569 1 0.51349 1 0.0479 1 ZBTB7B 6 (11%) 51 0.4832 1 0.94023 1 1 1 0.91318 1 0.099499 1 0.14645 1 0.1501 1 0.30297 1 CHD4 10 (18%) 47 0.19928 1 0.01014 1 0.18691 1 0.0057599 0.588 0.47934 1 0.41221 1 0.49344 1 0.47883 1 PIK3R1 6 (11%) 51 0.85503 1 0.9391 1 0.54649 1 0.70458 1 0.42636 1 0.50582 1 0.74266 1 0.74733 1 ARHGAP35 6 (11%) 51 1 1 0.33273 1 1 1 0.4015 1 1 1 0.18814 1 1 1 0.25317 1 PIK3CA 20 (35%) 37 0.2564 1 0.9004 1 0.36501 1 0.36952 1 0.11144 1 0.34035 1 0.16464 1 0.11059 1 MAMLD1 4 (7%) 53 0.82612 1 0.90048 1 0.68685 1 0.76889 1 0.063809 1 0.67933 1 0.16332 1 0.57188 1 RB1 6 (11%) 51 0.54393 1 0.089439 1 0.078339 1 0.098079 1 0.83514 1 0.86179 1 0.91967 1 0.68772 1 LYPLA2 3 (5%) 54 1 1 0.62085 1 0.67319 1 0.34886 1 0.38149 1 0.56425 1 0.47774 1 0.49024 1