Hybridization REF	p	difference	q	subclass
Composite Element REF	p	difference	q	subclass
ERBB2|HER2	9.6204187636708e-16	1.67974738888756	8.61027479348537e-14	1
VHL|VHL	2.93884932819581e-07	1.39796552884552	2.19189179061271e-06	1
INPP4B|INPP4B	2.16816094786936e-13	1.37995678928366	9.70252024171539e-12	1
CDH1|E-CADHERIN	6.73748300287415e-10	1.17936270063534	1.27623069601482e-08	1
FASN|FASN	2.54025453507205e-09	1.09767368219925	3.03137041185265e-08	1
GATA3|GATA3	8.41630337119929e-08	1.06674767482126	7.17389668306987e-07	1
CTNNB1|BETA-CATENIN	7.85329889763548e-08	0.900964700758373	7.02870251338375e-07	1
RB1|RB_PS807_S811	1.45393451637737e-09	0.873055385502051	2.16878565359624e-08	1
ACACA ACACB|ACC_PS79	1.5619565083493e-12	0.85203433875393	5.59180429989049e-11	1
SRC|SRC_PY527	5.60477953323954e-06	0.836471978298018	2.38870365821399e-05	1
PDCD4|PDCD4	4.16180819867315e-07	0.745150395743336	2.86524487524036e-06	1
SRC|SRC	4.71417661701456e-08	0.701805401263158	4.4412506023453e-07	1
RBM15|RBM15	5.74934128266931e-07	0.699347539534176	3.80820338170835e-06	1
BRAF|RAF-B	1.03828481176657e-06	0.671847162804511	5.63190852443079e-06	1
ACACA|ACC1	4.84467469471858e-05	0.568694151368421	0.000173439354070925	1
CLDN7|CLAUDIN-7	0.00287204010835603	0.537962638257006	0.00704239971774972	1
PTEN|PTEN	3.33883153176959e-07	0.530534348556049	2.39060337674703e-06	1
ERBB2|HER2_PY1248	0.000385274282227356	0.521899515321941	0.00118903614687408	1
NFKB1|NF-KB-P65_PS536	0.000263494470571906	0.520034584866029	0.000857554731497658	1
BAP1|BAP1-C-4	1.42492381324386e-08	0.514532114063226	1.50036095629795e-07	1
ERBB3|HER3	8.23038580365346e-05	0.48561231680998	0.000288870403696857	1
TP53BP1|53BP1	2.85275056430483e-06	0.478385238515038	1.38011446219072e-05	1
PKC|PKC-PAN_BETAII_PS660	1.54666380829561e-05	0.463307778012645	6.15228492633143e-05	1
XRCC5|KU80	1.1395898370049e-06	0.462666089460355	5.99960531834933e-06	1
RAB25|RAB25	5.44376658434553e-06	0.452129779518455	2.37666882584841e-05	1
STAT5A|STAT5-ALPHA	0.00104913091784815	0.408011481783664	0.00284537021658816	1
RPS6|S6	3.70727098178699e-05	0.404412331485304	0.000135428878722423	1
EIF4EBP1|4E-BP1_PT37_T46	0.0058747281873224	0.402079336211893	0.0126695945244664	1
RPS6|S6_PS240_S244	0.00359351743425619	0.398736093978469	0.00824666180425459	1
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	0.00236427468605859	0.364463620697881	0.0059606361803449	1
MAPK14|P38_PT180_Y182	0.0124326252746245	0.358681085890977	0.0249384065643747	1
RPS6|S6_PS235_S236	0.00743114750620321	0.352457510725906	0.0156491223954162	1
GSK3A GSK3B|GSK3_PS9	0.0023100282624886	0.344149594935065	0.00590707227122085	1
CHEK1|CHK1_PS345	6.68071322331895e-07	0.319487787408066	4.12361264473825e-06	1
CCNE1|CYCLIN_E1	0.02414462553045	0.312085229278537	0.0436554340399045	1
RPS6KB1|P70S6K	1.30978478126805e-05	0.30563960836432	5.32844263288593e-05	1
EEF2K|EEF2K	0.00675572492696681	0.30127940285851	0.0143961281181793	1
