Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.042 0.146 0.423 45.0 -9999.0 0.0 45.0 KIRREL -0.052 0.187 -9999.0 0.0 -0.586 39.0 39.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.042 0.146 -9999.0 0.0 -0.423 45.0 45.0 PLCG1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.05 0.116 -9999.0 0.0 -0.333 39.0 39.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.007 0.103 -9999.0 0.0 -0.396 6.0 6.0 FYN -0.03 0.122 -9999.0 0.0 -0.327 40.0 40.0 mol:Ca2+ -0.049 0.115 -9999.0 0.0 -0.33 39.0 39.0 mol:DAG -0.05 0.116 -9999.0 0.0 -0.332 39.0 39.0 NPHS2 -0.025 0.114 -9999.0 0.0 -0.513 18.0 18.0 mol:IP3 -0.05 0.116 -9999.0 0.0 -0.332 39.0 39.0 regulation of endocytosis -0.019 0.115 -9999.0 0.0 -0.338 21.0 21.0 Nephrin/NEPH1/podocin/Cholesterol -0.041 0.124 -9999.0 0.0 -0.31 59.0 59.0 establishment of cell polarity -0.042 0.146 -9999.0 0.0 -0.423 45.0 45.0 Nephrin/NEPH1/podocin/NCK1-2 -0.014 0.116 -9999.0 0.0 -0.457 6.0 6.0 Nephrin/NEPH1/beta Arrestin2 -0.018 0.117 -9999.0 0.0 -0.342 21.0 21.0 NPHS1 -0.009 0.068 -9999.0 0.0 -0.498 6.0 6.0 Nephrin/NEPH1/podocin -0.03 0.122 -9999.0 0.0 -0.329 40.0 40.0 TJP1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.05 0.116 -9999.0 0.0 -0.333 39.0 39.0 CD2AP 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.05 0.116 -9999.0 0.0 -0.333 39.0 39.0 GRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.026 0.122 -9999.0 0.0 -0.32 40.0 40.0 cytoskeleton organization -0.007 0.12 -9999.0 0.0 -0.469 6.0 6.0 Nephrin/NEPH1 -0.027 0.105 -9999.0 0.0 -0.3 45.0 45.0 Nephrin/NEPH1/ZO-1 -0.042 0.11 -9999.0 0.0 -0.34 39.0 39.0