		Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	18 (10%)	166	0.42637	1	0.38256	1	0.01718	1	0.0076199	1	0.76125	1	0.7375	1	1	1	0.93779	1	0.13432	1	0.89365	1
1q gain	50 (27%)	134	0.0078999	1	0.00162	1	0.23548	1	0.36638	1	0.01262	1	0.061949	1	0.0055099	1	0.0387	1	0.00032	0.235	0.01141	1
2p gain	14 (8%)	170	0.02109	1	0.00298	1	0.1007	1	0.59208	1	0.63554	1	0.18772	1	0.43561	1	0.01513	1	0.12922	1	0.099809	1
2q gain	16 (9%)	168	0.03569	1	0.0090799	1	0.1003	1	0.59368	1	0.46629	1	0.18254	1	0.51616	1	0.00476	1	0.2006	1	0.03999	1
3p gain	10 (5%)	174	0.01335	1	0.18838	1	0.26546	1	0.68452	1	0.54174	1	0.61785	1	0.83973	1	0.4424	1	0.53027	1	0.52679	1
3q gain	20 (11%)	164	0.00049	0.356	0.00225	1	0.33346	1	0.16057	1	0.2657	1	0.27816	1	0.77264	1	0.059019	1	0.17511	1	0.26506	1
4p gain	11 (6%)	173	0.01538	1	0.78344	1	0.85935	1	0.23951	1	0.00148	1	0.0096699	1	0.0354	1	0.02108	1	0.78011	1	0.20844	1
4q gain	8 (4%)	176	0.00071999	0.515	0.41115	1	0.86137	1	0.23886	1	0.02208	1	0.03407	1	0.02169	1	0.04041	1	0.52084	1	0.15448	1
5p gain	28 (15%)	156	9.9999e-06	0.00782	0.77648	1	0.60037	1	0.37027	1	0.66779	1	0.15681	1	0.24146	1	0.12431	1	0.0063899	1	0.4566	1
5q gain	20 (11%)	164	9.9999e-06	0.00782	0.6001	1	0.71063	1	0.22005	1	0.32515	1	0.01031	1	0.10951	1	0.03395	1	0.11517	1	0.14533	1
6p gain	7 (4%)	177	0.00041	0.3	0.67939	1	0.49435	1	0.48629	1	0.88731	1	1	1	0.9073	1	0.87536	1	0.059179	1	1	1
6q gain	5 (3%)	179	0.0165	1	0.44139	1	NA	NA	NA	NA	0.8514	1	1	1	1	1	1	1	0.03113	1	0.45277	1
7p gain	52 (28%)	132	9.9999e-06	0.00782	0.01039	1	0.071779	1	0.29166	1	0.35291	1	0.26811	1	0.27608	1	0.04722	1	0.0054699	1	0.16396	1
7q gain	48 (26%)	136	9.9999e-06	0.00782	0.055329	1	0.2129	1	0.67298	1	0.75788	1	0.25937	1	0.66895	1	0.34004	1	0.02241	1	0.45109	1
8p gain	26 (14%)	158	0.00364	1	0.04213	1	0.55795	1	0.49185	1	0.75796	1	0.958	1	0.22156	1	0.55226	1	0.01282	1	0.66243	1
8q gain	48 (26%)	136	5.9999e-05	0.0447	0.00071999	0.515	0.46855	1	0.49283	1	0.29431	1	0.54373	1	0.39589	1	0.079319	1	0.00104	0.734	0.067609	1
9p gain	8 (4%)	176	0.01169	1	1	1	0.5948	1	0.52181	1	0.591	1	0.63485	1	0.6835	1	0.78709	1	0.57677	1	0.44659	1
9q gain	12 (7%)	172	6.9999e-05	0.052	0.6711	1	0.7663	1	0.68369	1	0.92625	1	0.61187	1	0.6283	1	0.26337	1	0.26335	1	0.28007	1
10p gain	10 (5%)	174	0.03626	1	0.13008	1	0.01393	1	0.12402	1	0.21389	1	0.81483	1	0.47408	1	0.90021	1	0.00069999	0.501	1	1
10q gain	13 (7%)	171	0.02638	1	0.04994	1	0.02794	1	0.079549	1	0.14765	1	0.38104	1	0.29719	1	0.91397	1	0.00037	0.271	1	1
