Hybridization REF	p	difference	q	subclass
Composite Element REF	p	difference	q	subclass
ERBB2|HER2	4.09653386772975e-16	1.86452587525806	3.66639781161813e-14	1
GATA3|GATA3	1.13757306724168e-12	1.46687145359677	6.78751930120869e-11	1
INPP4B|INPP4B	6.83961592856474e-10	1.42943658337097	9.41762500933145e-09	1
VHL|VHL	1.3711407672559e-05	1.32598761837097	5.63128433894134e-05	1
CDH1|E-CADHERIN	2.53794804185949e-09	1.32121660687097	3.24494785352035e-08	1
FASN|FASN	9.35161601378885e-12	1.30909768696774	2.98116761561533e-10	1
RB1|RB_PS807_S811	2.83455849415502e-11	1.12965894527419	6.34232463067186e-10	1
CTNNB1|BETA-CATENIN	1.12853316665125e-07	1.01744668748387	9.18215621957153e-07	1
SRC|SRC_PY527	5.47070162940332e-06	0.974868704112903	2.7978731190377e-05	1
ACACA ACACB|ACC_PS79	8.47292517713212e-11	0.946914596645161	1.51665360670665e-09	1
SRC|SRC	3.69651773582724e-11	0.920623524177419	7.35196305236751e-10	1
BRAF|RAF-B	1.10359144332335e-08	0.903240190016129	1.09746037974933e-07	1
CLDN7|CLAUDIN-7	1.06187958209329e-05	0.875955248209677	4.63601085840729e-05	1
RBM15|RBM15	2.85637703799216e-08	0.837033776532258	2.55645744900298e-07	1
PDCD4|PDCD4	2.35335569831066e-05	0.735563273112903	9.36112599994685e-05	1
EIF4EBP1|4E-BP1_PT37_T46	9.59517643539256e-05	0.70384523966129	0.000318062329988013	1
ACACA|ACC1	4.86954587573483e-06	0.686657498516129	2.56367268163687e-05	1
BAP1|BAP1-C-4	3.04196851585171e-09	0.632677660532258	3.63008242891637e-08	1
ERBB2|HER2_PY1248	0.000399338870361974	0.585876706806452	0.00111247053563074	1
TP53BP1|53BP1	2.54834645659801e-07	0.582026893032258	1.82461606292418e-06	1
PTEN|PTEN	9.09017957442005e-06	0.575734046596774	4.06785535955297e-05	1
PKC|PKC-PAN_BETAII_PS660	3.36222612324627e-05	0.573483592112903	0.000122824178787976	1
ERBB3|HER3	0.000225491445651824	0.517809434822581	0.000672716146194608	1
XRCC5|KU80	7.69979618237806e-06	0.49768499416129	3.72800201818442e-05	1
RAB25|RAB25	9.86471385811682e-05	0.46601203766129	0.000321051596473256	1
MAPK14|P38_PT180_Y182	0.0100356034313207	0.457478950370968	0.0216430483639326	1
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	0.00158115367625512	0.447693766290323	0.00393092372291203	1
GSK3A GSK3B|GSK3_PS9	0.000523352118418292	0.420959897	0.00137764748818933	1
RPS6|S6	0.000159434421639273	0.411901080677419	0.00049204761161086	1
AR|AR	0.0131268700820309	0.380791702032258	0.0267012470986765	1
STAT5A|STAT5-ALPHA	0.0121252488809889	0.368185018096774	0.0254681005242223	1
EEF2K|EEF2K	0.00612022212858589	0.364018092048387	0.0142275293638555	1
PXN|PAXILLIN	0.00632493676916993	0.35782814816129	0.0145149189959156	1
CHEK1|CHK1_PS345	2.89434585605149e-07	0.35525608266129	1.99264580089699e-06	1
SMAD3|SMAD3	3.72114653532089e-06	0.337191129064516	2.14866203168529e-05	1
BAK1|BAK	5.17302018851682e-05	0.337144013467742	0.000178071271873944	1
TSC2|TUBERIN	0.0123783505341192	0.314998449354839	0.0254681005242223	1
CHEK2|CHK2	0.000402414191208157	0.308437305645161	0.00111247053563074	1
NFKB1|NF-KB-P65_PS536	0.0416183497602686	0.302032508080645	0.0702800434630951	1
AKT1S1|PRAS40_PT246	1.72444500751508e-06	0.294142250225806	1.06439881498345e-05	1
BAD|BAD_PS112	5.9099774943616e-05	0.287840937354839	0.000199601126696363	1
RPS6KB1|P70S6K	0.000390372828482993	0.285049841290322	0.00111247053563074	1
RPS6|S6_PS240_S244	0.0489208587983633	0.283983193629032	0.0803379240817159	1
SRC|SRC_PY416	0.0224136255356705	0.274996751645161	0.0420972471914239	1
EEF2|EEF2	0.0163469218091058	0.268025855129032	0.0321549341080213	1
CCNE2|CYCLIN_E2	0.00040396974757541	0.252349505612903	0.00111247053563074	1
NF2|NF2	0.00346260876478122	0.228900936741935	0.00826409291861118	1
ESR1|ER-ALPHA_PS118	1.93670340626935e-06	0.220783335064516	1.15556636574071e-05	1
