Correlation between gene mutation status and molecular subtypes

Adrenocortical Carcinoma (Primary solid tumor)

17 October 2014 | analyses__2014_10_17

Maintainer Information

Citation Information

Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)

Cite as Broad Institute TCGA Genome Data Analysis Center (2014): Correlation between gene mutation status and molecular subtypes. Broad Institute of MIT and Harvard. doi:10.7908/C1ZG6R2V

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 119 genes and 10 molecular subtypes across 62 patients, no significant finding detected with P value < 0.05 and Q value < 0.25.

No gene mutations related to molecuar subtypes.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 119 genes and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, no significant finding detected.


		Clinical Features	CN CNMF	METHLYATION CNMF	RPPA CNMF	RPPA CHIERARCHICAL	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
ZFPM1	24 (39%)	38	0.801 (1.00)	0.816 (1.00)	0.716 (1.00)	0.872 (1.00)	0.375 (1.00)	0.745 (1.00)	0.822 (1.00)	0.923 (1.00)	0.382 (1.00)	0.742 (1.00)
LACTB	19 (31%)	43	0.436 (1.00)	0.691 (1.00)	0.66 (1.00)	0.566 (1.00)	1 (1.00)	0.316 (1.00)	0.378 (1.00)	0.752 (1.00)	0.32 (1.00)	0.178 (1.00)
CCDC102A	17 (27%)	45	0.019 (1.00)	0.936 (1.00)	0.88 (1.00)	0.507 (1.00)	0.975 (1.00)	0.826 (1.00)	0.497 (1.00)	0.469 (1.00)	0.805 (1.00)	0.507 (1.00)
ZNF517	13 (21%)	49	0.166 (1.00)	0.98 (1.00)			0.82 (1.00)	0.951 (1.00)	0.173 (1.00)	0.698 (1.00)	0.726 (1.00)	0.773 (1.00)
MAL2	11 (18%)	51	0.499 (1.00)	0.313 (1.00)	0.209 (1.00)	1 (1.00)	0.253 (1.00)	0.509 (1.00)	0.218 (1.00)	0.268 (1.00)	1 (1.00)	0.867 (1.00)
CLDN23	10 (16%)	52	0.572 (1.00)	0.249 (1.00)	1 (1.00)	0.349 (1.00)	0.0297 (1.00)	0.211 (1.00)	0.0984 (1.00)	0.182 (1.00)	0.416 (1.00)	0.542 (1.00)
TOR3A	12 (19%)	50	0.61 (1.00)	0.0136 (1.00)	0.138 (1.00)	0.315 (1.00)	0.679 (1.00)	0.005 (1.00)	1 (1.00)	0.844 (1.00)	0.912 (1.00)	0.808 (1.00)
USP42	15 (24%)	47	0.549 (1.00)	0.0469 (1.00)	1 (1.00)	0.466 (1.00)	1 (1.00)	0.96 (1.00)	0.457 (1.00)	0.873 (1.00)	0.911 (1.00)	0.903 (1.00)
TP53	12 (19%)	50	0.133 (1.00)	0.793 (1.00)	0.068 (1.00)	0.466 (1.00)	0.0201 (1.00)	0.667 (1.00)	0.0158 (1.00)	0.672 (1.00)	0.00614 (1.00)	0.178 (1.00)
APOE	7 (11%)	55	1 (1.00)	0.593 (1.00)	0.589 (1.00)	0.384 (1.00)	0.0602 (1.00)	0.401 (1.00)	0.195 (1.00)	0.791 (1.00)	0.416 (1.00)	1 (1.00)
ZAR1	11 (18%)	51	0.645 (1.00)	0.67 (1.00)	0.209 (1.00)	0.793 (1.00)	0.624 (1.00)	0.869 (1.00)	0.716 (1.00)	0.972 (1.00)	1 (1.00)	0.603 (1.00)
ASPDH	8 (13%)	54	0.301 (1.00)	0.688 (1.00)	0.717 (1.00)	0.314 (1.00)	0.0236 (1.00)	0.398 (1.00)	0.474 (1.00)	0.031 (1.00)	0.213 (1.00)	0.081 (1.00)
KCNK17	9 (15%)	53	0.201 (1.00)	0.0391 (1.00)	0.179 (1.00)	0.439 (1.00)	0.104 (1.00)	0.00942 (1.00)	0.891 (1.00)	0.548 (1.00)	0.717 (1.00)	0.444 (1.00)
LZTR1	6 (10%)	56	0.0517 (1.00)	0.851 (1.00)			0.0896 (1.00)	0.12 (1.00)	0.401 (1.00)	0.0143 (1.00)	1 (1.00)	0.453 (1.00)
ERCC2	10 (16%)	52	1 (1.00)	0.232 (1.00)	0.218 (1.00)	0.233 (1.00)	0.482 (1.00)	0.172 (1.00)	0.597 (1.00)	0.268 (1.00)	0.337 (1.00)	0.207 (1.00)
RINL	8 (13%)	54	0.339 (1.00)	0.678 (1.00)	0.528 (1.00)	0.579 (1.00)	0.464 (1.00)	0.273 (1.00)	0.76 (1.00)	0.169 (1.00)	0.345 (1.00)	0.748 (1.00)
SYT8	8 (13%)	54	0.443 (1.00)	0.441 (1.00)	1 (1.00)	1 (1.00)	0.0415 (1.00)	0.177 (1.00)	1 (1.00)	0.185 (1.00)	0.751 (1.00)	0.496 (1.00)
LRIG1	16 (26%)	46	0.542 (1.00)	0.96 (1.00)	0.211 (1.00)	1 (1.00)	0.865 (1.00)	0.611 (1.00)	0.362 (1.00)	0.435 (1.00)	0.577 (1.00)	0.902 (1.00)
C1ORF106	9 (15%)	53	0.843 (1.00)	0.471 (1.00)	0.164 (1.00)	0.0475 (1.00)	0.34 (1.00)	0.761 (1.00)	0.474 (1.00)	0.693 (1.00)	0.053 (1.00)	1 (1.00)
GPRIN2	8 (13%)	54	0.867 (1.00)	0.381 (1.00)	0.21 (1.00)	0.693 (1.00)	0.682 (1.00)	0.402 (1.00)	0.578 (1.00)	0.754 (1.00)	0.594 (1.00)	0.183 (1.00)
CTNNB1	7 (11%)	55	0.731 (1.00)	0.185 (1.00)	0.211 (1.00)	0.395 (1.00)	0.0176 (1.00)	0.0235 (1.00)	0.00079 (0.767)	0.175 (1.00)	0.125 (1.00)	0.713 (1.00)
C16ORF3	5 (8%)	57	0.858 (1.00)	0.00076 (0.739)	0.59 (1.00)	0.788 (1.00)	0.8 (1.00)	0.815 (1.00)	0.582 (1.00)	1 (1.00)	0.726 (1.00)	0.835 (1.00)
CCDC105	6 (10%)	56	1 (1.00)	0.0109 (1.00)	0.588 (1.00)	0.676 (1.00)	0.938 (1.00)	0.795 (1.00)	1 (1.00)	0.0535 (1.00)	0.217 (1.00)	0.208 (1.00)
RGS9BP	8 (13%)	54	0.727 (1.00)	0.632 (1.00)	1 (1.00)	0.128 (1.00)	1 (1.00)	0.934 (1.00)	0.218 (1.00)	0.962 (1.00)	0.343 (1.00)	0.754 (1.00)
HHIPL1	6 (10%)	56	0.276 (1.00)	0.434 (1.00)			0.631 (1.00)	0.513 (1.00)	0.207 (1.00)	0.422 (1.00)	0.201 (1.00)	0.333 (1.00)
C10ORF95	6 (10%)	56	0.199 (1.00)	0.378 (1.00)			0.513 (1.00)	1 (1.00)	0.485 (1.00)	0.356 (1.00)	1 (1.00)	1 (1.00)
TSC22D2	8 (13%)	54	0.947 (1.00)	0.541 (1.00)	0.767 (1.00)	0.954 (1.00)	0.78 (1.00)	0.817 (1.00)	0.761 (1.00)	0.429 (1.00)	0.35 (1.00)	1 (1.00)
NOXA1	5 (8%)	57	0.145 (1.00)	0.514 (1.00)			0.222 (1.00)	0.442 (1.00)	0.293 (1.00)	0.353 (1.00)	0.252 (1.00)	0.722 (1.00)
THEM4	5 (8%)	57	0.281 (1.00)	0.769 (1.00)			0.44 (1.00)	0.876 (1.00)	0.179 (1.00)	0.107 (1.00)	0.232 (1.00)	0.261 (1.00)
ATXN1	10 (16%)	52	0.556 (1.00)	0.139 (1.00)	0.887 (1.00)	0.915 (1.00)	0.236 (1.00)	0.658 (1.00)	0.285 (1.00)	0.871 (1.00)	0.235 (1.00)	0.315 (1.00)
PLIN5	5 (8%)	57	0.499 (1.00)	0.696 (1.00)	0.454 (1.00)	0.385 (1.00)	0.8 (1.00)	0.667 (1.00)	0.268 (1.00)	0.265 (1.00)	0.511 (1.00)	0.0465 (1.00)
OPRD1	12 (19%)	50	0.968 (1.00)	0.434 (1.00)	0.28 (1.00)	0.478 (1.00)	0.799 (1.00)	0.96 (1.00)	0.3 (1.00)	0.614 (1.00)	1 (1.00)	0.51 (1.00)
KRTAP4-5	5 (8%)	57	0.632 (1.00)	0.286 (1.00)			0.909 (1.00)	0.876 (1.00)	1 (1.00)	0.843 (1.00)	0.435 (1.00)	1 (1.00)
C19ORF10	7 (11%)	55	0.782 (1.00)	0.423 (1.00)	0.887 (1.00)	0.39 (1.00)	0.241 (1.00)	0.124 (1.00)	0.551 (1.00)	0.862 (1.00)	0.638 (1.00)	0.715 (1.00)
AATK	6 (10%)	56	0.139 (1.00)	0.331 (1.00)			0.441 (1.00)	0.356 (1.00)	1 (1.00)	0.544 (1.00)	1 (1.00)	0.62 (1.00)
SARM1	6 (10%)	56	0.208 (1.00)	0.422 (1.00)	0.886 (1.00)	0.694 (1.00)	0.174 (1.00)	0.114 (1.00)	0.266 (1.00)	0.836 (1.00)	0.512 (1.00)	0.0793 (1.00)
TRIOBP	10 (16%)	52	0.62 (1.00)	0.229 (1.00)	0.453 (1.00)	0.128 (1.00)	1 (1.00)	0.112 (1.00)	0.713 (1.00)	0.871 (1.00)	1 (1.00)	0.774 (1.00)
ZNF598	12 (19%)	50	0.111 (1.00)	0.316 (1.00)	0.427 (1.00)	0.75 (1.00)	0.489 (1.00)	0.953 (1.00)	1 (1.00)	0.226 (1.00)	0.901 (1.00)	1 (1.00)
WDR34	5 (8%)	57	0.633 (1.00)	0.831 (1.00)			0.863 (1.00)	0.815 (1.00)	0.842 (1.00)	0.551 (1.00)	0.842 (1.00)	0.336 (1.00)
ZNF628	7 (11%)	55	0.21 (1.00)	0.927 (1.00)	0.591 (1.00)	0.675 (1.00)	0.313 (1.00)	0.117 (1.00)	0.0947 (1.00)	0.503 (1.00)	0.286 (1.00)	0.545 (1.00)
BTBD11	6 (10%)	56	1 (1.00)	0.315 (1.00)			0.484 (1.00)	1 (1.00)	0.488 (1.00)	0.183 (1.00)	0.726 (1.00)	0.33 (1.00)
IRX3	5 (8%)	57	0.141 (1.00)	0.707 (1.00)			0.522 (1.00)	0.12 (1.00)	0.179 (1.00)	0.779 (1.00)	0.231 (1.00)	0.453 (1.00)
FPGS	5 (8%)	57	1 (1.00)	1 (1.00)	0.452 (1.00)	0.351 (1.00)	0.665 (1.00)	0.601 (1.00)	0.0553 (1.00)	0.627 (1.00)	0.822 (1.00)	0.62 (1.00)
MEN1	5 (8%)	57	0.418 (1.00)	0.0487 (1.00)			0.0131 (1.00)	0.00683 (1.00)	0.206 (1.00)	0.0426 (1.00)	0.136 (1.00)	0.201 (1.00)
BHLHE22	5 (8%)	57	0.425 (1.00)	0.0719 (1.00)	0.889 (1.00)	0.916 (1.00)	0.12 (1.00)	0.817 (1.00)	0.582 (1.00)	0.836 (1.00)	0.727 (1.00)	0.836 (1.00)
DMKN	3 (5%)	59	1 (1.00)	0.325 (1.00)			0.617 (1.00)	0.441 (1.00)	0.00622 (1.00)	0.568 (1.00)	0.254 (1.00)	1 (1.00)
OBSCN	18 (29%)	44	0.31 (1.00)	0.52 (1.00)	1 (1.00)	0.545 (1.00)	0.672 (1.00)	0.807 (1.00)	0.148 (1.00)	0.498 (1.00)	1 (1.00)	0.386 (1.00)
PANK2	5 (8%)	57	0.628 (1.00)	0.431 (1.00)	0.451 (1.00)	0.348 (1.00)	0.115 (1.00)	0.052 (1.00)	0.429 (1.00)	0.35 (1.00)	1 (1.00)	0.255 (1.00)
RREB1	5 (8%)	57	0.727 (1.00)	0.851 (1.00)			0.619 (1.00)	1 (1.00)	0.528 (1.00)	0.547 (1.00)	0.174 (1.00)	0.352 (1.00)
RNF149	4 (6%)	58	0.339 (1.00)	0.0367 (1.00)	0.766 (1.00)	0.954 (1.00)	0.437 (1.00)	0.6 (1.00)	0.318 (1.00)	0.259 (1.00)	0.663 (1.00)	0.174 (1.00)
GLTPD2	6 (10%)	56	0.877 (1.00)	0.842 (1.00)			0.829 (1.00)	0.399 (1.00)	0.551 (1.00)	0.531 (1.00)	0.873 (1.00)	0.132 (1.00)
SNED1	5 (8%)	57	0.629 (1.00)	0.314 (1.00)			0.4 (1.00)	0.666 (1.00)	0.0943 (1.00)	0.662 (1.00)	1 (1.00)	0.544 (1.00)
TPO	12 (19%)	50	0.262 (1.00)	0.303 (1.00)	0.887 (1.00)	0.697 (1.00)	0.174 (1.00)	0.125 (1.00)	0.0981 (1.00)	0.341 (1.00)	1 (1.00)	0.17 (1.00)
PTPLA	4 (6%)	58	0.418 (1.00)	0.325 (1.00)			0.336 (1.00)	0.443 (1.00)	0.776 (1.00)	1 (1.00)	0.774 (1.00)	1 (1.00)
PRSS27	3 (5%)	59	1 (1.00)	0.91 (1.00)			0.619 (1.00)	0.0506 (1.00)	0.131 (1.00)	1 (1.00)	0.614 (1.00)	0.557 (1.00)
CD320	4 (6%)	58	1 (1.00)	0.853 (1.00)			0.738 (1.00)	0.659 (1.00)	0.4 (1.00)	0.225 (1.00)	0.232 (1.00)	0.261 (1.00)
SEMA5B	8 (13%)	54	0.342 (1.00)	0.269 (1.00)	0.624 (1.00)	0.174 (1.00)	0.397 (1.00)	0.215 (1.00)	0.65 (1.00)	0.299 (1.00)	0.362 (1.00)	0.408 (1.00)
CCDC150	4 (6%)	58	0.18 (1.00)	0.851 (1.00)	1 (1.00)	0.601 (1.00)	0.238 (1.00)	0.117 (1.00)	0.4 (1.00)	0.209 (1.00)	1 (1.00)	0.454 (1.00)
TAF5	4 (6%)	58	1 (1.00)	0.769 (1.00)	1 (1.00)	0.953 (1.00)	1 (1.00)	0.877 (1.00)	0.00926 (1.00)	0.115 (1.00)	0.0555 (1.00)	0.0141 (1.00)
GARS	19 (31%)	43	0.0754 (1.00)	0.0922 (1.00)	0.381 (1.00)	0.335 (1.00)	0.341 (1.00)	0.102 (1.00)	0.118 (1.00)	0.402 (1.00)	0.214 (1.00)	0.399 (1.00)
MUC5B	22 (35%)	40	1 (1.00)	0.631 (1.00)	0.53 (1.00)	0.809 (1.00)	0.733 (1.00)	0.67 (1.00)	0.715 (1.00)	0.617 (1.00)	1 (1.00)	0.531 (1.00)
KIAA1984	4 (6%)	58	0.418 (1.00)	0.709 (1.00)	0.451 (1.00)	0.505 (1.00)	0.127 (1.00)	0.0493 (1.00)	0.0313 (1.00)	0.581 (1.00)	0.665 (1.00)	0.793 (1.00)
SRPX	3 (5%)	59	0.753 (1.00)	0.112 (1.00)			0.618 (1.00)	1 (1.00)	0.776 (1.00)	0.718 (1.00)	1 (1.00)	0.401 (1.00)
TNIP2	5 (8%)	57	0.629 (1.00)	0.708 (1.00)			0.739 (1.00)	0.876 (1.00)	1 (1.00)	0.414 (1.00)	1 (1.00)	0.453 (1.00)
IDUA	8 (13%)	54	0.381 (1.00)	0.854 (1.00)	0.528 (1.00)	0.794 (1.00)	0.508 (1.00)	0.546 (1.00)	0.202 (1.00)	0.432 (1.00)	0.457 (1.00)	0.645 (1.00)
RNF39	5 (8%)	57	0.726 (1.00)	0.38 (1.00)	0.253 (1.00)	0.794 (1.00)	0.176 (1.00)	0.266 (1.00)	0.158 (1.00)	0.698 (1.00)	0.239 (1.00)	0.686 (1.00)
PABPC1	4 (6%)	58	0.417 (1.00)
SCRT1	3 (5%)	59	1 (1.00)	0.43 (1.00)			0.474 (1.00)	0.616 (1.00)	0.426 (1.00)	0.795 (1.00)	0.468 (1.00)	1 (1.00)
MAP1S	5 (8%)	57	0.158 (1.00)	0.277 (1.00)	0.21 (1.00)	0.42 (1.00)	0.401 (1.00)	1 (1.00)	1 (1.00)	0.835 (1.00)	0.42 (1.00)	0.837 (1.00)
NF1	7 (11%)	55	0.251 (1.00)	0.903 (1.00)	0.889 (1.00)	0.392 (1.00)	0.359 (1.00)	0.192 (1.00)	0.282 (1.00)	0.885 (1.00)	1 (1.00)	0.0966 (1.00)
AKAP2	4 (6%)	58	0.106 (1.00)	0.435 (1.00)	0.454 (1.00)	0.676 (1.00)	0.74 (1.00)	0.172 (1.00)	0.527 (1.00)	0.446 (1.00)	0.824 (1.00)	0.349 (1.00)
NOTCH2	5 (8%)	57	0.279 (1.00)	0.895 (1.00)			0.524 (1.00)	0.118 (1.00)	0.031 (1.00)	0.318 (1.00)	0.665 (1.00)	0.795 (1.00)
FANK1	4 (6%)	58	1 (1.00)	0.323 (1.00)			0.857 (1.00)	0.289 (1.00)	0.777 (1.00)	0.235 (1.00)	0.774 (1.00)	0.254 (1.00)
NEFH	6 (10%)	56	0.0523 (1.00)	0.175 (1.00)			0.116 (1.00)	0.0509 (1.00)	0.399 (1.00)	0.21 (1.00)	0.663 (1.00)	0.452 (1.00)
NPTX1	3 (5%)	59	0.638 (1.00)	1 (1.00)			1 (1.00)	0.817 (1.00)	0.581 (1.00)	0.794 (1.00)	0.352 (1.00)	0.558 (1.00)
KBTBD13	9 (15%)	53	0.457 (1.00)	0.117 (1.00)	1 (1.00)	0.791 (1.00)	0.686 (1.00)	0.115 (1.00)	1 (1.00)	0.329 (1.00)	1 (1.00)	0.605 (1.00)
RASIP1	6 (10%)	56	0.361 (1.00)	0.35 (1.00)			0.0403 (1.00)	0.188 (1.00)	0.0558 (1.00)	0.7 (1.00)	0.417 (1.00)	0.712 (1.00)
AR	4 (6%)	58	0.416 (1.00)	0.516 (1.00)	1 (1.00)	0.954 (1.00)	0.474 (1.00)	0.447 (1.00)	0.43 (1.00)	1 (1.00)	0.254 (1.00)	1 (1.00)
KNDC1	9 (15%)	53	0.353 (1.00)	0.0666 (1.00)	0.452 (1.00)	0.553 (1.00)	0.0255 (1.00)	0.328 (1.00)	0.421 (1.00)	0.365 (1.00)	0.187 (1.00)	0.385 (1.00)
SEZ6L2	8 (13%)	54	0.381 (1.00)	0.667 (1.00)	0.451 (1.00)	0.791 (1.00)	0.829 (1.00)	1 (1.00)	0.465 (1.00)	0.628 (1.00)	1 (1.00)	0.852 (1.00)
VARS	6 (10%)	56	1 (1.00)	0.422 (1.00)	0.453 (1.00)	0.386 (1.00)	0.216 (1.00)	0.066 (1.00)	0.646 (1.00)	0.862 (1.00)	0.75 (1.00)	1 (1.00)
IER5	3 (5%)	59	0.2 (1.00)
NMU	5 (8%)	57	0.915 (1.00)	1 (1.00)			0.0691 (1.00)	0.613 (1.00)	1 (1.00)	0.546 (1.00)	0.823 (1.00)	0.621 (1.00)
TMEM189	3 (5%)	59	0.2 (1.00)
ADAD2	4 (6%)	58	0.419 (1.00)	0.575 (1.00)			0.738 (1.00)	0.173 (1.00)	0.00966 (1.00)	0.512 (1.00)	0.0568 (1.00)	0.352 (1.00)
PLEC	13 (21%)	49	0.428 (1.00)	0.671 (1.00)	0.197 (1.00)	0.0486 (1.00)	0.204 (1.00)	0.719 (1.00)	0.596 (1.00)	0.633 (1.00)	0.14 (1.00)	0.625 (1.00)
RGMB	6 (10%)	56	0.651 (1.00)
CLIC6	5 (8%)	57	0.631 (1.00)	1 (1.00)			0.665 (1.00)	0.118 (1.00)	0.178 (1.00)	0.583 (1.00)	0.294 (1.00)	1 (1.00)
ZNF814	3 (5%)	59	1 (1.00)
DSPP	9 (15%)	53	0.61 (1.00)	0.0597 (1.00)	0.888 (1.00)	0.693 (1.00)	1 (1.00)	0.484 (1.00)	0.446 (1.00)	0.54 (1.00)	0.901 (1.00)	1 (1.00)
AMDHD1	10 (16%)	52	0.655 (1.00)	0.758 (1.00)	1 (1.00)	0.351 (1.00)	0.588 (1.00)	0.138 (1.00)	0.173 (1.00)	0.852 (1.00)	0.901 (1.00)	0.683 (1.00)
CRIPAK	10 (16%)	52	0.385 (1.00)	0.929 (1.00)	0.887 (1.00)	0.935 (1.00)	0.49 (1.00)	0.687 (1.00)	0.895 (1.00)	0.33 (1.00)	0.477 (1.00)	0.364 (1.00)
NOM1	6 (10%)	56	1 (1.00)	0.314 (1.00)			0.865 (1.00)	1 (1.00)	1 (1.00)	0.788 (1.00)	0.422 (1.00)	1 (1.00)
MAP7	3 (5%)	59	1 (1.00)	0.653 (1.00)			1 (1.00)	0.813 (1.00)	0.581 (1.00)	0.793 (1.00)	1 (1.00)	0.553 (1.00)
PTX4	3 (5%)	59	1 (1.00)	1 (1.00)			0.472 (1.00)	0.195 (1.00)	0.43 (1.00)	1 (1.00)	0.253 (1.00)	0.255 (1.00)
LRP11	6 (10%)	56	1 (1.00)	0.0797 (1.00)			0.8 (1.00)	0.664 (1.00)	0.581 (1.00)	0.936 (1.00)	0.842 (1.00)	0.838 (1.00)
PDCD6	3 (5%)	59	0.299 (1.00)	0.651 (1.00)					1 (1.00)	0.641 (1.00)	1 (1.00)	1 (1.00)
SHOX2	3 (5%)	59	0.413 (1.00)
UQCRFS1	5 (8%)	57	0.75 (1.00)	0.587 (1.00)			1 (1.00)	0.876 (1.00)	0.489 (1.00)	0.202 (1.00)	0.843 (1.00)	0.334 (1.00)
CTBP2	3 (5%)	59	0.754 (1.00)
PRKAR1A	6 (10%)	56	0.618 (1.00)	1 (1.00)	0.886 (1.00)	0.793 (1.00)	0.278 (1.00)	0.403 (1.00)	0.105 (1.00)	0.586 (1.00)	0.0493 (1.00)	0.588 (1.00)
JMJD4	3 (5%)	59	1 (1.00)
HSD17B1	4 (6%)	58	0.914 (1.00)	0.0479 (1.00)	0.765 (1.00)	0.508 (1.00)	0.91 (1.00)	0.0082 (1.00)	1 (1.00)	0.843 (1.00)	0.549 (1.00)	0.796 (1.00)
COQ2	5 (8%)	57	0.361 (1.00)	0.768 (1.00)			0.438 (1.00)	0.599 (1.00)	1 (1.00)	0.673 (1.00)	0.547 (1.00)	0.617 (1.00)
FEZ2	3 (5%)	59	0.467 (1.00)	0.354 (1.00)			0.222 (1.00)	0.814 (1.00)	0.196 (1.00)	0.795 (1.00)	0.776 (1.00)	0.556 (1.00)
DLEU7	3 (5%)	59	0.528 (1.00)
RNF135	3 (5%)	59	0.756 (1.00)
SPIRE2	3 (5%)	59	0.3 (1.00)	0.0386 (1.00)			1 (1.00)	0.814 (1.00)	1 (1.00)	0.795 (1.00)	1 (1.00)	1 (1.00)
KRTAP5-5	3 (5%)	59	1 (1.00)
SGK223	3 (5%)	59	0.754 (1.00)
C9ORF66	5 (8%)	57	1 (1.00)	0.925 (1.00)			1 (1.00)	0.512 (1.00)	0.581 (1.00)	0.936 (1.00)	0.35 (1.00)	0.541 (1.00)
AQP7	3 (5%)	59	0.755 (1.00)
ADAMTS7	4 (6%)	58	0.197 (1.00)	0.477 (1.00)	0.0124 (1.00)	0.35 (1.00)	0.0905 (1.00)	0.438 (1.00)	0.0824 (1.00)	0.258 (1.00)	0.124 (1.00)	0.0387 (1.00)
PCDHB13	5 (8%)	57	0.395 (1.00)	0.141 (1.00)			0.127 (1.00)	0.356 (1.00)	0.663 (1.00)	0.0596 (1.00)	0.436 (1.00)	0.453 (1.00)
CSGALNACT2	3 (5%)	59	0.161 (1.00)	0.0388 (1.00)			0.774 (1.00)	0.812 (1.00)	0.583 (1.00)	0.876 (1.00)	0.352 (1.00)	0.401 (1.00)
HLA-A	3 (5%)	59	1 (1.00)	1 (1.00)			0.852 (1.00)	0.194 (1.00)	1 (1.00)	0.506 (1.00)	0.775 (1.00)	0.254 (1.00)
MTFMT	3 (5%)	59	1 (1.00)
NLRP5	4 (6%)	58	0.914 (1.00)	0.171 (1.00)			1 (1.00)	0.121 (1.00)	0.778 (1.00)	0.643 (1.00)	1 (1.00)	0.076 (1.00)
KCNJ11	4 (6%)	58	0.0191 (1.00)	0.709 (1.00)			0.436 (1.00)	0.23 (1.00)	0.126 (1.00)	0.0534 (1.00)	0.291 (1.00)	0.259 (1.00)

