Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 4 (4%) 86 0.18302 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 1q gain 8 (9%) 82 0.04301 1 0.65806 1 0.20165 1 0.55927 1 0.04593 1 0.078999 1 0.064629 1 0.24148 1 0.14668 1 0.84959 1 2p gain 13 (14%) 77 0.0073799 1 0.00142 0.949 0.59614 1 0.34033 1 0.01208 1 0.00025 0.173 0.37493 1 0.01907 1 0.1253 1 0.074129 1 2q gain 12 (13%) 78 0.052199 1 0.00249 1 0.42079 1 0.17586 1 0.01898 1 0.0026 1 0.056179 1 0.00489 1 0.02079 1 0.02428 1 3p gain 13 (14%) 77 0.2863 1 0.069049 1 0.45022 1 0.88279 1 0.33156 1 0.36497 1 0.40879 1 0.10928 1 0.63408 1 0.38771 1 3q gain 15 (17%) 75 0.39751 1 0.050789 1 0.89254 1 0.82224 1 0.052959 1 0.79247 1 0.65178 1 0.24579 1 0.67871 1 0.7113 1 4p gain 37 (41%) 53 9.9999e-06 0.00736 0.04437 1 1 1 0.46394 1 2e-05 0.0144 4e-05 0.0284 0.29697 1 0.00236 1 0.34303 1 0.8607 1 4q gain 33 (37%) 57 2e-05 0.0144 0.03672 1 0.92676 1 0.7293 1 3e-05 0.0214 2e-05 0.0144 0.55659 1 0.00079999 0.542 0.36071 1 0.94952 1 5p gain 57 (63%) 33 9.9999e-06 0.00736 0.03764 1 0.0459 1 0.03456 1 0.00050999 0.349 2e-05 0.0144 0.25201 1 0.22798 1 0.072359 1 0.35693 1 5q gain 53 (59%) 37 9.9999e-06 0.00736 0.0085099 1 0.41871 1 0.14781 1 0.00062999 0.428 9.9999e-06 0.00736 0.3363 1 0.13436 1 0.20911 1 0.16916 1 6p gain 18 (20%) 72 0.01713 1 0.68336 1 1 1 0.87591 1 0.066729 1 0.47198 1 0.16173 1 0.054959 1 0.41863 1 0.23618 1 6q gain 16 (18%) 74 0.073229 1 0.45768 1 0.60744 1 0.68497 1 0.20022 1 0.2932 1 0.29832 1 0.19652 1 0.15033 1 0.4358 1 7p gain 48 (53%) 42 5e-05 0.0355 0.11919 1 0.13904 1 0.092909 1 0.00011 0.077 0.00165 1 0.91506 1 0.55127 1 0.27846 1 0.28825 1 7q gain 48 (53%) 42 9.9999e-06 0.00736 0.11694 1 0.13921 1 0.24668 1 9.9999e-06 0.00736 7.9999e-05 0.0563 0.91544 1 0.32792 1 0.27739 1 0.19378 1 8p gain 32 (36%) 58 8.9999e-05 0.0632 0.14039 1 0.51718 1 0.4411 1 0.1698 1 0.14681 1 0.11224 1 0.17152 1 0.24156 1 0.51657 1 8q gain 38 (42%) 52 0.00022 0.152 0.29083 1 0.72263 1 0.46798 1 0.41765 1 0.22933 1 0.4992 1 0.25848 1 0.51984 1 0.6418 1 9p gain 20 (22%) 70 5.9999e-05 0.0425 0.00218 1 0.087789 1 0.13588 1 0.0090799 1 0.01179 1 0.38248 1 0.54886 1 0.46111 1 0.25169 1 9q gain 29 (32%) 61 0.00043 0.295 0.0011 0.737 0.03861 1 0.070309 1 0.02359 1 0.00206 1 0.03473 1 0.35327 1 0.089409 1 0.083089 1 10p gain 25 (28%) 65 0.0019 1 0.059719 1 0.01928 1 0.01369 1 6.9999e-05 0.0494 0.00014 0.0976 0.0343 1 0.50545 1 0.057269 1 0.4536 1 