Clinical Features	Time to Death		AGE		NEOPLASM.DISEASESTAGE		PATHOLOGY.T.STAGE		PATHOLOGY.N.STAGE		GENDER		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
ZFPM1	24 (39%)	38	0.34654	1	0.53413	1	0.3107	1	0.97539	1	0.66925	1	1	1	0.67692	1
LACTB	19 (31%)	43	0.72197	1	0.94519	1	0.20054	1	0.092129	1	1	1	0.56782	1	0.65598	1
CCDC102A	17 (27%)	45	0.20388	1	0.47745	1	0.15407	1	0.20705	1	0.16795	1	1	1	1	1
ZNF517	13 (21%)	49	0.74477	1	0.042075	1	0.73701	1	0.75285	1	1	1	0.75624	1	0.30578	1
MAL2	11 (18%)	51	0.9332	1	0.070821	1	0.39453	1	0.04265	1	0.30962	1	0.078935	1	0.29969	1
CLDN23	10 (16%)	52	0.86712	1	0.716	1	0.62514	1	0.78495	1	0.26643	1	0.47182	1	0.5585	1
TOR3A	12 (19%)	50	0.6069	1	0.53269	1	0.19068	1	0.13783	1	0.58197	1	0.73958	1	1	1
USP42	15 (24%)	47	0.51971	1	0.68098	1	0.58756	1	0.82065	1	0.63846	1	0.54086	1	1	1
TP53	12 (19%)	50	0.023206	1	0.78232	1	0.1059	1	0.31667	1	1	1	0.73958	1	0.57981	1
APOE	7 (11%)	55	0.90893	1	0.13307	1	0.92743	1	0.92265	1	1	1	0.086091	1	1	1
ZAR1	11 (18%)	51	0.50881	1	0.67156	1	0.61888	1	0.33737	1	0.30962	1	0.078935	1	0.5585	1
ASPDH	8 (13%)	54	0.26418	1	0.98324	1	0.00348	1	0.34643	1	0.10835	1	0.70029	1	1	1
KCNK17	9 (15%)	53	0.29331	1	0.71895	1	0.89767	1	0.43536	1	0.58292	1	0.70862	1	0.18007	1
LZTR1	6 (10%)	56	0.45563	1	0.46025	1	1	1	1	1	0.49048	1	1	1	1	1
ERCC2	10 (16%)	52	0.72892	1	0.83318	1	0.60674	1	0.61291	1	0.26643	1	1	1	0.5112	1
RINL	8 (13%)	54	0.32409	1	0.62153	1	0.62176	1	0.5229	1	1	1	0.70029	1	0.26837	1
SYT8	8 (13%)	54	0.18972	1	0.40665	1	0.20184	1	0.69513	1	0.58292	1	1	1	0.5585	1
LRIG1	16 (26%)	46	0.57879	1	0.45908	1	0.94197	1	0.72502	1	0.16544	1	0.37529	1	0.64446	1
C1ORF106	9 (15%)	53	0.16614	1	0.38448	1	0.47987	1	0.28218	1	0.22411	1	0.14043	1	0.5585	1
GPRIN2	8 (13%)	54	0.92681	1	0.40073	1	0.89901	1	0.55506	1	0.58292	1	1	1	1	1
CTNNB1	7 (11%)	55	0.23664	1	0.26585	1	0.73083	1	0.93369	1	0.1444	1	0.044325	1	0.5585	1
C16ORF3	5 (8%)	57	0.44861	1	0.75628	1	0.26944	1	0.56457	1	0.4268	1	0.15097	1	1	1
CCDC105	6 (10%)	56	0.4164	1	0.43182	1	0.28957	1	0.10933	1	0.49048	1	0.080787	1	0.5112	1
RGS9BP	8 (13%)	54	0.36459	1	0.98324	1	0.94063	1	0.03806	1	0.54817	1	0.43805	1	0.5112	1
HHIPL1	6 (10%)	56	0.73092	1	0.60024	1	0.73465	1	0.71256	1	0.49048	1	0.65659	1	1	1
C10ORF95	6 (10%)	56	0.97014	1	0.53569	1	0.52424	1	1	1	1	1	1	1	1	1
TSC22D2	8 (13%)	54	0.1082	1	0.62897	1	0.31691	1	0.12988	1	1	1	0.70029	1	0.5112	1