'ZFPM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S1. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZFPM1 MUTATED	10	8	3	3
ZFPM1 WILD-TYPE	11	12	7	6

'ZFPM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S2. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZFPM1 MUTATED	6	4	4	5	2
ZFPM1 WILD-TYPE	7	4	10	8	5

'ZFPM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.716 (Fisher's exact test), Q value = 1

Table S3. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
ZFPM1 MUTATED	3	5	2	2
ZFPM1 WILD-TYPE	5	3	4	4

'ZFPM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S4. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZFPM1 MUTATED	2	4	1	1	1	1	1	1
ZFPM1 WILD-TYPE	3	2	4	2	2	0	2	1

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S5. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZFPM1 MUTATED	7	1	7	6
ZFPM1 WILD-TYPE	9	7	7	10

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S6. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZFPM1 MUTATED	8	6	1	6
ZFPM1 WILD-TYPE	8	10	3	12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S7. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZFPM1 MUTATED	10	5	6
ZFPM1 WILD-TYPE	16	6	12

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S8. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZFPM1 MUTATED	5	8	2	5	1
ZFPM1 WILD-TYPE	8	10	6	9	1

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S9. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZFPM1 MUTATED	9	7	5
ZFPM1 WILD-TYPE	12	7	14

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S10. Gene #1: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZFPM1 MUTATED	12	7	2
ZFPM1 WILD-TYPE	18	9	6

'LACTB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S11. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
LACTB MUTATED	6	5	3	5
LACTB WILD-TYPE	15	15	7	4

'LACTB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S12. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
LACTB MUTATED	2	3	5	4	3
LACTB WILD-TYPE	11	5	9	9	4

'LACTB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S13. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
LACTB MUTATED	2	2	1	3
LACTB WILD-TYPE	6	6	5	3

'LACTB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.566 (Fisher's exact test), Q value = 1

Table S14. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
LACTB MUTATED	2	1	2	0	2	0	0	1
LACTB WILD-TYPE	3	5	3	3	1	1	3	1

'LACTB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S15. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
LACTB MUTATED	5	2	5	5
LACTB WILD-TYPE	11	6	9	11

'LACTB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S16. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LACTB MUTATED	4	5	3	5
LACTB WILD-TYPE	12	11	1	13

'LACTB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.378 (Fisher's exact test), Q value = 1

Table S17. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
LACTB MUTATED	6	5	6
LACTB WILD-TYPE	20	6	12

'LACTB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S18. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LACTB MUTATED	4	5	4	4	0
LACTB WILD-TYPE	9	13	4	10	2

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 1

Table S19. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
LACTB MUTATED	8	2	7
LACTB WILD-TYPE	13	12	12

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S20. Gene #2: 'LACTB MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
LACTB MUTATED	8	4	5
LACTB WILD-TYPE	22	12	3

'CCDC102A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.019 (Fisher's exact test), Q value = 1

Table S21. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CCDC102A MUTATED	4	8	0	5
CCDC102A WILD-TYPE	17	12	10	4

Figure S1. Get High-res Image Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'CCDC102A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S22. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CCDC102A MUTATED	3	2	4	4	3
CCDC102A WILD-TYPE	10	6	10	9	4

'CCDC102A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S23. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
CCDC102A MUTATED	2	3	1	1
CCDC102A WILD-TYPE	6	5	5	5

'CCDC102A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S24. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CCDC102A MUTATED	1	1	0	1	1	1	1	1
CCDC102A WILD-TYPE	4	5	5	2	2	0	2	1

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.975 (Fisher's exact test), Q value = 1

Table S25. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CCDC102A MUTATED	4	3	4	5
CCDC102A WILD-TYPE	12	5	10	11

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S26. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CCDC102A MUTATED	4	4	1	7
CCDC102A WILD-TYPE	12	12	3	11

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S27. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CCDC102A MUTATED	7	2	7
CCDC102A WILD-TYPE	19	9	11

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S28. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CCDC102A MUTATED	2	6	4	4	0
CCDC102A WILD-TYPE	11	12	4	10	2

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S29. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CCDC102A MUTATED	7	3	6
CCDC102A WILD-TYPE	14	11	13

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S30. Gene #3: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CCDC102A MUTATED	7	6	3
CCDC102A WILD-TYPE	23	10	5

'ZNF517 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 1

Table S31. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZNF517 MUTATED	7	5	0	1
ZNF517 WILD-TYPE	14	15	10	8

'ZNF517 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.98 (Fisher's exact test), Q value = 1

Table S32. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZNF517 MUTATED	3	1	2	2	1
ZNF517 WILD-TYPE	10	7	12	11	6

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S33. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZNF517 MUTATED	4	1	2	2
ZNF517 WILD-TYPE	12	7	12	14

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.951 (Fisher's exact test), Q value = 1

Table S34. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZNF517 MUTATED	3	2	1	3
ZNF517 WILD-TYPE	13	14	3	15

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S35. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZNF517 MUTATED	3	4	2
ZNF517 WILD-TYPE	23	7	16

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S36. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZNF517 MUTATED	1	3	1	4	0
ZNF517 WILD-TYPE	12	15	7	10	2

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S37. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZNF517 MUTATED	4	3	2
ZNF517 WILD-TYPE	17	11	17

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S38. Gene #4: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZNF517 MUTATED	5	2	2
ZNF517 WILD-TYPE	25	14	6

'MAL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S39. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MAL2 MUTATED	4	5	2	0
MAL2 WILD-TYPE	17	15	8	9

'MAL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S40. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MAL2 MUTATED	3	2	0	2	1
MAL2 WILD-TYPE	10	6	14	11	6

'MAL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S41. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
MAL2 MUTATED	2	0	0	2
MAL2 WILD-TYPE	6	8	6	4

'MAL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S42. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
MAL2 MUTATED	1	1	1	1	0	0	0	0
MAL2 WILD-TYPE	4	5	4	2	3	1	3	2

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 1

Table S43. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MAL2 MUTATED	3	2	0	3
MAL2 WILD-TYPE	13	6	14	13

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S44. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MAL2 MUTATED	4	1	0	3
MAL2 WILD-TYPE	12	15	4	15

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 1

Table S45. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MAL2 MUTATED	2	3	3
MAL2 WILD-TYPE	24	8	15

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S46. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MAL2 MUTATED	0	3	1	4	0
MAL2 WILD-TYPE	13	15	7	10	2

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S47. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MAL2 MUTATED	3	2	3
MAL2 WILD-TYPE	18	12	16

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.867 (Fisher's exact test), Q value = 1

Table S48. Gene #5: 'MAL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MAL2 MUTATED	4	3	1
MAL2 WILD-TYPE	26	13	7

'CLDN23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.572 (Fisher's exact test), Q value = 1

Table S49. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CLDN23 MUTATED	2	5	1	2
CLDN23 WILD-TYPE	19	15	9	7

'CLDN23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S50. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CLDN23 MUTATED	1	2	1	3	3
CLDN23 WILD-TYPE	12	6	13	10	4

'CLDN23 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S51. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
CLDN23 MUTATED	1	1	0	1
CLDN23 WILD-TYPE	7	7	6	5

'CLDN23 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S52. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CLDN23 MUTATED	1	0	0	0	1	0	0	1
CLDN23 WILD-TYPE	4	6	5	3	2	1	3	1

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0297 (Fisher's exact test), Q value = 1

Table S53. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CLDN23 MUTATED	1	1	1	7
CLDN23 WILD-TYPE	15	7	13	9

Figure S2. Get High-res Image Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S54. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CLDN23 MUTATED	3	1	0	6
CLDN23 WILD-TYPE	13	15	4	12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0984 (Fisher's exact test), Q value = 1

Table S55. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CLDN23 MUTATED	2	2	6
CLDN23 WILD-TYPE	24	9	12

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S56. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CLDN23 MUTATED	1	4	3	1	1
CLDN23 WILD-TYPE	12	14	5	13	1

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S57. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CLDN23 MUTATED	4	1	5
CLDN23 WILD-TYPE	17	13	14

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S58. Gene #6: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CLDN23 MUTATED	4	4	2
CLDN23 WILD-TYPE	26	12	6

'TOR3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S59. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TOR3A MUTATED	6	3	1	1
TOR3A WILD-TYPE	15	17	9	8

'TOR3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0136 (Fisher's exact test), Q value = 1

Table S60. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TOR3A MUTATED	0	0	4	6	1
TOR3A WILD-TYPE	13	8	10	7	6

Figure S3. Get High-res Image Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'TOR3A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.138 (Fisher's exact test), Q value = 1

Table S61. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
TOR3A MUTATED	0	1	3	1
TOR3A WILD-TYPE	8	7	3	5

'TOR3A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S62. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TOR3A MUTATED	0	1	2	0	0	1	1	0
TOR3A WILD-TYPE	5	5	3	3	3	0	2	2

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S63. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TOR3A MUTATED	2	1	4	4
TOR3A WILD-TYPE	14	7	10	12

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.005 (Fisher's exact test), Q value = 1

Table S64. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TOR3A MUTATED	0	3	3	5
TOR3A WILD-TYPE	16	13	1	13

Figure S4. Get High-res Image Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S65. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TOR3A MUTATED	5	2	4
TOR3A WILD-TYPE	21	9	14

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S66. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TOR3A MUTATED	2	5	2	2	0
TOR3A WILD-TYPE	11	13	6	12	2

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.912 (Fisher's exact test), Q value = 1

Table S67. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TOR3A MUTATED	5	2	4
TOR3A WILD-TYPE	16	12	15

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S68. Gene #7: 'TOR3A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TOR3A MUTATED	6	4	1
TOR3A WILD-TYPE	24	12	7

'USP42 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S69. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
USP42 MUTATED	5	4	2	4
USP42 WILD-TYPE	16	16	8	5

'USP42 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0469 (Fisher's exact test), Q value = 1

Table S70. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
USP42 MUTATED	2	4	0	3	2
USP42 WILD-TYPE	11	4	14	10	5

Figure S5. Get High-res Image Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'USP42 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S71. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
USP42 MUTATED	2	2	1	2
USP42 WILD-TYPE	6	6	5	4

'USP42 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S72. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
USP42 MUTATED	2	2	0	1	1	1	0	0
USP42 WILD-TYPE	3	4	5	2	2	0	3	2

'USP42 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S73. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
USP42 MUTATED	3	2	3	3
USP42 WILD-TYPE	13	6	11	13

'USP42 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S74. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
USP42 MUTATED	3	4	1	3
USP42 WILD-TYPE	13	12	3	15

'USP42 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S75. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
USP42 MUTATED	6	3	2
USP42 WILD-TYPE	20	8	16

'USP42 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S76. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
USP42 MUTATED	2	3	2	4	0
USP42 WILD-TYPE	11	15	6	10	2

'USP42 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S77. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
USP42 MUTATED	5	2	4
USP42 WILD-TYPE	16	12	15

'USP42 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S78. Gene #8: 'USP42 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
USP42 MUTATED	7	3	1
USP42 WILD-TYPE	23	13	7

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S79. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TP53 MUTATED	5	1	3	3
TP53 WILD-TYPE	16	19	7	6

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S80. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TP53 MUTATED	2	3	3	2	1
TP53 WILD-TYPE	11	5	11	11	6

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.068 (Fisher's exact test), Q value = 1

Table S81. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
TP53 MUTATED	4	3	0	0
TP53 WILD-TYPE	4	5	6	6

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S82. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TP53 MUTATED	3	2	0	1	0	0	1	0
TP53 WILD-TYPE	2	4	5	2	3	1	2	2

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0201 (Fisher's exact test), Q value = 1

Table S83. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TP53 MUTATED	3	2	6	0
TP53 WILD-TYPE	13	6	8	16

Figure S6. Get High-res Image Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S84. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TP53 MUTATED	4	4	1	2
TP53 WILD-TYPE	12	12	3	16

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0158 (Fisher's exact test), Q value = 1

Table S85. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TP53 MUTATED	7	4	0
TP53 WILD-TYPE	19	7	18

Figure S7. Get High-res Image Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S86. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TP53 MUTATED	4	2	2	3	0
TP53 WILD-TYPE	9	16	6	11	2

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00614 (Fisher's exact test), Q value = 1

Table S87. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TP53 MUTATED	8	3	0
TP53 WILD-TYPE	13	11	19

Figure S8. Get High-res Image Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S88. Gene #9: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TP53 MUTATED	9	1	1
TP53 WILD-TYPE	21	15	7

'APOE MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S89. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
APOE MUTATED	3	2	1	1
APOE WILD-TYPE	18	18	9	8

