		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
amp_1p34.2	40 (22%)	144	0.3289	1	0.62911	1	0.24265	1	0.37715	1	0.74395	1	0.32516	1	0.79953	1	0.54677	1
amp_1q23.3	93 (51%)	91	0.00182	1	0.12461	1	0.091629	1	0.89584	1	0.16917	1	0.84084	1	0.01948	1	0.80909	1
amp_1q42.3	96 (52%)	88	2e-05	0.0126	0.3138	1	0.14092	1	0.26476	1	0.29904	1	0.28412	1	0.14867	1	0.26097	1
amp_2q14.2	60 (33%)	124	0.35269	1	0.30673	1	0.58001	1	0.089159	1	0.25141	1	0.20899	1	0.27073	1	0.31969	1
amp_2q31.1	60 (33%)	124	0.03199	1	0.23222	1	0.61873	1	0.16879	1	0.54342	1	0.26956	1	0.10187	1	0.65433	1
amp_3q26.2	128 (70%)	56	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	2e-05	0.0126	9.9999e-06	0.0068	3e-05	0.0188
amp_4q21.1	34 (18%)	150	0.29528	1	0.70115	1	0.04197	1	0.8275	1	0.9541	1	0.42623	1	0.92112	1	0.35803	1
amp_5p15.33	98 (53%)	86	9.9999e-06	0.0068	0.01533	1	0.065799	1	0.01131	1	0.00027	0.163	0.00386	1	0.01035	1	0.00226	1
amp_6p21.1	69 (38%)	115	0.00305	1	0.12343	1	0.31012	1	0.20266	1	0.00341	1	0.00188	1	0.0069699	1	0.00125	0.702
amp_6q23.3	42 (23%)	142	0.03688	1	0.069789	1	0.22263	1	0.30692	1	0.03272	1	0.03095	1	0.0092699	1	0.0067199	1
amp_7p11.2	126 (68%)	58	0.33141	1	0.11057	1	0.48273	1	0.02066	1	0.03754	1	0.26789	1	0.66964	1	0.12839	1
amp_7q21.2	114 (62%)	70	0.47666	1	0.15803	1	0.59503	1	0.7551	1	0.34601	1	0.60804	1	0.77111	1	0.14057	1
amp_8p23.1	52 (28%)	132	4e-05	0.0248	0.00225	1	0.04451	1	0.01533	1	0.00406	1	0.01486	1	0.00028	0.168	0.00177	0.979
amp_8p11.21	85 (46%)	99	0.49328	1	0.17391	1	0.04406	1	0.074179	1	0.3871	1	0.96596	1	0.73412	1	0.68714	1
amp_8q24.21	145 (79%)	39	0.0023	1	0.02214	1	0.01537	1	0.086439	1	0.0067199	1	0.098699	1	0.35332	1	0.14664	1
amp_9p13.3	40 (22%)	144	0.083099	1	0.1043	1	0.02966	1	0.84856	1	0.71513	1	0.13181	1	0.53469	1	0.55302	1
amp_9q34.3	64 (35%)	120	0.02589	1	0.17711	1	0.02941	1	0.95888	1	0.27099	1	0.11277	1	0.11524	1	0.67824	1
amp_11p13	52 (28%)	132	0.14194	1	0.4611	1	0.45934	1	0.51243	1	0.20387	1	0.12614	1	0.58207	1	0.25387	1
amp_11p13	50 (27%)	134	0.086379	1	0.92789	1	0.56103	1	0.87371	1	0.96301	1	0.7116	1	0.7853	1	0.4946	1
amp_11q13.3	104 (57%)	80	9.9999e-06	0.0068	0.00321	1	0.11379	1	0.00161	0.897	0.00112	0.634	0.0012	0.676	0.092089	1	0.00146	0.815
amp_12p12.1	79 (43%)	105	0.03359	1	0.12817	1	0.18273	1	0.03725	1	0.060389	1	0.084439	1	0.057849	1	0.087159	1
amp_12q15	51 (28%)	133	0.13388	1	0.5953	1	0.49631	1	0.56467	1	0.31548	1	0.59845	1	0.29581	1	0.17747	1