EIF4G1|EIF4G	0.0155752521599149	0.219662032612903	0.0309774459624974	1
IRS1|IRS1	0.0191575873582898	0.215764037903226	0.0372740014905856	1
FRAP1|MTOR	0.00277824692999411	0.21043921732258	0.00672035406039116	1
SCD1|SCD1	0.0201670120261638	0.210228890290323	0.0388160769105733	1
MYH9|MYOSIN-IIA_PS1943	0.0273840188968523	0.176272715177419	0.0500177488013935	1
RAD50|RAD50	0.0072182731429269	0.174588163693548	0.0163553277542268	1
SFRS1|SF2	0.00895558653690094	0.164823760080645	0.019549390123235	1
PRKAA1|AMPK_ALPHA	0.0352828039090995	0.158040011225806	0.0613167174730952	1
RPS6KA1|P90RSK	0.0313896554253103	0.154638083790323	0.055631171496342	1
YWHAE|14-3-3_EPSILON	0.0409532143045249	-0.0705288347903225	0.069956461518503	1
NRAS|N-RAS	0.0235395556486702	-0.0829286403387097	0.0434389738258966	1
CDKN1B|P27_PT198	0.0308612266941388	-0.0892881306935485	0.0552415957825085	1
RAF1|C-RAF_PS338	0.0341099603062428	-0.094938208516129	0.0598596362237006	1
CDKN1B|P27_PT157	0.000112649108043065	-0.100210203258064	0.000360074827494797	1
FOXO3|FOX03A	0.0423289662989244	-0.100610091677419	0.0708120090421259	1
MET|C-MET_PY1235	0.00252249680553349	-0.101306985580645	0.00618530038617116	1
BECN1|BECLIN	0.00844955559730808	-0.114724635290323	0.0186724747150388	1
PDK1|PDK1	0.00736844598491923	-0.115774822290323	0.0164868978912568	1
RPS6KA1|P90RSK_PT359_S363	0.0463916400729598	-0.11676351966129	0.0768898478987019	1
SMAD4|SMAD4	0.0115902214355664	-0.127756132354839	0.0246982099638855	1
PGR|PR	0.000752420390881207	-0.131733286177419	0.00192404642811051	1
PARK7|DJ-1	0.02257729458311	-0.135542697145161	0.0420972471914239	1
BAX|BAX	0.0284908091661616	-0.155809561967742	0.0515136852600296	1
YWHAB|14-3-3_BETA	5.16003314434699e-05	-0.15928664283871	0.000178071271873944	1
C12ORF5|TIGAR	0.000206462430386616	-0.163468072387097	0.000626386017613632	1
CCND1|CYCLIN_D1	3.1904135553807e-05	-0.169267989580645	0.000118975838836072	1
BID|BID	0.000928850862108661	-0.180301394725806	0.00234175076503451	1
CDH3|P-CADHERIN	2.68366616439395e-05	-0.183313293016129	0.000104429618136199	1
ANXA7 |ANNEXIN_VII	0.000258845484066874	-0.183943625435484	0.000759562977835581	1
PIK3R1|PI3K-P85	0.0122680612920586	-0.188765487467742	0.0254681005242223	1
DVL3|DVL3	0.0410359131812448	-0.190966766064516	0.069956461518503	1
STAT3|STAT3_PY705	0.0218366934299066	-0.21266085483871	0.0415826396165243	1
YBX1|YB-1	1.21848119354433e-05	-0.224130190354839	5.19305080105798e-05	1
ESR1|ER-ALPHA	0.00360360265631009	-0.227132590032258	0.00848743257209876	1
MAPK14|P38_MAPK	0.000531584605258711	-0.241246006258064	0.00137903832378709	1
YAP1|YAP	0.000445855780952743	-0.243226478725806	0.0012092149210688	1
CDC2|CDK1	4.95981796549782e-05	-0.252064448306452	0.000177561483164822	1
PECAM1|CD31	0.000124997215055106	-0.264425540919355	0.000392535113944982	1
MRE11A|MRE11	1.34395630046074e-10	-0.270955088112903	2.18698343438611e-09	1
NRG1|HEREGULIN	3.87290616334282e-06	-0.286129444822581	2.16640688511989e-05	1
EGFR|EGFR	0.0149329541224172	-0.287792018145161	0.0300336942462099	1
STK11|LKB1	3.34543033907403e-12	-0.358406408225806	1.49708007673563e-10	1
PEA15|PEA15	8.12246249772024e-06	-0.370561582612903	3.72800201818442e-05	1
CDH2|N-CADHERIN	5.96817668091161e-07	-0.371052329435484	3.95668009586362e-06	1
BCL2L11|BIM	0.000491263613609402	-0.382457972177419	0.00131248040053855	1
WWTR1|TAZ	3.74322231759281e-09	-0.385592848516129	4.18772996780696e-08	1
STMN1|STATHMIN	6.33503893770557e-09	-0.38808730433871	6.67042335205469e-08	1
CHEK1|CHK1	2.04054067547067e-07	-0.420162353483871	1.588072960475e-06	1
BCL2|BCL-2	1.6390054007957e-08	-0.421984995532258	1.54411561443384e-07	1
LCK|LCK	1.38422631795206e-05	-0.425443636258065	5.63128433894134e-05	1
ACVRL1|ACVRL1	1.38290365414438e-16	-0.509229894887097	2.47539754091844e-14	1