'APOE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S90. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
APOE MUTATED	1	0	3	2	0
APOE WILD-TYPE	12	8	11	11	7

'APOE MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S91. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
APOE MUTATED	1	2	0	0
APOE WILD-TYPE	7	6	6	6

'APOE MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S92. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
APOE MUTATED	0	1	0	0	0	0	1	1
APOE WILD-TYPE	5	5	5	3	3	1	2	1

'APOE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0602 (Fisher's exact test), Q value = 1

Table S93. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
APOE MUTATED	2	0	4	0
APOE WILD-TYPE	14	8	10	16

'APOE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S94. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
APOE MUTATED	1	3	1	1
APOE WILD-TYPE	15	13	3	17

'APOE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.195 (Fisher's exact test), Q value = 1

Table S95. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
APOE MUTATED	2	3	1
APOE WILD-TYPE	24	8	17

'APOE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S96. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
APOE MUTATED	1	3	0	2	0
APOE WILD-TYPE	12	15	8	12	2

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S97. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
APOE MUTATED	2	3	1
APOE WILD-TYPE	19	11	18

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S98. Gene #10: 'APOE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
APOE MUTATED	3	2	1
APOE WILD-TYPE	27	14	7

'ZAR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S99. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZAR1 MUTATED	4	3	1	3
ZAR1 WILD-TYPE	17	17	9	6

'ZAR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S100. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZAR1 MUTATED	3	1	1	2	2
ZAR1 WILD-TYPE	10	7	13	11	5

'ZAR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S101. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
ZAR1 MUTATED	0	2	0	2
ZAR1 WILD-TYPE	8	6	6	4

'ZAR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S102. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZAR1 MUTATED	0	2	1	0	1	0	0	0
ZAR1 WILD-TYPE	5	4	4	3	2	1	3	2

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S103. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZAR1 MUTATED	3	0	2	4
ZAR1 WILD-TYPE	13	8	12	12

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S104. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZAR1 MUTATED	3	2	0	4
ZAR1 WILD-TYPE	13	14	4	14

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.716 (Fisher's exact test), Q value = 1

Table S105. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZAR1 MUTATED	4	1	4
ZAR1 WILD-TYPE	22	10	14

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.972 (Fisher's exact test), Q value = 1

Table S106. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZAR1 MUTATED	2	4	1	2	0
ZAR1 WILD-TYPE	11	14	7	12	2

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S107. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZAR1 MUTATED	4	2	3
ZAR1 WILD-TYPE	17	12	16

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S108. Gene #11: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZAR1 MUTATED	4	4	1
ZAR1 WILD-TYPE	26	12	7

'ASPDH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.301 (Fisher's exact test), Q value = 1

Table S109. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ASPDH MUTATED	3	2	3	0
ASPDH WILD-TYPE	18	18	7	9

'ASPDH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S110. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ASPDH MUTATED	3	1	3	1	0
ASPDH WILD-TYPE	10	7	11	12	7

'ASPDH MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.717 (Fisher's exact test), Q value = 1

Table S111. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
ASPDH MUTATED	2	2	0	1
ASPDH WILD-TYPE	6	6	6	5

'ASPDH MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S112. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ASPDH MUTATED	0	3	0	1	0	0	1	0
ASPDH WILD-TYPE	5	3	5	2	3	1	2	2

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0236 (Fisher's exact test), Q value = 1

Table S113. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ASPDH MUTATED	3	0	5	0
ASPDH WILD-TYPE	13	8	9	16

Figure S9. Get High-res Image Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S114. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ASPDH MUTATED	3	4	0	1
ASPDH WILD-TYPE	13	12	4	17

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S115. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ASPDH MUTATED	5	2	1
ASPDH WILD-TYPE	21	9	17

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.031 (Fisher's exact test), Q value = 1

Table S116. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ASPDH MUTATED	4	0	0	4	0
ASPDH WILD-TYPE	9	18	8	10	2

Figure S10. Get High-res Image Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S117. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ASPDH MUTATED	3	4	1
ASPDH WILD-TYPE	18	10	18

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.081 (Fisher's exact test), Q value = 1

Table S118. Gene #12: 'ASPDH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ASPDH MUTATED	7	0	1
ASPDH WILD-TYPE	23	16	7

'KCNK17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S119. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KCNK17 MUTATED	3	1	2	3
KCNK17 WILD-TYPE	18	19	8	6

'KCNK17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0391 (Fisher's exact test), Q value = 1

Table S120. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KCNK17 MUTATED	0	2	5	1	0
KCNK17 WILD-TYPE	13	6	9	12	7

Figure S11. Get High-res Image Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'KCNK17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S121. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
KCNK17 MUTATED	1	4	0	1
KCNK17 WILD-TYPE	7	4	6	5

'KCNK17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S122. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KCNK17 MUTATED	1	3	0	0	1	0	0	1
KCNK17 WILD-TYPE	4	3	5	3	2	1	3	1

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 1

Table S123. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KCNK17 MUTATED	1	1	5	1
KCNK17 WILD-TYPE	15	7	9	15

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00942 (Fisher's exact test), Q value = 1

Table S124. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KCNK17 MUTATED	0	6	1	1
KCNK17 WILD-TYPE	16	10	3	17

Figure S12. Get High-res Image Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S125. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KCNK17 MUTATED	4	2	2
KCNK17 WILD-TYPE	22	9	16

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S126. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KCNK17 MUTATED	3	1	2	2	0
KCNK17 WILD-TYPE	10	17	6	12	2

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.717 (Fisher's exact test), Q value = 1

Table S127. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KCNK17 MUTATED	4	1	3
KCNK17 WILD-TYPE	17	13	16

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S128. Gene #13: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KCNK17 MUTATED	5	1	2
KCNK17 WILD-TYPE	25	15	6

'LZTR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0517 (Fisher's exact test), Q value = 1

Table S129. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
LZTR1 MUTATED	5	0	1	0
LZTR1 WILD-TYPE	16	20	9	9

'LZTR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S130. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
LZTR1 MUTATED	2	0	1	1	0
LZTR1 WILD-TYPE	11	8	13	12	7

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0896 (Fisher's exact test), Q value = 1

Table S131. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
LZTR1 MUTATED	3	1	0	0
LZTR1 WILD-TYPE	13	7	14	16

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S132. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LZTR1 MUTATED	2	1	1	0
LZTR1 WILD-TYPE	14	15	3	18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S133. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
LZTR1 MUTATED	3	1	0
LZTR1 WILD-TYPE	23	10	18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0143 (Fisher's exact test), Q value = 1

Table S134. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LZTR1 MUTATED	0	0	0	3	1
LZTR1 WILD-TYPE	13	18	8	11	1

Figure S13. Get High-res Image Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S135. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
LZTR1 MUTATED	2	1	1
LZTR1 WILD-TYPE	19	13	18

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S136. Gene #14: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
LZTR1 MUTATED	3	0	1
LZTR1 WILD-TYPE	27	16	7

'ERCC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S137. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ERCC2 MUTATED	4	3	2	1
ERCC2 WILD-TYPE	17	17	8	8

'ERCC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S138. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ERCC2 MUTATED	4	3	2	1	0
ERCC2 WILD-TYPE	9	5	12	12	7

'ERCC2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 1

Table S139. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
ERCC2 MUTATED	3	4	1	0
ERCC2 WILD-TYPE	5	4	5	6

'ERCC2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S140. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ERCC2 MUTATED	2	3	0	1	0	1	0	1
ERCC2 WILD-TYPE	3	3	5	2	3	0	3	1

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.482 (Fisher's exact test), Q value = 1

Table S141. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ERCC2 MUTATED	4	2	3	1
ERCC2 WILD-TYPE	12	6	11	15

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S142. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ERCC2 MUTATED	5	4	0	1
ERCC2 WILD-TYPE	11	12	4	17

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S143. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ERCC2 MUTATED	6	2	2
ERCC2 WILD-TYPE	20	9	16

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S144. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ERCC2 MUTATED	3	2	0	5	0
ERCC2 WILD-TYPE	10	16	8	9	2

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S145. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ERCC2 MUTATED	6	2	2
ERCC2 WILD-TYPE	15	12	17

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.207 (Fisher's exact test), Q value = 1

Table S146. Gene #15: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ERCC2 MUTATED	8	2	0
ERCC2 WILD-TYPE	22	14	8

'RINL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S147. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RINL MUTATED	5	2	0	1
RINL WILD-TYPE	16	18	10	8

'RINL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.678 (Fisher's exact test), Q value = 1

Table S148. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RINL MUTATED	3	1	1	2	0
RINL WILD-TYPE	10	7	13	11	7

'RINL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S149. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
RINL MUTATED	1	1	0	2
RINL WILD-TYPE	7	7	6	4

'RINL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S150. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RINL MUTATED	1	0	1	0	1	0	0	1
RINL WILD-TYPE	4	6	4	3	2	1	3	1

'RINL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S151. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RINL MUTATED	4	1	1	1
RINL WILD-TYPE	12	7	13	15

'RINL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.273 (Fisher's exact test), Q value = 1

Table S152. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RINL MUTATED	4	1	1	1
RINL WILD-TYPE	12	15	3	17

'RINL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S153. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RINL MUTATED	3	2	2
RINL WILD-TYPE	23	9	16

'RINL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S154. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RINL MUTATED	0	3	0	4	0
RINL WILD-TYPE	13	15	8	10	2

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S155. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RINL MUTATED	1	3	3
RINL WILD-TYPE	20	11	16

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S156. Gene #16: 'RINL MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RINL MUTATED	3	3	1
RINL WILD-TYPE	27	13	7

'SYT8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S157. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SYT8 MUTATED	1	4	2	1
SYT8 WILD-TYPE	20	16	8	8

'SYT8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S158. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SYT8 MUTATED	0	2	2	1	1
SYT8 WILD-TYPE	13	6	12	12	6

'SYT8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S159. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
SYT8 MUTATED	1	1	1	0
SYT8 WILD-TYPE	7	7	5	6

'SYT8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S160. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SYT8 MUTATED	1	1	1	0	0	0	0	0
SYT8 WILD-TYPE	4	5	4	3	3	1	3	2

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0415 (Fisher's exact test), Q value = 1

Table S161. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SYT8 MUTATED	0	3	1	2
SYT8 WILD-TYPE	16	5	13	14

Figure S14. Get High-res Image Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.177 (Fisher's exact test), Q value = 1

Table S162. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SYT8 MUTATED	0	4	0	2
SYT8 WILD-TYPE	16	12	4	16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S163. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SYT8 MUTATED	3	1	2
SYT8 WILD-TYPE	23	10	16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S164. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SYT8 MUTATED	1	3	1	0	1
SYT8 WILD-TYPE	12	15	7	14	1

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.751 (Fisher's exact test), Q value = 1

Table S165. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SYT8 MUTATED	2	1	3
SYT8 WILD-TYPE	19	13	16

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.496 (Fisher's exact test), Q value = 1

Table S166. Gene #17: 'SYT8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SYT8 MUTATED	3	3	0
SYT8 WILD-TYPE	27	13	8

'LRIG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S167. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
LRIG1 MUTATED	5	4	3	4
LRIG1 WILD-TYPE	16	16	7	5

'LRIG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S168. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
LRIG1 MUTATED	3	2	2	3	1
LRIG1 WILD-TYPE	10	6	12	10	6

'LRIG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S169. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
LRIG1 MUTATED	2	0	0	2
LRIG1 WILD-TYPE	6	8	6	4

'LRIG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S170. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
LRIG1 MUTATED	1	1	1	1	0	0	0	0
LRIG1 WILD-TYPE	4	5	4	2	3	1	3	2

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S171. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
LRIG1 MUTATED	2	2	3	3
LRIG1 WILD-TYPE	14	6	11	13

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S172. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LRIG1 MUTATED	3	2	0	5
LRIG1 WILD-TYPE	13	14	4	13

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S173. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
LRIG1 MUTATED	4	4	3
LRIG1 WILD-TYPE	22	7	15

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S174. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LRIG1 MUTATED	1	3	3	4	0
LRIG1 WILD-TYPE	12	15	5	10	2

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.577 (Fisher's exact test), Q value = 1

Table S175. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
LRIG1 MUTATED	3	4	4
LRIG1 WILD-TYPE	18	10	15

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S176. Gene #18: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
LRIG1 MUTATED	7	3	1
LRIG1 WILD-TYPE	23	13	7

'C1ORF106 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S177. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C1ORF106 MUTATED	4	2	2	1
C1ORF106 WILD-TYPE	17	18	8	8

'C1ORF106 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S178. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C1ORF106 MUTATED	3	0	2	1	2
C1ORF106 WILD-TYPE	10	8	12	12	5

'C1ORF106 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 1

Table S179. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
C1ORF106 MUTATED	1	1	0	3
C1ORF106 WILD-TYPE	7	7	6	3

'C1ORF106 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0475 (Fisher's exact test), Q value = 1

Table S180. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
C1ORF106 MUTATED	1	0	0	2	2	0	0	0
C1ORF106 WILD-TYPE	4	6	5	1	1	1	3	2

Figure S15. Get High-res Image Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S181. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C1ORF106 MUTATED	4	2	1	1
C1ORF106 WILD-TYPE	12	6	13	15

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S182. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C1ORF106 MUTATED	3	2	1	2
C1ORF106 WILD-TYPE	13	14	3	16

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S183. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C1ORF106 MUTATED	5	2	1
C1ORF106 WILD-TYPE	21	9	17

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S184. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C1ORF106 MUTATED	1	2	2	3	0
C1ORF106 WILD-TYPE	12	16	6	11	2

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.053 (Fisher's exact test), Q value = 1

Table S185. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C1ORF106 MUTATED	5	3	0
C1ORF106 WILD-TYPE	16	11	19

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S186. Gene #19: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C1ORF106 MUTATED	5	2	1
C1ORF106 WILD-TYPE	25	14	7

'GPRIN2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.867 (Fisher's exact test), Q value = 1

Table S187. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
GPRIN2 MUTATED	2	3	2	1
GPRIN2 WILD-TYPE	19	17	8	8

'GPRIN2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S188. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
GPRIN2 MUTATED	1	0	4	1	1
GPRIN2 WILD-TYPE	12	8	10	12	6

'GPRIN2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S189. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
GPRIN2 MUTATED	0	2	0	2
GPRIN2 WILD-TYPE	8	6	6	4

'GPRIN2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S190. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
GPRIN2 MUTATED	0	1	1	0	1	0	0	1
GPRIN2 WILD-TYPE	5	5	4	3	2	1	3	1

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S191. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
GPRIN2 MUTATED	1	1	3	2
GPRIN2 WILD-TYPE	15	7	11	14

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S192. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GPRIN2 MUTATED	1	4	0	2
GPRIN2 WILD-TYPE	15	12	4	16

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S193. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
GPRIN2 MUTATED	2	2	3
GPRIN2 WILD-TYPE	24	9	15

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S194. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GPRIN2 MUTATED	1	4	1	1	0
GPRIN2 WILD-TYPE	12	14	7	13	2

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S195. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
GPRIN2 MUTATED	2	3	2
GPRIN2 WILD-TYPE	19	11	17

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.183 (Fisher's exact test), Q value = 1

Table S196. Gene #20: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
GPRIN2 MUTATED	2	4	1
GPRIN2 WILD-TYPE	28	12	7

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S197. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CTNNB1 MUTATED	4	2	1	0
CTNNB1 WILD-TYPE	17	18	9	9

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S198. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CTNNB1 MUTATED	3	2	1	0	0
CTNNB1 WILD-TYPE	10	6	13	13	7

'CTNNB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S199. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
CTNNB1 MUTATED	2	0	0	2
CTNNB1 WILD-TYPE	6	8	6	4

'CTNNB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.395 (Fisher's exact test), Q value = 1

Table S200. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CTNNB1 MUTATED	1	1	0	0	2	0	0	0
CTNNB1 WILD-TYPE	4	5	5	3	1	1	3	2

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0176 (Fisher's exact test), Q value = 1

Table S201. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CTNNB1 MUTATED	4	2	0	0
CTNNB1 WILD-TYPE	12	6	14	16

Figure S16. Get High-res Image Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0235 (Fisher's exact test), Q value = 1

Table S202. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CTNNB1 MUTATED	5	1	0	0
CTNNB1 WILD-TYPE	11	15	4	18

Figure S17. Get High-res Image Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00079 (Fisher's exact test), Q value = 0.77

Table S203. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CTNNB1 MUTATED	1	5	0
CTNNB1 WILD-TYPE	25	6	18

Figure S18. Get High-res Image Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S204. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CTNNB1 MUTATED	0	2	0	4	0
CTNNB1 WILD-TYPE	13	16	8	10	2

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S205. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CTNNB1 MUTATED	3	3	0
CTNNB1 WILD-TYPE	18	11	19

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S206. Gene #21: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CTNNB1 MUTATED	4	2	0
CTNNB1 WILD-TYPE	26	14	8

'C16ORF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S207. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C16ORF3 MUTATED	2	2	0	1
C16ORF3 WILD-TYPE	19	18	10	8

'C16ORF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00076 (Fisher's exact test), Q value = 0.74

Table S208. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C16ORF3 MUTATED	0	4	0	0	1
C16ORF3 WILD-TYPE	13	4	14	13	6

Figure S19. Get High-res Image Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'C16ORF3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.59 (Fisher's exact test), Q value = 1

Table S209. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
C16ORF3 MUTATED	1	2	0	0
C16ORF3 WILD-TYPE	7	6	6	6

'C16ORF3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S210. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
C16ORF3 MUTATED	1	2	0	0	0	0	0	0
C16ORF3 WILD-TYPE	4	4	5	3	3	1	3	2

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S211. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C16ORF3 MUTATED	1	1	2	1
C16ORF3 WILD-TYPE	15	7	12	15

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S212. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C16ORF3 MUTATED	2	2	0	1
C16ORF3 WILD-TYPE	14	14	4	17

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S213. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C16ORF3 MUTATED	2	2	1
C16ORF3 WILD-TYPE	24	9	17

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S214. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C16ORF3 MUTATED	1	2	1	1	0
C16ORF3 WILD-TYPE	12	16	7	13	2

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S215. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C16ORF3 MUTATED	3	1	1
C16ORF3 WILD-TYPE	18	13	18

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.835 (Fisher's exact test), Q value = 1

Table S216. Gene #22: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C16ORF3 MUTATED	3	2	0
C16ORF3 WILD-TYPE	27	14	8

'CCDC105 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S217. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CCDC105 MUTATED	2	2	1	1
CCDC105 WILD-TYPE	19	18	9	8

'CCDC105 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0109 (Fisher's exact test), Q value = 1

Table S218. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CCDC105 MUTATED	1	3	0	0	2
CCDC105 WILD-TYPE	12	5	14	13	5

Figure S20. Get High-res Image Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CCDC105 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S219. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
CCDC105 MUTATED	1	2	0	0
CCDC105 WILD-TYPE	7	6	6	6

'CCDC105 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S220. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CCDC105 MUTATED	1	1	0	0	0	0	0	1
CCDC105 WILD-TYPE	4	5	5	3	3	1	3	1

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S221. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CCDC105 MUTATED	1	1	2	2
CCDC105 WILD-TYPE	15	7	12	14

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S222. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CCDC105 MUTATED	3	1	0	2
CCDC105 WILD-TYPE	13	15	4	16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S223. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CCDC105 MUTATED	3	1	2
CCDC105 WILD-TYPE	23	10	16

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0535 (Fisher's exact test), Q value = 1

Table S224. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CCDC105 MUTATED	1	0	2	2	1
CCDC105 WILD-TYPE	12	18	6	12	1

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S225. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CCDC105 MUTATED	4	0	2
CCDC105 WILD-TYPE	17	14	17

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.208 (Fisher's exact test), Q value = 1

Table S226. Gene #23: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CCDC105 MUTATED	5	0	1
CCDC105 WILD-TYPE	25	16	7

'RGS9BP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S227. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RGS9BP MUTATED	3	3	2	0
RGS9BP WILD-TYPE	18	17	8	9

'RGS9BP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S228. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RGS9BP MUTATED	3	0	3	1	1
RGS9BP WILD-TYPE	10	8	11	12	6

'RGS9BP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S229. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
RGS9BP MUTATED	1	1	1	0
RGS9BP WILD-TYPE	7	7	5	6

'RGS9BP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S230. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RGS9BP MUTATED	0	2	0	0	0	1	0	0
RGS9BP WILD-TYPE	5	4	5	3	3	0	3	2

