Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q amp_1p34.2 101 (25%) 307 9.9999e-06 0.007 0.10038 1 0.18208 1 0.50769 1 0.93763 1 0.29016 1 0.0351 1 0.01922 1 0.24209 1 0.01148 1 amp_1q21.3 202 (50%) 206 9.9999e-06 0.007 0.053019 1 0.39166 1 0.72154 1 0.04804 1 0.0072399 1 0.14013 1 0.04308 1 0.621 1 0.00373 1 amp_1q23.3 216 (53%) 192 9.9999e-06 0.007 0.00383 1 0.55171 1 0.88554 1 0.10629 1 0.0096099 1 0.00203 1 0.00319 1 0.04134 1 0.00149 0.84 amp_2p25.1 152 (37%) 256 9.9999e-06 0.007 0.00024 0.142 0.80098 1 0.61286 1 0.03651 1 0.00139 0.785 0.02379 1 0.01635 1 0.01632 1 3e-05 0.0187 amp_3p25.2 190 (47%) 218 9.9999e-06 0.007 0.053149 1 0.079019 1 0.01094 1 9.9999e-06 0.007 9.9999e-06 0.007 0.00019 0.114 9.9999e-06 0.007 9.9999e-06 0.007 9.9999e-06 0.007 amp_3q26.33 218 (53%) 190 9.9999e-06 0.007 0.52166 1 0.35317 1 0.092739 1 0.31512 1 0.13193 1 0.54014 1 0.0056399 1 0.1809 1 9.9999e-06 0.007 amp_4p16.3 74 (18%) 334 0.21258 1 0.00027 0.158 0.03384 1 0.02658 1 0.00043 0.248 2e-05 0.0125 9.9999e-06 0.007 0.02576 1 0.058079 1 0.02204 1 amp_4q13.3 62 (15%) 346 5.9999e-05 0.0368 0.02692 1 0.58225 1 0.70246 1 0.26463 1 0.50168 1 0.0094499 1 0.066769 1 0.065519 1 0.04346 1 amp_5p15.33 206 (50%) 202 9.9999e-06 0.007 0.16467 1 0.02159 1 0.17764 1 0.61554 1 0.076499 1 0.3909 1 3e-05 0.0187 0.32862 1 0.00085999 0.489 amp_6p22.3 171 (42%) 237 9.9999e-06 0.007 0.10272 1 0.33581 1 0.43324 1 0.42841 1 0.23401 1 0.070839 1 0.26183 1 0.26032 1 9.9999e-06 0.007 amp_6q21 34 (8%) 374 0.00233 1 0.82445 1 0.51431 1 0.079229 1 0.3937 1 0.25461 1 0.82066 1 0.87527 1 0.38168 1 0.18548 1 amp_6q23.3 46 (11%) 362 0.00046 0.264 0.81094 1 0.9448 1 0.069569 1 0.3042 1 0.67057 1 0.13981 1 0.099769 1 0.14788 1 0.12573 1 amp_7p21.1 201 (49%) 207 9.9999e-06 0.007 0.02324 1 0.13324 1 0.31733 1 0.67339 1 0.04398 1 0.17103 1 0.0069699 1 0.40075 1 9.9999e-06 0.007 amp_7p11.2 190 (47%) 218 9.9999e-06 0.007 0.02793 1 0.089789 1 0.59893 1 0.72284 1 0.16587 1 0.51394 1 0.0364 1 0.17026 1 5e-05 0.0307 amp_8p11.23 124 (30%) 284 9.9999e-06 0.007 0.094899 1 0.74873 1 0.79117 1 0.65846 1 0.32316 1 0.02864 1 0.51292 1 0.68105 1 0.9527 1 amp_8q22.3 264 (65%) 144 9.9999e-06 0.007 0.00208 1 0.02428 1 0.19024 1 0.23087 1 0.25942 1 0.01916 1 0.0059699 1 0.071959 1 8.9999e-05 0.0548 amp_9p24.1 88 (22%) 320 9.9999e-06 0.007 0.02544 1 0.67398 1 0.32616 1 0.11217 1 0.03809 1 0.69304 1 0.04422 1 0.00012 0.0725 6.9999e-05 0.0427 