MYC|C-MYC	9.99274061100109e-12	-0.632469895080645	2.98116761561533e-10	1
TGM2|TRANSGLUTAMINASE	3.09520120243581e-08	-0.744261369048387	2.6382905487429e-07	1
COL6A1|COLLAGEN_VI	2.04674197895149e-11	-0.760067586177419	5.23381163189024e-10	1
CASP7|CASPASE-7_CLEAVEDD198	4.47939859649807e-06	-0.853620254290323	2.42973439022168e-05	1
HSPA1A|HSP70	2.29643382316613e-07	-0.86915464783871	1.71275689311141e-06	1
SERPINE1|PAI-1	3.15799905476607e-05	-0.957428891516129	0.000118975838836072	1
RICTOR|RICTOR	7.75534250975394e-06	-1.09133280414516	3.72800201818442e-05	1
CAV1|CAVEOLIN-1	8.00459118597391e-06	-1.09322491348387	3.72800201818442e-05	1
FN1|FIBRONECTIN	1.80314736950189e-10	-1.26780328191935	2.68969482617365e-09	1
MYH11|MYH11	1.34203388665839e-06	-1.53341962953226	8.57943091828042e-06	1
MYH11|MYH11	3.1214641512849e-23	3.02112084867143	5.58742083079997e-21	2
RICTOR|RICTOR	1.8554582909869e-13	2.92605654314286	1.07896086100837e-11	2
CAV1|CAVEOLIN-1	1.1316949002274e-11	1.52742459091801	2.89390553058149e-10	2
TGM2|TRANSGLUTAMINASE	7.50376262778493e-07	0.906597339232919	6.39606433511192e-06	2
KDR|VEGFR2	5.94643525549753e-11	0.866672337137888	1.33051488841757e-09	2
YAP1|YAP_PS127	2.08471630377657e-07	0.810868298330435	2.33227636485004e-06	2
PRKCA |PKC-ALPHA_PS657	3.92445383650151e-09	0.746149024293168	5.92006795981656e-08	2
COL6A1|COLLAGEN_VI	8.96867352593576e-07	0.737963806231056	7.2972389142841e-06	2
PRKAA1|AMPK_PT172	1.52371712167666e-06	0.669471727549069	1.18584941208749e-05	2
PRKCA |PKC-ALPHA	1.96601642898789e-07	0.667828939006832	2.33227636485004e-06	2
FN1|FIBRONECTIN	0.000272934615377737	0.635182894390683	0.00113616967796779	2
ATM|ATM	0.00068244488215425	0.563113079618633	0.00254407615220323	2
HSPA1A|HSP70	0.00466234121723108	0.55897159545031	0.0122729276159465	2
TSC1|TSC1	1.34196420749595e-12	0.558749254240372	4.8042318628355e-11	2
PEA15|PEA15	5.25246353297108e-10	0.49792264792795	9.40190972401823e-09	2
ACVRL1|ACVRL1	2.81501395381978e-08	0.480572804514286	3.87605767487493e-07	2
KIT|C-KIT	0.000310867313464558	0.437688367214907	0.0012365610913368	2
PIK3R1|PI3K-P85	3.75759402633664e-07	0.398967643730435	3.7367185039681e-06	2
BCL2|BCL-2	2.59345983113878e-05	0.38419176777764	0.000154743103257947	2
LCK|LCK	0.001566549450652	0.363167003459627	0.00509840639394015	2
AKT1 AKT2 AKT3|AKT	0.000452290259881437	0.33704691811677	0.00172255226635696	2
PARK7|DJ-1	7.13430360986253e-07	0.299964068603106	6.38520173082696e-06	2
MYC|C-MYC	0.0043200462968803	0.290218567959006	0.0115416162259936	2
STAT3|STAT3_PY705	0.00416673693496077	0.28134508018882	0.011300695626636	2
CDC2|CDK1	0.00227014266114482	0.255227796260248	0.00700612993698143	2
YAP1|YAP	0.00708240930109116	0.254445710791925	0.0171317738499367	2
RPTOR|RAPTOR	0.000151459529437325	0.240795788604348	0.000695160404340543	2
MAPK9|JNK2	0.000810211340388453	0.224358307946584	0.00290055659859066	2
WWTR1|TAZ	0.000298569583129883	0.222677358712422	0.00121463534955111	2
MAPK14|P38_MAPK	0.0031309539947669	0.196921902678261	0.00896386110209825	2
ESR1|ER-ALPHA	0.0248355373743153	0.19405621821677	0.0505177407954823	2
STK11|LKB1	0.000356079247176092	0.183339346997516	0.00138561272270697	2
CDKN1B|P27	0.00381417872068994	0.179683391945963	0.0105036614000538	2
CDH3|P-CADHERIN	5.66742162972523e-05	0.172907627501242	0.000298373079917887	2
PGR|PR	0.00133143933813951	0.164227056052795	0.0044967479533391	2
MRE11A|MRE11	0.00264973624715339	0.151717182044099	0.00803903030916029	2
PRKAA1|AMPK_ALPHA	0.0342922187897802	0.139744139232298	0.065301140035858	2
ANXA7 |ANNEXIN_VII	0.00683780185697855	0.1273301588	0.016940658477259	2
PDK1|PDK1_PS241	0.0480451768866113	0.127134854348447	0.0868695622495295	2
YBX1|YB-1	0.022822944972628	0.110202229667702	0.04695755344943	2