10q gain 26 (29%) 64 0.00147 0.979 0.071179 1 0.01721 1 0.01452 1 9.9999e-06 0.00736 0.00055999 0.381 0.02001 1 0.34279 1 0.03105 1 0.84428 1 11p gain 5 (6%) 85 0.091709 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 11q gain 6 (7%) 84 0.12565 1 0.17743 1 0.20067 1 0.4836 1 0.04439 1 0.079389 1 0.18605 1 0.36808 1 0.0054399 1 0.38974 1 12p gain 64 (71%) 26 9.9999e-06 0.00736 0.20862 1 0.20414 1 0.066769 1 0.00011 0.077 6.9999e-05 0.0494 0.24309 1 0.20917 1 0.13042 1 0.25019 1 12q gain 64 (71%) 26 9.9999e-06 0.00736 0.30771 1 0.15054 1 0.02796 1 0.00049 0.336 0.00021 0.146 0.23635 1 0.45454 1 0.22015 1 0.59116 1 13q gain 6 (7%) 84 0.4032 1 0.46349 1 0.49672 1 0.72429 1 0.03915 1 0.63419 1 0.14084 1 0.91627 1 0.18536 1 0.70041 1 14q gain 21 (23%) 69 0.01424 1 0.056079 1 0.10428 1 0.42664 1 0.00031 0.214 0.00105 0.706 9.9999e-06 0.00736 0.00017 0.118 3e-05 0.0214 2e-05 0.0144 15q gain 11 (12%) 79 0.094129 1 0.04727 1 0.44506 1 0.84531 1 0.01077 1 0.00472 1 0.35956 1 0.00069999 0.475 0.50587 1 0.25672 1 16p gain 49 (54%) 41 9.9999e-06 0.00736 0.01073 1 0.89424 1 0.04007 1 9.9999e-06 0.00736 9.9999e-06 0.00736 0.04639 1 0.02611 1 0.02845 1 0.27636 1 16q gain 47 (52%) 43 9.9999e-06 0.00736 0.0077799 1 0.95356 1 0.32654 1 7.9999e-05 0.0563 9.9999e-06 0.00736 0.02463 1 0.01287 1 0.01391 1 0.46199 1 17p gain 5 (6%) 85 0.11169 1 0.33566 1 NA NA NA NA 0.68582 1 0.14368 1 0.20763 1 0.79504 1 0.059489 1 0.062019 1 17q gain 7 (8%) 83 0.02491 1 0.33759 1 NA NA NA NA 0.68844 1 0.14206 1 0.20737 1 0.79416 1 0.059709 1 0.061729 1 18p gain 6 (7%) 84 0.26009 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 18q gain 5 (6%) 85 0.49284 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 19p gain 56 (62%) 34 0.00387 1 0.054639 1 0.061709 1 0.01905 1 0.00103 0.693 0.00050999 0.349 0.46593 1 0.47122 1 0.6394 1 0.22062 1 19q gain 52 (58%) 38 5e-05 0.0355 0.051769 1 0.29472 1 0.055779 1 0.00031 0.214 0.00096999 0.656 0.14264 1 0.1112 1 0.5171 1 0.11911 1 20p gain 46 (51%) 44 9.9999e-06 0.00736 0.23375 1 0.02277 1 0.0085099 1 0.00016 0.111 0.00011 0.077 0.00475 1 0.089269 1 0.0094999 1 0.00428 1 20q gain 49 (54%) 41 9.9999e-06 0.00736 0.066849 1 0.0098099 1 0.078019 1 5.9999e-05 0.0425 0.00029 0.2 0.01969 1 0.27689 1 0.01136 1 0.01457 1 21q gain 31 (34%) 59 0.02052 1 0.0090899 1 0.060039 1 0.23283 1 0.01995 1 0.00097999 0.661 0.0138 1 0.02002 1 0.00288 1 0.082889 1 22q gain 3 (3%) 87 0.63443 