11p gain	13 (7%)	171	0.00071999	0.515	0.04854	1	0.04526	1	0.67353	1	0.75489	1	1	1	0.72515	1	0.79215	1	0.43175	1	0.75098	1
11q gain	15 (8%)	169	0.0061599	1	0.061189	1	0.01657	1	0.20482	1	0.9389	1	0.93725	1	0.50249	1	0.53484	1	0.28409	1	0.18039	1
12p gain	30 (16%)	154	9.9999e-06	0.00782	0.0064499	1	0.3209	1	0.25145	1	0.67699	1	0.25537	1	0.11031	1	0.069349	1	0.0022	1	0.45717	1
12q gain	22 (12%)	162	9.9999e-06	0.00782	0.02271	1	0.35294	1	0.30617	1	0.58596	1	0.11105	1	0.20735	1	0.04054	1	0.00403	1	0.15637	1
13q gain	29 (16%)	155	0.01655	1	0.60161	1	0.34972	1	0.65631	1	0.21123	1	0.47181	1	0.21736	1	0.12371	1	0.43068	1	0.79466	1
14q gain	26 (14%)	158	9.9999e-06	0.00782	0.33033	1	0.58476	1	0.89368	1	0.27573	1	0.57564	1	0.16892	1	0.26713	1	0.1033	1	0.92478	1
15q gain	14 (8%)	170	0.089869	1	0.10765	1	0.14198	1	0.59622	1	0.34286	1	0.13132	1	0.24709	1	1	1	0.25469	1	0.86596	1
16p gain	22 (12%)	162	2e-05	0.0151	0.0042	1	0.01648	1	0.24982	1	0.15275	1	0.058529	1	0.066829	1	0.01451	1	0.00205	1	0.02888	1
16q gain	23 (12%)	161	9.9999e-06	0.00782	0.0076599	1	0.26048	1	0.52821	1	0.10572	1	0.055729	1	0.01307	1	0.00075999	0.54	0.00269	1	0.00322	1
17p gain	9 (5%)	175	4e-05	0.0299	0.0394	1	0.8916	1	0.4951	1	0.0027	1	0.00057999	0.419	0.00084999	0.602	0.00252	1	0.22511	1	0.01001	1
17q gain	17 (9%)	167	0.00046	0.335	0.38848	1	0.97119	1	0.83169	1	0.19105	1	0.062009	1	0.094459	1	0.070649	1	0.11947	1	0.24474	1
18p gain	28 (15%)	156	9.9999e-06	0.00782	0.04487	1	0.21128	1	0.053229	1	0.02682	1	0.1973	1	0.14667	1	0.02184	1	0.03366	1	0.10245	1
18q gain	12 (7%)	172	5e-05	0.0373	0.60133	1	0.6408	1	0.04207	1	0.38028	1	0.49145	1	0.47913	1	0.12409	1	0.3632	1	0.088379	1
19p gain	17 (9%)	167	0.00068999	0.495	0.14344	1	0.47148	1	0.29683	1	0.68377	1	0.62184	1	0.01247	1	0.33671	1	0.38412	1	0.59447	1
19q gain	28 (15%)	156	0.00036	0.264	0.17731	1	0.61228	1	0.52143	1	0.89583	1	0.89079	1	0.068119	1	0.68617	1	0.10733	1	1	1
20p gain	34 (18%)	150	9.9999e-06	0.00782	0.21747	1	0.1353	1	0.45468	1	0.22656	1	0.15412	1	0.21915	1	0.01624	1	0.0064299	1	0.25677	1
20q gain	45 (24%)	139	9.9999e-06	0.00782	0.12638	1	0.41194	1	0.33259	1	0.54485	1	0.17548	1	0.3311	1	0.02338	1	0.00051999	0.376	0.20788	1
22q gain	8 (4%)	176	0.34795	1	0.054189	1	0.2637	1	0.40012	1	0.10567	1	0.079579	1	0.36723	1	0.064919	1	0.14385	1	0.27004	1
xq gain	13 (7%)	171	0.00027	0.199	1	1	0.69886	1	0.4068	1	0.12563	1	0.0093199	1	0.15973	1	0.03675	1	0.81267	1	0.087119	1
1p loss	36 (20%)	148	5.9999e-05	0.0447	0.00433	1	0.00045	0.328	0.00161	1	0.01032	1	0.064219	1	0.16607	1	0.051079	1	0.02855	1	0.02401	1