NOXA1	5 (8%)	57	0.71486	1	0.98968	1	0.90066	1	0.8018	1	0.4268	1	0.15097	1	1	1
THEM4	5 (8%)	57	0.38799	1	0.31312	1	0.42974	1	0.39423	1	0.35661	1	0.64731	1	1	1
ATXN1	10 (16%)	52	0.8472	1	0.26265	1	0.78014	1	0.42908	1	1	1	0.082016	1	1	1
PLIN5	5 (8%)	57	0.49676	1	0.58703	1	1	1	0.89922	1	0.4268	1	0.64731	1	0.37433	1
OPRD1	12 (19%)	50	0.81419	1	0.139	1	1	1	1	1	1	1	0.5123	1	1	1
KRTAP4-5	5 (8%)	57	0.14637	1	0.47692	1	0.57927	1	0.36243	1	1	1	0.64731	1	1	1
C19ORF10	7 (11%)	55	0.98894	1	0.53323	1	0.14386	1	0.4526	1	0.54817	1	0.40475	1	1	1
AATK	6 (10%)	56	0.34289	1	0.034003	1	0.64594	1	0.64628	1	0.49048	1	0.40908	1	1	1
SARM1	6 (10%)	56	0.20305	1	0.73877	1	0.69354	1	0.24083	1	1	1	0.65659	1	0.1006	1
TRIOBP	10 (16%)	52	0.83141	1	0.76662	1	0.9529	1	1	1	0.054828	1	0.082016	1	1	1
ZNF598	12 (19%)	50	0.63415	1	0.020975	1	0.5163	1	0.80176	1	0.58197	1	0.018637	1	0.57981	1
WDR34	5 (8%)	57	0.60141	1	0.679	1	1	1	0.74143	1	1	1	0.049287	1	1	1
ZNF628	7 (11%)	55	0.10825	1	0.75539	1	0.46255	1	0.4224	1	1	1	1	1	0.5112	1
BTBD11	6 (10%)	56	0.6622	1	0.86757	1	0.04017	1	0.14935	1	0.49048	1	0.40908	1	1	1
IRX3	5 (8%)	57	0.92429	1	0.31312	1	0.24389	1	0.50754	1	1	1	0.64731	1	1	1
FPGS	5 (8%)	57	0.40363	1	0.31936	1	0.26833	1	0.56461	1	0.4268	1	1	1	1	1
MEN1	5 (8%)	57	0.063357	1	0.6885	1	0.03618	1	0.15861	1	0.35661	1	1	1	0.5112	1
BHLHE22	5 (8%)	57	0.17911	1	0.92787	1	0.32523	1	0.89805	1	0.075853	1	0.64731	1	0.18007	1
DMKN	3 (5%)	59	0.20125	1	0.38445	1	NA	NA	NA	NA	1	1	1	1	1	1
OBSCN	18 (29%)	44	0.64996	1	0.045341	1	0.50639	1	0.86099	1	0.3412	1	0.56134	1	1	1
PANK2	5 (8%)	57	0.066162	1	0.16644	1	0.89978	1	0.63234	1	1	1	0.049287	1	1	1
RREB1	5 (8%)	57	0.80543	1	0.93815	1	0.69326	1	0.24186	1	0.075853	1	1	1	0.37433	1
RNF149	4 (6%)	58	0.19275	1	0.070917	1	0.236	1	0.39632	1	1	1	1	1	1	1
GLTPD2	6 (10%)	56	0.36125	1	0.10025	1	0.69265	1	0.62988	1	1	1	0.65659	1	0.20588	1
SNED1	5 (8%)	57	0.43265	1	0.73669	1	0.13678	1	0.18691	1	0.075853	1	0.64731	1	1	1
TPO	12 (19%)	50	0.62103	1	0.85153	1	0.86585	1	0.91719	1	0.091895	1	1	1	1	1
PTPLA	4 (6%)	58	0.68853	1	0.72009	1	0.6168	1	0.64171	1	1	1	0.61036	1	0.5112	1
PRSS27	3 (5%)	59	0.088089	1	0.41193	1	0.47583	1	0.5281	1	1	1	0.28503	1	0.037433	1
CD320	4 (6%)	58	0.29073	1	0.28237	1	0.16104	1	0.28553	1	1	1	1	1	0.1006	1
SEMA5B	8 (13%)	54	0.80309	1	0.64396	1	0.89808	1	1	1	1	1	0.43805	1	1	1