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA xq gain 40 (44%) 50 2e-05 0.0144 0.16533 1 0.28254 1 0.04306 1 0.00136 0.91 0.0086999 1 0.79646 1 0.15172 1 0.34277 1 0.13923 1 1p loss 29 (32%) 61 0.11735 1 0.14108 1 0.94902 1 0.12848 1 0.43828 1 0.064479 1 0.46677 1 0.41 1 0.02784 1 0.94802 1 1q loss 20 (22%) 70 0.20367 1 0.090409 1 0.51845 1 0.02566 1 0.96083 1 0.59729 1 0.37014 1 0.8414 1 0.078259 1 0.48975 1 2p loss 17 (19%) 73 0.0067599 1 0.02765 1 0.83553 1 0.65861 1 0.61541 1 0.26805 1 0.03852 1 0.76912 1 0.22849 1 0.699 1 2q loss 15 (17%) 75 0.00498 1 0.00109 0.731 0.73425 1 0.88457 1 0.11442 1 0.052479 1 0.03153 1 0.72786 1 0.069269 1 0.53656 1 3p loss 20 (22%) 70 0.25588 1 0.14173 1 0.2305 1 0.28979 1 0.11146 1 0.13655 1 0.5256 1 0.3879 1 0.68487 1 0.31551 1 3q loss 20 (22%) 70 0.16663 1 0.16471 1 0.53349 1 0.60267 1 0.02206 1 0.02989 1 0.19142 1 0.34065 1 0.31373 1 0.11675 1 4p loss 10 (11%) 80 0.095529 1 0.23292 1 1 1 0.98949 1 0.02374 1 0.081479 1 0.30696 1 0.93038 1 0.051309 1 1 1 4q loss 11 (12%) 79 0.23682 1 0.093459 1 0.8794 1 0.92341 1 0.0072999 1 0.02746 1 0.24788 1 0.81139 1 0.01299 1 0.90239 1 5p loss 8 (9%) 82 0.28664 1 0.052389 1 0.69487 1 0.19236 1 0.23066 1 0.01019 1 0.77417 1 0.2989 1 0.6954 1 1 1 5q loss 7 (8%) 83 0.89886 1 0.65432 1 NA NA NA NA 0.27555 1 0.13287 1 0.65797 1 0.12492 1 0.65956 1 0.84899 1 6p loss 19 (21%) 71 0.1455 1 0.85302 1 0.57339 1 0.23148 1 0.61965 1 0.69205 1 0.62724 1 0.099009 1 0.72612 1 0.52774 1 6q loss 22 (24%) 68 0.061519 1 0.85994 1 0.56848 1 0.27392 1 0.63299 1 0.69194 1 0.73102 1 0.17293 1 0.55773 1 0.32252 1 7p loss 5 (6%) 85 0.39142 1 0.58513 1 0.53202 1 0.20389 1 0.90928 1 0.8915 1 0.81568 1 0.41411 1 0.83233 1 0.11422 1 7q loss 6 (7%) 84 0.31551 1 0.30313 1 0.68506 1 0.77911 1 0.61849 1 0.65553 1 1 1 0.23563 1 0.73308 1 0.15034 1 8p loss 16 (18%) 74 0.0054599 1 0.22328 1 0.10378 1 0.00063999 0.435 0.18214 1 0.14113 1 0.18118 1 0.02312 1 0.2544 1 0.02966 1 8q loss 12 (13%) 78 0.00444 1 0.086599 1 0.40892 1 0.03592 1 0.03405 1 0.12275 1 0.076949 1 0.03569 1 0.17998 1 0.03783 1 9p loss 20 (22%) 70 0.00171 1 0.04803 1 0.55357 1 0.1166 1 9.9999e-05 0.0701 0.00099999 0.674 0.0090099 1 0.1389 1 0.00476 1 0.93757 1 9q loss 11 (12%) 79 0.32332 1 0.9359 1 1 1 0.03704 1 0.081179 1 0.32095 1 0.55712 1 0.49652 1 0.21427 1 0.80612 1 10p loss 12 (13%) 78 0.22267 1 0.42668 1 1 1 0.055489 1 0.26547 1 1 1 0.68246 1 0.7069 1 1 1 0.32598 1 10q loss 10 (11%) 80 