amp_10p14 182 (45%) 226 9.9999e-06 0.007 0.29376 1 0.3547 1 0.42165 1 0.16786 1 0.00029 0.17 0.10328 1 0.15443 1 0.45281 1 9.9999e-06 0.007 amp_11p13 51 (12%) 357 9.9999e-06 0.007 0.0050199 1 0.0331 1 0.00338 1 0.18465 1 0.01359 1 0.25274 1 0.1181 1 0.052259 1 0.00295 1 amp_11q13.3 135 (33%) 273 9.9999e-06 0.007 0.30943 1 0.23232 1 0.077889 1 0.071049 1 0.03049 1 0.3752 1 0.17427 1 0.32986 1 0.71123 1 amp_11q22.2 71 (17%) 337 0.00012 0.0725 0.27477 1 0.73351 1 0.41163 1 0.84733 1 0.03185 1 0.04229 1 0.02266 1 0.00038 0.221 0.02081 1 amp_12p12.1 132 (32%) 276 2e-05 0.0125 0.04586 1 0.69244 1 0.46948 1 0.53257 1 0.37566 1 0.82158 1 0.02771 1 0.074909 1 0.03855 1 amp_12q15 118 (29%) 290 0.00013 0.0783 0.41039 1 0.03787 1 0.01965 1 0.00217 1 0.00296 1 0.21516 1 0.02107 1 0.0075499 1 0.00044 0.253 amp_13q22.1 128 (31%) 280 9.9999e-05 0.0607 0.35198 1 0.96191 1 0.84937 1 0.97775 1 0.61067 1 0.87734 1 0.55641 1 0.73189 1 0.22412 1 amp_16p13.2 87 (21%) 321 9.9999e-06 0.007 0.12166 1 0.79283 1 0.89883 1 0.51404 1 0.18103 1 0.17958 1 0.071749 1 0.2292 1 0.02247 1 amp_16p11.2 97 (24%) 311 3e-05 0.0187 0.14934 1 0.46605 1 0.36933 1 0.93353 1 0.44253 1 0.24773 1 0.31142 1 0.95722 1 0.071949 1 amp_16q22.1 108 (26%) 300 0.00371 1 0.2757 1 0.04286 1 0.02354 1 0.03171 1 0.03749 1 0.04314 1 0.0084499 1 0.15263 1 0.0071199 1 amp_17p11.2 87 (21%) 321 0.00354 1 0.12895 1 0.68156 1 0.94617 1 0.074919 1 0.41999 1 0.63693 1 0.84394 1 0.53146 1 0.34214 1 amp_17q11.2 174 (43%) 234 9.9999e-06 0.007 0.00095999 0.544 0.03213 1 0.087989 1 8.9999e-05 0.0548 0.00234 1 0.04568 1 0.01195 1 0.00368 1 9.9999e-06 0.007 amp_17q12 165 (40%) 243 9.9999e-06 0.007 0.02714 1 0.13171 1 0.03692 1 0.00296 1 0.068779 1 0.00461 1 0.03534 1 0.01863 1 9.9999e-06 0.007 amp_17q23.3 194 (48%) 214 9.9999e-06 0.007 0.075959 1 0.10765 1 0.14006 1 0.29738 1 0.69331 1 0.18408 1 0.46872 1 0.14542 1 0.00015 0.09 amp_19q12 165 (40%) 243 9.9999e-06 0.007 0.55575 1 0.7529 1 0.78127 1 0.29915 1 0.10563 1 0.2222 1 0.0106 1 0.1576 1 0.02633 1 amp_19q13.43 155 (38%) 253 9.9999e-06 0.007 0.098839 1 0.16824 1 0.30385 1 0.67638 1 0.89792 1 0.41848 1 0.00263 1 0.01673 1 0.00281 1 amp_20q11.21 263 (64%) 145 9.9999e-06 0.007 0.12871 1 0.71246 1 0.054479 1 0.68234 1 0.03545 1 0.34382 1 0.03082 1 0.19496 1 0.00081999 0.467 amp_22q12.2 87 (21%) 321 9.9999e-06 0.007 0.00339 1 0.41572 1 0.76218 1 0.03973 1 0.21573 1 0.12889 1 0.25606 1 0.47772 1 