		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
3p gain	8 (12%)	58	0.27195	1	0.53033	1	0.95114	1	0.6473	1	0.51571	1	0.69136	1	0.66904	1	0.59999	1
3q gain	8 (12%)	58	0.26987	1	0.52957	1	0.95158	1	0.64804	1	0.51487	1	0.69013	1	0.66904	1	0.60241	1
4p gain	24 (36%)	42	0.055439	1	1	1	2e-05	0.00934	5.9999e-05	0.0272	0.76896	1	0.0090299	1	0.034911	1	0.01727	1
4q gain	24 (36%)	42	0.055619	1	1	1	2e-05	0.00934	5e-05	0.0228	0.772	1	0.0090799	1	0.034911	1	0.01731	1
5p gain	8 (12%)	58	0.42406	1	0.68071	1	0.44848	1	0.44342	1	0.36738	1	0.058429	1	1	1	0.12623	1
5q gain	8 (12%)	58	0.42353	1	0.68324	1	0.44897	1	0.44533	1	0.36201	1	0.060189	1	1	1	0.12705	1
7p gain	24 (36%)	42	0.15025	1	1	1	0.01595	1	0.060879	1	0.89945	1	0.11732	1	0.76563	1	0.099089	1
7q gain	24 (36%)	42	0.1518	1	1	1	0.01663	1	0.061799	1	0.90114	1	0.11922	1	0.76563	1	0.099529	1
8p gain	17 (26%)	49	0.41274	1	0.4166	1	0.0036	1	0.03173	1	0.46361	1	0.10088	1	1	1	0.02922	1
8q gain	18 (27%)	48	0.34331	1	0.37658	1	0.00108	0.459	0.0096399	1	0.69618	1	0.087789	1	0.75145	1	0.04241	1
9p gain	10 (15%)	56	1	1	1	1	0.72326	1	0.81294	1	0.83347	1	0.60156	1	1	1	0.26495	1
9q gain	10 (15%)	56	1	1	1	1	0.72306	1	0.81278	1	0.83116	1	0.5991	1	1	1	0.26247	1
10p gain	4 (6%)	62	0.44138	1	0.16246	1	0.51671	1	0.20361	1	1	1	0.16666	1	1	1	0.45758	1
11p gain	15 (23%)	51	0.2801	1	0.67633	1	3e-05	0.0138	0.00023	0.102	0.87058	1	0.02788	1	0.19654	1	0.078869	1
11q gain	15 (23%)	51	0.28111	1	0.67857	1	9.9999e-06	0.00488	5e-05	0.0228	0.61818	1	0.01933	1	0.19654	1	0.10417	1
12p gain	19 (29%)	47	0.48059	1	0.76675	1	0.079689	1	0.15793	1	1	1	0.066689	1	0.2129	1	0.15575	1
12q gain	20 (30%)	46	0.44387	1	0.59497	1	0.14515	1	0.082419	1	0.94282	1	0.03226	1	0.23522	1	0.1321	1
14q gain	21 (32%)	45	0.10626	1	0.82924	1	0.00086999	0.373	0.0051399	1	0.42651	1	0.056599	1	0.031178	1	0.077319	1
15q gain	21 (32%)	45	0.10631	1	0.83041	1	0.00171	0.718	0.062129	1	0.75677	1	0.21528	1	0.76221	1	0.47251	1
16p gain	21 (32%)	45	0.10694	1	1	1	2e-05	0.00934	7.9999e-05	0.0361	0.15922	1	0.0054099	1	0.031178	1	0.0073999	1
16q gain	21 (32%)	45	0.10628	1	1	1	2e-05	0.00934	8.9999e-05	0.0405	0.16155	1	0.0053099	1	0.031178	1	0.0071399	1
18p gain	17 (26%)	49	0.51831	1	0.80545	1	0.00194	0.811	0.01298	1	0.93744	1	0.04953	1	0.34059	1	0.0472	1
18q gain	16 (24%)	50	0.63997	1	0.92645	1	0.00099999	0.428	0.01891	1	0.82119	1	0.051909	1	0.11865	1	0.062299	1
19p gain	19 (29%)	47	0.48303	1	0.27349	1	0.02152	1	0.0079899	1	0.65999	1	0.03903	1	1	1	0.70808	1
19q gain	17 (26%)	49	0.51769	1	0.31034	1	0.00137	0.578	0.00166	0.699	0.41129	1	0.04749	1	1	1	0.65482	1
20p gain	20 (30%)	46	0.21575	1	0.59459	1	0.0296	1	0.03173	1	0.70826	1	0.03054	1	0.53518	1	0.18197	1
20q gain	21 (32%)	45	0.22689	1	0.38627	1	0.067539	1	0.01676	1	0.67677	1	0.03691	1	0.76221	1	0.099059	1
21q gain	4 (6%)	62	0.43842	1	0.16275	1	0.51255	1	0.10628	1	0.67444	1	0.16542	1	1	1	0.40952	1
22q gain	19 (29%)	47	0.90138	1	0.71191	1	0.069979	1	0.36105	1	0.55151	1	0.02332	1	1	1	0.0093499	1
xq gain	6 (9%)	60	1	1	0.72179	1	0.0067599	1	0.12122	1	0.26353	1	0.11844	1	0.14179	1	0.071419	1
1p loss	53 (80%)	13	0.67192	1	2e-05	0.00934	0.00048	0.209	0.00033	0.145	0.16225	1	0.0013	0.55	0.17642	1	0.00411	1
