Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 89 (22%) 319 4e-05 0.0302 0.02705 1 0.29194 1 0.2234 1 0.44405 1 0.73401 1 0.78797 1 0.249 1 0.794 1 0.04847 1 1q gain 128 (31%) 280 0.00155 1 0.3295 1 0.67452 1 0.97288 1 0.45163 1 0.82855 1 0.33226 1 0.5315 1 0.30554 1 0.46987 1 2p gain 110 (27%) 298 9.9999e-06 0.008 0.00029 0.214 0.32607 1 0.73473 1 0.19575 1 0.03367 1 0.096799 1 0.01406 1 0.23176 1 0.00196 1 2q gain 55 (13%) 353 9.9999e-06 0.008 0.13479 1 0.61606 1 0.29663 1 0.732 1 0.71007 1 0.10136 1 0.35998 1 0.68176 1 0.42622 1 3p gain 140 (34%) 268 0.00048 0.349 0.78133 1 0.15759 1 0.23354 1 0.0087499 1 0.01375 1 0.01317 1 0.04121 1 0.0097499 1 3e-04 0.221 3q gain 178 (44%) 230 4e-05 0.0302 0.95089 1 0.45256 1 0.99413 1 0.21486 1 0.063599 1 0.0089799 1 0.0094199 1 0.0064099 1 9.9999e-06 0.008 4p gain 39 (10%) 369 0.060159 1 0.00389 1 0.60643 1 0.41553 1 0.01834 1 0.0071599 1 0.0099999 1 0.54725 1 0.32349 1 0.5703 1 4q gain 25 (6%) 383 0.03863 1 0.2146 1 0.54576 1 0.20365 1 0.079899 1 0.32079 1 0.03282 1 0.46633 1 0.31903 1 0.27014 1 5p gain 166 (41%) 242 9.9999e-06 0.008 0.39009 1 0.04268 1 0.24015 1 0.16684 1 0.00143 1 0.83679 1 0.00253 1 0.091539 1 0.00459 1 5q gain 51 (12%) 357 0.01727 1 0.69448 1 0.0099699 1 0.13571 1 0.38317 1 0.36246 1 0.48553 1 0.18741 1 0.62105 1 0.068579 1 6p gain 75 (18%) 333 0.00365 1 0.41301 1 0.84783 1 0.13283 1 0.5754 1 0.17236 1 0.94423 1 0.66505 1 0.22185 1 0.29712 1 6q gain 41 (10%) 367 0.04419 1 0.32867 1 0.97529 1 0.04053 1 0.59909 1 0.18108 1 0.50321 1 0.44516 1 0.04121 1 0.02543 1 7p gain 172 (42%) 236 9.9999e-06 0.008 0.01295 1 0.0135 1 0.33848 1 0.62972 1 0.12128 1 0.2954 1 0.03456 1 0.2462 1 0.00025 0.185 7q gain 150 (37%) 258 9.9999e-06 0.008 0.0068199 1 0.16251 1 0.83029 1 0.50117 1 0.13539 1 0.10758 1 0.1177 1 0.84846 1 0.00456 1 8p gain 92 (23%) 316 0.00063999 0.463 0.27337 1 0.14989 1 0.03701 1 0.28628 1 0.80595 1 0.2203 1 0.01962 1 0.70097 1 0.10715 1 8q gain 204 (50%) 204 0.00086999 0.626 0.12522 1 0.055609 1 0.13794 1 0.80743 1 0.97996 1 0.35679 1 0.03282 1 0.73716 1 0.058219 1 9p gain 68 (17%) 340 9.9999e-06 0.008 0.12958 1 0.85832 1 0.58462 1 0.44652 1 0.40994 1 0.37898 1 0.24457 1 5.9999e-05 0.0449 9.9999e-06 0.008 9q gain 56 (14%) 352 5e-05 0.0375 0.02772 1 0.88002 1 0.02954 1 0.03891 1 0.00259 1 0.84885 1 0.31057 1 0.00049 0.356 3e-05 0.0227 10p gain 117 (29%) 291 9.9999e-06 0.008 0.78665 1 0.81708 1 0.46797 1 0.60512 1 0.02528 1 0.92965 1 0.75335 1 0.76532 1 0.0093099 1 10q gain 44 (11%) 364 0.00022 0.163 0.19452 1 0.36171 1 0.37058 1 0.47387 1 0.02549 1 0.41948 1 0.99385 1 