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S231. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RGS9BP MUTATED	2	1	2	2
RGS9BP WILD-TYPE	14	7	12	14

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S232. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RGS9BP MUTATED	2	3	0	2
RGS9BP WILD-TYPE	14	13	4	16

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 1

Table S233. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RGS9BP MUTATED	2	3	3
RGS9BP WILD-TYPE	24	8	15

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S234. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RGS9BP MUTATED	2	2	1	3	0
RGS9BP WILD-TYPE	11	16	7	11	2

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S235. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RGS9BP MUTATED	2	4	2
RGS9BP WILD-TYPE	19	10	17

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S236. Gene #24: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RGS9BP MUTATED	4	2	2
RGS9BP WILD-TYPE	26	14	6

'HHIPL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.276 (Fisher's exact test), Q value = 1

Table S237. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
HHIPL1 MUTATED	3	1	0	2
HHIPL1 WILD-TYPE	18	19	10	7

'HHIPL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S238. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
HHIPL1 MUTATED	2	0	0	2	1
HHIPL1 WILD-TYPE	11	8	14	11	6

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S239. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
HHIPL1 MUTATED	3	0	1	1
HHIPL1 WILD-TYPE	13	8	13	15

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.513 (Fisher's exact test), Q value = 1

Table S240. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
HHIPL1 MUTATED	2	1	1	1
HHIPL1 WILD-TYPE	14	15	3	17

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 1

Table S241. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
HHIPL1 MUTATED	4	1	0
HHIPL1 WILD-TYPE	22	10	18

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S242. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
HHIPL1 MUTATED	2	0	1	2	0
HHIPL1 WILD-TYPE	11	18	7	12	2

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S243. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
HHIPL1 MUTATED	4	0	1
HHIPL1 WILD-TYPE	17	14	18

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S244. Gene #25: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
HHIPL1 MUTATED	4	0	1
HHIPL1 WILD-TYPE	26	16	7

'C10ORF95 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S245. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C10ORF95 MUTATED	2	0	2	1
C10ORF95 WILD-TYPE	19	20	8	8

'C10ORF95 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.378 (Fisher's exact test), Q value = 1

Table S246. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C10ORF95 MUTATED	1	0	3	0	1
C10ORF95 WILD-TYPE	12	8	11	13	6

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.513 (Fisher's exact test), Q value = 1

Table S247. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C10ORF95 MUTATED	1	2	1	1
C10ORF95 WILD-TYPE	15	6	13	15

'C10ORF95 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S248. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C10ORF95 MUTATED	1	2	0	2
C10ORF95 WILD-TYPE	15	14	4	16

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S249. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C10ORF95 MUTATED	4	0	1
C10ORF95 WILD-TYPE	22	11	17

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 1

Table S250. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C10ORF95 MUTATED	1	1	1	1	1
C10ORF95 WILD-TYPE	12	17	7	13	1

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S251. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C10ORF95 MUTATED	2	1	1
C10ORF95 WILD-TYPE	19	13	18

'C10ORF95 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S252. Gene #26: 'C10ORF95 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C10ORF95 MUTATED	3	1	0
C10ORF95 WILD-TYPE	27	15	8

'TSC22D2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.947 (Fisher's exact test), Q value = 1

Table S253. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TSC22D2 MUTATED	4	2	1	1
TSC22D2 WILD-TYPE	17	18	9	8

'TSC22D2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S254. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TSC22D2 MUTATED	2	0	2	1	2
TSC22D2 WILD-TYPE	11	8	12	12	5

'TSC22D2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S255. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
TSC22D2 MUTATED	0	1	1	1
TSC22D2 WILD-TYPE	8	7	5	5

'TSC22D2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S256. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TSC22D2 MUTATED	0	1	1	0	1	0	0	0
TSC22D2 WILD-TYPE	5	5	4	3	2	1	3	2

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S257. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TSC22D2 MUTATED	3	0	2	2
TSC22D2 WILD-TYPE	13	8	12	14

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S258. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TSC22D2 MUTATED	2	2	1	2
TSC22D2 WILD-TYPE	14	14	3	16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S259. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TSC22D2 MUTATED	3	2	2
TSC22D2 WILD-TYPE	23	9	16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S260. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TSC22D2 MUTATED	1	2	0	4	0
TSC22D2 WILD-TYPE	12	16	8	10	2

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S261. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TSC22D2 MUTATED	1	3	3
TSC22D2 WILD-TYPE	20	11	16

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S262. Gene #27: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TSC22D2 MUTATED	4	2	1
TSC22D2 WILD-TYPE	26	14	7

'NOXA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.145 (Fisher's exact test), Q value = 1

Table S263. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NOXA1 MUTATED	3	0	2	0
NOXA1 WILD-TYPE	18	20	8	9

'NOXA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S264. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NOXA1 MUTATED	2	0	1	0	0
NOXA1 WILD-TYPE	11	8	13	13	7

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 1

Table S265. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	14	7	14	16

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S266. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	14	15	4	18

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 1

Table S267. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	23	11	18

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S268. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NOXA1 MUTATED	1	0	0	2	0
NOXA1 WILD-TYPE	12	18	8	12	2

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 1

Table S269. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NOXA1 MUTATED	1	2	0
NOXA1 WILD-TYPE	20	12	19

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.722 (Fisher's exact test), Q value = 1

Table S270. Gene #28: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	27	16	8

'THEM4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.281 (Fisher's exact test), Q value = 1

Table S271. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
THEM4 MUTATED	3	0	1	1
THEM4 WILD-TYPE	18	20	9	8

'THEM4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S272. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
THEM4 MUTATED	1	1	1	0	1
THEM4 WILD-TYPE	12	7	13	13	6

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S273. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
THEM4 MUTATED	1	1	2	0
THEM4 WILD-TYPE	15	7	12	16

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S274. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
THEM4 MUTATED	2	1	0	1
THEM4 WILD-TYPE	14	15	4	17

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S275. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
THEM4 MUTATED	2	2	0
THEM4 WILD-TYPE	24	9	18

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S276. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
THEM4 MUTATED	0	0	1	3	0
THEM4 WILD-TYPE	13	18	7	11	2

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S277. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
THEM4 MUTATED	3	1	0
THEM4 WILD-TYPE	18	13	19

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S278. Gene #29: 'THEM4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
THEM4 MUTATED	4	0	0
THEM4 WILD-TYPE	26	16	8

'ATXN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 1

Table S279. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ATXN1 MUTATED	2	4	3	1
ATXN1 WILD-TYPE	19	16	7	8

'ATXN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 1

Table S280. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ATXN1 MUTATED	1	4	2	1	1
ATXN1 WILD-TYPE	12	4	12	12	6

'ATXN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S281. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
ATXN1 MUTATED	2	1	1	0
ATXN1 WILD-TYPE	6	7	5	6

'ATXN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S282. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ATXN1 MUTATED	2	1	1	0	0	0	0	0
ATXN1 WILD-TYPE	3	5	4	3	3	1	3	2

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S283. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ATXN1 MUTATED	2	3	3	1
ATXN1 WILD-TYPE	14	5	11	15

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S284. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ATXN1 MUTATED	3	4	0	2
ATXN1 WILD-TYPE	13	12	4	16

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S285. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ATXN1 MUTATED	5	3	1
ATXN1 WILD-TYPE	21	8	17

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S286. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ATXN1 MUTATED	2	2	2	3	0
ATXN1 WILD-TYPE	11	16	6	11	2

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S287. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ATXN1 MUTATED	6	1	2
ATXN1 WILD-TYPE	15	13	17

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S288. Gene #30: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ATXN1 MUTATED	7	2	0
ATXN1 WILD-TYPE	23	14	8

'PLIN5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S289. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PLIN5 MUTATED	1	3	0	1
PLIN5 WILD-TYPE	20	17	10	8

'PLIN5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S290. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PLIN5 MUTATED	1	2	1	1	0
PLIN5 WILD-TYPE	12	6	13	12	7

'PLIN5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S291. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
PLIN5 MUTATED	0	2	0	1
PLIN5 WILD-TYPE	8	6	6	5

'PLIN5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.385 (Fisher's exact test), Q value = 1

Table S292. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PLIN5 MUTATED	0	1	0	0	1	0	0	1
PLIN5 WILD-TYPE	5	5	5	3	2	1	3	1

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S293. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PLIN5 MUTATED	1	1	2	1
PLIN5 WILD-TYPE	15	7	12	15

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S294. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PLIN5 MUTATED	1	3	0	1
PLIN5 WILD-TYPE	15	13	4	17

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S295. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PLIN5 MUTATED	1	2	2
PLIN5 WILD-TYPE	25	9	16

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S296. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PLIN5 MUTATED	1	4	0	0	0
PLIN5 WILD-TYPE	12	14	8	14	2

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S297. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PLIN5 MUTATED	1	1	3
PLIN5 WILD-TYPE	20	13	16

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0465 (Fisher's exact test), Q value = 1

Table S298. Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PLIN5 MUTATED	1	4	0
PLIN5 WILD-TYPE	29	12	8

Figure S21. Get High-res Image Gene #31: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'OPRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.968 (Fisher's exact test), Q value = 1

Table S299. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
OPRD1 MUTATED	5	4	2	1
OPRD1 WILD-TYPE	16	16	8	8

'OPRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S300. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
OPRD1 MUTATED	3	1	3	1	3
OPRD1 WILD-TYPE	10	7	11	12	4

'OPRD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 1

Table S301. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
OPRD1 MUTATED	0	3	1	2
OPRD1 WILD-TYPE	8	5	5	4

'OPRD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.478 (Fisher's exact test), Q value = 1

Table S302. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
OPRD1 MUTATED	0	2	1	1	2	0	0	0
OPRD1 WILD-TYPE	5	4	4	2	1	1	3	2

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S303. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
OPRD1 MUTATED	4	2	3	2
OPRD1 WILD-TYPE	12	6	11	14

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S304. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
OPRD1 MUTATED	3	4	1	3
OPRD1 WILD-TYPE	13	12	3	15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S305. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
OPRD1 MUTATED	5	4	2
OPRD1 WILD-TYPE	21	7	16

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S306. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
OPRD1 MUTATED	1	5	1	4	0
OPRD1 WILD-TYPE	12	13	7	10	2

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S307. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
OPRD1 MUTATED	4	3	4
OPRD1 WILD-TYPE	17	11	15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S308. Gene #32: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
OPRD1 MUTATED	5	5	1
OPRD1 WILD-TYPE	25	11	7

'KRTAP4-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S309. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KRTAP4-5 MUTATED	2	3	0	0
KRTAP4-5 WILD-TYPE	19	17	10	9

'KRTAP4-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 1

Table S310. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KRTAP4-5 MUTATED	1	2	0	1	0
KRTAP4-5 WILD-TYPE	12	6	14	12	7

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.909 (Fisher's exact test), Q value = 1

Table S311. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KRTAP4-5 MUTATED	2	0	1	1
KRTAP4-5 WILD-TYPE	14	8	13	15

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S312. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KRTAP4-5 MUTATED	2	1	0	1
KRTAP4-5 WILD-TYPE	14	15	4	17

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S313. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KRTAP4-5 MUTATED	2	1	1
KRTAP4-5 WILD-TYPE	24	10	17

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S314. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KRTAP4-5 MUTATED	1	1	0	2	0
KRTAP4-5 WILD-TYPE	12	17	8	12	2

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S315. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KRTAP4-5 MUTATED	3	0	1
KRTAP4-5 WILD-TYPE	18	14	18

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S316. Gene #33: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KRTAP4-5 MUTATED	3	1	0
KRTAP4-5 WILD-TYPE	27	15	8

'C19ORF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S317. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C19ORF10 MUTATED	3	2	0	1
C19ORF10 WILD-TYPE	18	18	10	8

'C19ORF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S318. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C19ORF10 MUTATED	2	1	3	0	0
C19ORF10 WILD-TYPE	11	7	11	13	7

'C19ORF10 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S319. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
C19ORF10 MUTATED	1	2	0	1
C19ORF10 WILD-TYPE	7	6	6	5

'C19ORF10 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S320. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
C19ORF10 MUTATED	0	2	0	0	1	0	0	1
C19ORF10 WILD-TYPE	5	4	5	3	2	1	3	1

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.241 (Fisher's exact test), Q value = 1

Table S321. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C19ORF10 MUTATED	2	2	2	0
C19ORF10 WILD-TYPE	14	6	12	16

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S322. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C19ORF10 MUTATED	2	4	0	0
C19ORF10 WILD-TYPE	14	12	4	18

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S323. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C19ORF10 MUTATED	3	2	1
C19ORF10 WILD-TYPE	23	9	17

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S324. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C19ORF10 MUTATED	2	2	0	2	0
C19ORF10 WILD-TYPE	11	16	8	12	2

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S325. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C19ORF10 MUTATED	3	2	1
C19ORF10 WILD-TYPE	18	12	18

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S326. Gene #34: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C19ORF10 MUTATED	4	2	0
C19ORF10 WILD-TYPE	26	14	8

'AATK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 1

Table S327. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AATK MUTATED	0	4	1	1
AATK WILD-TYPE	21	16	9	8

'AATK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S328. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
AATK MUTATED	0	1	2	0	1
AATK WILD-TYPE	13	7	12	13	6

'AATK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S329. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
AATK MUTATED	0	1	2	1
AATK WILD-TYPE	16	7	12	15

'AATK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 1

Table S330. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AATK MUTATED	0	3	0	1
AATK WILD-TYPE	16	13	4	17

'AATK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S331. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
AATK MUTATED	2	1	1
AATK WILD-TYPE	24	10	17

'AATK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S332. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AATK MUTATED	2	2	0	0	0
AATK WILD-TYPE	11	16	8	14	2

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S333. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
AATK MUTATED	2	1	1
AATK WILD-TYPE	19	13	18

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S334. Gene #35: 'AATK MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
AATK MUTATED	2	2	0
AATK WILD-TYPE	28	14	8

'SARM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 1

Table S335. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SARM1 MUTATED	3	0	2	1
SARM1 WILD-TYPE	18	20	8	8

'SARM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S336. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SARM1 MUTATED	0	1	3	1	0
SARM1 WILD-TYPE	13	7	11	12	7

'SARM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S337. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
SARM1 MUTATED	1	2	0	1
SARM1 WILD-TYPE	7	6	6	5

'SARM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S338. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SARM1 MUTATED	1	1	0	0	1	0	0	1
SARM1 WILD-TYPE	4	5	5	3	2	1	3	1

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S339. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SARM1 MUTATED	1	1	3	0
SARM1 WILD-TYPE	15	7	11	16

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S340. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SARM1 MUTATED	1	3	1	0
SARM1 WILD-TYPE	15	13	3	18

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.266 (Fisher's exact test), Q value = 1

Table S341. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SARM1 MUTATED	1	2	2
SARM1 WILD-TYPE	25	9	16

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S342. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SARM1 MUTATED	2	2	0	1	0
SARM1 WILD-TYPE	11	16	8	13	2

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S343. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SARM1 MUTATED	1	1	3
SARM1 WILD-TYPE	20	13	16

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0793 (Fisher's exact test), Q value = 1

Table S344. Gene #36: 'SARM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SARM1 MUTATED	1	2	2
SARM1 WILD-TYPE	29	14	6

'TRIOBP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S345. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TRIOBP MUTATED	4	4	2	0
TRIOBP WILD-TYPE	17	16	8	9

'TRIOBP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S346. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TRIOBP MUTATED	3	1	0	3	2
TRIOBP WILD-TYPE	10	7	14	10	5

'TRIOBP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S347. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
TRIOBP MUTATED	2	0	1	0
TRIOBP WILD-TYPE	6	8	5	6

'TRIOBP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S348. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TRIOBP MUTATED	1	0	0	0	0	0	2	0
TRIOBP WILD-TYPE	4	6	5	3	3	1	1	2

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S349. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TRIOBP MUTATED	2	1	2	3
TRIOBP WILD-TYPE	14	7	12	13

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 1

Table S350. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TRIOBP MUTATED	3	0	0	5
TRIOBP WILD-TYPE	13	16	4	13

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S351. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TRIOBP MUTATED	4	1	4
TRIOBP WILD-TYPE	22	10	14

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S352. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TRIOBP MUTATED	2	2	2	3	0
TRIOBP WILD-TYPE	11	16	6	11	2

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S353. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TRIOBP MUTATED	4	2	3
TRIOBP WILD-TYPE	17	12	16

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S354. Gene #37: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TRIOBP MUTATED	5	2	2
TRIOBP WILD-TYPE	25	14	6

'ZNF598 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S355. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZNF598 MUTATED	8	2	1	1
ZNF598 WILD-TYPE	13	18	9	8

'ZNF598 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S356. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZNF598 MUTATED	3	0	2	4	0
ZNF598 WILD-TYPE	10	8	12	9	7

'ZNF598 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S357. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
ZNF598 MUTATED	1	1	1	3
ZNF598 WILD-TYPE	7	7	5	3

'ZNF598 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S358. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZNF598 MUTATED	1	0	2	1	1	0	1	0
ZNF598 WILD-TYPE	4	6	3	2	2	1	2	2

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S359. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZNF598 MUTATED	4	0	3	2
ZNF598 WILD-TYPE	12	8	11	14

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.953 (Fisher's exact test), Q value = 1

Table S360. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZNF598 MUTATED	3	2	1	3
ZNF598 WILD-TYPE	13	14	3	15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S361. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZNF598 MUTATED	4	2	3
ZNF598 WILD-TYPE	22	9	15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S362. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZNF598 MUTATED	1	3	0	5	0
ZNF598 WILD-TYPE	12	15	8	9	2

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.901 (Fisher's exact test), Q value = 1

Table S363. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZNF598 MUTATED	3	2	4
ZNF598 WILD-TYPE	18	12	15

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S364. Gene #38: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZNF598 MUTATED	5	3	1
ZNF598 WILD-TYPE	25	13	7

'WDR34 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S365. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
WDR34 MUTATED	3	1	0	1
WDR34 WILD-TYPE	18	19	10	8

'WDR34 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S366. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
WDR34 MUTATED	2	0	1	1	1
WDR34 WILD-TYPE	11	8	13	12	6

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S367. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
WDR34 MUTATED	2	0	1	2
WDR34 WILD-TYPE	14	8	13	14

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S368. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
WDR34 MUTATED	2	2	0	1
WDR34 WILD-TYPE	14	14	4	17

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S369. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
WDR34 MUTATED	3	1	1
WDR34 WILD-TYPE	23	10	17

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S370. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
WDR34 MUTATED	1	1	0	3	0
WDR34 WILD-TYPE	12	17	8	11	2

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S371. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
WDR34 MUTATED	2	2	1
WDR34 WILD-TYPE	19	12	18

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S372. Gene #39: 'WDR34 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
WDR34 MUTATED	4	0	1
WDR34 WILD-TYPE	26	16	7

'ZNF628 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S373. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZNF628 MUTATED	5	1	0	1
ZNF628 WILD-TYPE	16	19	10	8

'ZNF628 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S374. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ZNF628 MUTATED	2	1	1	1	0
ZNF628 WILD-TYPE	11	7	13	12	7

'ZNF628 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S375. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
ZNF628 MUTATED	2	1	0	0
ZNF628 WILD-TYPE	6	7	6	6

'ZNF628 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S376. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ZNF628 MUTATED	1	1	0	0	0	0	0	1
ZNF628 WILD-TYPE	4	5	5	3	3	1	3	1

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S377. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ZNF628 MUTATED	3	1	1	0
ZNF628 WILD-TYPE	13	7	13	16

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S378. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ZNF628 MUTATED	3	1	1	0
ZNF628 WILD-TYPE	13	15	3	18

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0947 (Fisher's exact test), Q value = 1

Table S379. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ZNF628 MUTATED	1	3	1
ZNF628 WILD-TYPE	25	8	17

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S380. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ZNF628 MUTATED	0	3	0	2	0
ZNF628 WILD-TYPE	13	15	8	12	2

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 1

Table S381. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ZNF628 MUTATED	1	3	1
ZNF628 WILD-TYPE	20	11	18

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S382. Gene #40: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ZNF628 MUTATED	2	2	1
ZNF628 WILD-TYPE	28	14	7

'BTBD11 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S383. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
BTBD11 MUTATED	2	2	1	1
BTBD11 WILD-TYPE	19	18	9	8

'BTBD11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S384. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
BTBD11 MUTATED	1	1	1	0	2
BTBD11 WILD-TYPE	12	7	13	13	5