CCDC150	4 (6%)	58	0.075856	1	0.45607	1	0.03665	1	0.10925	1	0.35661	1	1	1	0.1006	1
TAF5	4 (6%)	58	0.34602	1	0.59588	1	0.32683	1	0.84778	1	0.35661	1	1	1	0.37433	1
GARS	19 (31%)	43	0.0087343	1	0.22458	1	0.0065599	1	0.0059799	1	0.65612	1	1	1	0.64446	1
MUC5B	22 (35%)	40	0.8661	1	0.58097	1	0.77556	1	0.87583	1	0.65316	1	1	1	1	1
KIAA1984	4 (6%)	58	0.89756	1	0.6568	1	0.83403	1	0.52567	1	1	1	0.12354	1	0.5112	1
SRPX	3 (5%)	59	0.95288	1	0.92157	1	0.83657	1	0.63654	1	0.2794	1	0.54627	1	0.5112	1
TNIP2	5 (8%)	57	0.17341	1	0.60496	1	0.11662	1	0.64147	1	0.047778	1	1	1	1	1
IDUA	8 (13%)	54	0.15715	1	0.20374	1	0.10028	1	0.2226	1	1	1	1	1	1	1
RNF39	5 (8%)	57	0.6323	1	0.77602	1	0.37137	1	0.84668	1	0.35661	1	1	1	0.37433	1
PABPC1	4 (6%)	58	0.66572	1	0.39774	1	1	1	1	1	0.35661	1	0.61036	1	0.5585	1
SCRT1	3 (5%)	59	0.02872	1	0.22462	1	0.83659	1	0.33653	1	0.2794	1	0.54627	1	1	1
MAP1S	5 (8%)	57	0.64695	1	0.40058	1	0.39503	1	1	1	0.4268	1	0.3366	1	1	1
NF1	7 (11%)	55	0.2134	1	0.68057	1	0.92752	1	1	1	1	1	0.0064154	1	0.5112	1
AKAP2	4 (6%)	58	0.70711	1	0.58598	1	0.32568	1	0.74126	1	1	1	0.12354	1	NA	NA
NOTCH2	5 (8%)	57	0.48905	1	0.76613	1	0.69262	1	0.46962	1	0.35661	1	1	1	1	1
FANK1	4 (6%)	58	0.71826	1	0.2177	1	0.065999	1	0.089979	1	0.35661	1	0.28736	1	0.5585	1
NEFH	6 (10%)	56	0.15149	1	0.53569	1	1	1	0.41086	1	0.49048	1	1	1	0.18007	1
NPTX1	3 (5%)	59	0.99675	1	0.89555	1	0.25649	1	0.24937	1	1	1	0.28503	1	1	1
KBTBD13	9 (15%)	53	0.47693	1	0.49667	1	0.096179	1	0.12233	1	0.22411	1	0.14043	1	1	1
RASIP1	6 (10%)	56	0.048431	1	0.9905	1	0.67995	1	0.48481	1	0.49048	1	0.40908	1	1	1
AR	4 (6%)	58	0.12482	1	0.78536	1	0.37319	1	0.15873	1	0.35661	1	1	1	1	1
KNDC1	9 (15%)	53	0.21375	1	0.91244	1	0.10975	1	0.062749	1	1	1	0.14043	1	1	1
SEZ6L2	8 (13%)	54	0.63961	1	0.88309	1	0.89854	1	0.66077	1	1	1	1	1	0.30578	1
VARS	6 (10%)	56	0.99074	1	0.83955	1	0.298	1	0.2411	1	1	1	0.1736	1	0.021132	1
IER5	3 (5%)	59	NA	NA	0.58814	1	0.091879	1	0.03462	1	0.2794	1	0.54627	1	1	1
NMU	5 (8%)	57	0.24651	1	0.27167	1	1	1	0.89859	1	0.4268	1	0.15097	1	0.5112	1
TMEM189	3 (5%)	59	NA	NA	0.44055	1	NA	NA	NA	NA	1	1	1	1	0.37433	1
ADAD2	4 (6%)	58	0.97072	1	0.62602	1	0.7033	1	1	1	1	1	0.12354	1	1	1
PLEC	13 (21%)	49	0.45118	1	0.56806	1	0.84672	1	0.82494	1	1	1	0.11215	1	0.64446	1
RGMB	6 (10%)	56	0.37093	1	0.72979	1	0.92827	1	0.64698	1	0.49048	1	1	1	0.30578	1
