		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	57 (15%)	313	0.29123	1	0.72162	1	0.16187	1	0.091769	1	0.96631	1	0.03956	1	0.11081	1	0.02258	1
1q gain	222 (60%)	148	9.9999e-06	0.0064	2e-05	0.0122	9.9999e-06	0.0064	5e-05	0.0298	0.15636	1	0.0052399	1	0.41387	1	0.052459	1
2p gain	44 (12%)	326	0.16114	1	0.23244	1	0.02002	1	0.00013	0.0762	0.55326	1	0.93911	1	0.0098199	1	0.38389	1
2q gain	41 (11%)	329	0.084629	1	0.084309	1	0.01183	1	0.00046	0.262	0.69451	1	0.76046	1	0.00317	1	0.37357	1
3p gain	35 (9%)	335	0.0379	1	0.50044	1	0.29766	1	0.20449	1	0.13415	1	0.51927	1	0.02321	1	0.25402	1
3q gain	38 (10%)	332	0.29802	1	0.67344	1	0.4015	1	0.31082	1	0.21515	1	0.51026	1	0.01482	1	0.6124	1
4p gain	27 (7%)	343	0.01512	1	0.0336	1	0.071129	1	0.02188	1	0.29862	1	0.44312	1	0.067719	1	0.20319	1
4q gain	7 (2%)	363	0.79952	1	0.57024	1	0.46031	1	0.30872	1	0.24549	1	0.84897	1	0.27656	1	0.55509	1
5p gain	135 (36%)	235	2e-04	0.116	0.00086999	0.483	0.51089	1	0.41635	1	0.22603	1	0.17738	1	0.30045	1	0.58343	1
5q gain	107 (29%)	263	0.00393	1	0.01449	1	0.16263	1	0.9813	1	0.64289	1	0.85248	1	0.92823	1	0.89153	1
6p gain	117 (32%)	253	9.9999e-06	0.0064	0.00039	0.223	0.00149	0.805	0.0078999	1	0.14471	1	0.00297	1	0.32477	1	0.1035	1
6q gain	67 (18%)	303	0.00078999	0.441	0.097479	1	0.01556	1	0.058909	1	0.2012	1	0.1869	1	0.20329	1	0.38739	1
7p gain	111 (30%)	259	0.04579	1	0.27173	1	0.50527	1	0.03191	1	0.04291	1	0.072639	1	0.25761	1	0.33605	1
7q gain	111 (30%)	259	0.37611	1	0.03537	1	0.88145	1	0.055169	1	0.21889	1	0.20883	1	0.52326	1	0.33923	1
8p gain	80 (22%)	290	2e-05	0.0122	0.15646	1	0.12869	1	0.28287	1	0.01107	1	0.11389	1	0.14705	1	0.01611	1
8q gain	188 (51%)	182	9.9999e-06	0.0064	0.49047	1	5e-05	0.0298	0.0062899	1	0.02849	1	0.00365	1	0.13202	1	3e-04	0.173
9p gain	19 (5%)	351	0.46627	1	0.52621	1	0.44496	1	0.55762	1	0.70572	1	0.39921	1	0.098099	1	0.36472	1
9q gain	21 (6%)	349	0.084929	1	0.66136	1	0.096119	1	0.04115	1	0.76662	1	0.41328	1	0.11198	1	0.2315	1
10p gain	61 (16%)	309	0.00056999	0.321	0.00122	0.665	0.00079999	0.446	0.00038	0.218	0.27474	1	0.41981	1	0.022	1	0.01813	1
10q gain	37 (10%)	333	0.00103	0.566	5e-04	0.284	9.9999e-06	0.0064	0.0050699	1	0.064279	1	0.0411	1	0.03783	1	0.03299	1
11p gain	17 (5%)	353	0.47331	1	0.19126	1	0.39388	1	0.069469	1	0.30233	1	0.47046	1	0.01508	1	0.27394	1
11q gain	18 (5%)	352	0.91167	1	0.72163	1	0.6665	1	0.42125	1	0.36721	1	0.70133	1	0.17831	1	0.34369	1
12p gain	41 (11%)	329	0.01685	1	0.12773	1	0.00256	1	9.9999e-06	0.0064	0.78418	1	0.3698	1	0.00145	0.784	0.02357	1
12q gain	47 (13%)	323	0.02332	1	0.42007	1	0.00203	1	9.9999e-06	0.0064	0.34117	1	0.62203	1	0.00057999	0.327	0.070869	1
13q gain	23 (6%)	347	0.0095799	1	0.18369	1	0.00161	0.863	0.12404	1	0.077599	1	0.29359	1	0.18058	1	0.21379	1
14q gain	23 (6%)	347	0.45263	1	0.29008	1	0.053669	1	0.17721	1	0.75978	1	0.14933	1	0.066949	1	0.65115	1
15q gain	33 (9%)	337	0.64694	1	0.53731	1	0.38501	1	0.32573	1	0.84922	1	0.28717	1	0.53009	1	0.83042	1