amp_13q22.1	65 (35%)	119	0.00173	0.958	0.0066799	1	0.22281	1	0.01084	1	0.00028	0.168	0.00223	1	0.01197	1	0.00026	0.157
amp_14q21.1	61 (33%)	123	0.00023	0.139	0.0090499	1	0.066419	1	0.0082999	1	0.00368	1	0.004	1	0.056909	1	0.01261	1
amp_15q26.1	58 (32%)	126	0.0082099	1	0.071739	1	0.02756	1	0.00366	1	0.0066199	1	0.04166	1	0.03645	1	0.01498	1
amp_17q12	75 (41%)	109	0.00448	1	0.00418	1	0.12522	1	0.26465	1	0.00205	1	0.01977	1	0.02411	1	0.00166	0.921
amp_18p11.32	69 (38%)	115	0.058999	1	0.10779	1	0.23665	1	0.44466	1	0.01697	1	0.5595	1	0.36458	1	0.51068	1
amp_18q11.2	59 (32%)	125	0.01238	1	0.01003	1	0.00111	0.629	0.00088999	0.507	0.00031	0.184	0.0088499	1	0.01477	1	0.00081999	0.471
amp_19p13.2	32 (17%)	152	0.40581	1	0.082989	1	0.82171	1	0.39573	1	0.12125	1	0.39475	1	0.32162	1	0.68503	1
amp_19q12	54 (29%)	130	0.00476	1	0.15551	1	0.0060399	1	0.04381	1	0.03889	1	0.27207	1	0.12346	1	0.051489	1
amp_xq28	69 (38%)	115	0.061029	1	0.03127	1	0.0113	1	0.03578	1	0.02915	1	0.00193	1	0.36529	1	0.00367	1
del_1p36.11	75 (41%)	109	0.01075	1	0.0090799	1	0.00066999	0.388	0.20522	1	0.00305	1	0.02338	1	0.04226	1	0.03857	1
del_1p13.2	64 (35%)	120	5.9999e-05	0.0369	0.098179	1	0.01439	1	0.54521	1	0.75549	1	0.10386	1	0.17175	1	0.90232	1
del_1q44	17 (9%)	167	0.85548	1	0.74297	1	0.8041	1	0.49626	1	0.71762	1	0.64246	1	0.80231	1	0.25547	1
del_2q22.1	59 (32%)	125	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-05	0.061	0.00050999	0.299	9.9999e-06	0.0068	2e-05	0.0126	0.00013	0.0792	9.9999e-06	0.0068
del_2q33.3	36 (20%)	148	0.29283	1	0.065899	1	0.15854	1	0.064179	1	0.01339	1	0.069529	1	0.072809	1	0.02767	1
del_3p26.2	111 (60%)	73	9.9999e-06	0.0068	3e-05	0.0188	0.00058999	0.345	0.00108	0.613	0.00019	0.115	0.00017	0.103	0.01298	1	3e-04	0.178
del_3p14.3	126 (68%)	58	9.9999e-06	0.0068	9.9999e-06	0.0068	0.00029	0.173	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068
del_3p14.2	125 (68%)	59	9.9999e-06	0.0068	2e-05	0.0126	0.00112	0.634	5.9999e-05	0.0369	9.9999e-06	0.0068	9.9999e-06	0.0068	4e-05	0.0248	9.9999e-06	0.0068
del_3q11.1	33 (18%)	151	0.5917	1	0.62304	1	0.38539	1	0.6402	1	0.86316	1	0.79215	1	0.88605	1	0.62915	1
del_3q26.31	16 (9%)	168	0.00227	1	3e-05	0.0188	0.087569	1	0.00353	1	3e-04	0.178	0.00035	0.207	0.00223	1	6.9999e-05	0.0429
del_4p15.2	106 (58%)	78	0.0054799	1	0.098019	1	0.0053099	1	0.29155	1	0.04779	1	0.74678	1	0.26488	1	0.95373	1