BECN1|BECLIN	0.0107522944145606	0.107546795895652	0.0243627936734981	2
PRKCD|PKC-DELTA_PS664	0.0316391701269132	0.103700954263975	0.0615588201382333	2
BRCA2|BRCA2	0.0349264519488705	0.0883428009739131	0.0658087884089244	2
TSC2|TUBERIN_PT1462	0.0333091429450791	-0.0846278390670807	0.0641111460985931	2
MS4A1|CD20	0.0155140798150499	-0.0870201846055901	0.0342842010727646	2
ERBB3|HER3_PY1298	0.00473601517943582	-0.104756538967081	0.0122861843060726	2
EGFR|EGFR_PY1173	0.00137808848725642	-0.109945438604348	0.00456810813368332	2
ERRFI1|MIG-6	0.00616042073483559	-0.111878665929193	0.0155312015709235	2
SHC1|SHC_PY317	0.0282018041489285	-0.11416159768882	0.0560902549184245	2
SMAD4|SMAD4	0.0100102523368269	-0.117530086727329	0.0229722457473335	2
CDKN1B|P27_PT198	0.00911966928710189	-0.123263728881366	0.0212002701609252	2
EIF4EBP1|4E-BP1_PT70	0.00526292361458167	-0.130505505901242	0.013458047528716	2
CHEK2|CHK2_PT68	0.0069087601611168	-0.13172386817764	0.016940658477259	2
BAD|BAD_PS112	0.0474815585415559	-0.13351749316646	0.0867265201932501	2
RPS6KB1|P70S6K_PT389	0.0184920493434903	-0.137815325769565	0.0394056765771996	2
JUN|C-JUN_PS73	0.000191771265280672	-0.156740894526087	0.000837245280127812	2
CHEK1|CHK1_PS345	0.000696423080770717	-0.168963142264596	0.00254407615220323	2
RAD51|RAD51	0.00320482959274507	-0.174114994843478	0.00896386110209825	2
YBX1|YB-1_PS102	0.00108101096173116	-0.184748775754037	0.00372117234903611	2
RPS6KA1|P90RSK	0.00018810226542882	-0.202640164374534	0.000837245280127812	2
IRS1|IRS1	0.000921186703608819	-0.204852604921118	0.00323318470482311	2
NF2|NF2	5.53777854835558e-05	-0.239475681829814	0.000298373079917887	2
EEF2|EEF2	0.0204353545823511	-0.244283920313664	0.0430344525910688	2
SCD1|SCD1	4.72530389030115e-05	-0.251351240585093	0.000272848192375454	2
RPS6KB1|P70S6K	0.00320495592477256	-0.25587450859441	0.00896386110209825	2
EIF4G1|EIF4G	0.00875051642064257	-0.266145691893789	0.0206097689380924	2
SFRS1|SF2	6.54545712414404e-08	-0.288906865932919	8.36883446586988e-07	2
MYH9|MYOSIN-IIA_PS1943	0.0387747856909314	-0.290026575074534	0.0722988191528825	2
TP53BP1|53BP1	0.0169516298658885	-0.300817121095031	0.0365583342890848	2
SRC|SRC	0.0116368181975963	-0.304926792260249	0.0260373807171217	2
AKT1S1|PRAS40_PT246	3.96876064345244e-09	-0.314835295982609	5.92006795981656e-08	2
RPS6|S6_PS240_S244	0.0310800274279165	-0.339557575100621	0.0611354385670006	2
ESR1|ER-ALPHA_PS118	5.08650890900891e-20	-0.350607322897516	4.55242547356297e-18	2
ERBB2|HER2_PY1248	0.0018386074034522	-0.358753110759006	0.00577387237224463	2
SRC|SRC_PY416	1.35637199096477e-05	-0.387004435784472	8.99224394009977e-05	2
CCNE2|CYCLIN_E2	2.30614479810486e-10	-0.395685461222981	4.58666576511967e-09	2
EIF4EBP1|4E-BP1_PT37_T46	0.0445112070715279	-0.396350942586335	0.0821392377917886	2
CHEK2|CHK2	1.5484990543829e-05	-0.400212133275155	9.89933324051925e-05	2
FOXM1|FOXM1	2.86800163763816e-07	-0.401674663621118	3.0198370184543e-06	2
BAK1|BAK	6.32923216373308e-12	-0.408373139571429	1.88822092884704e-10	2
ACACA ACACB|ACC_PS79	0.00290361703883629	-0.409120343116149	0.00866245749919493	2
SMAD3|SMAD3	2.41108572292373e-13	-0.416090403457143	1.07896086100837e-11	2
GATA3|GATA3	0.0159599468100311	-0.47724875812795	0.0348393960853118	2
BAP1|BAP1-C-4	0.000101168811323355	-0.492357355428572	0.000502943418665988	2
ITGA2|CD49B	0.00013216350195782	-0.510039680903727	0.000622559653959205	2
EEF2K|EEF2K	0.000103960371456098	-0.511895698418013	0.000502943418665988	2
CCNB1|CYCLIN_B1	0.00874721517051603	-0.516180886749068	0.0206097689380924	2
FASN|FASN	0.0209935890138292	-0.539702622530435	0.043695958528784	2
EGFR|EGFR_PY1068	1.20453055519443e-05	-0.54176611767205	8.29272959153088e-05	2
ERBB3|HER3	5.53602506086524e-05	-0.546180851255279	0.000298373079917887	2