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S385. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
BTBD11 MUTATED	1	0	3	1
BTBD11 WILD-TYPE	15	8	11	15

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S386. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
BTBD11 MUTATED	1	2	0	2
BTBD11 WILD-TYPE	15	14	4	16

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S387. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
BTBD11 MUTATED	4	0	1
BTBD11 WILD-TYPE	22	11	17

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.183 (Fisher's exact test), Q value = 1

Table S388. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
BTBD11 MUTATED	2	0	2	1	0
BTBD11 WILD-TYPE	11	18	6	13	2

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S389. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
BTBD11 MUTATED	3	1	1
BTBD11 WILD-TYPE	18	13	18

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S390. Gene #41: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
BTBD11 MUTATED	4	0	1
BTBD11 WILD-TYPE	26	16	7

'IRX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S391. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
IRX3 MUTATED	3	0	2	0
IRX3 WILD-TYPE	18	20	8	9

'IRX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S392. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
IRX3 MUTATED	0	1	2	1	0
IRX3 WILD-TYPE	13	7	12	12	7

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S393. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
IRX3 MUTATED	2	1	1	0
IRX3 WILD-TYPE	14	7	13	16

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S394. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
IRX3 MUTATED	1	2	1	0
IRX3 WILD-TYPE	15	14	3	18

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S395. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
IRX3 MUTATED	2	2	0
IRX3 WILD-TYPE	24	9	18

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S396. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
IRX3 MUTATED	2	1	0	1	0
IRX3 WILD-TYPE	11	17	8	13	2

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S397. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
IRX3 MUTATED	3	1	0
IRX3 WILD-TYPE	18	13	19

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S398. Gene #42: 'IRX3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
IRX3 MUTATED	3	0	1
IRX3 WILD-TYPE	27	16	7

'FPGS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S399. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
FPGS MUTATED	2	2	1	0
FPGS WILD-TYPE	19	18	9	9

'FPGS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S400. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
FPGS MUTATED	1	1	1	1	0
FPGS WILD-TYPE	12	7	13	12	7

'FPGS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S401. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
FPGS MUTATED	2	0	1	0
FPGS WILD-TYPE	6	8	5	6

'FPGS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S402. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
FPGS MUTATED	1	1	0	0	0	1	0	0
FPGS WILD-TYPE	4	5	5	3	3	0	3	2

'FPGS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S403. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
FPGS MUTATED	1	1	0	2
FPGS WILD-TYPE	15	7	14	14

'FPGS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S404. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FPGS MUTATED	2	0	0	2
FPGS WILD-TYPE	14	16	4	16

'FPGS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0553 (Fisher's exact test), Q value = 1

Table S405. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
FPGS MUTATED	0	2	2
FPGS WILD-TYPE	26	9	16

'FPGS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S406. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FPGS MUTATED	0	2	0	2	0
FPGS WILD-TYPE	13	16	8	12	2

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S407. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
FPGS MUTATED	1	1	2
FPGS WILD-TYPE	20	13	17

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S408. Gene #43: 'FPGS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
FPGS MUTATED	2	2	0
FPGS WILD-TYPE	28	14	8

'MEN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S409. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MEN1 MUTATED	1	1	2	0
MEN1 WILD-TYPE	20	19	8	9

'MEN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0487 (Fisher's exact test), Q value = 1

Table S410. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MEN1 MUTATED	0	1	4	0	0
MEN1 WILD-TYPE	13	7	10	13	7

Figure S22. Get High-res Image Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0131 (Fisher's exact test), Q value = 1

Table S411. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MEN1 MUTATED	0	1	4	0
MEN1 WILD-TYPE	16	7	10	16

Figure S23. Get High-res Image Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00683 (Fisher's exact test), Q value = 1

Table S412. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MEN1 MUTATED	0	5	0	0
MEN1 WILD-TYPE	16	11	4	18

Figure S24. Get High-res Image Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.206 (Fisher's exact test), Q value = 1

Table S413. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MEN1 MUTATED	4	1	0
MEN1 WILD-TYPE	22	10	18

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0426 (Fisher's exact test), Q value = 1

Table S414. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MEN1 MUTATED	4	0	0	1	0
MEN1 WILD-TYPE	9	18	8	13	2

Figure S25. Get High-res Image Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.136 (Fisher's exact test), Q value = 1

Table S415. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MEN1 MUTATED	4	1	0
MEN1 WILD-TYPE	17	13	19

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S416. Gene #44: 'MEN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MEN1 MUTATED	5	0	0
MEN1 WILD-TYPE	25	16	8

'BHLHE22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S417. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
BHLHE22 MUTATED	1	2	2	0
BHLHE22 WILD-TYPE	20	18	8	9

'BHLHE22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0719 (Fisher's exact test), Q value = 1

Table S418. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
BHLHE22 MUTATED	0	3	1	1	0
BHLHE22 WILD-TYPE	13	5	13	12	7

'BHLHE22 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.889 (Fisher's exact test), Q value = 1

Table S419. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
BHLHE22 MUTATED	2	1	0	1
BHLHE22 WILD-TYPE	6	7	6	5

'BHLHE22 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S420. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
BHLHE22 MUTATED	2	1	1	0	0	0	0	0
BHLHE22 WILD-TYPE	3	5	4	3	3	1	3	2

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S421. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
BHLHE22 MUTATED	0	2	2	1
BHLHE22 WILD-TYPE	16	6	12	15

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S422. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
BHLHE22 MUTATED	2	2	0	1
BHLHE22 WILD-TYPE	14	14	4	17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S423. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
BHLHE22 MUTATED	2	2	1
BHLHE22 WILD-TYPE	24	9	17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S424. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
BHLHE22 MUTATED	2	2	0	1	0
BHLHE22 WILD-TYPE	11	16	8	13	2

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S425. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
BHLHE22 MUTATED	3	1	1
BHLHE22 WILD-TYPE	18	13	18

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S426. Gene #45: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
BHLHE22 MUTATED	3	2	0
BHLHE22 WILD-TYPE	27	14	8

'DMKN MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S427. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
DMKN MUTATED	2	1	0	0
DMKN WILD-TYPE	19	19	10	9

'DMKN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S428. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
DMKN MUTATED	0	1	2	0	0
DMKN WILD-TYPE	13	7	12	13	7

'DMKN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S429. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
DMKN MUTATED	1	1	1	0
DMKN WILD-TYPE	15	7	13	16

'DMKN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S430. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
DMKN MUTATED	1	2	0	0
DMKN WILD-TYPE	15	14	4	18

'DMKN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00622 (Fisher's exact test), Q value = 1

Table S431. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
DMKN MUTATED	0	3	0
DMKN WILD-TYPE	26	8	18

Figure S26. Get High-res Image Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S432. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
DMKN MUTATED	0	1	0	2	0
DMKN WILD-TYPE	13	17	8	12	2

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S433. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
DMKN MUTATED	1	2	0
DMKN WILD-TYPE	20	12	19

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S434. Gene #46: 'DMKN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
DMKN MUTATED	2	1	0
DMKN WILD-TYPE	28	15	8

'OBSCN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 1

Table S435. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
OBSCN MUTATED	9	6	1	2
OBSCN WILD-TYPE	12	14	9	7

'OBSCN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S436. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
OBSCN MUTATED	4	4	2	4	2
OBSCN WILD-TYPE	9	4	12	9	5

'OBSCN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S437. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
OBSCN MUTATED	2	2	2	2
OBSCN WILD-TYPE	6	6	4	4

'OBSCN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S438. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
OBSCN MUTATED	1	2	1	0	2	0	2	0
OBSCN WILD-TYPE	4	4	4	3	1	1	1	2

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S439. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
OBSCN MUTATED	6	2	5	3
OBSCN WILD-TYPE	10	6	9	13

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S440. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
OBSCN MUTATED	5	4	2	5
OBSCN WILD-TYPE	11	12	2	13

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 1

Table S441. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
OBSCN MUTATED	6	6	4
OBSCN WILD-TYPE	20	5	14

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S442. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
OBSCN MUTATED	2	5	3	6	0
OBSCN WILD-TYPE	11	13	5	8	2

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S443. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
OBSCN MUTATED	6	4	6
OBSCN WILD-TYPE	15	10	13

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.386 (Fisher's exact test), Q value = 1

Table S444. Gene #47: 'OBSCN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
OBSCN MUTATED	8	4	4
OBSCN WILD-TYPE	22	12	4

'PANK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S445. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PANK2 MUTATED	3	1	0	1
PANK2 WILD-TYPE	18	19	10	8

'PANK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S446. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PANK2 MUTATED	2	0	0	1	0
PANK2 WILD-TYPE	11	8	14	12	7

'PANK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S447. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
PANK2 MUTATED	2	0	0	1
PANK2 WILD-TYPE	6	8	6	5

'PANK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S448. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PANK2 MUTATED	2	0	0	0	1	0	0	0
PANK2 WILD-TYPE	3	6	5	3	2	1	3	2

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S449. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PANK2 MUTATED	3	0	0	0
PANK2 WILD-TYPE	13	8	14	16

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.052 (Fisher's exact test), Q value = 1

Table S450. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PANK2 MUTATED	2	0	1	0
PANK2 WILD-TYPE	14	16	3	18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S451. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PANK2 MUTATED	2	1	0
PANK2 WILD-TYPE	24	10	18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S452. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PANK2 MUTATED	1	0	0	2	0
PANK2 WILD-TYPE	12	18	8	12	2

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S453. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PANK2 MUTATED	1	1	1
PANK2 WILD-TYPE	20	13	18

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.255 (Fisher's exact test), Q value = 1

Table S454. Gene #48: 'PANK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PANK2 MUTATED	2	0	1
PANK2 WILD-TYPE	28	16	7

'RREB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S455. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RREB1 MUTATED	3	1	1	0
RREB1 WILD-TYPE	18	19	9	9

'RREB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S456. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RREB1 MUTATED	2	0	1	1	0
RREB1 WILD-TYPE	11	8	13	12	7

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.619 (Fisher's exact test), Q value = 1

Table S457. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RREB1 MUTATED	1	1	1	0
RREB1 WILD-TYPE	15	7	13	16

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S458. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RREB1 MUTATED	1	1	0	1
RREB1 WILD-TYPE	15	15	4	17

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S459. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RREB1 MUTATED	1	1	2
RREB1 WILD-TYPE	25	10	16

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S460. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RREB1 MUTATED	2	2	0	0	0
RREB1 WILD-TYPE	11	16	8	14	2

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S461. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RREB1 MUTATED	0	2	2
RREB1 WILD-TYPE	21	12	17

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S462. Gene #49: 'RREB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RREB1 MUTATED	1	2	1
RREB1 WILD-TYPE	29	14	7

'RNF149 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S463. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RNF149 MUTATED	0	2	1	1
RNF149 WILD-TYPE	21	18	9	8

'RNF149 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0367 (Fisher's exact test), Q value = 1

Table S464. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RNF149 MUTATED	0	0	2	0	2
RNF149 WILD-TYPE	13	8	12	13	5

Figure S27. Get High-res Image Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'RNF149 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S465. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
RNF149 MUTATED	0	1	1	1
RNF149 WILD-TYPE	8	7	5	5

'RNF149 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S466. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RNF149 MUTATED	0	1	1	0	1	0	0	0
RNF149 WILD-TYPE	5	5	4	3	2	1	3	2

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S467. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RNF149 MUTATED	0	1	2	1
RNF149 WILD-TYPE	16	7	12	15

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S468. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RNF149 MUTATED	0	2	0	2
RNF149 WILD-TYPE	16	14	4	16

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.318 (Fisher's exact test), Q value = 1

Table S469. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RNF149 MUTATED	1	2	1
RNF149 WILD-TYPE	25	9	17

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 1

Table S470. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RNF149 MUTATED	0	3	1	0	0
RNF149 WILD-TYPE	13	15	7	14	2

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S471. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RNF149 MUTATED	1	2	1
RNF149 WILD-TYPE	20	12	18

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S472. Gene #50: 'RNF149 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RNF149 MUTATED	1	3	0
RNF149 WILD-TYPE	29	13	8

'GLTPD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S473. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
GLTPD2 MUTATED	3	1	1	1
GLTPD2 WILD-TYPE	18	19	9	8

'GLTPD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S474. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
GLTPD2 MUTATED	1	0	2	2	1
GLTPD2 WILD-TYPE	12	8	12	11	6

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S475. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
GLTPD2 MUTATED	2	0	2	2
GLTPD2 WILD-TYPE	14	8	12	14

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S476. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GLTPD2 MUTATED	1	3	1	1
GLTPD2 WILD-TYPE	15	13	3	17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S477. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
GLTPD2 MUTATED	3	2	1
GLTPD2 WILD-TYPE	23	9	17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.531 (Fisher's exact test), Q value = 1

Table S478. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GLTPD2 MUTATED	2	1	0	3	0
GLTPD2 WILD-TYPE	11	17	8	11	2

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S479. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
GLTPD2 MUTATED	3	1	2
GLTPD2 WILD-TYPE	18	13	17

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S480. Gene #51: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
GLTPD2 MUTATED	4	0	2
GLTPD2 WILD-TYPE	26	16	6

'SNED1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S481. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SNED1 MUTATED	3	1	0	1
SNED1 WILD-TYPE	18	19	10	8

'SNED1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S482. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SNED1 MUTATED	2	2	1	0	0
SNED1 WILD-TYPE	11	6	13	13	7

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S483. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SNED1 MUTATED	3	1	0	1
SNED1 WILD-TYPE	13	7	14	15

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S484. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SNED1 MUTATED	3	1	0	1
SNED1 WILD-TYPE	13	15	4	17

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0943 (Fisher's exact test), Q value = 1

Table S485. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SNED1 MUTATED	1	3	1
SNED1 WILD-TYPE	25	8	17

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S486. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SNED1 MUTATED	0	2	1	2	0
SNED1 WILD-TYPE	13	16	7	12	2

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S487. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SNED1 MUTATED	2	1	2
SNED1 WILD-TYPE	19	13	17

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S488. Gene #52: 'SNED1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SNED1 MUTATED	2	2	1
SNED1 WILD-TYPE	28	14	7

'TPO MUTATION STATUS' versus 'CN_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 1

Table S489. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TPO MUTATED	7	2	1	2
TPO WILD-TYPE	14	18	9	7

'TPO MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S490. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TPO MUTATED	3	3	1	2	0
TPO WILD-TYPE	10	5	13	11	7

'TPO MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S491. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
TPO MUTATED	2	1	0	1
TPO WILD-TYPE	6	7	6	5

'TPO MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S492. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TPO MUTATED	2	1	0	0	1	0	0	0
TPO WILD-TYPE	3	5	5	3	2	1	3	2

'TPO MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S493. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TPO MUTATED	5	2	1	1
TPO WILD-TYPE	11	6	13	15

'TPO MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S494. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TPO MUTATED	4	2	2	1
TPO WILD-TYPE	12	14	2	17

'TPO MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0981 (Fisher's exact test), Q value = 1

Table S495. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TPO MUTATED	4	4	1
TPO WILD-TYPE	22	7	17

'TPO MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S496. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TPO MUTATED	1	2	1	5	0
TPO WILD-TYPE	12	16	7	9	2

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S497. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TPO MUTATED	4	2	3
TPO WILD-TYPE	17	12	16

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.17 (Fisher's exact test), Q value = 1

Table S498. Gene #53: 'TPO MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TPO MUTATED	5	1	3
TPO WILD-TYPE	25	15	5

'PTPLA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S499. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PTPLA MUTATED	2	0	1	1
PTPLA WILD-TYPE	19	20	9	8

'PTPLA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S500. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PTPLA MUTATED	0	1	2	0	0
PTPLA WILD-TYPE	13	7	12	13	7

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S501. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PTPLA MUTATED	1	0	2	0
PTPLA WILD-TYPE	15	8	12	16

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S502. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PTPLA MUTATED	1	2	0	0
PTPLA WILD-TYPE	15	14	4	18

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S503. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PTPLA MUTATED	1	1	1
PTPLA WILD-TYPE	25	10	17

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S504. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PTPLA MUTATED	1	1	0	1	0
PTPLA WILD-TYPE	12	17	8	13	2

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S505. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PTPLA MUTATED	2	0	1
PTPLA WILD-TYPE	19	14	18

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S506. Gene #54: 'PTPLA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PTPLA MUTATED	2	1	0
PTPLA WILD-TYPE	28	15	8

'PRSS27 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S507. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PRSS27 MUTATED	1	1	1	0
PRSS27 WILD-TYPE	20	19	9	9

'PRSS27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.91 (Fisher's exact test), Q value = 1

Table S508. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PRSS27 MUTATED	0	1	1	1	0
PRSS27 WILD-TYPE	13	7	13	12	7

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.619 (Fisher's exact test), Q value = 1

Table S509. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PRSS27 MUTATED	1	1	1	0
PRSS27 WILD-TYPE	15	7	13	16

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0506 (Fisher's exact test), Q value = 1

Table S510. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PRSS27 MUTATED	0	2	1	0
PRSS27 WILD-TYPE	16	14	3	18

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 1

Table S511. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PRSS27 MUTATED	1	2	0
PRSS27 WILD-TYPE	25	9	18

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S512. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PRSS27 MUTATED	1	1	0	1	0
PRSS27 WILD-TYPE	12	17	8	13	2

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S513. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PRSS27 MUTATED	1	0	2
PRSS27 WILD-TYPE	20	14	17

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S514. Gene #55: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PRSS27 MUTATED	1	1	1
PRSS27 WILD-TYPE	29	15	7

'CD320 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S515. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CD320 MUTATED	2	1	1	0
CD320 WILD-TYPE	19	19	9	9

'CD320 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S516. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CD320 MUTATED	1	0	1	2	0
CD320 WILD-TYPE	12	8	13	11	7

'CD320 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S517. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CD320 MUTATED	1	0	2	1
CD320 WILD-TYPE	15	8	12	15

'CD320 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.659 (Fisher's exact test), Q value = 1

Table S518. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CD320 MUTATED	1	1	1	1
CD320 WILD-TYPE	15	15	3	17

'CD320 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S519. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CD320 MUTATED	3	1	0
CD320 WILD-TYPE	23	10	18

'CD320 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S520. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CD320 MUTATED	1	0	2	1	0
CD320 WILD-TYPE	12	18	6	13	2

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S521. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CD320 MUTATED	3	1	0
CD320 WILD-TYPE	18	13	19

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S522. Gene #56: 'CD320 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CD320 MUTATED	4	0	0
CD320 WILD-TYPE	26	16	8

'SEMA5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S523. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SEMA5B MUTATED	5	2	0	1
SEMA5B WILD-TYPE	16	18	10	8

'SEMA5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 1

Table S524. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SEMA5B MUTATED	2	1	0	3	0
SEMA5B WILD-TYPE	11	7	14	10	7

'SEMA5B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S525. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
SEMA5B MUTATED	2	0	1	1
SEMA5B WILD-TYPE	6	8	5	5

'SEMA5B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S526. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SEMA5B MUTATED	2	0	1	0	0	1	0	0
SEMA5B WILD-TYPE	3	6	4	3	3	0	3	2

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.397 (Fisher's exact test), Q value = 1

Table S527. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SEMA5B MUTATED	3	1	0	2
SEMA5B WILD-TYPE	13	7	14	14

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S528. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SEMA5B MUTATED	3	0	1	2
SEMA5B WILD-TYPE	13	16	3	16

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S529. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SEMA5B MUTATED	2	2	2
SEMA5B WILD-TYPE	24	9	16

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S530. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SEMA5B MUTATED	0	4	0	2	0
SEMA5B WILD-TYPE	13	14	8	12	2

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S531. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SEMA5B MUTATED	1	3	2
SEMA5B WILD-TYPE	20	11	17

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.408 (Fisher's exact test), Q value = 1

Table S532. Gene #57: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SEMA5B MUTATED	2	3	1
SEMA5B WILD-TYPE	28	13	7

'CCDC150 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.18 (Fisher's exact test), Q value = 1

Table S533. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CCDC150 MUTATED	2	0	2	0
CCDC150 WILD-TYPE	19	20	8	9

'CCDC150 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S534. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CCDC150 MUTATED	2	0	1	1	0
CCDC150 WILD-TYPE	11	8	13	12	7

'CCDC150 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S535. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
CCDC150 MUTATED	1	1	0	1
CCDC150 WILD-TYPE	7	7	6	5