0.13719 1 0.073489 1 11p gain 29 (7%) 379 0.00412 1 0.11505 1 0.19536 1 0.15331 1 0.21418 1 0.053689 1 0.96839 1 0.46906 1 0.00401 1 0.03335 1 11q gain 48 (12%) 360 0.0063799 1 0.53428 1 0.19894 1 0.03156 1 0.64635 1 0.00295 1 0.81449 1 0.7506 1 0.01579 1 0.12129 1 12p gain 115 (28%) 293 3e-05 0.0227 0.04612 1 0.70492 1 0.40403 1 0.85482 1 0.87176 1 0.89922 1 0.02495 1 0.33827 1 0.12682 1 12q gain 90 (22%) 318 0.00228 1 0.55403 1 0.068169 1 0.01289 1 0.15188 1 0.2489 1 0.59298 1 0.056969 1 0.79957 1 0.03756 1 13q gain 100 (25%) 308 0.0096599 1 0.83496 1 0.94192 1 0.74803 1 0.3808 1 0.59267 1 0.72179 1 0.82465 1 0.23235 1 0.01625 1 14q gain 59 (14%) 349 0.00056999 0.413 0.35455 1 0.3795 1 0.15044 1 0.051219 1 0.090599 1 0.74349 1 0.21261 1 0.56874 1 0.4526 1 15q gain 34 (8%) 374 0.28481 1 0.0022 1 0.70904 1 0.57586 1 0.77481 1 0.02152 1 0.1001 1 0.72969 1 0.20883 1 0.14639 1 16p gain 75 (18%) 333 0.04157 1 0.30318 1 0.42999 1 0.27368 1 0.31031 1 0.079619 1 0.44805 1 0.26382 1 0.53942 1 0.45339 1 16q gain 81 (20%) 327 0.11433 1 0.098549 1 0.32746 1 0.19567 1 0.26046 1 0.087939 1 0.22778 1 0.13677 1 0.63872 1 0.20398 1 17p gain 56 (14%) 352 0.00036 0.264 0.16502 1 0.42683 1 0.96025 1 0.48248 1 0.03481 1 0.02614 1 0.19539 1 0.11327 1 0.02703 1 17q gain 136 (33%) 272 0.00078999 0.569 0.074469 1 0.50791 1 0.5405 1 0.10939 1 0.27254 1 0.16955 1 0.17461 1 0.16395 1 0.00133 0.943 18p gain 116 (28%) 292 9.9999e-06 0.008 0.00052999 0.385 0.95132 1 0.91117 1 0.20061 1 0.059209 1 0.39012 1 0.12692 1 0.058499 1 5e-05 0.0375 18q gain 63 (15%) 345 0.00118 0.841 0.01188 1 0.32287 1 0.30199 1 0.59664 1 0.99012 1 0.087159 1 0.54907 1 0.29862 1 0.0059499 1 19p gain 88 (22%) 320 0.00033 0.242 0.62031 1 0.50661 1 0.59708 1 0.13671 1 0.37976 1 0.60933 1 0.47293 1 0.12735 1 0.73804 1 19q gain 135 (33%) 273 9.9999e-06 0.008 0.31299 1 0.44259 1 0.67939 1 0.53019 1 0.43302 1 0.49991 1 0.03975 1 0.15196 1 0.19528 1 20p gain 202 (50%) 206 2e-05 0.0152 0.02403 1 0.56909 1 0.04863 1 0.28666 1 0.02201 1 0.31388 1 0.070679 1 0.02683 1 0.060769 1 20q gain 230 (56%) 178 9.9999e-06 0.008 0.063929 1 0.37214 1 0.1805 1 0.46104 1 0.21114 1 0.20012 1 0.12792 1 0.21868 1 0.01533 1 21q gain 117 (29%) 291 9.9999e-06 0.008 0.0093599 1 0.50007 1 0.26557 1 0.00381 1 0.00433 1 0.00264 1 0.00439 1 0.02043 1 0.17306 1 22q gain 50 (12%) 358 0.00129 0.916 0.00146 1 0.59139 1 0.56658 1 0.00128 0.91 0.066379 1 0.13905 1 0.32861 1 0.052639 1 0.10423 1 xq gain 49 (12%) 359 0.01928 1 0.081389 1 0.74909 1 0.77961 1 0.49092 1 0.34758 1 0.14848 1 0.22487 1 0.25088 1 0.56775 1 1p loss 30 (7%) 378 0.11489 