0.04837 1 del_1p36.11 91 (22%) 317 0.34911 1 0.04433 1 0.16524 1 0.024 1 0.83172 1 0.88846 1 0.70468 1 0.04726 1 0.13297 1 0.25332 1 del_1q32.1 71 (17%) 337 0.00024 0.142 0.40883 1 0.35255 1 0.60493 1 0.17131 1 0.067079 1 0.55041 1 0.27666 1 0.40188 1 0.13145 1 del_2q22.1 134 (33%) 274 0.00042 0.242 0.0069999 1 0.27438 1 0.94252 1 0.098569 1 0.2164 1 0.060009 1 0.25024 1 0.18677 1 0.0088499 1 del_2q34 174 (43%) 234 9.9999e-06 0.007 0.01501 1 0.75071 1 0.58193 1 0.46051 1 0.45292 1 0.10954 1 0.53302 1 0.487 1 0.00066999 0.384 del_2q37.1 207 (51%) 201 9.9999e-06 0.007 0.00023 0.136 0.59321 1 0.44182 1 0.10004 1 0.089849 1 0.02197 1 0.060609 1 0.18445 1 0.0054899 1 del_3p14.2 117 (29%) 291 0.00011 0.0665 0.1078 1 0.03429 1 0.01752 1 9.9999e-06 0.007 9.9999e-06 0.007 0.88143 1 4e-05 0.0246 5.9999e-05 0.0368 9.9999e-06 0.007 del_4q22.1 162 (40%) 246 9.9999e-06 0.007 0.0083799 1 0.5093 1 0.50484 1 0.067929 1 0.01919 1 0.89733 1 0.0074499 1 0.02419 1 0.01394 1 del_4q34.2 177 (43%) 231 9.9999e-06 0.007 0.03989 1 0.48689 1 0.77181 1 0.36841 1 0.20068 1 0.29224 1 0.063689 1 0.48768 1 0.00079999 0.457 del_5q12.1 202 (50%) 206 9.9999e-06 0.007 0.01496 1 0.93525 1 0.57321 1 0.25473 1 0.0087999 1 0.02235 1 0.00013 0.0783 0.060329 1 0.00092999 0.528 del_6p25.3 106 (26%) 302 9.9999e-06 0.007 0.0482 1 0.91186 1 0.94702 1 0.54251 1 0.052729 1 0.25338 1 0.03116 1 0.051859 1 0.0076499 1 del_6q21 190 (47%) 218 9.9999e-06 0.007 0.04903 1 0.8828 1 0.47038 1 0.49109 1 0.076649 1 0.0152 1 0.00022 0.131 0.23845 1 9.9999e-06 0.007 del_6q27 190 (47%) 218 9.9999e-06 0.007 0.02694 1 0.65835 1 0.43381 1 0.41701 1 0.02004 1 0.02221 1 2e-05 0.0125 0.37564 1 9.9999e-06 0.007 del_7q36.3 59 (14%) 349 4e-04 0.232 0.61695 1 0.13666 1 0.1325 1 0.4374 1 0.2958 1 0.46588 1 0.00157 0.884 0.054579 1 0.00335 1 del_8p23.1 245 (60%) 163 9.9999e-06 0.007 3e-04 0.175 0.59047 1 0.17713 1 0.26917 1 0.03854 1 0.073379 1 0.02648 1 0.16092 1 0.072379 1 del_9p23 177 (43%) 231 9.9999e-06 0.007 0.02681 1 0.21949 1 0.20499 1 0.26751 1 0.03587 1 0.065309 1 0.01671 1 3e-05 0.0187 0.00078999 0.452 del_9p21.3 239 (59%) 169 9.9999e-06 0.007 0.26624 1 0.45077 1 0.0096499 1 0.23223 1 0.12 1 0.15275 1 0.094379 1 0.03686 1 9.9999e-05 0.0607 del_9q33.2 168 (41%) 240 9.9999e-06 0.007 9.9999e-06 0.007 0.067169 1 0.00298 1 9.9999e-06 0.007 9.9999e-06 0.007 4e-04 0.232 0.00032 0.186 9.9999e-06 0.007 9.9999e-06 0.007 del_10p11.21 74 (18%) 334 0.081969 