'CCDC150 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S536. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CCDC150 MUTATED	0	1	0	1	1	0	0	0
CCDC150 WILD-TYPE	5	5	5	2	2	1	3	2

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 1

Table S537. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CCDC150 MUTATED	3	0	1	0
CCDC150 WILD-TYPE	13	8	13	16

'CCDC150 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S538. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CCDC150 MUTATED	2	1	1	0
CCDC150 WILD-TYPE	14	15	3	18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S539. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CCDC150 MUTATED	3	1	0
CCDC150 WILD-TYPE	23	10	18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S540. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CCDC150 MUTATED	1	0	0	3	0
CCDC150 WILD-TYPE	12	18	8	11	2

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S541. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CCDC150 MUTATED	2	1	1
CCDC150 WILD-TYPE	19	13	18

'CCDC150 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S542. Gene #58: 'CCDC150 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CCDC150 MUTATED	3	0	1
CCDC150 WILD-TYPE	27	16	7

'TAF5 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S543. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TAF5 MUTATED	2	1	1	0
TAF5 WILD-TYPE	19	19	9	9

'TAF5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S544. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TAF5 MUTATED	1	1	1	0	1
TAF5 WILD-TYPE	12	7	13	13	6

'TAF5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S545. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
TAF5 MUTATED	1	1	0	1
TAF5 WILD-TYPE	7	7	6	5

'TAF5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.953 (Fisher's exact test), Q value = 1

Table S546. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
TAF5 MUTATED	1	1	0	0	1	0	0	0
TAF5 WILD-TYPE	4	5	5	3	2	1	3	2

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S547. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TAF5 MUTATED	1	1	1	1
TAF5 WILD-TYPE	15	7	13	15

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S548. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TAF5 MUTATED	2	1	0	1
TAF5 WILD-TYPE	14	15	4	17

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00926 (Fisher's exact test), Q value = 1

Table S549. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TAF5 MUTATED	0	3	1
TAF5 WILD-TYPE	26	8	17

Figure S28. Get High-res Image Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S550. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TAF5 MUTATED	0	4	0	0	0
TAF5 WILD-TYPE	13	14	8	14	2

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0555 (Fisher's exact test), Q value = 1

Table S551. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TAF5 MUTATED	0	3	1
TAF5 WILD-TYPE	21	11	18

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0141 (Fisher's exact test), Q value = 1

Table S552. Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TAF5 MUTATED	0	4	0
TAF5 WILD-TYPE	30	12	8

Figure S29. Get High-res Image Gene #59: 'TAF5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0754 (Fisher's exact test), Q value = 1

Table S553. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
GARS MUTATED	5	4	4	6
GARS WILD-TYPE	16	16	6	3

'GARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0922 (Fisher's exact test), Q value = 1

Table S554. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
GARS MUTATED	2	0	4	5	4
GARS WILD-TYPE	11	8	10	8	3

'GARS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S555. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
GARS MUTATED	2	1	3	3
GARS WILD-TYPE	6	7	3	3

'GARS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S556. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
GARS MUTATED	2	1	4	1	0	0	1	0
GARS WILD-TYPE	3	5	1	2	3	1	2	2

'GARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S557. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
GARS MUTATED	3	1	4	7
GARS WILD-TYPE	13	7	10	9

'GARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 1

Table S558. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
GARS MUTATED	2	3	2	8
GARS WILD-TYPE	14	13	2	10

'GARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S559. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
GARS MUTATED	6	1	8
GARS WILD-TYPE	20	10	10

'GARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S560. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
GARS MUTATED	3	6	4	2	0
GARS WILD-TYPE	10	12	4	12	2

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S561. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
GARS MUTATED	5	2	8
GARS WILD-TYPE	16	12	11

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S562. Gene #60: 'GARS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
GARS MUTATED	6	6	3
GARS WILD-TYPE	24	10	5

'MUC5B MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S563. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MUC5B MUTATED	8	7	3	3
MUC5B WILD-TYPE	13	13	7	6

'MUC5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S564. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MUC5B MUTATED	3	3	6	4	4
MUC5B WILD-TYPE	10	5	8	9	3

'MUC5B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.53 (Fisher's exact test), Q value = 1

Table S565. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
MUC5B MUTATED	2	3	4	2
MUC5B WILD-TYPE	6	5	2	4

'MUC5B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.809 (Fisher's exact test), Q value = 1

Table S566. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
MUC5B MUTATED	2	2	2	0	2	0	2	1
MUC5B WILD-TYPE	3	4	3	3	1	1	1	1

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S567. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MUC5B MUTATED	5	3	7	5
MUC5B WILD-TYPE	11	5	7	11

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S568. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MUC5B MUTATED	4	7	2	7
MUC5B WILD-TYPE	12	9	2	11

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S569. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MUC5B MUTATED	8	5	7
MUC5B WILD-TYPE	18	6	11

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S570. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MUC5B MUTATED	3	7	4	6	0
MUC5B WILD-TYPE	10	11	4	8	2

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S571. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MUC5B MUTATED	7	5	7
MUC5B WILD-TYPE	14	9	12

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.531 (Fisher's exact test), Q value = 1

Table S572. Gene #61: 'MUC5B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MUC5B MUTATED	9	6	4
MUC5B WILD-TYPE	21	10	4

'KIAA1984 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S573. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KIAA1984 MUTATED	2	0	1	1
KIAA1984 WILD-TYPE	19	20	9	8

'KIAA1984 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S574. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KIAA1984 MUTATED	0	1	2	1	0
KIAA1984 WILD-TYPE	13	7	12	12	7

'KIAA1984 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S575. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
KIAA1984 MUTATED	0	2	0	1
KIAA1984 WILD-TYPE	8	6	6	5

'KIAA1984 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S576. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KIAA1984 MUTATED	0	2	0	0	1	0	0	0
KIAA1984 WILD-TYPE	5	4	5	3	2	1	3	2

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.127 (Fisher's exact test), Q value = 1

Table S577. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KIAA1984 MUTATED	1	0	3	0
KIAA1984 WILD-TYPE	15	8	11	16

'KIAA1984 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0493 (Fisher's exact test), Q value = 1

Table S578. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KIAA1984 MUTATED	0	3	1	0
KIAA1984 WILD-TYPE	16	13	3	18

Figure S30. Get High-res Image Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0313 (Fisher's exact test), Q value = 1

Table S579. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KIAA1984 MUTATED	1	3	0
KIAA1984 WILD-TYPE	25	8	18

Figure S31. Get High-res Image Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S580. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KIAA1984 MUTATED	0	1	1	2	0
KIAA1984 WILD-TYPE	13	17	7	12	2

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S581. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KIAA1984 MUTATED	1	2	1
KIAA1984 WILD-TYPE	20	12	18

'KIAA1984 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S582. Gene #62: 'KIAA1984 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KIAA1984 MUTATED	2	1	1
KIAA1984 WILD-TYPE	28	15	7

'SRPX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.753 (Fisher's exact test), Q value = 1

Table S583. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SRPX MUTATED	1	2	0	0
SRPX WILD-TYPE	20	18	10	9

'SRPX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 1

Table S584. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SRPX MUTATED	0	2	0	1	0
SRPX WILD-TYPE	13	6	14	12	7

'SRPX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S585. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SRPX MUTATED	0	1	1	1
SRPX WILD-TYPE	16	7	13	15

'SRPX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S586. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SRPX MUTATED	1	1	0	1
SRPX WILD-TYPE	15	15	4	17

'SRPX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S587. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SRPX MUTATED	1	1	1
SRPX WILD-TYPE	25	10	17

'SRPX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.718 (Fisher's exact test), Q value = 1

Table S588. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SRPX MUTATED	1	2	0	0	0
SRPX WILD-TYPE	12	16	8	14	2

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S589. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SRPX MUTATED	1	1	1
SRPX WILD-TYPE	20	13	18

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S590. Gene #63: 'SRPX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SRPX MUTATED	1	2	0
SRPX WILD-TYPE	29	14	8

'TNIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S591. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TNIP2 MUTATED	3	1	0	1
TNIP2 WILD-TYPE	18	19	10	8

'TNIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S592. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
TNIP2 MUTATED	1	1	2	0	0
TNIP2 WILD-TYPE	12	7	12	13	7

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S593. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
TNIP2 MUTATED	1	0	2	1
TNIP2 WILD-TYPE	15	8	12	15

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S594. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
TNIP2 MUTATED	1	2	0	1
TNIP2 WILD-TYPE	15	14	4	17

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S595. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
TNIP2 MUTATED	2	1	1
TNIP2 WILD-TYPE	24	10	17

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S596. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
TNIP2 MUTATED	1	0	1	2	0
TNIP2 WILD-TYPE	12	18	7	12	2

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S597. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
TNIP2 MUTATED	2	1	1
TNIP2 WILD-TYPE	19	13	18

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S598. Gene #64: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
TNIP2 MUTATED	3	0	1
TNIP2 WILD-TYPE	27	16	7

'IDUA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S599. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
IDUA MUTATED	5	1	1	1
IDUA WILD-TYPE	16	19	9	8

'IDUA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S600. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
IDUA MUTATED	2	1	3	1	0
IDUA WILD-TYPE	11	7	11	12	7

'IDUA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S601. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
IDUA MUTATED	1	1	0	2
IDUA WILD-TYPE	7	7	6	4

'IDUA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S602. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
IDUA MUTATED	1	0	1	1	1	0	0	0
IDUA WILD-TYPE	4	6	4	2	2	1	3	2

'IDUA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S603. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
IDUA MUTATED	3	2	1	1
IDUA WILD-TYPE	13	6	13	15

'IDUA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S604. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
IDUA MUTATED	3	3	0	1
IDUA WILD-TYPE	13	13	4	17

'IDUA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 1

Table S605. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
IDUA MUTATED	3	3	1
IDUA WILD-TYPE	23	8	17

'IDUA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S606. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
IDUA MUTATED	1	2	0	4	0
IDUA WILD-TYPE	12	16	8	10	2

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S607. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
IDUA MUTATED	4	2	1
IDUA WILD-TYPE	17	12	18

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S608. Gene #65: 'IDUA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
IDUA MUTATED	5	2	0
IDUA WILD-TYPE	25	14	8

'RNF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.726 (Fisher's exact test), Q value = 1

Table S609. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RNF39 MUTATED	3	1	1	0
RNF39 WILD-TYPE	18	19	9	9

'RNF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S610. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RNF39 MUTATED	1	2	2	0	0
RNF39 WILD-TYPE	12	6	12	13	7

'RNF39 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 1

Table S611. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
RNF39 MUTATED	1	3	0	0
RNF39 WILD-TYPE	7	5	6	6

'RNF39 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S612. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
RNF39 MUTATED	1	2	0	1	0	0	0	0
RNF39 WILD-TYPE	4	4	5	2	3	1	3	2

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S613. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RNF39 MUTATED	1	1	3	0
RNF39 WILD-TYPE	15	7	11	16

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.266 (Fisher's exact test), Q value = 1

Table S614. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RNF39 MUTATED	2	3	0	0
RNF39 WILD-TYPE	14	13	4	18

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 1

Table S615. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RNF39 MUTATED	3	2	0
RNF39 WILD-TYPE	23	9	18

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S616. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RNF39 MUTATED	2	1	0	2	0
RNF39 WILD-TYPE	11	17	8	12	2

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S617. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RNF39 MUTATED	3	2	0
RNF39 WILD-TYPE	18	12	19

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S618. Gene #66: 'RNF39 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RNF39 MUTATED	4	1	0
RNF39 WILD-TYPE	26	15	8

'PABPC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S619. Gene #67: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PABPC1 MUTATED	1	1	2	0
PABPC1 WILD-TYPE	20	19	8	9

'SCRT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S620. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SCRT1 MUTATED	2	1	0	0
SCRT1 WILD-TYPE	19	19	10	9

'SCRT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S621. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SCRT1 MUTATED	2	0	0	1	0
SCRT1 WILD-TYPE	11	8	14	12	7

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S622. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SCRT1 MUTATED	2	0	1	0
SCRT1 WILD-TYPE	14	8	13	16

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S623. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SCRT1 MUTATED	2	0	0	1
SCRT1 WILD-TYPE	14	16	4	17

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S624. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SCRT1 MUTATED	2	1	0
SCRT1 WILD-TYPE	24	10	18

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S625. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SCRT1 MUTATED	0	1	1	1	0
SCRT1 WILD-TYPE	13	17	7	13	2

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S626. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SCRT1 MUTATED	2	1	0
SCRT1 WILD-TYPE	19	13	19

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S627. Gene #68: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SCRT1 MUTATED	2	1	0
SCRT1 WILD-TYPE	28	15	8

'MAP1S MUTATION STATUS' versus 'CN_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 1

Table S628. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MAP1S MUTATED	0	2	1	2
MAP1S WILD-TYPE	21	18	9	7

'MAP1S MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S629. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MAP1S MUTATED	1	1	0	3	0
MAP1S WILD-TYPE	12	7	14	10	7

'MAP1S MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S630. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
MAP1S MUTATED	2	0	0	2
MAP1S WILD-TYPE	6	8	6	4

'MAP1S MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.42 (Fisher's exact test), Q value = 1

Table S631. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
MAP1S MUTATED	2	0	2	0	0	0	0	0
MAP1S WILD-TYPE	3	6	3	3	3	1	3	2

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S632. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MAP1S MUTATED	1	1	0	3
MAP1S WILD-TYPE	15	7	14	13

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S633. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MAP1S MUTATED	2	1	0	2
MAP1S WILD-TYPE	14	15	4	16

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S634. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MAP1S MUTATED	2	1	2
MAP1S WILD-TYPE	24	10	16

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.835 (Fisher's exact test), Q value = 1

Table S635. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MAP1S MUTATED	2	2	0	1	0
MAP1S WILD-TYPE	11	16	8	13	2

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.42 (Fisher's exact test), Q value = 1

Table S636. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MAP1S MUTATED	3	0	2
MAP1S WILD-TYPE	18	14	17

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S637. Gene #69: 'MAP1S MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MAP1S MUTATED	3	2	0
MAP1S WILD-TYPE	27	14	8

'NF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S638. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NF1 MUTATED	4	1	0	2
NF1 WILD-TYPE	17	19	10	7

'NF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S639. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NF1 MUTATED	2	0	2	2	1
NF1 WILD-TYPE	11	8	12	11	6

'NF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.889 (Fisher's exact test), Q value = 1

Table S640. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
NF1 MUTATED	1	2	0	1
NF1 WILD-TYPE	7	6	6	5

'NF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S641. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
NF1 MUTATED	1	0	0	1	1	0	0	1
NF1 WILD-TYPE	4	6	5	2	2	1	3	1

'NF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S642. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NF1 MUTATED	4	0	2	1
NF1 WILD-TYPE	12	8	12	15

'NF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 1

Table S643. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NF1 MUTATED	2	2	2	1
NF1 WILD-TYPE	14	14	2	17

'NF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.282 (Fisher's exact test), Q value = 1

Table S644. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NF1 MUTATED	2	3	2
NF1 WILD-TYPE	24	8	16

'NF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S645. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NF1 MUTATED	1	2	1	3	0
NF1 WILD-TYPE	12	16	7	11	2

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S646. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NF1 MUTATED	3	2	2
NF1 WILD-TYPE	18	12	17

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0966 (Fisher's exact test), Q value = 1

Table S647. Gene #70: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NF1 MUTATED	3	1	3
NF1 WILD-TYPE	27	15	5

'AKAP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S648. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AKAP2 MUTATED	1	0	1	2
AKAP2 WILD-TYPE	20	20	9	7

'AKAP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S649. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
AKAP2 MUTATED	0	0	2	2	0
AKAP2 WILD-TYPE	13	8	12	11	7

'AKAP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S650. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
AKAP2 MUTATED	0	2	0	1
AKAP2 WILD-TYPE	8	6	6	5

'AKAP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S651. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
AKAP2 MUTATED	0	1	1	0	0	0	0	1
AKAP2 WILD-TYPE	5	5	4	3	3	1	3	1

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.74 (Fisher's exact test), Q value = 1

Table S652. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
AKAP2 MUTATED	1	0	2	1
AKAP2 WILD-TYPE	15	8	12	15

'AKAP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S653. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AKAP2 MUTATED	0	2	1	1
AKAP2 WILD-TYPE	16	14	3	17

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.527 (Fisher's exact test), Q value = 1

Table S654. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
AKAP2 MUTATED	1	1	2
AKAP2 WILD-TYPE	25	10	16

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S655. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AKAP2 MUTATED	1	3	0	0	0
AKAP2 WILD-TYPE	12	15	8	14	2

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S656. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
AKAP2 MUTATED	1	1	2
AKAP2 WILD-TYPE	20	13	17

'AKAP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S657. Gene #71: 'AKAP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
AKAP2 MUTATED	1	2	1
AKAP2 WILD-TYPE	29	14	7

'NOTCH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S658. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NOTCH2 MUTATED	4	1	0	0
NOTCH2 WILD-TYPE	17	19	10	9

'NOTCH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S659. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NOTCH2 MUTATED	1	0	2	1	0
NOTCH2 WILD-TYPE	12	8	12	12	7

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.524 (Fisher's exact test), Q value = 1

Table S660. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NOTCH2 MUTATED	2	1	1	0
NOTCH2 WILD-TYPE	14	7	13	16

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S661. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NOTCH2 MUTATED	1	2	1	0
NOTCH2 WILD-TYPE	15	14	3	18

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.031 (Fisher's exact test), Q value = 1

Table S662. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NOTCH2 MUTATED	1	3	0
NOTCH2 WILD-TYPE	25	8	18

Figure S32. Get High-res Image Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.318 (Fisher's exact test), Q value = 1

Table S663. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NOTCH2 MUTATED	0	1	0	3	0
NOTCH2 WILD-TYPE	13	17	8	11	2

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S664. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NOTCH2 MUTATED	1	2	1
NOTCH2 WILD-TYPE	20	12	18

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S665. Gene #72: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NOTCH2 MUTATED	2	1	1
NOTCH2 WILD-TYPE	28	15	7

'FANK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S666. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
FANK1 MUTATED	2	1	1	0
FANK1 WILD-TYPE	19	19	9	9

'FANK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.323 (Fisher's exact test), Q value = 1

Table S667. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
FANK1 MUTATED	0	1	0	1	1
FANK1 WILD-TYPE	13	7	14	12	6

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S668. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
FANK1 MUTATED	1	1	0	1
FANK1 WILD-TYPE	15	7	14	15

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S669. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FANK1 MUTATED	1	0	1	1
FANK1 WILD-TYPE	15	16	3	17

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S670. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
FANK1 MUTATED	1	1	1
FANK1 WILD-TYPE	25	10	17

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S671. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FANK1 MUTATED	0	0	1	2	0
FANK1 WILD-TYPE	13	18	7	12	2

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S672. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
FANK1 MUTATED	2	0	1
FANK1 WILD-TYPE	19	14	18

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S673. Gene #73: 'FANK1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
FANK1 MUTATED	2	0	1
FANK1 WILD-TYPE	28	16	7

'NEFH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0523 (Fisher's exact test), Q value = 1

Table S674. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NEFH MUTATED	5	0	1	0
NEFH WILD-TYPE	16	20	9	9

'NEFH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S675. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NEFH MUTATED	3	0	0	1	0
NEFH WILD-TYPE	10	8	14	12	7

'NEFH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 1

Table S676. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NEFH MUTATED	3	0	0	0
NEFH WILD-TYPE	13	8	14	16

'NEFH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0509 (Fisher's exact test), Q value = 1

Table S677. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NEFH MUTATED	2	0	1	0
NEFH WILD-TYPE	14	16	3	18

'NEFH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S678. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NEFH MUTATED	3	1	0
NEFH WILD-TYPE	23	10	18

'NEFH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S679. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NEFH MUTATED	1	0	0	3	0
NEFH WILD-TYPE	12	18	8	11	2

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S680. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NEFH MUTATED	1	2	1
NEFH WILD-TYPE	20	12	18

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S681. Gene #74: 'NEFH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NEFH MUTATED	3	0	1
NEFH WILD-TYPE	27	16	7

'NPTX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S682. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NPTX1 MUTATED	1	1	0	1
NPTX1 WILD-TYPE	20	19	10	8

'NPTX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S683. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NPTX1 MUTATED	1	0	1	1	0
NPTX1 WILD-TYPE	12	8	13	12	7

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S684. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NPTX1 MUTATED	1	0	1	1
NPTX1 WILD-TYPE	15	8	13	15