TSC2|TUBERIN	0.00585125867508575	0.288279522503076	0.0126695945244664	1
BAD|BAD_PS112	3.97502029354172e-06	0.286459697762133	1.82443239113838e-05	1
EIF4G1|EIF4G	0.00187131965465087	0.274002161326384	0.00492597379680155	1
CHEK2|CHK2	0.000870542944318068	0.269066241152768	0.0024347997973896	1
SMAD3|SMAD3	0.000111407882403366	0.248131334494873	0.000376264357550991	1
AKT1S1|PRAS40_PT246	1.73348918690918e-05	0.222228853723513	6.7455340099292e-05	1
FRAP1|MTOR	0.000423855130829861	0.203263024942926	0.00124377161341877	1
BAK1|BAK	0.00556779885389625	0.203158762447027	0.0123041480845362	1
IRS1|IRS1	0.0370938844427721	0.197472124384826	0.0614796788449649	1
PRKAA1|AMPK_ALPHA	0.00273759133604298	0.17630388947095	0.00680595623821796	1
MYH9|MYOSIN-IIA_PS1943	0.0125388636357191	0.173520793033493	0.0249384065643747	1
CCNE2|CYCLIN_E2	0.0212696094355523	0.163470664133288	0.0393331473785371	1
ESR1|ER-ALPHA_PS118	0.000402102588364434	0.147773448354409	0.00119960605528723	1
SCD1|SCD1	0.0423310888776195	0.147686828182843	0.0688842264463081	1
XRCC1|XRCC1	0.0304460588274472	0.122266921090226	0.0531122720975096	1
RPS6KA1|P90RSK	0.0393400843186774	0.122156520923787	0.064604358651773	1
SFRS1|SF2	0.0305618102013603	0.102687585045454	0.0531122720975096	1
NRAS|N-RAS	0.0323104833235931	-0.0686493679070403	0.0550816810945063	1
RAF1|C-RAF_PS338	0.0327204125595684	-0.0878097851657554	0.055254281586441	1
EGFR|EGFR_PY1173	0.00852624695684415	-0.0907342693075872	0.0176884278017904	1
CDKN1B|P27_PT198	0.0155895610566784	-0.0919672128386876	0.0303318633602765	1
FOXO3|FOX03A	0.0213146105906039	-0.0980052602255639	0.0393331473785371	1
CDKN1B|P27_PT157	1.06244309604618e-05	-0.100128861315789	4.42272823702945e-05	1
SMAD4|SMAD4	0.0134864842362432	-0.100662259173274	0.0265283591020608	1
MET|C-MET_PY1235	0.000357215434104996	-0.103832658682502	0.0011217818018385	1
PGR|PR	0.00354699097781569	-0.104053378514696	0.00824560240297414	1
PDK1|PDK1	0.00206457448681883	-0.114579022739918	0.00535592511797928	1
CDKN1B|P27	0.028214398111786	-0.114646259326726	0.0500037352674227	1
ANXA7 |ANNEXIN_VII	0.00458506453010668	-0.115507091257348	0.0103889436821405	1
RPS6KA1|P90RSK_PT359_S363	0.0168266855744518	-0.11664777628674	0.0323868464282459	1
YWHAB|14-3-3_BETA	0.000492764425824296	-0.124143984607655	0.00142265858423466	1
MAPK14|P38_MAPK	0.0250085318665519	-0.131952454620643	0.0447652720411279	1
MAPK8|JNK_PT183_PT185	0.031523925011224	-0.141647354651059	0.0542575247789336	1
NRG1|HEREGULIN	0.0220372902184894	-0.142618893601846	0.0402517851949959	1
C12ORF5|TIGAR	0.00307104424901541	-0.152633804806562	0.00742860703478052	1
EIF4EBP1|4E-BP1_PS65	0.00466720325721605	-0.157213371862611	0.0104428672880209	1
CDH3|P-CADHERIN	8.5999746175479e-05	-0.161468387992481	0.00029603758779636	1
BID|BID	0.000194131713955803	-0.163809334849282	0.000643510681446088	1
CCND1|CYCLIN_D1	3.69959607960539e-05	-0.166070864997608	0.000135428878722423	1
PARK7|DJ-1	0.00159165052919618	-0.174023825191046	0.00425232007053905	1