0.53536 1 0.62485 1 1 1 0.23753 1 0.53305 1 1 1 1 1 0.70716 1 1 1 0.28811 1 11p loss 24 (27%) 66 0.0064399 1 0.0179 1 0.96483 1 0.79859 1 0.21832 1 0.18961 1 0.28053 1 0.89208 1 0.69023 1 1 1 11q loss 23 (26%) 67 0.01191 1 0.0029 1 0.83655 1 0.39577 1 0.13659 1 0.12786 1 0.10558 1 0.82611 1 0.49066 1 0.78054 1 12p loss 5 (6%) 85 0.090689 1 0.25227 1 0.25402 1 0.082579 1 0.62112 1 0.03807 1 0.10341 1 0.51867 1 0.43118 1 0.14948 1 12q loss 4 (4%) 86 0.18306 1 0.04784 1 0.25682 1 0.083709 1 0.44264 1 0.0093599 1 0.3322 1 0.23914 1 0.67489 1 0.11416 1 13q loss 39 (43%) 51 0.01443 1 0.082599 1 0.88452 1 0.94296 1 0.6255 1 0.88584 1 0.75167 1 0.30589 1 0.61379 1 0.49139 1 14q loss 18 (20%) 72 0.02752 1 0.44378 1 0.24876 1 0.053149 1 0.01817 1 0.04744 1 0.4085 1 0.53001 1 0.21475 1 0.14674 1 15q loss 21 (23%) 69 0.081769 1 0.41631 1 0.55405 1 0.51142 1 0.10961 1 0.22532 1 0.60566 1 0.04114 1 0.2888 1 0.87563 1 16p loss 6 (7%) 84 0.1249 1 0.04978 1 0.13817 1 0.04736 1 0.00215 1 0.00426 1 0.01325 1 0.44313 1 4e-04 0.275 0.46682 1 16q loss 5 (6%) 85 0.21503 1 0.077709 1 0.19609 1 0.17803 1 0.057969 1 0.084829 1 0.16833 1 0.30523 1 0.00145 0.967 0.70213 1 17p loss 32 (36%) 58 0.00305 1 0.00016 0.111 0.45603 1 0.19676 1 0.01156 1 0.0134 1 0.081129 1 0.00285 1 0.01424 1 0.11108 1 17q loss 24 (27%) 66 0.01485 1 0.0051299 1 0.63936 1 0.51553 1 0.11755 1 0.034 1 0.068629 1 0.02037 1 0.22846 1 0.10756 1 18p loss 37 (41%) 53 0.02384 1 0.25968 1 0.97632 1 0.68744 1 0.77358 1 0.64475 1 0.69521 1 0.69334 1 0.35347 1 0.34031 1 18q loss 35 (39%) 55 0.03642 1 0.42419 1 0.93296 1 0.53336 1 0.82455 1 0.93461 1 0.49547 1 0.9147 1 0.29174 1 0.35438 1 19p loss 5 (6%) 85 0.092289 1 0.44415 1 NA NA NA NA 0.15792 1 0.01332 1 0.14024 1 0.71795 1 0.27961 1 0.11074 1 19q loss 4 (4%) 86 0.18408 1 0.70631 1 NA NA NA NA 0.77097 1 0.11784 1 0.78425 1 0.20564 1 1 1 0.43169 1 20p loss 9 (10%) 81 0.04176 1 0.30341 1 0.54385 1 0.85398 1 0.21419 1 0.12318 1 0.067389 1 0.44701 1 0.02028 1 0.44418 1 20q loss 3 (3%) 87 0.17968 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 21q loss 15 (17%) 75 0.11374 1 0.33905 1 0.04985 1 0.052139 1 0.25426 1 0.25058 1 0.22576 1 0.50934 1 0.083589 1 0.10069 1 22q loss 48 (53%) 42 0.01534 1 0.080539 1 0.97428 1 0.48348 1 0.62051 1 0.28144 1 0.8758 1 0.82539 1 0.68208 1 0.22863 1 xq loss 17 (19%) 73 0.00054999 0.375 0.24369 1 0.26686 1 0.26379 1 0.03294 1 0.04563 1 0.65441 1 0.16778 1 0.24493 1 0.79776 1