del_4q22.1	105 (57%)	79	0.00019	0.115	0.11049	1	0.00051999	0.304	0.23859	1	0.00299	1	0.14305	1	0.051569	1	0.03621	1
del_4q34.3	99 (54%)	85	5e-04	0.293	0.0061899	1	4e-04	0.236	0.056209	1	0.00082999	0.476	0.00308	1	0.01964	1	0.00198	1
del_5q12.1	112 (61%)	72	0.00046	0.271	0.00070999	0.41	0.36089	1	1	1	0.02244	1	0.02554	1	0.43594	1	0.057509	1
del_6p25.3	74 (40%)	110	0.01612	1	0.02238	1	0.074059	1	0.52213	1	0.12294	1	0.02154	1	0.3126	1	0.091549	1
del_6q16.3	55 (30%)	129	0.14232	1	0.43581	1	0.02813	1	0.18224	1	0.12684	1	0.50804	1	0.54076	1	0.2837	1
del_6q26	50 (27%)	134	0.27173	1	0.92728	1	0.03923	1	0.17617	1	0.19592	1	0.73219	1	0.77259	1	0.33287	1
del_7q31.1	56 (30%)	128	0.2241	1	0.086779	1	0.073079	1	0.59313	1	0.40127	1	0.096119	1	0.10979	1	0.02354	1
del_7q36.3	67 (36%)	117	0.90554	1	0.70867	1	0.25493	1	0.75312	1	0.36104	1	0.14983	1	0.37725	1	0.16313	1
del_8p23.2	90 (49%)	94	8.9999e-05	0.0551	0.02799	1	0.1937	1	0.18501	1	0.0093999	1	0.10794	1	0.03679	1	0.14644	1
del_8p12	75 (41%)	109	0.00029	0.173	0.41078	1	0.75839	1	0.52588	1	0.22739	1	0.80458	1	0.5525	1	0.49366	1
del_9p23	108 (59%)	76	0.41625	1	0.12067	1	0.25056	1	0.060729	1	0.42675	1	0.72309	1	0.91497	1	0.69473	1
del_9p21.3	141 (77%)	43	9.9999e-06	0.0068	0.23561	1	0.29708	1	0.02956	1	0.03398	1	0.10355	1	0.30635	1	0.10582	1
del_10p15.3	54 (29%)	130	0.00076999	0.444	0.01974	1	0.29112	1	0.02089	1	0.0061299	1	0.01163	1	0.088919	1	0.061219	1
del_10p11.21	52 (28%)	132	9.9999e-06	0.0068	3e-05	0.0188	0.00134	0.749	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	0.00047	0.276	3e-05	0.0188
del_10q21.1	46 (25%)	138	0.00218	1	0.02032	1	0.36076	1	0.1974	1	0.01732	1	0.057589	1	0.23369	1	0.0495	1
del_10q23.31	65 (35%)	119	0.02153	1	0.03632	1	0.72927	1	0.44582	1	0.11896	1	0.28159	1	0.37074	1	0.45332	1
del_11p15.4	79 (43%)	105	0.1292	1	0.04479	1	0.62508	1	0.68567	1	0.62535	1	0.1824	1	0.80493	1	0.4584	1
del_11q25	81 (44%)	103	3e-05	0.0188	0.02799	1	0.69431	1	0.21659	1	0.057369	1	0.081949	1	0.02767	1	0.02984	1
del_12q23.1	51 (28%)	133	0.25098	1	0.01883	1	0.31958	1	0.18808	1	0.10128	1	0.1333	1	0.18087	1	0.04603	1
del_13q12.11	76 (41%)	108	0.00021	0.127	0.0134	1	0.0079099	1	0.00232	1	0.0086499	1	0.0091999	1	0.01333	1	0.01577	1
del_13q14.2	74 (40%)	110	0.00162	0.901	0.0050499	1	0.01095	1	0.011	1	0.01714	1	0.02464	1	0.02259	1	0.02533	1
del_13q21.31	69 (38%)	115	0.01297	1	0.052939	1	0.20157	1	0.083359	1	0.088069	1	0.13444	1	0.092599	1	0.13486	1