1q loss	52 (79%)	14	0.47373	1	9.9999e-06	0.00488	6.9999e-05	0.0317	5e-05	0.0228	0.2315	1	0.00050999	0.221	0.17642	1	0.00402	1
2p loss	46 (70%)	20	0.088819	1	9.9999e-06	0.00488	9.9999e-06	0.00488	9.9999e-06	0.00488	0.081469	1	9.9999e-06	0.00488	0.030584	1	0.00072999	0.314
2q loss	46 (70%)	20	0.088809	1	9.9999e-06	0.00488	9.9999e-06	0.00488	9.9999e-06	0.00488	0.081359	1	9.9999e-06	0.00488	0.030584	1	0.00061999	0.268
3p loss	9 (14%)	57	0.03616	1	0.89472	1	0.064469	1	0.00299	1	0.90293	1	0.20048	1	0.3805	1	0.84522	1
3q loss	8 (12%)	58	0.02068	1	0.36729	1	0.02428	1	0.00187	0.784	0.57135	1	0.1821	1	0.14179	1	0.68866	1
5p loss	10 (15%)	56	0.098399	1	0.25266	1	0.00065999	0.284	0.01934	1	0.42507	1	0.01467	1	0.45109	1	0.34359	1
5q loss	10 (15%)	56	0.099149	1	0.25344	1	0.00062999	0.272	0.0191	1	0.42545	1	0.01444	1	0.45109	1	0.34531	1
6p loss	51 (77%)	15	0.33151	1	0.00014	0.0626	3e-05	0.0138	9.9999e-06	0.00488	0.35198	1	0.00118	0.5	0.17642	1	4e-04	0.175
6q loss	51 (77%)	15	0.33094	1	0.00016	0.071	3e-05	0.0138	9.9999e-06	0.00488	0.35137	1	0.00104	0.444	0.17642	1	0.00032	0.14
8p loss	9 (14%)	57	9.9999e-06	0.00488	0.083779	1	0.054699	1	0.03874	1	0.14983	1	0.46737	1	0.14179	1	0.31968	1
8q loss	8 (12%)	58	2e-05	0.00934	0.04464	1	0.13379	1	0.071779	1	0.28963	1	0.52897	1	0.14179	1	0.32037	1
9p loss	10 (15%)	56	1	1	0.90375	1	0.064389	1	0.01633	1	0.90947	1	0.60261	1	0.69505	1	0.89077	1
9q loss	10 (15%)	56	1	1	0.9027	1	0.063669	1	0.01677	1	0.91157	1	0.6011	1	0.69505	1	0.89012	1
10p loss	48 (73%)	18	0.34303	1	0.00029	0.128	6.9999e-05	0.0317	9.9999e-06	0.00488	0.2757	1	0.00014	0.0626	0.75898	1	0.01015	1
10q loss	49 (74%)	17	0.24653	1	0.00031	0.136	2e-05	0.00934	9.9999e-06	0.00488	0.22451	1	2e-04	0.0886	0.53841	1	0.00338	1
11p loss	7 (11%)	59	0.63054	1	0.57496	1	0.10908	1	0.31684	1	0.20534	1	0.93678	1	0.3805	1	0.5789	1
11q loss	7 (11%)	59	0.62758	1	0.57282	1	0.10928	1	0.31659	1	0.20435	1	0.93704	1	0.3805	1	0.5751	1
13q loss	43 (65%)	23	0.26075	1	0.00049	0.213	0.00331	1	0.00015	0.0667	0.8504	1	0.19603	1	0.54105	1	0.0059899	1
16p loss	4 (6%)	62	0.68335	1	0.5209	1	0.02305	1	0.03658	1	0.67629	1	0.087519	1	0.2864	1	0.98505	1
16q loss	5 (8%)	61	0.72138	1	0.38743	1	0.0059599	1	0.0066599	1	0.42723	1	0.04972	1	0.072436	1	0.68849	1
17p loss	50 (76%)	16	0.29836	1	9.9999e-06	0.00488	9.9999e-06	0.00488	9.9999e-06	0.00488	0.051829	1	8.9999e-05	0.0405	0.049144	1	0.00211	0.88
17q loss	50 (76%)	16	0.29794	1	9.9999e-06	0.00488	9.9999e-06	0.00488	9.9999e-06	0.00488	0.051389	1	9.9999e-05	0.0448	0.049144	1	0.00212	0.882
18p loss	8 (12%)	58	0.67654	1	0.096449	1	0.31478	1	0.21226	1	0.72006	1	0.94923	1	0.66904	1	0.7709	1
18q loss	10 (15%)	56	0.62178	1	0.079909	1	0.44292	1	0.28125	1	0.57228	1	0.86415	1	0.69505	1	0.5121	1
19q loss	3 (5%)	63	0.64412	1	0.76484	1	0.76711	1	0.82319	1	0.516	1	0.86443	1	1	1	0.82077	1
20p loss	4 (6%)	62	0.29963	1	0.80668	1	0.21058	1	0.21537	1	0.45109	1	0.65898	1	0.2864	1	0.55051	1
20q loss	3 (5%)	63	1	1	0.4157	1	0.22613	1	0.058069	1	0.29512	1	0.82558	1	0.056025	1	0.71726	1
21q loss	35 (53%)	31	0.77391	1	0.01054	1	0.2488	1	0.19466	1	1	1	0.12776	1	1	1	0.04248	1
22q loss	8 (12%)	58	0.82931	1	0.13341	1	0.24594	1	0.23365	1	0.89778	1	0.21397	1	0.68742	1	0.35674	1
xq loss	39 (59%)	27	0.59897	1	0.073519	1	0.0068899	1	0.00361	1	0.32652	1	0.00107	0.456	0.77013	1	0.03721	1