CLIC6	5 (8%)	57	0.34305	1	0.34515	1	0.47616	1	0.71197	1	1	1	0.64731	1	1	1
ZNF814	3 (5%)	59	NA	NA	0.74276	1	0.0279	1	0.066459	1	1	1	1	1	1	1
DSPP	9 (15%)	53	0.97998	1	0.4124	1	0.7578	1	1	1	0.22411	1	0.47135	1	1	1
AMDHD1	10 (16%)	52	0.84837	1	0.043373	1	0.82578	1	1	1	0.57679	1	0.3066	1	0.5112	1
CRIPAK	10 (16%)	52	0.68934	1	0.11639	1	0.092299	1	0.30556	1	0.57679	1	1	1	1	1
NOM1	6 (10%)	56	0.89538	1	0.62532	1	0.2149	1	0.26557	1	1	1	1	1	1	1
MAP7	3 (5%)	59	0.9695	1	0.73039	1	1	1	1	1	1	1	1	1	1	1
PTX4	3 (5%)	59	5.2886e-05	0.0436	0.30122	1	0.01094	1	0.03538	1	1	1	1	1	1	1
LRP11	6 (10%)	56	0.60662	1	0.49721	1	0.63616	1	1	1	1	1	0.65659	1	0.5585	1
PDCD6	3 (5%)	59	0.91884	1	0.087891	1	0.0106	1	0.00491	1	0.2794	1	1	1	0.20588	1
SHOX2	3 (5%)	59	0.22607	1	0.89555	1	1	1	0.78664	1	0.2794	1	1	1	1	1
UQCRFS1	5 (8%)	57	0.18198	1	0.049335	1	0.03893	1	0.02229	1	0.4268	1	1	1	0.18007	1
CTBP2	3 (5%)	59	0.94196	1	0.24398	1	0.39667	1	0.16919	1	1	1	1	1	0.5112	1
PRKAR1A	6 (10%)	56	0.80666	1	0.83025	1	0.070079	1	0.068109	1	0.49048	1	0.080787	1	0.37433	1
JMJD4	3 (5%)	59	0.75688	1	0.84389	1	1	1	0.63228	1	1	1	0.28503	1	0.37433	1
HSD17B1	4 (6%)	58	0.63812	1	0.59588	1	0.19221	1	0.23927	1	1	1	1	1	0.37433	1
COQ2	5 (8%)	57	0.96218	1	0.12382	1	0.47903	1	0.71061	1	1	1	0.64731	1	1	1
FEZ2	3 (5%)	59	0.69996	1	0.49069	1	0.7016	1	0.78672	1	0.2794	1	1	1	1	1
DLEU7	3 (5%)	59	NA	NA	0.61096	1	0.70513	1	1	1	1	1	1	1	1	1
RNF135	3 (5%)	59	0.22607	1	0.83107	1	0.57708	1	0.78354	1	1	1	1	1	0.5112	1
SPIRE2	3 (5%)	59	0.93592	1	0.063693	1	0.39739	1	0.16738	1	1	1	0.54627	1	0.20588	1
KRTAP5-5	3 (5%)	59	0.31443	1	0.066076	1	0.70588	1	1	1	1	1	0.28503	1	1	1
SGK223	3 (5%)	59	0.74703	1	0.46024	1	0.47716	1	0.52736	1	1	1	0.54627	1	0.37433	1
C9ORF66	5 (8%)	57	0.12986	1	0.35852	1	0.43678	1	0.56307	1	1	1	0.3366	1	0.037433	1
AQP7	3 (5%)	59	0.74703	1	0.043548	1	0.57633	1	0.78671	1	1	1	1	1	1	1
ADAMTS7	4 (6%)	58	0.1721	1	0.12868	1	0.23674	1	0.39638	1	1	1	1	1	1	1
PCDHB13	5 (8%)	57	0.66873	1	0.12701	1	0.35952	1	0.21397	1	1	1	1	1	0.1006	1
CSGALNACT2	3 (5%)	59	0.8352	1	0.70586	1	0.70442	1	1	1	1	1	0.54627	1	1	1
HLA-A	3 (5%)	59	0.35384	1	0.22462	1	1	1	0.63334	1	1	1	0.28503	1	0.20588	1
MTFMT	3 (5%)	59	0.77742	1	0.57689	1	0.70492	1	1	1	1	1	0.040719	1	1	1
NLRP5	4 (6%)	58	0.92387	1	0.052989	1	0.4872	1	0.19568	1	1	1	1	1	1	1
KCNJ11	4 (6%)	58	0.45908	1	0.41393	1	0.03756	1	0.74029	1	0.047778	1	0.61036	1	1	1