RPS6|S6	3.72641402608915e-06	-0.564763080296273	2.77928379445816e-05	2
PTEN|PTEN	6.69916208404274e-06	-0.596251229278261	4.7966000521746e-05	2
ERBB2|HER2	0.0257018886962763	-0.603839205356522	0.0516925626588029	2
TRFC|TRFC	0.00303644331023547	-0.664605084640994	0.00891021889396966	2
CTNNB1|BETA-CATENIN	0.00183496116129426	-0.677069176850932	0.00577387237224463	2
RB1|RB_PS807_S811	1.74330709719297e-05	-0.688356396128571	0.00010760412772329	2
CLDN7|CLAUDIN-7	6.21531538819376e-05	-0.911573998954037	0.000317868986996195	2
RBM15|RBM15	6.07717086099781e-07	-1.0402757370528	5.72533465325583e-06	2
CDH1|E-CADHERIN	0.000265253773887453	-1.21532433573106	0.00113048632204414	2
CCNB1|CYCLIN_B1	1.49044816134235e-07	1.02444819835119	7.44444841445932e-06	3
CASP7|CASPASE-7_CLEAVEDD198	0.000233949524388607	0.950200574095238	0.00182073760285046	3
RBM15|RBM15	2.82811631469871e-08	0.821619286634921	3.24759777315928e-06	3
GAPDH|GAPDH	0.000590876823007855	0.713254613236111	0.00311595448053803	3
CTNNB1|BETA-CATENIN	0.00267844125160016	0.67096244940873	0.0102008720007751	3
SYK|SYK	0.000230586477653197	0.606558210956349	0.00182073760285046	3
EIF4G1|EIF4G	1.66356389149929e-07	0.600638526638889	7.44444841445932e-06	3
DVL3|DVL3	3.31189389549804e-05	0.585386087787698	0.000481357725581092	3
EGFR|EGFR	0.00275853805504142	0.574377443015873	0.010287048163592	3
BAP1|BAP1-C-4	1.98263605862752e-06	0.537146893746032	3.94324282771473e-05	3
FOXM1|FOXM1	0.000378520177648167	0.530006351361111	0.0023967524250254	3
RPS6|S6	4.7527579948831e-07	0.529855324200397	1.36094596424668e-05	3
XRCC5|KU80	4.31664532941209e-05	0.497343618432539	0.000515119675976509	3
AKT1 AKT2 AKT3|AKT	4.6970357720546e-06	0.476854970291667	8.40769403197773e-05	3
EEF2K|EEF2K	0.00375453972283459	0.474036057486111	0.0126407349417787	3
PTEN|PTEN	9.12291300438171e-05	0.469211490011905	0.000859474435675961	3
BCL2L11|BIM	0.000206560689991839	0.461513433053571	0.0017606839765971	3
TSC2|TUBERIN	0.000418635258047178	0.444646204819444	0.0024978570396815	3
ATM|ATM	0.0253260472832769	0.442822952390873	0.0604448328494209	3
EIF4EBP1|4E-BP1	0.000785085559539357	0.432288991636905	0.00401515186164414	3
TP53BP1|53BP1	0.00172754290284439	0.427437789527778	0.00736262332402728	3
RPS6KB1|P70S6K	1.22170848028906e-06	0.420397085392857	2.73357272464677e-05	3
STAT5A|STAT5-ALPHA	0.011052433514491	0.411757864146826	0.030912274985842	3
PRKAA1|AMPK_PT172	0.0266375516179638	0.354684122815476	0.0627384439423095	3
EEF2|EEF2	0.00402759599544554	0.346541021549603	0.0128739229140134	3
PCNA|PCNA	0.000985343681749236	0.319519245031746	0.00464148734297666	3
CCNE2|CYCLIN_E2	0.000825948496336156	0.307676175234127	0.00410679946789366	3
FRAP1|MTOR	0.000283914218216881	0.264470046315476	0.00211752687753424	3
SMAD1|SMAD1	0.0023301484273859	0.261079791121032	0.00906731670656687	3
GSK3A GSK3B|GSK3-ALPHA-BETA	4.04372755391689e-05	0.244523765452381	0.000515119675976509	3
MYH9|MYOSIN-IIA_PS1943	0.0150172824406543	0.232401974875	0.0398004726489446	3
PIK3CA |PI3K-P110-ALPHA	0.00198674564104793	0.230360485950397	0.00790283266105732	3
GAB2|GAB2	0.0487714424069746	0.215295733194445	0.10034584127412	3
TSC1|TSC1	0.0233100416758999	0.196505400343254	0.0563851008106227	3
MAPK9|JNK2	0.0151197326264147	0.192591766315476	0.0398004726489446	3
BRCA2|BRCA2	0.00354184993128729	0.183410476710317	0.0121921372634697	3
MAPK1|ERK2	0.0421156233997532	0.173560743815476	0.0897463879589979	3
NF2|NF2	0.0200495901588387	0.172082395154762	0.0505475582877764	3
BIRC2 |CIAP	0.02112927203547	0.162385156005952	0.0522203003812187	3
RAD51|RAD51	0.0212965470828434	0.127155392992064	0.0522203003812187	3
C12ORF5|TIGAR	0.0349093566368557	0.0873052499246032	0.0790984156708503	3
YWHAE|14-3-3_EPSILON	0.0439491087884307	-0.0695116169781746	0.0920567879971079	3