1 0.52064 1 0.25235 1 0.12194 1 0.61974 1 0.38757 1 0.41701 1 0.83416 1 0.78405 1 0.7851 1 1q loss 30 (7%) 378 0.03033 1 0.84595 1 0.39952 1 0.95744 1 0.53429 1 0.60169 1 0.85743 1 0.25746 1 0.52013 1 0.050079 1 2p loss 44 (11%) 364 0.088069 1 0.16132 1 0.96141 1 0.74863 1 0.22035 1 0.089139 1 0.48955 1 0.69784 1 0.1829 1 0.16093 1 2q loss 90 (22%) 318 0.00026 0.192 0.00098999 0.707 0.75175 1 0.54269 1 0.050579 1 0.055349 1 0.73322 1 0.69403 1 0.03563 1 0.01193 1 3p loss 52 (13%) 356 0.30077 1 0.12528 1 0.0217 1 0.02476 1 9.9999e-06 0.008 9.9999e-06 0.008 0.4418 1 0.00091999 0.661 3e-05 0.0227 0.00015 0.112 3q loss 23 (6%) 385 0.59853 1 0.43955 1 0.00328 1 0.01336 1 0.058029 1 0.01393 1 0.88997 1 0.23255 1 0.00093999 0.674 0.14218 1 4p loss 142 (35%) 266 9.9999e-06 0.008 0.0093399 1 0.38611 1 0.44544 1 0.02069 1 0.00162 1 0.078129 1 0.02854 1 0.03077 1 0.10095 1 4q loss 136 (33%) 272 9.9999e-06 0.008 0.00226 1 0.13901 1 0.19174 1 0.16266 1 0.00461 1 0.59233 1 0.052259 1 0.00384 1 0.00314 1 5p loss 54 (13%) 354 0.03578 1 0.44385 1 0.31561 1 0.66525 1 0.51369 1 0.01699 1 0.89594 1 0.70213 1 0.059519 1 0.02654 1 5q loss 159 (39%) 249 9.9999e-06 0.008 0.01074 1 0.79537 1 0.18822 1 0.3339 1 0.059869 1 0.22735 1 0.01902 1 0.28826 1 0.01346 1 6p loss 100 (25%) 308 9.9999e-06 0.008 0.00027 0.199 0.63704 1 0.75813 1 0.12141 1 0.0054399 1 0.24223 1 0.01084 1 0.22372 1 0.00095999 0.687 6q loss 156 (38%) 252 9.9999e-06 0.008 0.00387 1 0.83192 1 0.48802 1 0.39482 1 0.089439 1 0.17899 1 0.00456 1 0.59796 1 5e-05 0.0375 7p loss 19 (5%) 389 0.30548 1 0.62943 1 0.26801 1 0.61986 1 0.80302 1 0.77604 1 0.24351 1 0.098839 1 0.26329 1 0.23889 1 7q loss 27 (7%) 381 0.03343 1 0.83759 1 0.32294 1 0.42793 1 0.6831 1 0.98898 1 0.44014 1 0.23163 1 0.56188 1 0.29613 1 8p loss 185 (45%) 223 9.9999e-06 0.008 0.01891 1 0.14578 1 0.10205 1 0.02579 1 0.15016 1 0.16742 1 0.15056 1 0.2846 1 0.00379 1 8q loss 33 (8%) 375 0.099139 1 0.81547 1 0.31977 1 0.0095999 1 0.087889 1 0.18742 1 0.28709 1 0.64868 1 0.64678 1 0.66946 1 9p loss 174 (43%) 234 9.9999e-06 0.008 0.00175 1 0.28914 1 0.089819 1 0.062819 1 0.00329 1 0.04223 1 0.00136 0.962 2e-05 0.0152 9.9999e-06 0.008 9q loss 169 (41%) 239 9.9999e-06 0.008 4e-05 0.0302 0.02819 1 0.01036 1 0.00046 0.335 9.9999e-06 0.008 0.02702 1 0.00067999 0.492 9.9999e-06 0.008 9.9999e-06 0.008 10p loss 73 (18%) 335 0.03764 1 0.01481 1 0.91075 1 0.26593 1 0.00474 1 0.00412 1 0.54422 1 0.1248 1 0.41508 1 0.34765 1 10q loss 127 (31%) 281 9.9999e-06 0.008 0.00023 0.171 0.51339 1 0.58059 1 0.01773 1 0.15623 1 0.18291 1 0.058939 1 0.25271 1 0.03207 1 