1q loss	8 (4%)	176	0.04236	1	0.28429	1	0.51647	1	0.7001	1	1	1	0.50859	1	0.76018	1	0.69537	1	0.10255	1	0.78197	1
2p loss	11 (6%)	173	0.0079099	1	0.57305	1	1	1	0.95341	1	0.67087	1	0.19143	1	0.91977	1	0.75931	1	0.26452	1	0.84702	1
2q loss	5 (3%)	179	0.00049	0.356	0.60214	1	NA	NA	NA	NA	0.45122	1	0.090159	1	0.44787	1	0.29528	1	0.15913	1	0.36193	1
3p loss	36 (20%)	148	0.00184	1	0.25603	1	0.19526	1	0.11792	1	0.64971	1	0.9056	1	0.20808	1	0.30093	1	0.10662	1	0.55559	1
3q loss	19 (10%)	165	0.03095	1	0.17277	1	0.0073799	1	0.0056499	1	0.52939	1	0.67199	1	0.78709	1	1	1	0.0074699	1	0.85217	1
4p loss	25 (14%)	159	0.04075	1	0.03143	1	0.40331	1	0.52592	1	0.10498	1	0.10339	1	0.57794	1	0.01158	1	0.95801	1	0.00331	1
4q loss	25 (14%)	159	0.24427	1	0.04918	1	0.5054	1	0.41687	1	0.054359	1	0.18326	1	0.19941	1	0.00273	1	0.70617	1	0.00111	0.781
5p loss	9 (5%)	175	0.00361	1	0.17547	1	0.516	1	0.7001	1	0.91088	1	0.23695	1	0.84118	1	1	1	0.16036	1	0.80386	1
5q loss	13 (7%)	171	0.00381	1	0.0025	1	0.23497	1	0.57577	1	0.9345	1	0.25144	1	0.62159	1	0.44835	1	0.13858	1	0.60065	1
6p loss	64 (35%)	120	9.9999e-06	0.00782	3e-05	0.0225	0.071639	1	0.38809	1	0.13533	1	0.01419	1	0.22095	1	0.00101	0.714	0.00266	1	0.00013	0.0965
6q loss	83 (45%)	101	9.9999e-06	0.00782	2e-05	0.0151	0.0083199	1	0.069749	1	0.00031	0.228	0.00048	0.349	0.00139	0.972	2e-05	0.0151	9.9999e-06	0.00782	2e-05	0.0151
7p loss	3 (2%)	181	0.17791	1	0.31977	1	NA	NA	NA	NA	0.7984	1	0.77364	1	0.42751	1	1	1	0.42958	1	0.31389	1
7q loss	4 (2%)	180	0.070739	1	0.18763	1	0.45462	1	0.41383	1	0.81038	1	1	1	0.53927	1	1	1	0.26442	1	0.56054	1
8p loss	41 (22%)	143	0.00114	0.8	0.01678	1	0.24901	1	0.15507	1	0.14758	1	0.00496	1	0.01527	1	0.01248	1	0.0066699	1	0.00233	1
8q loss	16 (9%)	168	0.01922	1	0.52195	1	0.25066	1	0.22961	1	0.79322	1	0.43697	1	0.33414	1	0.45569	1	0.050119	1	0.16906	1
9p loss	75 (41%)	109	9.9999e-06	0.00782	0.12997	1	0.0087899	1	0.071329	1	0.00287	1	0.03858	1	0.01705	1	0.0145	1	0.0084299	1	0.0073799	1
9q loss	43 (23%)	141	0.11513	1	0.96704	1	0.30251	1	0.38707	1	0.2682	1	0.44122	1	0.19572	1	0.26625	1	0.21896	1	0.31	1
10p loss	36 (20%)	148	0.00024	0.177	0.15757	1	0.4541	1	0.58843	1	0.15965	1	0.1933	1	0.36884	1	0.14802	1	0.063599	1	0.095859	1
10q loss	30 (16%)	154	0.00017	0.126	0.61691	1	0.77116	1	0.71224	1	0.18427	1	0.01695	1	0.53002	1	0.33534	1	0.22753	1	0.098209	1
11p loss	17 (9%)	167	0.00141	0.984	0.04167	1	0.34163	1	0.068939	1	0.9434	1	0.68286	1	0.47602	1	0.48123	1	0.47367	1	0.7282	1