1 0.39508 1 0.53502 1 0.24396 1 0.00322 1 0.00311 1 0.7815 1 0.057309 1 0.37309 1 0.50155 1 del_10q23.31 167 (41%) 241 9.9999e-06 0.007 0.053619 1 0.62749 1 0.59373 1 0.12837 1 0.89528 1 0.32492 1 0.092959 1 0.60961 1 0.064569 1 del_11p15.5 211 (52%) 197 9.9999e-06 0.007 3e-04 0.175 0.36524 1 0.24221 1 0.00222 1 0.00026 0.153 0.02148 1 0.29861 1 0.01275 1 0.01208 1 del_11q23.3 156 (38%) 252 2e-04 0.119 0.00312 1 0.65598 1 0.70409 1 0.069389 1 0.25711 1 0.23562 1 0.17303 1 0.58428 1 0.51909 1 del_11q25 144 (35%) 264 3e-05 0.0187 0.0077599 1 0.77319 1 0.62054 1 0.051259 1 0.25737 1 0.381 1 0.19742 1 0.47353 1 0.29198 1 del_12p13.1 68 (17%) 340 0.00343 1 0.072799 1 0.78045 1 0.66245 1 0.0073099 1 0.00025 0.147 0.57112 1 0.61895 1 0.0165 1 0.21166 1 del_12q24.33 88 (22%) 320 2e-05 0.0125 0.92904 1 0.91534 1 0.32025 1 0.60427 1 0.65068 1 1 1 0.62665 1 0.98197 1 0.24206 1 del_13q14.2 156 (38%) 252 9.9999e-06 0.007 0.25358 1 0.0078299 1 0.00359 1 0.01284 1 0.03324 1 0.5363 1 3e-04 0.175 0.0056199 1 9.9999e-06 0.007 del_14q24.1 137 (34%) 271 9.9999e-06 0.007 0.12363 1 0.3923 1 0.34608 1 0.00365 1 9.9999e-06 0.007 0.0070799 1 0.00102 0.577 0.00333 1 3e-05 0.0187 del_15q13.1 159 (39%) 249 9.9999e-06 0.007 0.0065399 1 0.31726 1 0.56877 1 0.70117 1 0.094609 1 0.02624 1 5.9999e-05 0.0368 0.02539 1 9.9999e-06 0.007 del_16p13.3 173 (42%) 235 9.9999e-06 0.007 0.0079499 1 0.21164 1 0.46764 1 0.64389 1 0.8554 1 0.70263 1 0.04325 1 0.52184 1 0.01214 1 del_16q23.1 119 (29%) 289 9.9999e-06 0.007 0.01507 1 0.50165 1 0.063689 1 0.057219 1 0.27498 1 0.13105 1 0.0251 1 0.085189 1 5e-05 0.0307 del_17p12 209 (51%) 199 9.9999e-06 0.007 0.03432 1 0.20083 1 0.60928 1 0.28852 1 0.00351 1 0.60514 1 0.00019 0.114 0.35855 1 0.00019 0.114 del_18q23 178 (44%) 230 0.00041 0.237 0.10548 1 0.63163 1 0.78498 1 0.21443 1 0.61646 1 9.9999e-06 0.007 9.9999e-06 0.007 0.033 1 0.0067199 1 del_19p13.3 145 (36%) 263 9.9999e-06 0.007 0.82199 1 0.93786 1 0.56299 1 0.02721 1 0.0053099 1 0.33372 1 0.0091799 1 0.21086 1 2e-04 0.119 del_22q13.32 187 (46%) 221 9.9999e-06 0.007 0.00023 0.136 0.54898 1 0.01622 1 0.01412 1 0.0301 1 0.28731 1 0.00159 0.894 0.0090499 1 9.9999e-06 0.007 del_xp11.3 92 (23%) 316 0.093189 1 0.39552 1 0.73531 1 0.61826 1 0.28198 1 0.94818 1 0.10613 1 0.29016 1 0.51828 1 0.0329 1 del_xq21.33 84 (21%) 324 0.01671 1 0.055069 1 0.98023 1 0.4359 1 0.054679 1 0.19908 1 0.088169 1 0.050919 1 0.01134 1 0.01768 1