11p loss 180 (44%) 228 9.9999e-06 0.008 9.9999e-06 0.008 0.18072 1 0.79944 1 0.00011 0.0821 0.00038 0.277 0.13244 1 0.087929 1 0.00023 0.171 0.00068999 0.497 11q loss 131 (32%) 277 9.9999e-06 0.008 0.00095999 0.687 0.04194 1 0.15627 1 0.04122 1 0.19409 1 0.59351 1 0.49284 1 0.52772 1 0.22824 1 12p loss 53 (13%) 355 0.0074499 1 0.62093 1 0.94403 1 0.47394 1 0.085959 1 0.11744 1 0.52322 1 0.43997 1 0.14266 1 0.2688 1 12q loss 57 (14%) 351 2e-05 0.0152 0.43511 1 0.36685 1 0.40682 1 0.81312 1 0.66396 1 1 1 0.65251 1 0.8283 1 0.068929 1 13q loss 85 (21%) 323 3e-04 0.221 0.16083 1 0.01036 1 0.10283 1 0.03926 1 0.16219 1 0.2402 1 9.9999e-06 0.008 0.01307 1 0.0014 0.988 14q loss 119 (29%) 289 9.9999e-06 0.008 0.64937 1 0.067919 1 0.03751 1 0.090759 1 0.00037 0.27 0.00167 1 0.031 1 0.0075299 1 5.9999e-05 0.0449 15q loss 144 (35%) 264 9.9999e-06 0.008 0.00033 0.242 0.1065 1 0.31513 1 0.34246 1 0.01667 1 0.0153 1 9.9999e-06 0.008 0.01251 1 0.00013 0.0968 16p loss 106 (26%) 302 9.9999e-06 0.008 0.02419 1 0.65817 1 0.60363 1 0.84814 1 0.60451 1 0.31322 1 0.11748 1 0.066299 1 0.01065 1 16q loss 104 (25%) 304 9.9999e-06 0.008 0.02006 1 0.58928 1 0.90285 1 0.49513 1 0.88498 1 0.91482 1 0.068939 1 0.7729 1 0.0075599 1 17p loss 182 (45%) 226 9.9999e-06 0.008 0.64065 1 0.91114 1 0.52992 1 0.44626 1 0.0094199 1 0.6755 1 0.01544 1 0.16308 1 0.00347 1 17q loss 42 (10%) 366 0.00134 0.949 0.70485 1 0.81392 1 0.6969 1 0.56898 1 0.74549 1 0.79362 1 0.77433 1 0.8365 1 0.58182 1 18p loss 98 (24%) 310 0.00067999 0.492 0.46617 1 0.45041 1 0.36452 1 0.59598 1 0.26564 1 0.17075 1 0.83491 1 0.1141 1 0.25646 1 18q loss 144 (35%) 264 0.0051999 1 0.4124 1 0.68255 1 0.74435 1 0.63774 1 0.77664 1 0.00185 1 0.00217 1 0.083319 1 0.33442 1 19p loss 94 (23%) 314 0.00127 0.904 0.52915 1 0.64128 1 0.48963 1 0.092179 1 0.02859 1 0.2562 1 0.30588 1 0.33932 1 0.068559 1 19q loss 57 (14%) 351 0.01663 1 1 1 0.20424 1 0.093499 1 0.39904 1 0.29352 1 0.070359 1 0.62836 1 0.26808 1 0.0188 1 20p loss 33 (8%) 375 0.20623 1 0.03995 1 0.25091 1 0.03763 1 1 1 0.91675 1 0.79488 1 0.95668 1 0.40057 1 0.30354 1 20q loss 16 (4%) 392 0.095599 1 0.04731 1 0.73558 1 0.45957 1 0.48565 1 0.5305 1 0.45459 1 0.63995 1 0.40171 1 0.75089 1 21q loss 77 (19%) 331 0.0344 1 0.10148 1 0.068399 1 0.32996 1 0.00256 1 0.01104 1 0.17291 1 0.12728 1 0.00281 1 0.01835 1 22q loss 159 (39%) 249 9.9999e-06 0.008 0.0051599 1 0.63575 1 0.01647 1 0.01269 1 0.02108 1 0.15261 1 0.00332 1 0.071649 1 3e-05 0.0227 xq loss 78 (19%) 330 0.0063799 1 0.25616 1 0.97071 1 0.81554 1 0.70189 1 0.57851 1 0.069739 1 0.27486 1 0.02273 1 0.01274 1