STAT3|STAT3_PY705	0.00859716881986463	-0.199397305041695	0.0176884278017904	1
PIK3R1|PI3K-P85	0.000993188398416037	-0.199591633322966	0.00273508805102263	1
ESR1|ER-ALPHA	0.0111311848748216	-0.200445476060834	0.0226418419612848	1
PRKCA |PKC-ALPHA_PS657	0.045620599442762	-0.209091770388585	0.0735683540563459	1
EIF4EBP1|4E-BP1	0.0335610597790642	-0.209341359265892	0.0561442028079672	1
BAX|BAX	0.000867789879967192	-0.213913729939166	0.0024347997973896	1
PECAM1|CD31	0.000294772556830968	-0.214366012522215	0.000942219422727558	1
MRE11A|MRE11	1.83856811917837e-09	-0.2348532794419	2.44093488884664e-08	1
YBX1|YB-1	9.12364707286261e-07	-0.237779093449761	5.10354008138252e-06	1
CDC2|CDK1	2.24183814452746e-05	-0.245462257998975	8.53806442277479e-05	1
BCL2L11|BIM	0.00314223774427803	-0.262661019355092	0.00749947408301023	1
EGFR|EGFR	0.019080863287127	-0.284294053327068	0.0362406122273313	1
STK11|LKB1	1.16654694559494e-11	-0.298843769173616	2.98302718944992e-10	1
YAP1|YAP	8.33088508069706e-07	-0.304838874414901	4.97076143148258e-06	1
IGFBP2|IGFBP2	0.0192338444781926	-0.313924497549214	0.0362406122273313	1
BCL2|BCL-2	2.17415319598198e-07	-0.332595216652427	1.76897010036716e-06	1
CDH2|N-CADHERIN	8.58479061677685e-09	-0.3398380690311	9.6042345025191e-08	1
STMN1|STATHMIN	7.12978042466381e-10	-0.342456309797334	1.27623069601482e-08	1
PEA15|PEA15	2.59894828434226e-07	-0.370321573819207	2.02265975172724e-06	1
CHEK1|CHK1	3.86196798074549e-08	-0.37437575724607	3.84051260307468e-07	1
YAP1|YAP_PS127	0.00351140949098377	-0.379544343122351	0.00824560240297414	1
LCK|LCK	2.36583955989401e-06	-0.397335389338346	1.17634800339174e-05	1
WWTR1|TAZ	3.83378789083699e-15	-0.397998089996241	2.28749344153274e-13	1
ACVRL1|ACVRL1	6.82759671891924e-16	-0.439960287472317	8.61027479348537e-14	1
MYC|C-MYC	4.26953794120083e-06	-0.444754429229323	1.91061822868737e-05	1
COL6A1|COLLAGEN_VI	1.269734916043e-09	-0.616325310252563	2.0662049997427e-08	1
CASP7|CASPASE-7_CLEAVEDD198	0.000398860938815618	-0.633253100751538	0.00119960605528723	1
TGM2|TRANSGLUTAMINASE	1.33534536257105e-10	-0.706832559036569	2.98783524875272e-09	1
HSPA1A|HSP70	1.90911108624877e-09	-0.833003992769993	2.44093488884664e-08	1
SERPINE1|PAI-1	9.05246309370281e-07	-0.97339240402324	5.10354008138252e-06	1
CAV1|CAVEOLIN-1	5.95696618367786e-07	-0.974195652705058	3.80820338170835e-06	1
RICTOR|RICTOR	3.62833945920286e-06	-0.998284536894054	1.70913885051924e-05	1
FN1|FIBRONECTIN	3.07005878975221e-12	-1.16639869445044	9.15900872276076e-11	1
MYH11|MYH11	1.82202593410117e-06	-1.36104091448257	9.3183612058317e-06	1
MYH11|MYH11	2.20224525520017e-18	2.52777438487857	3.9420190068083e-16	2
RICTOR|RICTOR	3.81547744180536e-13	2.2604342800125	2.27656820694386e-11	2
CAV1|CAVEOLIN-1	2.7534931795818e-07	1.02197607732143	3.28583519430095e-06	2
TGM2|TRANSGLUTAMINASE	5.63215030872637e-10	0.821409148125	1.44022129323146e-08	2
YAP1|YAP_PS127	4.76400926278516e-07	0.716331414230357	4.73754254465858e-06	2