16p gain	31 (8%)	339	0.17428	1	0.96226	1	0.57707	1	0.9126	1	0.76851	1	0.25391	1	0.10104	1	0.3182	1
16q gain	17 (5%)	353	0.90655	1	0.060429	1	0.0080199	1	0.51116	1	0.12498	1	0.91291	1	0.15939	1	0.70649	1
17p gain	30 (8%)	340	0.10081	1	0.03428	1	0.0412	1	0.0091799	1	0.3994	1	0.75679	1	0.052619	1	0.14071	1
17q gain	95 (26%)	275	0.00158	0.848	0.0089999	1	0.41298	1	0.0066899	1	0.0196	1	0.00044	0.251	0.60785	1	0.02318	1
18p gain	36 (10%)	334	0.02241	1	0.11658	1	0.00029	0.168	0.00017	0.0993	0.76785	1	0.19204	1	0.087299	1	0.45663	1
18q gain	28 (8%)	342	0.02009	1	0.35282	1	0.00444	1	0.00026	0.151	0.82994	1	0.054549	1	0.01928	1	0.28383	1
19p gain	56 (15%)	314	0.58142	1	0.00233	1	8.9999e-05	0.0533	0.00174	0.927	0.01428	1	0.0050499	1	0.00076999	0.43	0.03755	1
19q gain	72 (19%)	298	0.39554	1	0.00052999	0.299	2e-05	0.0122	0.00073999	0.414	0.00034	0.196	0.00088999	0.492	4e-05	0.024	0.00072999	0.41
20p gain	108 (29%)	262	9.9999e-06	0.0064	0.0058899	1	0.01063	1	0.00017	0.0993	0.16938	1	0.03201	1	9.9999e-05	0.0591	0.074989	1
20q gain	112 (30%)	258	9.9999e-06	0.0064	0.01131	1	0.01201	1	9.9999e-05	0.0591	0.30747	1	0.075339	1	5e-05	0.0298	0.086819	1
21q gain	26 (7%)	344	0.17947	1	0.17027	1	0.03862	1	0.01952	1	0.92522	1	0.22749	1	0.24866	1	0.52537	1
22q gain	48 (13%)	322	4e-05	0.024	0.18288	1	0.00012	0.0706	9.9999e-06	0.0064	0.60606	1	0.73685	1	0.00219	1	0.13615	1
xq gain	62 (17%)	308	0.00044	0.251	0.03674	1	0.066969	1	0.097879	1	0.0084299	1	0.00341	1	0.21196	1	0.00094999	0.524
1p loss	81 (22%)	289	0.00284	1	9.9999e-06	0.0064	4e-05	0.024	0.00177	0.942	0.00424	1	0.0077399	1	0.00062999	0.354	0.0042	1
1q loss	22 (6%)	348	0.36995	1	0.6872	1	0.10948	1	0.17971	1	0.35489	1	0.24405	1	0.28745	1	0.061919	1
2p loss	33 (9%)	337	0.059589	1	1	1	0.33635	1	0.04817	1	0.37577	1	0.70887	1	0.19802	1	0.268	1
2q loss	38 (10%)	332	0.18532	1	1	1	0.24084	1	0.02366	1	0.25607	1	0.59511	1	0.60287	1	0.40611	1
3p loss	52 (14%)	318	0.03242	1	0.42977	1	0.00154	0.83	0.00011	0.0648	0.0079099	1	0.32216	1	0.00173	0.924	0.04974	1
3q loss	40 (11%)	330	0.32777	1	0.67382	1	0.01265	1	0.01112	1	0.078229	1	0.3156	1	0.0052499	1	0.2725	1
4p loss	107 (29%)	263	9.9999e-06	0.0064	0.01339	1	0.00281	1	0.01587	1	0.98814	1	0.01875	1	0.0049	1	0.00288	1
4q loss	148 (40%)	222	9.9999e-06	0.0064	0.00342	1	0.00114	0.625	0.0057299	1	0.24764	1	0.0059999	1	3e-05	0.0181	0.0088699	1
5p loss	28 (8%)	342	0.02486	1	0.71857	1	0.13526	1	0.12539	1	0.26433	1	0.098049	1	0.0089899	1	0.01887	1
5q loss	39 (11%)	331	0.00287	1	0.03824	1	0.01322	1	0.00154	0.83	0.53467	1	0.04598	1	0.00094999	0.524	0.00134	0.728
6p loss	28 (8%)	342	0.64498	1	0.59232	1	0.13329	1	0.67117	1	0.67476	1	0.72121	1	0.26959	1	0.24142	1
6q loss	92 (25%)	278	0.18444	1	0.37478	1	0.00483	1	0.45796	1	0.52267	1	0.14077	1	0.671	1	0.83086	1
7p loss	16 (4%)	354	0.36426	1	0.14232	1	0.42431	1	0.92535	1	0.87903	1	0.22512	1	0.0063399	1	0.0392	1
7q loss	21 (6%)	349	0.43477	1	0.13198	1	0.02538	1	0.48826	1	0.56182	1	0.02672	1	0.00014	0.0819	0.0052999	1