11q loss	16 (9%)	168	0.00065999	0.475	0.45184	1	0.16248	1	0.01384	1	0.78725	1	0.81766	1	0.92979	1	0.5738	1	0.4009	1	0.81995	1
12p loss	20 (11%)	164	0.00018	0.133	0.00078999	0.561	0.00044	0.321	0.00254	1	0.061249	1	0.0086899	1	0.084129	1	0.00108	0.761	0.34298	1	0.00174	1
12q loss	28 (15%)	156	9.9999e-06	0.00782	0.04348	1	0.00191	1	0.00335	1	0.15184	1	0.00285	1	0.12353	1	0.11675	1	0.24148	1	0.02375	1
13q loss	20 (11%)	164	0.00060999	0.44	0.01348	1	0.82894	1	0.83187	1	0.00296	1	0.15546	1	0.0234	1	0.01354	1	0.00179	1	0.061889	1
14q loss	16 (9%)	168	0.23414	1	0.18601	1	0.085689	1	0.1585	1	0.4957	1	0.074199	1	0.37468	1	0.2176	1	0.77096	1	0.57791	1
15q loss	30 (16%)	154	4e-05	0.0299	0.00065999	0.475	0.29481	1	0.55236	1	0.02062	1	0.00212	1	0.079149	1	0.0063299	1	0.10526	1	0.0037	1
16p loss	11 (6%)	173	0.0079099	1	0.28169	1	0.01219	1	0.17418	1	0.67176	1	0.48968	1	0.63145	1	0.42534	1	0.27888	1	0.83727	1
16q loss	13 (7%)	171	0.02439	1	0.10832	1	0.49566	1	0.48791	1	0.7065	1	0.12254	1	0.43003	1	0.2444	1	0.13268	1	0.28304	1
17p loss	80 (43%)	104	9.9999e-06	0.00782	9.9999e-06	0.00782	0.00302	1	0.0062799	1	9.9999e-06	0.00782	9.9999e-06	0.00782	9.9999e-06	0.00782	2e-05	0.0151	9.9999e-06	0.00782	3e-05	0.0225
17q loss	22 (12%)	162	0.00064999	0.468	0.00499	1	0.02226	1	0.24255	1	0.15584	1	0.38881	1	0.51719	1	0.31257	1	0.17821	1	0.31562	1
18p loss	55 (30%)	129	0.12899	1	0.097179	1	0.84698	1	0.442	1	0.6451	1	0.63385	1	0.36286	1	0.90349	1	0.26941	1	0.2742	1
18q loss	106 (58%)	78	9.9999e-06	0.00782	0.00079999	0.567	0.01625	1	0.0085099	1	0.00239	1	0.0052299	1	0.01488	1	0.00344	1	0.04735	1	2e-05	0.0151
19p loss	19 (10%)	165	0.00128	0.896	0.00112	0.787	0.35395	1	0.77913	1	0.062909	1	0.02412	1	0.39014	1	0.0063799	1	2e-04	0.148	0.01949	1
19q loss	12 (7%)	172	0.0069499	1	0.061929	1	0.00481	1	0.29652	1	0.03996	1	0.01497	1	0.48598	1	0.050979	1	0.099429	1	0.074529	1
20p loss	20 (11%)	164	0.00033	0.242	0.0095199	1	0.7282	1	0.67233	1	0.0069399	1	0.091529	1	0.03673	1	0.04117	1	0.00214	1	0.01452	1
20q loss	5 (3%)	179	0.27014	1	0.078309	1	NA	NA	NA	NA	0.38076	1	0.84798	1	0.92049	1	0.82597	1	0.12998	1	0.60267	1
21q loss	58 (32%)	126	9.9999e-06	0.00782	0.00074999	0.534	0.18021	1	0.12215	1	0.02187	1	0.095989	1	0.38862	1	0.03255	1	0.00059999	0.433	0.03625	1
22q loss	46 (25%)	138	9.9999e-06	0.00782	0.01732	1	0.97374	1	0.98931	1	0.21779	1	0.37538	1	0.31053	1	0.03943	1	0.00116	0.813	0.02819	1
xq loss	18 (10%)	166	9.9999e-06	0.00782	0.03365	1	0.33951	1	0.19791	1	0.36928	1	0.32796	1	0.26652	1	0.8345	1	0.49135	1	0.58289	1