KDR|VEGFR2	3.45974877278133e-09	0.709729069646428	6.19295030327858e-08	2
PRKCA |PKC-ALPHA_PS657	8.7358481735374e-10	0.6935054806375	1.95464602882899e-08	2
PRKCA |PKC-ALPHA	3.07669702862916e-07	0.620536601946429	3.44205480077887e-06	2
COL6A1|COLLAGEN_VI	9.48879519522365e-06	0.576168068826786	6.06605121408941e-05	2
HSPA1A|HSP70	0.00109041542161047	0.538933597871428	0.00372039245799228	2
FN1|FIBRONECTIN	0.000532891204046492	0.498878416457143	0.00205044292799189	2
KIT|C-KIT	8.83992100978611e-06	0.482290016425	5.86054022500635e-05	2
PEA15|PEA15	1.68298901308705e-09	0.428947162991071	3.34727814825091e-08	2
ACVRL1|ACVRL1	1.18430517807691e-08	0.407653612732143	1.92718751705243e-07	2
ATM|ATM	0.0034839642470234	0.382111069689286	0.00989888254312998	2
BCL2|BCL-2	3.00036592070421e-06	0.367372575046429	2.3350673904611e-05	2
TSC1|TSC1	1.01720689109567e-06	0.358315397910714	9.5831596582171e-06	2
PRKAA1|AMPK_PT172	0.00951373467215436	0.325067674683929	0.0233281987166525	2
STAT3|STAT3_PY705	7.84705100380903e-05	0.320156708328571	0.000379627602616707	2
LCK|LCK	0.00114418617869084	0.293604820094643	0.00379276529603075	2
AKT1 AKT2 AKT3|AKT	0.000643118812258152	0.290699045551786	0.00230236534788418	2
PIK3R1|PI3K-P85	2.32996379313097e-05	0.272765584542857	0.000139021172990148	2
PARK7|DJ-1	2.36269377584365e-07	0.271999919135714	3.02087275625724e-06	2
MYC|C-MYC	0.00471262161433309	0.271084954575	0.0127812010449337	2
AKT1 AKT2 AKT3|AKT_PT308	0.0238919952783153	0.253682870867857	0.0480524399417802	2
ESR1|ER-ALPHA	0.00546043585809155	0.212979603396429	0.0141654785304114	2
CDC2|CDK1	0.00110156871661224	0.194877047069643	0.00372039245799228	2
MAPK8|JNK_PT183_PT185	0.0131911477613884	0.194721354930357	0.0302719929395965	2
YAP1|YAP	0.0104234759106222	0.19436324215	0.024877362506685	2
WWTR1|TAZ	0.000278060623350286	0.194352880878571	0.00115750817627212	2
GAB2|GAB2	0.0365304125441889	0.191044817975	0.0695632323979767	2
CDKN1B|P27	0.000519806100308847	0.189522652939286	0.00205044292799189	2
RPTOR|RAPTOR	0.00387351994690006	0.173445736842857	0.0108337511014861	2
MAPK14|P38_MAPK	0.0029471926384674	0.161192941041071	0.0085088303594462	2
CDH2|N-CADHERIN	0.0224704783231485	0.155785774441071	0.0460067940206118	2
FRAP1|MTOR_PS2448	0.000679822991181304	0.141666013189286	0.00238604540042066	2
STK11|LKB1	0.00204779444781516	0.140230440333929	0.00610925343598189	2
MAPK9|JNK2	0.0296408144407528	0.138121661117857	0.0576707150532038	2
PRKCD|PKC-DELTA_PS664	0.00483671039927904	0.120459591069643	0.0129219576338947	2
MRE11A|MRE11	0.00806719806283066	0.115443644217857	0.0200559507395373	2
CDH3|P-CADHERIN	0.00525489120246185	0.108528826989286	0.0138327283123628	2
ANXA7 |ANNEXIN_VII	0.0195994483309501	0.100377459755357	0.0422686897739767	2
PGR|PR	0.0201729235760364	0.0993640752678571	0.0429875395251252	2
YWHAB|14-3-3_BETA	0.0420534606330896	0.0804923603107142	0.0792375731928741	2
RICTOR|RICTOR_PT1135	0.0497109547815487	0.0658867580857143	0.0898814232918911	2