8p loss	190 (51%)	180	0.00012	0.0706	0.01844	1	0.03526	1	0.39981	1	0.24334	1	0.02936	1	0.45151	1	0.43805	1
8q loss	43 (12%)	327	0.00141	0.764	0.59282	1	0.32618	1	0.64198	1	0.76262	1	0.93461	1	0.69076	1	0.90154	1
9p loss	118 (32%)	252	5.9999e-05	0.0356	0.01596	1	0.01081	1	0.00463	1	0.10794	1	0.0092099	1	0.0305	1	0.01208	1
9q loss	107 (29%)	263	0.00031	0.179	0.00212	1	0.04518	1	0.00087999	0.488	0.27287	1	0.01616	1	0.11445	1	0.00167	0.893
10p loss	45 (12%)	325	0.02427	1	0.17631	1	0.01543	1	0.2451	1	0.61344	1	0.0063599	1	0.39399	1	0.02039	1
10q loss	76 (21%)	294	0.0091899	1	0.30249	1	2e-05	0.0122	0.092579	1	0.31159	1	3e-05	0.0181	0.45334	1	2e-05	0.0122
11p loss	65 (18%)	305	0.46308	1	0.84263	1	0.03109	1	0.0091699	1	0.64393	1	0.17539	1	0.00121	0.661	0.0052999	1
11q loss	73 (20%)	297	0.1438	1	0.29381	1	0.14395	1	0.052339	1	0.65817	1	0.3022	1	0.00315	1	0.0165	1
12p loss	65 (18%)	305	0.00081999	0.456	0.03603	1	0.02558	1	0.49203	1	0.40755	1	0.16175	1	0.62234	1	0.43225	1
12q loss	36 (10%)	334	0.088039	1	0.51178	1	0.04178	1	0.85284	1	0.87743	1	0.91442	1	0.69574	1	0.93383	1
13q loss	122 (33%)	248	0.00017	0.0993	0.49495	1	0.02272	1	0.00462	1	0.00304	1	0.00471	1	0.01901	1	0.00126	0.685
14q loss	107 (29%)	263	9.9999e-06	0.0064	0.051169	1	3e-05	0.0181	9.9999e-06	0.0064	0.48032	1	0.1761	1	0.00038	0.218	0.01637	1
15q loss	67 (18%)	303	0.057019	1	0.27765	1	0.00483	1	9.9999e-06	0.0064	0.15358	1	0.25001	1	3e-05	0.0181	0.01751	1
16p loss	109 (29%)	261	3e-05	0.0181	0.01874	1	9.9999e-06	0.0064	9.9999e-06	0.0064	0.00382	1	9.9999e-06	0.0064	9.9999e-06	0.0064	9.9999e-06	0.0064
16q loss	145 (39%)	225	9.9999e-06	0.0064	5e-05	0.0298	9.9999e-06	0.0064	9.9999e-06	0.0064	0.16824	1	9.9999e-06	0.0064	9.9999e-06	0.0064	9.9999e-06	0.0064
17p loss	185 (50%)	185	9.9999e-06	0.0064	0.02815	1	0.01438	1	0.51818	1	0.00351	1	0.00042	0.24	0.44642	1	5e-04	0.284
17q loss	39 (11%)	331	0.37053	1	0.77557	1	0.33187	1	0.57144	1	0.17795	1	0.62578	1	0.26854	1	0.46166	1
18p loss	74 (20%)	296	0.04878	1	0.00371	1	0.54931	1	0.30972	1	0.52732	1	0.71064	1	0.069019	1	0.22285	1
18q loss	79 (21%)	291	0.00423	1	0.00115	0.629	0.59208	1	0.33497	1	0.20456	1	0.40541	1	0.1161	1	0.30522	1
19p loss	55 (15%)	315	9.9999e-06	0.0064	0.25769	1	0.083019	1	0.15454	1	0.14889	1	0.080019	1	0.28385	1	0.00343	1
19q loss	39 (11%)	331	9.9999e-06	0.0064	0.2271	1	0.0098199	1	0.093859	1	0.03094	1	0.15349	1	0.46987	1	0.24578	1
20p loss	26 (7%)	344	0.26502	1	0.21556	1	0.52934	1	0.15959	1	0.087019	1	0.854	1	0.7138	1	0.3041	1
20q loss	13 (4%)	357	0.34951	1	0.38594	1	0.26281	1	0.2325	1	0.46428	1	0.63898	1	0.01375	1	0.25467	1
21q loss	110 (30%)	260	0.00051999	0.294	0.87275	1	0.00107	0.587	0.0063599	1	0.49685	1	0.93198	1	0.12133	1	0.30905	1
22q loss	70 (19%)	300	0.03643	1	0.35223	1	0.0057799	1	0.31722	1	0.50663	1	0.46155	1	0.10535	1	0.87542	1
xq loss	73 (20%)	297	0.0053099	1	0.25303	1	0.56054	1	0.8212	1	0.44437	1	0.75887	1	0.22025	1	0.83074	1