CDKN1B|P27_PT157	0.00298568757797994	-0.0821667476309524	0.0106887615291682	3
MRE11A|MRE11	0.0107187546433524	-0.100938505218254	0.0304548743041282	3
IDH3A|IDH3A	0.0373985153534455	-0.104253296075397	0.0826461018304536	3
YWHAB|14-3-3_BETA	0.00292358393319139	-0.108915507571429	0.0106800311028828	3
ACVRL1|ACVRL1	0.0400032825882515	-0.121611221619048	0.0873242388206953	3
JUN|C-JUN_PS73	0.0354296644897933	-0.126975873769841	0.0792738742959125	3
EIF4EBP1|4E-BP1_PS65	0.0302133594245737	-0.132957689525794	0.0693357863717781	3
ARAF|A-RAF_PS299	0.00385398605633167	-0.133612271787698	0.0126407349417787	3
TSC2|TUBERIN_PT1462	0.00134251853163663	-0.138847018196429	0.00600777042907392	3
CHEK1|CHK1_PS345	0.00577573725882965	-0.142993300482143	0.0181378415672019	3
RPS6KA1|P90RSK_PT359_S363	0.00388402470278115	-0.158150019892857	0.0126407349417787	3
BECN1|BECLIN	0.00183881266679556	-0.160381500059524	0.00748062425810012	3
PGR|PR	4.64045418814433e-05	-0.162219047043651	0.000519150812298647	3
RICTOR|RICTOR_PT1135	3.49589409639899e-05	-0.172220543375	0.000481357725581092	3
CDC2|CDK1	0.00867885631188275	-0.17455588984127	0.025056698061726	3
CHEK1|CHK1	0.0171040595146867	-0.175589513644841	0.0443714007699843	3
AKT1S1|PRAS40_PT246	0.000586538351352095	-0.184159883335317	0.00311595448053803	3
PRKCD|PKC-DELTA_PS664	0.000381226294820862	-0.192483388914683	0.0023967524250254	3
CDKN1B|P27	0.00181344263647813	-0.215492500515873	0.00748062425810012	3
RPS6KB1|P70S6K_PT389	0.000129818205056175	-0.233511312386905	0.00116187293525277	3
RAB25|RAB25	0.0407309067078502	-0.276050635095238	0.0878413530205444	3
KIT|C-KIT	0.044228400937158	-0.279366344652778	0.0920567879971079	3
MAP2K1|MEK1_PS217_S221	6.11792397935164e-05	-0.290790762589286	0.000619224473594237	3
RAB11A RAB11B|RAB11	4.62506832416793e-07	-0.332840705019841	1.36094596424668e-05	3
MAPK8|JNK_PT183_PT185	3.62860086386512e-08	-0.333494483630952	3.24759777315928e-06	3
AR|AR	0.00799934458898609	-0.376162979428571	0.0242691979903137	3
AKT1 AKT2 AKT3|AKT_PS473	0.0115003130006824	-0.377914118674603	0.0316700927249561	3
SRC|SRC_PY416	0.000854979751741492	-0.383691122878968	0.00413625339356019	3
GSK3A GSK3B|GSK3_PS9	0.00773526702038799	-0.38522364203373	0.0238726344249905	3
PDCD4|PDCD4	0.018929722986045	-0.395018029019841	0.0484060059214579	3
COL6A1|COLLAGEN_VI	0.00341299161133007	-0.405406038944444	0.0119789313417271	3
ERBB2|HER2_PY1248	0.000385398699162699	-0.410396202871032	0.0023967524250254	3
AKT1 AKT2 AKT3|AKT_PT308	0.000359136660703294	-0.451571670220238	0.0023967524250254	3
CAV1|CAVEOLIN-1	0.029639830049892	-0.472572827605159	0.0689029815445541	3
SRC|SRC	6.22683828195322e-05	-0.473804576623016	0.000619224473594237	3
YAP1|YAP_PS127	0.0130990364276908	-0.497176627742063	0.0355261745538887	3
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	0.00102122854726355	-0.543897032728174	0.00468717717846604	3
RB1|RB_PS807_S811	0.00855471270531358	-0.569768916875	0.025056698061726	3
MAPK1 MAPK3|MAPK_PT202_Y204	2.16191178934029e-05	-0.574574650972222	0.000351802009356284	3
ERBB2|HER2	0.00170808207772894	-0.581246806099206	0.00736262332402728	3
EIF4EBP1|4E-BP1_PT37_T46	0.000591857275632922	-0.632695037751984	0.00311595448053803	3
GATA3|GATA3	0.00847905853677908	-0.667921417632937	0.025056698061726	3
MAPK14|P38_PT180_Y182	0.000499814183866996	-0.671162742958333	0.00288602383587717	3
INPP4B|INPP4B	0.000388300672210819	-0.931873169400794	0.0023967524250254	3
SRC|SRC_PY527	5.32213505571326e-07	-1.00972696032937	1.36094596424668e-05	3
SERPINE1|PAI-1	4.90947397327376e-06	2.10192732103345	7.98905310196366e-05	5
FN1|FIBRONECTIN	0.000740209004636437	1.27566907874684	0.00331243529574806	5
CHEK1|CHK1	7.58799589195478e-05	1.08021045836618	0.000565938026941627	5