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S685. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NPTX1 MUTATED	1	0	0	2
NPTX1 WILD-TYPE	15	16	4	16

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S686. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NPTX1 MUTATED	1	0	2
NPTX1 WILD-TYPE	25	11	16

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S687. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NPTX1 MUTATED	0	1	1	1	0
NPTX1 WILD-TYPE	13	17	7	13	2

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S688. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NPTX1 MUTATED	0	1	2
NPTX1 WILD-TYPE	21	13	17

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S689. Gene #75: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NPTX1 MUTATED	1	1	1
NPTX1 WILD-TYPE	29	15	7

'KBTBD13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S690. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KBTBD13 MUTATED	5	3	0	1
KBTBD13 WILD-TYPE	16	17	10	8

'KBTBD13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S691. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KBTBD13 MUTATED	3	1	0	2	3
KBTBD13 WILD-TYPE	10	7	14	11	4

'KBTBD13 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S692. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
KBTBD13 MUTATED	1	1	1	1
KBTBD13 WILD-TYPE	7	7	5	5

'KBTBD13 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S693. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KBTBD13 MUTATED	1	0	1	1	1	0	0	0
KBTBD13 WILD-TYPE	4	6	4	2	2	1	3	2

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S694. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KBTBD13 MUTATED	4	1	1	3
KBTBD13 WILD-TYPE	12	7	13	13

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S695. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KBTBD13 MUTATED	4	0	1	4
KBTBD13 WILD-TYPE	12	16	3	14

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S696. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KBTBD13 MUTATED	4	2	3
KBTBD13 WILD-TYPE	22	9	15

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S697. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KBTBD13 MUTATED	0	4	2	3	0
KBTBD13 WILD-TYPE	13	14	6	11	2

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S698. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KBTBD13 MUTATED	4	2	3
KBTBD13 WILD-TYPE	17	12	16

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S699. Gene #76: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KBTBD13 MUTATED	4	4	1
KBTBD13 WILD-TYPE	26	12	7

'RASIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S700. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RASIP1 MUTATED	1	3	2	0
RASIP1 WILD-TYPE	20	17	8	9

'RASIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S701. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
RASIP1 MUTATED	2	2	2	0	0
RASIP1 WILD-TYPE	11	6	12	13	7

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0403 (Fisher's exact test), Q value = 1

Table S702. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
RASIP1 MUTATED	2	3	1	0
RASIP1 WILD-TYPE	14	5	13	16

Figure S33. Get High-res Image Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.188 (Fisher's exact test), Q value = 1

Table S703. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
RASIP1 MUTATED	3	3	0	0
RASIP1 WILD-TYPE	13	13	4	18

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0558 (Fisher's exact test), Q value = 1

Table S704. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
RASIP1 MUTATED	3	3	0
RASIP1 WILD-TYPE	23	8	18

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.7 (Fisher's exact test), Q value = 1

Table S705. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
RASIP1 MUTATED	1	2	0	3	0
RASIP1 WILD-TYPE	12	16	8	11	2

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S706. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
RASIP1 MUTATED	2	3	1
RASIP1 WILD-TYPE	19	11	18

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.712 (Fisher's exact test), Q value = 1

Table S707. Gene #77: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
RASIP1 MUTATED	4	2	0
RASIP1 WILD-TYPE	26	14	8

'AR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S708. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AR MUTATED	2	0	1	1
AR WILD-TYPE	19	20	9	8

'AR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S709. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
AR MUTATED	2	0	1	0	0
AR WILD-TYPE	11	8	13	13	7

'AR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S710. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
AR MUTATED	1	1	0	1
AR WILD-TYPE	7	7	6	5

'AR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S711. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
AR MUTATED	1	1	0	0	1	0	0	0
AR WILD-TYPE	4	5	5	3	2	1	3	2

'AR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S712. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
AR MUTATED	2	0	1	0
AR WILD-TYPE	14	8	13	16

'AR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S713. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AR MUTATED	2	1	0	0
AR WILD-TYPE	14	15	4	18

'AR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S714. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
AR MUTATED	2	1	0
AR WILD-TYPE	24	10	18

'AR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S715. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AR MUTATED	1	1	0	1	0
AR WILD-TYPE	12	17	8	13	2

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S716. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
AR MUTATED	1	2	0
AR WILD-TYPE	20	12	19

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S717. Gene #78: 'AR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
AR MUTATED	2	1	0
AR WILD-TYPE	28	15	8

'KNDC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S718. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KNDC1 MUTATED	1	4	2	2
KNDC1 WILD-TYPE	20	16	8	7

'KNDC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0666 (Fisher's exact test), Q value = 1

Table S719. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KNDC1 MUTATED	0	2	2	1	3
KNDC1 WILD-TYPE	13	6	12	12	4

'KNDC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S720. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
KNDC1 MUTATED	2	0	0	1
KNDC1 WILD-TYPE	6	8	6	5

'KNDC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S721. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
KNDC1 MUTATED	2	0	1	0	0	0	0	0
KNDC1 WILD-TYPE	3	6	4	3	3	1	3	2

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0255 (Fisher's exact test), Q value = 1

Table S722. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KNDC1 MUTATED	0	3	1	4
KNDC1 WILD-TYPE	16	5	13	12

Figure S34. Get High-res Image Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S723. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KNDC1 MUTATED	1	2	0	5
KNDC1 WILD-TYPE	15	14	4	13

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 1

Table S724. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KNDC1 MUTATED	2	2	4
KNDC1 WILD-TYPE	24	9	14

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.365 (Fisher's exact test), Q value = 1

Table S725. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KNDC1 MUTATED	1	3	3	1	0
KNDC1 WILD-TYPE	12	15	5	13	2

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.187 (Fisher's exact test), Q value = 1

Table S726. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KNDC1 MUTATED	4	0	4
KNDC1 WILD-TYPE	17	14	15

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.385 (Fisher's exact test), Q value = 1

Table S727. Gene #79: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KNDC1 MUTATED	3	3	2
KNDC1 WILD-TYPE	27	13	6

'SEZ6L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S728. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SEZ6L2 MUTATED	2	4	0	2
SEZ6L2 WILD-TYPE	19	16	10	7

'SEZ6L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S729. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SEZ6L2 MUTATED	2	2	1	1	0
SEZ6L2 WILD-TYPE	11	6	13	12	7

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S730. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
SEZ6L2 MUTATED	0	2	1	0
SEZ6L2 WILD-TYPE	8	6	5	6

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S731. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
SEZ6L2 MUTATED	0	2	1	0	0	0	0	0
SEZ6L2 WILD-TYPE	5	4	4	3	3	1	3	2

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S732. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SEZ6L2 MUTATED	2	0	2	2
SEZ6L2 WILD-TYPE	14	8	12	14

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S733. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SEZ6L2 MUTATED	2	2	0	2
SEZ6L2 WILD-TYPE	14	14	4	16

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S734. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SEZ6L2 MUTATED	4	0	2
SEZ6L2 WILD-TYPE	22	11	16

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S735. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SEZ6L2 MUTATED	1	1	2	2	0
SEZ6L2 WILD-TYPE	12	17	6	12	2

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S736. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SEZ6L2 MUTATED	2	2	2
SEZ6L2 WILD-TYPE	19	12	17

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S737. Gene #80: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SEZ6L2 MUTATED	4	1	1
SEZ6L2 WILD-TYPE	26	15	7

'VARS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S738. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
VARS MUTATED	2	2	1	1
VARS WILD-TYPE	19	18	9	8

'VARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S739. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
VARS MUTATED	0	1	3	2	0
VARS WILD-TYPE	13	7	11	11	7

'VARS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S740. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
VARS MUTATED	0	2	0	1
VARS WILD-TYPE	8	6	6	5

'VARS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.386 (Fisher's exact test), Q value = 1

Table S741. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
VARS MUTATED	0	1	0	0	1	0	0	1
VARS WILD-TYPE	5	5	5	3	2	1	3	1

'VARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S742. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
VARS MUTATED	1	0	4	1
VARS WILD-TYPE	15	8	10	15

'VARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.066 (Fisher's exact test), Q value = 1

Table S743. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
VARS MUTATED	0	4	1	1
VARS WILD-TYPE	16	12	3	17

'VARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S744. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
VARS MUTATED	2	2	2
VARS WILD-TYPE	24	9	16

'VARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S745. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
VARS MUTATED	2	2	0	2	0
VARS WILD-TYPE	11	16	8	12	2

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S746. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
VARS MUTATED	2	1	3
VARS WILD-TYPE	19	13	16

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S747. Gene #81: 'VARS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
VARS MUTATED	3	2	1
VARS WILD-TYPE	27	14	7

'IER5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 1

Table S748. Gene #82: 'IER5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
IER5 MUTATED	3	0	0	0
IER5 WILD-TYPE	18	20	10	9

'NMU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S749. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NMU MUTATED	1	2	1	0
NMU WILD-TYPE	20	18	9	9

'NMU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S750. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NMU MUTATED	1	1	1	1	0
NMU WILD-TYPE	12	7	13	12	7

'NMU MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0691 (Fisher's exact test), Q value = 1

Table S751. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NMU MUTATED	0	2	0	1
NMU WILD-TYPE	16	6	14	15

'NMU MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.613 (Fisher's exact test), Q value = 1

Table S752. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NMU MUTATED	0	2	0	1
NMU WILD-TYPE	16	14	4	17

'NMU MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S753. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NMU MUTATED	2	1	1
NMU WILD-TYPE	24	10	17

'NMU MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S754. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NMU MUTATED	2	2	0	0	0
NMU WILD-TYPE	11	16	8	14	2

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S755. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NMU MUTATED	1	1	2
NMU WILD-TYPE	20	13	17

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S756. Gene #83: 'NMU MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NMU MUTATED	2	2	0
NMU WILD-TYPE	28	14	8

'TMEM189 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 1

Table S757. Gene #84: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
TMEM189 MUTATED	3	0	0	0
TMEM189 WILD-TYPE	18	20	10	9

'ADAD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.419 (Fisher's exact test), Q value = 1

Table S758. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ADAD2 MUTATED	2	0	1	1
ADAD2 WILD-TYPE	19	20	9	8

'ADAD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S759. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ADAD2 MUTATED	0	0	2	1	1
ADAD2 WILD-TYPE	13	8	12	12	6

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S760. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ADAD2 MUTATED	1	0	2	1
ADAD2 WILD-TYPE	15	8	12	15

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S761. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ADAD2 MUTATED	0	2	1	1
ADAD2 WILD-TYPE	16	14	3	17

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00966 (Fisher's exact test), Q value = 1

Table S762. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ADAD2 MUTATED	0	3	1
ADAD2 WILD-TYPE	26	8	17

Figure S35. Get High-res Image Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S763. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ADAD2 MUTATED	0	3	0	1	0
ADAD2 WILD-TYPE	13	15	8	13	2

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0568 (Fisher's exact test), Q value = 1

Table S764. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ADAD2 MUTATED	0	3	1
ADAD2 WILD-TYPE	21	11	18

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S765. Gene #85: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ADAD2 MUTATED	1	2	1
ADAD2 WILD-TYPE	29	14	7

'PLEC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S766. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PLEC MUTATED	4	7	1	1
PLEC WILD-TYPE	17	13	9	8

'PLEC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S767. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PLEC MUTATED	2	2	1	3	2
PLEC WILD-TYPE	11	6	13	10	5

'PLEC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 1

Table S768. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
PLEC MUTATED	2	3	0	0
PLEC WILD-TYPE	6	5	6	6

'PLEC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0486 (Fisher's exact test), Q value = 1

Table S769. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PLEC MUTATED	0	4	0	0	0	0	1	0
PLEC WILD-TYPE	5	2	5	3	3	1	2	2

Figure S36. Get High-res Image Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

'PLEC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S770. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PLEC MUTATED	2	0	5	3
PLEC WILD-TYPE	14	8	9	13

'PLEC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S771. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PLEC MUTATED	2	4	0	4
PLEC WILD-TYPE	14	12	4	14

'PLEC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.596 (Fisher's exact test), Q value = 1

Table S772. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PLEC MUTATED	6	2	2
PLEC WILD-TYPE	20	9	16

'PLEC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S773. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PLEC MUTATED	4	2	2	2	0
PLEC WILD-TYPE	9	16	6	12	2

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S774. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PLEC MUTATED	6	3	1
PLEC WILD-TYPE	15	11	18

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S775. Gene #86: 'PLEC MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PLEC MUTATED	7	2	1
PLEC WILD-TYPE	23	14	7

'RGMB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S776. Gene #87: 'RGMB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RGMB MUTATED	2	2	2	0
RGMB WILD-TYPE	19	18	8	9

'CLIC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S777. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CLIC6 MUTATED	2	3	0	0
CLIC6 WILD-TYPE	19	17	10	9

'CLIC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S778. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CLIC6 MUTATED	1	1	1	1	0
CLIC6 WILD-TYPE	12	7	13	12	7

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S779. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CLIC6 MUTATED	2	1	0	1
CLIC6 WILD-TYPE	14	7	14	15

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S780. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CLIC6 MUTATED	2	1	1	0
CLIC6 WILD-TYPE	14	15	3	18

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S781. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CLIC6 MUTATED	2	2	0
CLIC6 WILD-TYPE	24	9	18

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S782. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CLIC6 MUTATED	0	1	1	2	0
CLIC6 WILD-TYPE	13	17	7	12	2

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 1

Table S783. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CLIC6 MUTATED	2	2	0
CLIC6 WILD-TYPE	19	12	19

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S784. Gene #88: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CLIC6 MUTATED	3	1	0
CLIC6 WILD-TYPE	27	15	8

'ZNF814 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S785. Gene #89: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ZNF814 MUTATED	1	1	1	0
ZNF814 WILD-TYPE	20	19	9	9

'DSPP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S786. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
DSPP MUTATED	4	4	1	0
DSPP WILD-TYPE	17	16	9	9

'DSPP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0597 (Fisher's exact test), Q value = 1

Table S787. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
DSPP MUTATED	1	4	1	3	0
DSPP WILD-TYPE	12	4	13	10	7

'DSPP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S788. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
DSPP MUTATED	1	2	0	1
DSPP WILD-TYPE	7	6	6	5

'DSPP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S789. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
DSPP MUTATED	1	1	0	1	0	0	0	1
DSPP WILD-TYPE	4	5	5	2	3	1	3	1

'DSPP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S790. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
DSPP MUTATED	3	1	2	3
DSPP WILD-TYPE	13	7	12	13

'DSPP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S791. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
DSPP MUTATED	4	1	1	3
DSPP WILD-TYPE	12	15	3	15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S792. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
DSPP MUTATED	3	3	3
DSPP WILD-TYPE	23	8	15

'DSPP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S793. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
DSPP MUTATED	1	4	1	2	1
DSPP WILD-TYPE	12	14	7	12	1

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.901 (Fisher's exact test), Q value = 1

Table S794. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
DSPP MUTATED	3	3	3
DSPP WILD-TYPE	18	11	16

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S795. Gene #90: 'DSPP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
DSPP MUTATED	5	3	1
DSPP WILD-TYPE	25	13	7

'AMDHD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S796. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AMDHD1 MUTATED	5	2	1	2
AMDHD1 WILD-TYPE	16	18	9	7

'AMDHD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S797. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
AMDHD1 MUTATED	1	1	4	2	1
AMDHD1 WILD-TYPE	12	7	10	11	6

'AMDHD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S798. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
AMDHD1 MUTATED	1	1	0	1
AMDHD1 WILD-TYPE	7	7	6	5

'AMDHD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S799. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
AMDHD1 MUTATED	1	0	0	0	1	0	0	1
AMDHD1 WILD-TYPE	4	6	5	3	2	1	3	1

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S800. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
AMDHD1 MUTATED	3	2	3	1
AMDHD1 WILD-TYPE	13	6	11	15

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.138 (Fisher's exact test), Q value = 1

Table S801. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
AMDHD1 MUTATED	1	4	2	2
AMDHD1 WILD-TYPE	15	12	2	16

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S802. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
AMDHD1 MUTATED	3	4	2
AMDHD1 WILD-TYPE	23	7	16

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S803. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
AMDHD1 MUTATED	1	4	1	3	0
AMDHD1 WILD-TYPE	12	14	7	11	2

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.901 (Fisher's exact test), Q value = 1

Table S804. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
AMDHD1 MUTATED	3	2	4
AMDHD1 WILD-TYPE	18	12	15

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S805. Gene #91: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
AMDHD1 MUTATED	4	3	2
AMDHD1 WILD-TYPE	26	13	6

'CRIPAK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.385 (Fisher's exact test), Q value = 1

Table S806. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CRIPAK MUTATED	2	4	1	3
CRIPAK WILD-TYPE	19	16	9	6

'CRIPAK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S807. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CRIPAK MUTATED	2	1	2	2	2
CRIPAK WILD-TYPE	11	7	12	11	5

'CRIPAK MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S808. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
CRIPAK MUTATED	1	2	1	0
CRIPAK WILD-TYPE	7	6	5	6

'CRIPAK MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S809. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
CRIPAK MUTATED	1	2	1	0	0	0	0	0
CRIPAK WILD-TYPE	4	4	4	3	3	1	3	2

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S810. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CRIPAK MUTATED	2	0	3	4
CRIPAK WILD-TYPE	14	8	11	12

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S811. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CRIPAK MUTATED	2	2	1	4
CRIPAK WILD-TYPE	14	14	3	14

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S812. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CRIPAK MUTATED	5	1	3
CRIPAK WILD-TYPE	21	10	15

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S813. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CRIPAK MUTATED	1	4	3	1	0
CRIPAK WILD-TYPE	12	14	5	13	2

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S814. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CRIPAK MUTATED	5	1	3
CRIPAK WILD-TYPE	16	13	16

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 1

Table S815. Gene #92: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CRIPAK MUTATED	5	4	0
CRIPAK WILD-TYPE	25	12	8

'NOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S816. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NOM1 MUTATED	2	2	1	1
NOM1 WILD-TYPE	19	18	9	8

'NOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S817. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NOM1 MUTATED	1	1	1	0	2
NOM1 WILD-TYPE	12	7	13	13	5

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S818. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NOM1 MUTATED	2	0	1	2
NOM1 WILD-TYPE	14	8	13	14

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S819. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NOM1 MUTATED	2	1	0	2
NOM1 WILD-TYPE	14	15	4	16

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S820. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NOM1 MUTATED	2	1	2
NOM1 WILD-TYPE	24	10	16

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S821. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NOM1 MUTATED	2	1	1	1	0
NOM1 WILD-TYPE	11	17	7	13	2

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S822. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NOM1 MUTATED	3	0	2
NOM1 WILD-TYPE	18	14	17

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S823. Gene #93: 'NOM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NOM1 MUTATED	3	1	1
NOM1 WILD-TYPE	27	15	7

'MAP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S824. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MAP7 MUTATED	2	1	0	0
MAP7 WILD-TYPE	19	19	10	9

'MAP7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 1

Table S825. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
MAP7 MUTATED	1	0	0	1	1
MAP7 WILD-TYPE	12	8	14	12	6

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S826. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
MAP7 MUTATED	1	0	1	1
MAP7 WILD-TYPE	15	8	13	15

'MAP7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S827. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
MAP7 MUTATED	1	0	0	2
MAP7 WILD-TYPE	15	16	4	16

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S828. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
MAP7 MUTATED	1	0	2
MAP7 WILD-TYPE	25	11	16

'MAP7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S829. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
MAP7 MUTATED	0	1	1	1	0
MAP7 WILD-TYPE	13	17	7	13	2

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S830. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
MAP7 MUTATED	1	1	1
MAP7 WILD-TYPE	20	13	18

'MAP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S831. Gene #94: 'MAP7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
MAP7 MUTATED	1	1	1
MAP7 WILD-TYPE	29	15	7

'PTX4 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S832. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PTX4 MUTATED	1	1	1	0
PTX4 WILD-TYPE	20	19	9	9

'PTX4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S833. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PTX4 MUTATED	1	0	1	1	0
PTX4 WILD-TYPE	12	8	13	12	7

'PTX4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S834. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PTX4 MUTATED	2	0	1	0
PTX4 WILD-TYPE	14	8	13	16

'PTX4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.195 (Fisher's exact test), Q value = 1

Table S835. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PTX4 MUTATED	1	1	1	0
PTX4 WILD-TYPE	15	15	3	18

'PTX4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S836. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PTX4 MUTATED	2	1	0
PTX4 WILD-TYPE	24	10	18