MS4A1|CD20	0.00200569268691899	-0.0933341751196429	0.00608506764336439	2
ERRFI1|MIG-6	0.0101615064478939	-0.0988412547535715	0.0245798601915271	2
SMAD4|SMAD4	0.0105714447762045	-0.100233648825	0.0248985344071132	2
NRG1|HEREGULIN	0.0493256008281931	-0.102476413071429	0.0898814232918911	2
NOTCH1|NOTCH1	0.0491010198420792	-0.103927639005357	0.0898814232918911	2
EGFR|EGFR_PY1173	0.00131915241637253	-0.111069858876786	0.00429324150055787	2
CHEK1|CHK1_PS345	0.01501475194093	-0.111578822519643	0.0335955074678309	2
ERBB3|HER3_PY1298	0.00029217214464502	-0.112304312232143	0.00118860940662406	2
SHC1|SHC_PY317	0.00563128113694415	-0.126842140783929	0.0143999903359	2
IRS1|IRS1	0.0242384692381084	-0.142705544325	0.0482076221513489	2
NF2|NF2	0.0209618947551397	-0.146801977819643	0.0438475657119493	2
RPS6KA1|P90RSK	0.000538384455953177	-0.157110512530357	0.00205044292799189	2
PCNA|PCNA	0.0171464050854104	-0.176107995482143	0.037891438398623	2
RAD51|RAD51	0.00019182272765885	-0.178327972514286	0.000835802878067495	2
AKT1S1|PRAS40_PT246	6.8898813960893e-05	-0.197031360021429	0.000342580213861107	2
MYH9|MYOSIN-IIA_PS1943	0.0442165946793098	-0.206526625723214	0.0824455254957964	2
EIF4EBP1|4E-BP1	0.0182900136013078	-0.223612473260714	0.0399257613979768	2
SCD1|SCD1	2.56964616182851e-06	-0.241986928610714	2.09075755894229e-05	2
BRAF|RAF-B	0.0302056264890149	-0.253062398119643	0.0581377111992867	2
TP53BP1|53BP1	0.0138280290226191	-0.255337653514286	0.0313318632284661	2
EIF4G1|EIF4G	0.0014448909045976	-0.26596885535	0.00461849057005304	2
ESR1|ER-ALPHA_PS118	2.17456206987956e-16	-0.267978494273214	1.94623305254221e-14	2
SRC|SRC	0.0107234568020073	-0.268384000225	0.0249285554228481	2
CCNE1|CYCLIN_E1	0.0226178652168371	-0.274138504410714	0.0460067940206118	2
SFRS1|SF2	1.07979044195531e-10	-0.291018101453571	3.86564978220001e-09	2
EEF2|EEF2	0.00175543605816429	-0.2916542780875	0.00547080175651059	2
RPS6KB1|P70S6K	2.27534250267567e-05	-0.296345467823214	0.000139021172990148	2
CCNE2|CYCLIN_E2	7.47387289181071e-08	-0.32299187945	1.11485270636176e-06	2
SRC|SRC_PY416	0.000111957566542038	-0.323167784810714	0.00050101011027562	2
SMAD3|SMAD3	1.64572124804744e-10	-0.331387512526786	4.90973505667486e-09	2
BAK1|BAK	5.50957382035126e-11	-0.334190363307143	2.46553428460719e-09	2
CHEK2|CHK2	5.56277585037381e-05	-0.336952459355357	0.000292863787416739	2
FOXM1|FOXM1	3.86169926615646e-07	-0.34242002565	4.06614216848239e-06	2
GATA3|GATA3	0.0293023205717304	-0.357019801048214	0.057638630575162	2
PTEN|PTEN	0.00177266202166265	-0.386893406666071	0.00547080175651059	2
ACACA|ACC1	0.00249981726159143	-0.388227788755357	0.00733552934139125	2
ACACA ACACB|ACC_PS79	0.000551349961862375	-0.410754704394643	0.00205607589944511	2
EEF2K|EEF2K	0.000101193139995664	-0.412957622266072	0.000476672948926944	2
BAP1|BAP1-C-4	6.51594221850094e-05	-0.418097043685714	0.000333243902031905	2
ERBB2|HER2_PY1248	2.96211967106609e-05	-0.424094015810714	0.000165693569100259	2
GAPDH|GAPDH	0.0210664282191488	-0.443303573485714	0.0438475657119493	2