HSPA1A|HSP70	0.00106329744673283	0.921639393617541	0.0042295609547817	5
MYC|C-MYC	0.000360278403681617	0.805823175936709	0.00184256669311456	5
COL6A1|COLLAGEN_VI	0.00105837517766951	0.738017640747739	0.0042295609547817	5
STMN1|STATHMIN	1.32528082011325e-05	0.682793187931284	0.000158150177866848	5
IGFBP2|IGFBP2	0.0417276540786581	0.628769049067812	0.0732279419615667	5
PECAM1|CD31	6.51447358466346e-05	0.585846812051537	0.000539244005787587	5
CDH2|N-CADHERIN	6.92883359391871e-05	0.575507076228752	0.000539244005787587	5
SRC|SRC_PY416	0.0080377254670519	0.546567583826401	0.0204085686109463	5
MAPK1 MAPK3|MAPK_PT202_Y204	0.0106392064220661	0.538304410201627	0.0244156147378184	5
ITGA2|CD49B	0.0166066907400542	0.533407135195298	0.0349717369702318	5
BAX|BAX	0.0010079400964719	0.519294997311935	0.0042295609547817	5
YWHAZ|14-3-3_ZETA	0.013694367856148	0.472185387246836	0.0302628622993888	5
NRG1|HEREGULIN	0.0070856754391184	0.459397898733273	0.0189303866209283	5
SMAD4|SMAD4	0.00644764773027699	0.424087162584087	0.0177558299033782	5
STK11|LKB1	0.00360331743147272	0.41886385264557	0.0117271603678839	5
RPS6KA1|P90RSK_PT359_S363	0.000260952559346774	0.392009862473779	0.00141546994312341	5
MAP2K1|MEK1_PS217_S221	0.00385395458612611	0.391935339245931	0.0119428204309757	5
MRE11A|MRE11	0.000408822453422601	0.387979386943038	0.00203275608785127	5
LCK|LCK	0.018203480154515	0.380462281082278	0.037888638926258	5
ACVRL1|ACVRL1	0.00251068999490572	0.350374077641049	0.00850352631730865	5
WWTR1|TAZ	0.000738780549163827	0.344514262446655	0.00331243529574806	5
CHEK2|CHK2_PT68	0.000827266950350678	0.341069557189873	0.00361172644177491	5
CDKN1B|P27_PT198	0.00508517772040334	0.339738522573237	0.0149220788844623	5
RAB11A RAB11B|RAB11	0.0051798018514361	0.33879885473689	0.0149545892162429	5
BID|BID	0.00452764113724621	0.33773703378481	0.0135074627261179	5
ARAF|A-RAF_PS299	0.00425865014923869	0.334132629036166	0.0129203114697242	5
MET|C-MET_PY1235	0.00119772863214193	0.29843774576311	0.00466072663376968	5
BECN1|BECLIN	0.0148900084164479	0.296126880943942	0.0317298988874306	5
PEA15|PEA15_PS116	0.00809501883450943	0.294885306293852	0.0204085686109463	5
TP53|P53	0.0384250595614668	0.292532453709765	0.0701845475663526	5
CDC2|CDK1	0.00386974069830499	0.292122542662749	0.0119428204309757	5
RPS6KB1|P70S6K_PT389	0.00986362938300791	0.285535441412297	0.0232314428889265	5
YWHAB|14-3-3_BETA	0.00386880866600445	0.276320796387884	0.0119428204309757	5
MAPK8|JNK_PT183_PT185	0.0140089105454152	0.275400513556962	0.0305804266784064	5
JUN|C-JUN_PS73	0.0205440124693146	0.268740539867993	0.0408597581334146	5
CCND1|CYCLIN_D1	0.00573224430402825	0.259059670475588	0.0162868528638263	5
YBX1|YB-1_PS102	0.00745725102600659	0.257705648029837	0.0196301166713997	5
RAF1|C-RAF_PS338	0.000238761732590224	0.244389231350814	0.00133557344167657	5
EGFR|EGFR_PY1173	0.00665911159435192	0.240989689432188	0.0180603178089241	5
ERRFI1|MIG-6	0.0214531574293044	0.235912556961121	0.04219906791039	5
ERBB3|HER3_PY1298	0.00139850911949179	0.233939154162749	0.00521527359143813	5
BCL2L1|BCL-XL	0.0382669261692488	0.225857665624774	0.0701845475663526	5
CDKN1B|P27	0.0184623917695876	0.223216455415009	0.0379858405374274	5
PGR|PR	0.00928964839785599	0.210748771262206	0.0221712941762163	5
ESR1|ER-ALPHA	0.0491948386372069	0.207405612803798	0.0846718857313465	5
CDH3|P-CADHERIN	0.00104522849722812	0.202909946303797	0.0042295609547817	5
CDKN1B|P27_PT157	0.00167865712631909	0.199710402033454	0.00613223725736974	5
ANXA7 |ANNEXIN_VII	0.0198096931436053	0.196399530055154	0.0398419671090489	5
RICTOR|RICTOR_PT1135	0.00865528984805605	0.181860232857143	0.0211268811531646	5
NRAS|N-RAS	0.00767341353751295	0.181839777260398	0.0199063916407945	5
MS4A1|CD20	0.00873401790689488	0.181717809444846	0.0211268811531646	5