'PTX4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S837. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PTX4 MUTATED	1	1	0	1	0
PTX4 WILD-TYPE	12	17	8	13	2

'PTX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 1

Table S838. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PTX4 MUTATED	1	2	0
PTX4 WILD-TYPE	20	12	19

'PTX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.255 (Fisher's exact test), Q value = 1

Table S839. Gene #95: 'PTX4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PTX4 MUTATED	2	0	1
PTX4 WILD-TYPE	28	16	7

'LRP11 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S840. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
LRP11 MUTATED	2	2	1	0
LRP11 WILD-TYPE	19	18	9	9

'LRP11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0797 (Fisher's exact test), Q value = 1

Table S841. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
LRP11 MUTATED	1	0	4	0	0
LRP11 WILD-TYPE	12	8	10	13	7

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S842. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
LRP11 MUTATED	1	1	2	1
LRP11 WILD-TYPE	15	7	12	15

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.664 (Fisher's exact test), Q value = 1

Table S843. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
LRP11 MUTATED	1	3	0	1
LRP11 WILD-TYPE	15	13	4	17

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S844. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
LRP11 MUTATED	2	2	1
LRP11 WILD-TYPE	24	9	17

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S845. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
LRP11 MUTATED	1	2	0	2	0
LRP11 WILD-TYPE	12	16	8	12	2

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S846. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
LRP11 MUTATED	2	2	1
LRP11 WILD-TYPE	19	12	18

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S847. Gene #96: 'LRP11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
LRP11 MUTATED	3	2	0
LRP11 WILD-TYPE	27	14	8

'PDCD6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S848. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PDCD6 MUTATED	0	1	1	1
PDCD6 WILD-TYPE	21	19	9	8

'PDCD6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S849. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PDCD6 MUTATED	1	0	0	1	1
PDCD6 WILD-TYPE	12	8	14	12	6

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S850. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PDCD6 MUTATED	2	0	1
PDCD6 WILD-TYPE	24	11	17

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S851. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PDCD6 MUTATED	1	1	1	0	0
PDCD6 WILD-TYPE	12	17	7	14	2

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S852. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PDCD6 MUTATED	1	1	1
PDCD6 WILD-TYPE	20	13	18

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S853. Gene #97: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PDCD6 MUTATED	2	1	0
PDCD6 WILD-TYPE	28	15	8

'SHOX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S854. Gene #98: 'SHOX2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SHOX2 MUTATED	2	0	0	1
SHOX2 WILD-TYPE	19	20	10	8

'UQCRFS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S855. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
UQCRFS1 MUTATED	1	1	1	1
UQCRFS1 WILD-TYPE	20	19	9	8

'UQCRFS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S856. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
UQCRFS1 MUTATED	2	1	2	0	0
UQCRFS1 WILD-TYPE	11	7	12	13	7

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S857. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
UQCRFS1 MUTATED	1	1	1	1
UQCRFS1 WILD-TYPE	15	7	13	15

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S858. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
UQCRFS1 MUTATED	1	2	0	1
UQCRFS1 WILD-TYPE	15	14	4	17

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S859. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
UQCRFS1 MUTATED	4	0	1
UQCRFS1 WILD-TYPE	22	11	17

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.202 (Fisher's exact test), Q value = 1

Table S860. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
UQCRFS1 MUTATED	3	0	1	1	0
UQCRFS1 WILD-TYPE	10	18	7	13	2

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S861. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
UQCRFS1 MUTATED	2	2	1
UQCRFS1 WILD-TYPE	19	12	18

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S862. Gene #99: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
UQCRFS1 MUTATED	4	0	1
UQCRFS1 WILD-TYPE	26	16	7

'CTBP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S863. Gene #100: 'CTBP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CTBP2 MUTATED	1	2	0	0
CTBP2 WILD-TYPE	20	18	10	9

'PRKAR1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S864. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PRKAR1A MUTATED	2	1	2	1
PRKAR1A WILD-TYPE	19	19	8	8

'PRKAR1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S865. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PRKAR1A MUTATED	1	1	2	1	1
PRKAR1A WILD-TYPE	12	7	12	12	6

'PRKAR1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S866. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
PRKAR1A MUTATED	1	2	0	1
PRKAR1A WILD-TYPE	7	6	6	5

'PRKAR1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S867. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
PRKAR1A MUTATED	1	2	0	0	1	0	0	0
PRKAR1A WILD-TYPE	4	4	5	3	2	1	3	2

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S868. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PRKAR1A MUTATED	2	1	3	0
PRKAR1A WILD-TYPE	14	7	11	16

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S869. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PRKAR1A MUTATED	1	3	1	1
PRKAR1A WILD-TYPE	15	13	3	17

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 1

Table S870. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PRKAR1A MUTATED	5	1	0
PRKAR1A WILD-TYPE	21	10	18

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S871. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PRKAR1A MUTATED	3	1	1	1	0
PRKAR1A WILD-TYPE	10	17	7	13	2

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0493 (Fisher's exact test), Q value = 1

Table S872. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PRKAR1A MUTATED	5	1	0
PRKAR1A WILD-TYPE	16	13	19

Figure S37. Get High-res Image Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S873. Gene #101: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PRKAR1A MUTATED	5	1	0
PRKAR1A WILD-TYPE	25	15	8

'JMJD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S874. Gene #102: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
JMJD4 MUTATED	1	1	1	0
JMJD4 WILD-TYPE	20	19	9	9

'HSD17B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S875. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
HSD17B1 MUTATED	2	2	0	0
HSD17B1 WILD-TYPE	19	18	10	9

'HSD17B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0479 (Fisher's exact test), Q value = 1

Table S876. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
HSD17B1 MUTATED	0	0	0	3	1
HSD17B1 WILD-TYPE	13	8	14	10	6

Figure S38. Get High-res Image Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'HSD17B1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S877. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
HSD17B1 MUTATED	1	0	1	1
HSD17B1 WILD-TYPE	7	8	5	5

'HSD17B1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S878. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
HSD17B1 MUTATED	0	0	1	0	1	0	1	0
HSD17B1 WILD-TYPE	5	6	4	3	2	1	2	2

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.91 (Fisher's exact test), Q value = 1

Table S879. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
HSD17B1 MUTATED	2	0	1	1
HSD17B1 WILD-TYPE	14	8	13	15

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0082 (Fisher's exact test), Q value = 1

Table S880. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
HSD17B1 MUTATED	0	0	2	2
HSD17B1 WILD-TYPE	16	16	2	16

Figure S39. Get High-res Image Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S881. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
HSD17B1 MUTATED	2	1	1
HSD17B1 WILD-TYPE	24	10	17

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S882. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
HSD17B1 MUTATED	1	1	0	2	0
HSD17B1 WILD-TYPE	12	17	8	12	2

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S883. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
HSD17B1 MUTATED	2	0	2
HSD17B1 WILD-TYPE	19	14	17

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S884. Gene #103: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
HSD17B1 MUTATED	2	1	1
HSD17B1 WILD-TYPE	28	15	7

'COQ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S885. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
COQ2 MUTATED	1	1	1	2
COQ2 WILD-TYPE	20	19	9	7

'COQ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S886. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
COQ2 MUTATED	0	1	1	1	1
COQ2 WILD-TYPE	13	7	13	12	6

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S887. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
COQ2 MUTATED	0	1	2	1
COQ2 WILD-TYPE	16	7	12	15

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S888. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
COQ2 MUTATED	0	2	0	2
COQ2 WILD-TYPE	16	14	4	16

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S889. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
COQ2 MUTATED	2	1	1
COQ2 WILD-TYPE	24	10	17

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S890. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
COQ2 MUTATED	1	2	1	0	0
COQ2 WILD-TYPE	12	16	7	14	2

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S891. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
COQ2 MUTATED	2	0	2
COQ2 WILD-TYPE	19	14	17

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S892. Gene #104: 'COQ2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
COQ2 MUTATED	2	2	0
COQ2 WILD-TYPE	28	14	8

'FEZ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S893. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
FEZ2 MUTATED	0	2	1	0
FEZ2 WILD-TYPE	21	18	9	9

'FEZ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.354 (Fisher's exact test), Q value = 1

Table S894. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
FEZ2 MUTATED	0	1	1	0	1
FEZ2 WILD-TYPE	13	7	13	13	6

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 1

Table S895. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
FEZ2 MUTATED	0	1	0	2
FEZ2 WILD-TYPE	16	7	14	14

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S896. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
FEZ2 MUTATED	1	0	0	2
FEZ2 WILD-TYPE	15	16	4	16

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S897. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
FEZ2 MUTATED	0	1	2
FEZ2 WILD-TYPE	26	10	16

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S898. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
FEZ2 MUTATED	0	1	1	1	0
FEZ2 WILD-TYPE	13	17	7	13	2

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S899. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
FEZ2 MUTATED	2	0	1
FEZ2 WILD-TYPE	19	14	18

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.556 (Fisher's exact test), Q value = 1

Table S900. Gene #105: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
FEZ2 MUTATED	1	1	1
FEZ2 WILD-TYPE	29	15	7

'DLEU7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S901. Gene #106: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
DLEU7 MUTATED	2	0	1	0
DLEU7 WILD-TYPE	19	20	9	9

'RNF135 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S902. Gene #107: 'RNF135 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
RNF135 MUTATED	1	2	0	0
RNF135 WILD-TYPE	20	18	10	9

'SPIRE2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S903. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SPIRE2 MUTATED	0	1	1	1
SPIRE2 WILD-TYPE	21	19	9	8

'SPIRE2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0386 (Fisher's exact test), Q value = 1

Table S904. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
SPIRE2 MUTATED	1	0	0	0	2
SPIRE2 WILD-TYPE	12	8	14	13	5

Figure S40. Get High-res Image Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S905. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
SPIRE2 MUTATED	1	0	1	1
SPIRE2 WILD-TYPE	15	8	13	15

'SPIRE2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S906. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
SPIRE2 MUTATED	1	0	0	2
SPIRE2 WILD-TYPE	15	16	4	16

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S907. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
SPIRE2 MUTATED	2	0	1
SPIRE2 WILD-TYPE	24	11	17

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S908. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
SPIRE2 MUTATED	0	1	1	1	0
SPIRE2 WILD-TYPE	13	17	7	13	2

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S909. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
SPIRE2 MUTATED	1	1	1
SPIRE2 WILD-TYPE	20	13	18

'SPIRE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S910. Gene #108: 'SPIRE2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
SPIRE2 MUTATED	2	1	0
SPIRE2 WILD-TYPE	28	15	8

'KRTAP5-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S911. Gene #109: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KRTAP5-5 MUTATED	1	1	1	0
KRTAP5-5 WILD-TYPE	20	19	9	9

'SGK223 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S912. Gene #110: 'SGK223 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
SGK223 MUTATED	1	2	0	0
SGK223 WILD-TYPE	20	18	10	9

'C9ORF66 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S913. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
C9ORF66 MUTATED	2	2	1	0
C9ORF66 WILD-TYPE	19	18	9	9

'C9ORF66 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S914. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
C9ORF66 MUTATED	1	1	1	2	0
C9ORF66 WILD-TYPE	12	7	13	11	7

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S915. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
C9ORF66 MUTATED	2	1	1	1
C9ORF66 WILD-TYPE	14	7	13	15

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S916. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
C9ORF66 MUTATED	1	2	1	1
C9ORF66 WILD-TYPE	15	14	3	17

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S917. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
C9ORF66 MUTATED	2	2	1
C9ORF66 WILD-TYPE	24	9	17

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S918. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
C9ORF66 MUTATED	1	2	0	2	0
C9ORF66 WILD-TYPE	12	16	8	12	2

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S919. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
C9ORF66 MUTATED	2	0	3
C9ORF66 WILD-TYPE	19	14	16

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S920. Gene #111: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
C9ORF66 MUTATED	2	2	1
C9ORF66 WILD-TYPE	28	14	7

'AQP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S921. Gene #112: 'AQP7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
AQP7 MUTATED	1	2	0	0
AQP7 WILD-TYPE	20	18	10	9

'ADAMTS7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 1

Table S922. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
ADAMTS7 MUTATED	0	3	0	1
ADAMTS7 WILD-TYPE	21	17	10	8

'ADAMTS7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S923. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
ADAMTS7 MUTATED	0	0	1	2	1
ADAMTS7 WILD-TYPE	13	8	13	11	6

'ADAMTS7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0124 (Fisher's exact test), Q value = 1

Table S924. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	8	8	6	6
ADAMTS7 MUTATED	0	0	0	3
ADAMTS7 WILD-TYPE	8	8	6	3

Figure S41. Get High-res Image Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

'ADAMTS7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S925. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8
ALL	5	6	5	3	3	1	3	2
ADAMTS7 MUTATED	0	0	2	0	1	0	0	0
ADAMTS7 WILD-TYPE	5	6	3	3	2	1	3	2

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0905 (Fisher's exact test), Q value = 1

Table S926. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
ADAMTS7 MUTATED	0	1	0	3
ADAMTS7 WILD-TYPE	16	7	14	13

'ADAMTS7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S927. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
ADAMTS7 MUTATED	0	1	0	3
ADAMTS7 WILD-TYPE	16	15	4	15

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0824 (Fisher's exact test), Q value = 1

Table S928. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
ADAMTS7 MUTATED	0	1	3
ADAMTS7 WILD-TYPE	26	10	15

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S929. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
ADAMTS7 MUTATED	0	3	1	0	0
ADAMTS7 WILD-TYPE	13	15	7	14	2

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S930. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
ADAMTS7 MUTATED	0	1	3
ADAMTS7 WILD-TYPE	21	13	16

'ADAMTS7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0387 (Fisher's exact test), Q value = 1

Table S931. Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
ADAMTS7 MUTATED	0	3	1
ADAMTS7 WILD-TYPE	30	13	7

Figure S42. Get High-res Image Gene #113: 'ADAMTS7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PCDHB13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.395 (Fisher's exact test), Q value = 1

Table S932. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
PCDHB13 MUTATED	1	1	2	1
PCDHB13 WILD-TYPE	20	19	8	8

'PCDHB13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S933. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
PCDHB13 MUTATED	0	1	3	0	0
PCDHB13 WILD-TYPE	13	7	11	13	7

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.127 (Fisher's exact test), Q value = 1

Table S934. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
PCDHB13 MUTATED	0	0	3	1
PCDHB13 WILD-TYPE	16	8	11	15

'PCDHB13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 1

Table S935. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
PCDHB13 MUTATED	0	3	0	1
PCDHB13 WILD-TYPE	16	13	4	17

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S936. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
PCDHB13 MUTATED	3	0	1
PCDHB13 WILD-TYPE	23	11	17

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0596 (Fisher's exact test), Q value = 1

Table S937. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
PCDHB13 MUTATED	3	0	1	0	0
PCDHB13 WILD-TYPE	10	18	7	14	2

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S938. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
PCDHB13 MUTATED	3	0	1
PCDHB13 WILD-TYPE	18	14	18

'PCDHB13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S939. Gene #114: 'PCDHB13 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
PCDHB13 MUTATED	3	0	1
PCDHB13 WILD-TYPE	27	16	7

'CSGALNACT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 1

Table S940. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
CSGALNACT2 MUTATED	0	3	0	0
CSGALNACT2 WILD-TYPE	21	17	10	9

'CSGALNACT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0388 (Fisher's exact test), Q value = 1

Table S941. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
CSGALNACT2 MUTATED	1	0	0	0	2
CSGALNACT2 WILD-TYPE	12	8	14	13	5

Figure S43. Get High-res Image Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S942. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
CSGALNACT2 MUTATED	1	0	0	2
CSGALNACT2 WILD-TYPE	15	8	14	14

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S943. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
CSGALNACT2 MUTATED	1	0	0	2
CSGALNACT2 WILD-TYPE	15	16	4	16

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.583 (Fisher's exact test), Q value = 1

Table S944. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
CSGALNACT2 MUTATED	1	0	2
CSGALNACT2 WILD-TYPE	25	11	16

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S945. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
CSGALNACT2 MUTATED	0	2	0	1	0
CSGALNACT2 WILD-TYPE	13	16	8	13	2

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S946. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
CSGALNACT2 MUTATED	0	1	2
CSGALNACT2 WILD-TYPE	21	13	17

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S947. Gene #115: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
CSGALNACT2 MUTATED	1	2	0
CSGALNACT2 WILD-TYPE	29	14	8

'HLA-A MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S948. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
HLA-A MUTATED	2	1	0	0
HLA-A WILD-TYPE	19	19	10	9

'HLA-A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S949. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
HLA-A MUTATED	1	0	1	1	0
HLA-A WILD-TYPE	12	8	13	12	7

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S950. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
HLA-A MUTATED	1	1	0	1
HLA-A WILD-TYPE	15	7	14	15

'HLA-A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 1

Table S951. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
HLA-A MUTATED	1	1	1	0
HLA-A WILD-TYPE	15	15	3	18

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S952. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
HLA-A MUTATED	2	0	1
HLA-A WILD-TYPE	24	11	17

'HLA-A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S953. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
HLA-A MUTATED	1	0	1	1	0
HLA-A WILD-TYPE	12	18	7	13	2

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S954. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
HLA-A MUTATED	2	0	1
HLA-A WILD-TYPE	19	14	18

'HLA-A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S955. Gene #116: 'HLA-A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
HLA-A MUTATED	2	0	1
HLA-A WILD-TYPE	28	16	7

'MTFMT MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S956. Gene #117: 'MTFMT MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
MTFMT MUTATED	2	1	0	0
MTFMT WILD-TYPE	19	19	10	9

'NLRP5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S957. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
NLRP5 MUTATED	2	2	0	0
NLRP5 WILD-TYPE	19	18	10	9

'NLRP5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.171 (Fisher's exact test), Q value = 1

Table S958. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
NLRP5 MUTATED	0	0	0	2	1
NLRP5 WILD-TYPE	13	8	14	11	6

'NLRP5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S959. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
NLRP5 MUTATED	1	0	1	1
NLRP5 WILD-TYPE	15	8	13	15

'NLRP5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 1

Table S960. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
NLRP5 MUTATED	0	0	1	2
NLRP5 WILD-TYPE	16	16	3	16

'NLRP5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S961. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
NLRP5 MUTATED	1	1	1
NLRP5 WILD-TYPE	25	10	17

'NLRP5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S962. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
NLRP5 MUTATED	1	1	1	0	0
NLRP5 WILD-TYPE	12	17	7	14	2

'NLRP5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S963. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
NLRP5 MUTATED	1	1	1
NLRP5 WILD-TYPE	20	13	18

'NLRP5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.076 (Fisher's exact test), Q value = 1

Table S964. Gene #118: 'NLRP5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
NLRP5 MUTATED	1	0	2
NLRP5 WILD-TYPE	29	16	6

'KCNJ11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0191 (Fisher's exact test), Q value = 1

Table S965. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	21	20	10	9
KCNJ11 MUTATED	0	1	3	0
KCNJ11 WILD-TYPE	21	19	7	9

Figure S44. Get High-res Image Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KCNJ11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S966. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	8	14	13	7
KCNJ11 MUTATED	1	1	2	0	0
KCNJ11 WILD-TYPE	12	7	12	13	7

'KCNJ11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S967. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	8	14	16
KCNJ11 MUTATED	1	1	2	0
KCNJ11 WILD-TYPE	15	7	12	16

'KCNJ11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.23 (Fisher's exact test), Q value = 1

Table S968. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	16	16	4	18
KCNJ11 MUTATED	1	3	0	0
KCNJ11 WILD-TYPE	15	13	4	18

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 1

Table S969. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	11	18
KCNJ11 MUTATED	4	0	0
KCNJ11 WILD-TYPE	22	11	18

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0534 (Fisher's exact test), Q value = 1

Table S970. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	13	18	8	14	2
KCNJ11 MUTATED	2	0	0	1	1
KCNJ11 WILD-TYPE	11	18	8	13	1

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S971. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	21	14	19
KCNJ11 MUTATED	2	2	0
KCNJ11 WILD-TYPE	19	12	19

'KCNJ11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 1

Table S972. Gene #119: 'KCNJ11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	30	16	8
KCNJ11 MUTATED	4	0	0
KCNJ11 WILD-TYPE	26	16	8

Methods & Data

Input

Mutation data file = transformed.cor.cli.txt
Molecular subtypes file = ACC-TP.transferedmergedcluster.txt
Number of patients = 62
Number of significantly mutated genes = 119
Number of Molecular subtypes = 10
Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References

[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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