ERBB3|HER3	0.000108526996348579	-0.454490068592857	0.000498111085805016	2
RB1|RB_PS807_S811	0.000196110172507457	-0.463814569239286	0.000835802878067495	2
ITGA2|CD49B	2.19537054105502e-06	-0.472250071383929	1.87129203261356e-05	2
CTNNB1|BETA-CATENIN	0.00677427950477434	-0.511531535339286	0.0170788173430226	2
RPS6|S6	1.2573633762383e-07	-0.545485723564286	1.73129264882043e-06	2
EGFR|EGFR_PY1068	6.68720407028279e-06	-0.584002102507143	4.60388280223315e-05	2
CCNB1|CYCLIN_B1	0.000603811941080545	-0.599752805539286	0.00220576198884526	2
ERBB2|HER2	0.00463429290488018	-0.610369017003571	0.0127621296919008	2
TRFC|TRFC	2.7233074855704e-05	-0.745812551239286	0.000157249045134549	2
FASN|FASN	6.61966768721914e-06	-0.75287665465	4.60388280223315e-05	2
RBM15|RBM15	1.87848115672498e-06	-0.817383761105357	1.68124063526886e-05	2
CLDN7|CLAUDIN-7	5.78777546264971e-06	-0.863964369235714	4.31671586589291e-05	2
CDH1|E-CADHERIN	4.61513287959699e-05	-1.10572502271429	0.000250335995590261	2
CCNB1|CYCLIN_B1	4.46774547103531e-08	0.952825931137363	3.9986321965766e-06	3
CASP7|CASPASE-7_CLEAVEDD198	0.00166638334664688	0.711226240642399	0.00852236054427976	3
RBM15|RBM15	5.51901387423014e-07	0.655112833702381	1.83357793503051e-05	3
EGFR|EGFR	0.00548300062513345	0.601825188582875	0.0200297369775283	3
GAPDH|GAPDH	0.00824061293422606	0.558883999218406	0.0258784160566046	3
EIF4G1|EIF4G	4.89542799414132e-09	0.518353222753205	8.76281610951296e-07	3
DVL3|DVL3	2.65331251552644e-05	0.504127171621337	0.000339244957342309	3
BAP1|BAP1-C-4	6.14607129060505e-07	0.488339798398352	1.83357793503051e-05	3
RPS6|S6	5.24650784535156e-06	0.481121289319139	0.000104347211590881	3
EEF2K|EEF2K	0.00229272083736809	0.441847305570971	0.0113999174969136	3
ATM|ATM	0.0126764824031325	0.439477935718865	0.0378181725026786	3
FOXM1|FOXM1	0.00164929763921385	0.434349610394689	0.00852236054427976	3
EIF4EBP1|4E-BP1	4.9084354518903e-05	0.41879601691804	0.000585739963925576	3
TRFC|TRFC	0.0381233818577413	0.384926831987179	0.0922173696288607	3
XRCC5|KU80	0.000439985284647352	0.376025854882326	0.00306628615139085	3
SYK|SYK	0.0159871841140177	0.373245138847528	0.0461565476840188	3
RPS6KB1|P70S6K	9.08147091895497e-06	0.353194624893315	0.000152283082263076	3
TSC2|TUBERIN	0.000445382346012079	0.345511028460165	0.00306628615139085	3
TP53BP1|53BP1	0.00303713170256823	0.336709366110348	0.0135911643689928	3
PTEN|PTEN	0.00573718354997323	0.332884791945971	0.0205391171089042	3
BCL2L11|BIM	0.00655437665115099	0.322293865156135	0.022562181164539	3
PCNA|PCNA	0.000156725240163655	0.314968548794872	0.00162664285109394	3
EEF2|EEF2	0.00445403777588008	0.293983621343864	0.0173320165626638	3
AKT1 AKT2 AKT3|AKT	0.00116531156432584	0.293769856303571	0.00651846156294767	3
GAB2|GAB2	0.0316552195327732	0.218025135320055	0.0786983930050889	3
FRAP1|MTOR	0.000545271596549017	0.215403943149725	0.00361494873267682	3
CCNE2|CYCLIN_E2	0.00532050675750396	0.211804007951923	0.0198410564498585	3