del_14q23.3	51 (28%)	133	0.00363	1	0.01527	1	0.0081199	1	0.01414	1	0.093479	1	0.01312	1	0.02802	1	0.00221	1
del_15q11.2	63 (34%)	121	0.40405	1	0.15948	1	0.094059	1	0.6273	1	0.20191	1	0.01891	1	0.64037	1	0.00374	1
del_16p13.3	65 (35%)	119	2e-05	0.0126	4e-05	0.0248	0.00028	0.168	0.00058999	0.345	3e-05	0.0188	9.9999e-06	0.0068	4e-05	0.0248	9.9999e-06	0.0068
del_16q23.1	84 (46%)	100	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068
del_17p12	86 (47%)	98	8.9999e-05	0.0551	9.9999e-06	0.0068	0.0013	0.728	0.00062999	0.365	9.9999e-06	0.0068	9.9999e-06	0.0068	0.01003	1	2e-05	0.0126
del_17q25.3	41 (22%)	143	0.37203	1	0.81838	1	0.68879	1	0.90214	1	0.13024	1	0.53795	1	0.03704	1	0.70984	1
del_18p11.23	60 (33%)	124	0.31376	1	0.0057499	1	0.44292	1	0.52224	1	0.02533	1	0.13678	1	0.13934	1	0.04809	1
del_18q12.2	111 (60%)	73	0.094309	1	0.01738	1	0.12526	1	0.28505	1	0.04447	1	0.00059999	0.349	0.03553	1	0.00027	0.163
del_18q21.2	119 (65%)	65	0.15116	1	0.00082999	0.476	0.085349	1	0.171	1	0.00463	1	0.00202	1	0.01554	1	0.00060999	0.354
del_18q22.3	112 (61%)	72	0.96182	1	0.03554	1	0.069769	1	0.60732	1	0.21354	1	0.0078499	1	0.05	1	0.00070999	0.41
del_19p13.3	93 (51%)	91	4e-04	0.236	0.30168	1	0.72261	1	0.76958	1	0.03577	1	0.02264	1	0.11332	1	0.0066499	1
del_19q11	48 (26%)	136	0.21498	1	0.38691	1	0.56016	1	0.35027	1	0.35108	1	0.01454	1	0.00091999	0.523	0.02698	1
del_20p12.1	33 (18%)	151	0.034	1	0.16106	1	0.43551	1	0.053789	1	0.01658	1	0.04995	1	0.28941	1	0.04088	1
del_21q11.2	107 (58%)	77	0.12403	1	0.02756	1	0.3051	1	0.6044	1	0.04983	1	0.16996	1	0.15094	1	0.095869	1
del_21q21.1	107 (58%)	77	0.12393	1	0.0084599	1	0.096449	1	0.34203	1	0.087459	1	0.17384	1	0.072829	1	0.073749	1
del_21q22.12	108 (59%)	76	0.10256	1	0.01098	1	0.087899	1	0.43106	1	0.03238	1	0.33008	1	0.071929	1	0.2042	1
del_22q11.1	79 (43%)	105	9.9999e-06	0.0068	9.9999e-06	0.0068	0.00244	1	0.01518	1	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068	9.9999e-06	0.0068
del_xp21.1	69 (38%)	115	0.00081999	0.471	0.03706	1	0.003	1	0.077749	1	0.054769	1	0.15978	1	0.11399	1	0.15047	1
del_xp11.3	74 (40%)	110	0.00085999	0.491	0.16345	1	0.00127	0.712	0.00119	0.671	0.00306	1	0.04515	1	0.03354	1	0.0179	1
del_xq11.2	42 (23%)	142	0.49457	1	0.24319	1	0.89514	1	0.48509	1	0.12628	1	0.2197	1	0.20378	1	0.71508	1
del_xq21.33	40 (22%)	144	0.16002	1	0.20592	1	0.226	1	0.1874	1	0.10265	1	0.02884	1	0.15246	1	0.18491	1