FOXO3|FOX03A	0.0466847520677361	0.117838202766727	0.0811317535934443	5
CHEK1|CHK1_PS345	0.0339208272842468	-0.180436456409584	0.0639139798303177	5
BIRC2 |CIAP	0.0352425107930393	-0.205924386971971	0.0657125982495212	5
SMAD1|SMAD1	6.66758817503437e-05	-0.288126649378843	0.000539244005787587	5
RPTOR|RAPTOR	0.0390227037828234	-0.303058136181736	0.0704650361191993	5
PIK3CA |PI3K-P110-ALPHA	0.00131983040761045	-0.323830051691682	0.00502658814813342	5
RAD50|RAD50	0.0124191949425634	-0.335856520367089	0.0277879486839856	5
MAPK1|ERK2	0.0143997311220169	-0.370351754754069	0.0310548418173618	5
GSK3A GSK3B|GSK3-ALPHA-BETA	0.0104428281582012	-0.402766526810127	0.024276184939195	5
RAB25|RAB25	0.00839435230783013	-0.404612099199819	0.0208692925430777	5
DVL3|DVL3	0.000308690975865752	-0.414777182526221	0.00162516719646969	5
PDK1|PDK1_PS241	0.0285742375620323	-0.435860768589512	0.0544126438681253	5
EEF2|EEF2	0.024583933759279	-0.441215208442134	0.0473174639022682	5
SRC|SRC	0.0113581325712723	-0.450037162830018	0.0257355155728828	5
PRKAA1|AMPK_ALPHA	0.00195896635625015	-0.453323358401447	0.00701309955537554	5
RPS6|S6	0.0244308899316398	-0.477451067647378	0.0473174639022682	5
EEF2K|EEF2K	0.0186755520221166	-0.52011619409132	0.0379877705904417	5
NFKB1|NF-KB-P65_PS536	0.00305150284745406	-0.538827310771248	0.0101151668461903	5
MAPK9|JNK2	4.69877674037879e-06	-0.539671862626582	7.98905310196366e-05	5
PRKCA |PKC-ALPHA_PS657	1.24980528290338e-05	-0.590372974076854	0.000158150177866848	5
GAPDH|GAPDH	0.0393659419660331	-0.595690696594033	0.0704650361191993	5
PDCD4|PDCD4	0.000710278882313102	-0.620788350788427	0.00331243529574806	5
RPS6KB1|P70S6K	0.000170340641892534	-0.671114425330018	0.00105141292754357	5
FRAP1|MTOR	0.000119584525981394	-0.752065045063291	0.000792801116691464	5
TSC1|TSC1	2.85172530045267e-05	-0.816749001464738	0.000283588238211682	5
EIF4G1|EIF4G	0.000230270700821869	-0.819229510110307	0.00133557344167657	5
GATA3|GATA3	0.00241497789195343	-0.820908660345389	0.00847609887567968	5
CDH1|E-CADHERIN	0.0412823934527863	-0.868399966235985	0.0731638458222648	5
ACACA|ACC1	0.00251780388166122	-0.872656321464738	0.00850352631730865	5
PKC|PKC-PAN_BETAII_PS660	0.000234008755329107	-0.877325749413201	0.00133557344167657	5
PRKCA |PKC-ALPHA	4.84912771723153e-06	-0.890899877727848	7.98905310196366e-05	5
RBM15|RBM15	0.000111348640020788	-0.967356880443942	0.000766592560143117	5
PTEN|PTEN	2.33889161519979e-08	-0.971640204286618	1.04665399780191e-06	5
FASN|FASN	0.00591424120202712	-0.990876437017179	0.0165413933619196	5
ACACA ACACB|ACC_PS79	0.000167248818529421	-0.998813477811935	0.00105141292754357	5
BAP1|BAP1-C-4	2.15988796838784e-05	-1.01997392722694	0.000227423497847896	5
TSC2|TUBERIN	4.26076733481742e-05	-1.06815337811754	0.000381338676466159	5
ATM|ATM	7.68141739677268e-06	-1.09076879548282	0.000114581142835192	5
TP53BP1|53BP1	9.56591995726988e-07	-1.10080395394756	2.14037459043914e-05	5
AKT1 AKT2 AKT3|AKT	8.75627933097924e-06	-1.11922092969168	0.000120567230788099	5
INPP4B|INPP4B	9.47072982945027e-09	-1.14369568154882	5.65086879823866e-07	5
PRKAA1|AMPK_PT172	0.000642650764519653	-1.15467577346655	0.00310904018510859	5
XRCC5|KU80	1.70119769010785e-05	-1.17132109267902	0.000190321491580816	5
KDR|VEGFR2	0.000104898996985495	-1.25420728421881	0.000751076818416144	5
BRAF|RAF-B	3.23350146384556e-08	-1.49573581031013	1.15759352405671e-06	5
ERBB2|HER2	3.46596043540536e-15	-1.53823817142948	6.20406917937559e-13	5
STAT5A|STAT5-ALPHA	8.39263712911815e-11	-1.59776175957143	7.51141023056074e-09	5
CTNNB1|BETA-CATENIN	4.17688583861256e-05	-1.64598387521157	0.000381338676466159	5
RICTOR|RICTOR	9.76931428200032e-08	-1.65694180020253	2.9145120941301e-06	5
VHL|VHL	1.48634148899708e-07	-2.34099203115732	3.80078752186396e-06	5