GSK3A GSK3B|GSK3-ALPHA-BETA	0.000231151976655116	0.209198970947344	0.00188073653733026	3
PXN|PAXILLIN	0.0248942147745307	0.2052751262587	0.0655303594800146	3
MYH9|MYOSIN-IIA_PS1943	0.0234275407471061	0.194513133625458	0.0631239516084039	3
SMAD1|SMAD1	0.00275772039663962	0.186161227228022	0.0130016473471528	3
TSC1|TSC1	0.0305686806833317	0.183134686492216	0.0770675189058644	3
NOTCH1|NOTCH1	0.0406981667850405	0.157411346108059	0.0971329580602967	3
MAPK9|JNK2	0.0429177688333195	0.156851742519689	0.10108263975216	3
PIK3CA |PI3K-P110-ALPHA	0.0209469151383394	0.145634482378663	0.058585903277543	3
BRCA2|BRCA2	0.00324281518775583	0.145259032782509	0.0138205694906737	3
PGR|PR	0.00735452047212094	-0.0854418587715201	0.0248388521605594	3
FRAP1|MTOR_PS2448	0.014977322014577	-0.114651535196886	0.0439498465673653	3
CHEK1|CHK1_PS345	0.0205154952826877	-0.123285405062729	0.0582900580254143	3
BECN1|BECLIN	0.00276012625246819	-0.125038027138736	0.0130016473471528	3
RICTOR|RICTOR_PT1135	0.0011597663724128	-0.13166276017674	0.00651846156294767	3
EIF4EBP1|4E-BP1_PS65	0.0357350759660044	-0.146570808940018	0.0876243643549971	3
AKT1S1|PRAS40_PT246	0.00820409583688177	-0.14890400933837	0.0258784160566046	3
ARAF|A-RAF_PS299	0.00115741175732122	-0.149780635296245	0.00651846156294767	3
RPS6KA1|P90RSK_PT359_S363	0.0012333343847588	-0.158345842367216	0.00668990469308561	3
PRKCD|PKC-DELTA_PS664	0.000647169929029331	-0.166055142622253	0.00413726490343751	3
TSC2|TUBERIN_PT1462	0.000117545338983341	-0.1702690925	0.00131503847987613	3
RPS6KB1|P70S6K_PT389	0.0236274008813579	-0.174946108803114	0.0631239516084039	3
CDKN1B|P27	0.00322494854779657	-0.190884306627747	0.0138205694906737	3
MAPK8|JNK_PT183_PT185	0.0122941014326689	-0.198125143663919	0.0372990534991141	3
BAD|BAD_PS112	0.00419821990575426	-0.205417754601191	0.0170791218893185	3
MAP2K1|MEK1_PS217_S221	0.000163573024132351	-0.25092478684478	0.00162664285109394	3
PKC|PKC-PAN_BETAII_PS660	0.0304170733756981	-0.264708360879121	0.0770675189058644	3
RAB11A RAB11B|RAB11	2.56087301739509e-05	-0.268653603142399	0.000339244957342309	3
RPS6|S6_PS235_S236	0.0301273945327222	-0.268662887290751	0.0770675189058644	3
COL6A1|COLLAGEN_VI	0.00817294329154437	-0.331180469771978	0.0258784160566046	3
ERBB2|HER2_PY1248	0.00440591767547445	-0.346285074005952	0.0173320165626638	3
SRC|SRC	0.000183352900911019	-0.357767115220696	0.00166852484550703	3
SRC|SRC_PY416	0.000810015680834542	-0.377357258464286	0.00499975196101321	3
AKT1 AKT2 AKT3|AKT_PT308	0.00290703095472502	-0.407609885501374	0.0133425266896353	3
NFKB1|NF-KB-P65_PS536	0.00596928100772933	-0.425930240149267	0.0209510058898735	3
YAP1|YAP_PS127	0.00788996140084987	-0.471677972535714	0.0258784160566046	3
AKT1 AKT2 AKT3|AKT_PS473	0.00517928172013155	-0.474557852808608	0.0197253495298627	3
GSK3A GSK3B|GSK3_PS9	0.000195545997009427	-0.505636096751374	0.00166852484550703	3
GATA3|GATA3	0.0224047669537644	-0.541390455459707	0.0616992813034435	3
PDCD4|PDCD4	0.000195748724891886	-0.571477476414835	0.00166852484550703	3
RB1|RB_PS807_S811	0.000303923772632521	-0.579046457718864	0.00236531979570527	3
ERBB2|HER2	0.000379734621906205	-0.593648665107601	0.00283218738838378	3
MAPK1 MAPK3|MAPK_PT202_Y204	2.23711276057321e-06	-0.651646138295788	5.72061691632292e-05	3
GSK3A GSK3B|GSK3-ALPHA-BETA_PS21_S9	1.51158805875352e-05	-0.678113111382326	0.0002254785520974	3
CAV1|CAVEOLIN-1	0.0040668269716975	-0.726026700544872	0.0169293494868338	3
MAPK14|P38_PT180_Y182	9.35817823963039e-06	-0.734945257625458	0.000152283082263076	3
EIF4EBP1|4E-BP1_PT37_T46	3.69129256229178e-06	-0.754176484533883	8.25926710812786e-05	3
INPP4B|INPP4B	6.0797477170744e-07	-1.00716596129029	1.83357793503051e-05	3
SRC|SRC_PY527	1.73635399200163e-07	-1.01135906055632	1.03602454856097e-05	3
MYH11|MYH11	0.0104728514802118	-1.06632901596062	0.0323213864647916	3
SERPINE1|PAI-1	0.000817803912511314	1.42788091676861	0.00418248286684358	4
FN1|FIBRONECTIN	0.000109488006906015	1.13761273461512	0.00122489707726104	4
CAV1|CAVEOLIN-1	0.0281688019763524	0.901836069475945	0.0614904335825254	4
CHEK1|CHK1	0.000409988621753355	0.816763497332761	0.00262726665538902	4
SRC|SRC_PY416	5.16181014372086e-05	0.729685288085911	0.000787211000880082	4
TRFC|TRFC	0.018725389410482	0.718760157242268	0.0465533986732816	4
CLDN7|CLAUDIN-7	0.0180038687199733	0.706359860137457	0.0453900352235947	4
EGFR|EGFR_PY1068	0.0333872402042005	0.699032888442153	0.0679570012711044	4
MAPK1 MAPK3|MAPK_PT202_Y204	0.00287421225421494	0.659310933684994	0.0114329776334328	4
IGFBP2|IGFBP2	0.0134442835388652	0.648715491758877	0.0381988373564583	4
HSPA1A|HSP70	0.0368654820216197	0.545884868946163	0.0699760428049417	4
ITGA2|CD49B	0.00572021471862134	0.534201761348797	0.0179634813093547	4
COL6A1|COLLAGEN_VI	0.00486958948244056	0.523135974264605	0.0164463493840917	4
BAX|BAX	0.000342528061877785	0.4585258275189	0.00235817396446629	4
PECAM1|CD31	0.000410969085759177	0.458449187116266	0.00262726665538902	4
MYC|C-MYC	0.0304966812771355	0.449453985014318	0.0642224229247912	4
STMN1|STATHMIN	0.000710141342512109	0.411208654122566	0.00385197879726265	4
CDH2|N-CADHERIN	0.00219006539792065	0.388247167797824	0.00911678386576271	4
ARAF|A-RAF_PS299	0.000193460392585959	0.378054876409507	0.00192385612627148	4
SFRS1|SF2	0.0134412253805473	0.354074818592784	0.0381988373564583	4
YWHAZ|14-3-3_ZETA	0.0115512115815649	0.351496802748568	0.035045201238985	4
RPS6KA1|P90RSK_PT359_S363	0.00116429036956937	0.323455634896907	0.0056326480041329	4
LCK|LCK	0.0104553270097569	0.30925138683047	0.0322673023232153	4
NRG1|HEREGULIN	0.0371381232763657	0.299391154004009	0.0699760428049417	4
RAB11A RAB11B|RAB11	0.00472622453716775	0.291223361895189	0.0164463493840917	4
WWTR1|TAZ	0.00209422153314915	0.279221806942153	0.00911678386576271	4
SMAD4|SMAD4	0.0358616273009884	0.273027830540664	0.0699760428049417	4
SCD1|SCD1	0.0150197988295166	0.269120779400344	0.0413622152382073	4
STK11|LKB1	0.0293711708660785	0.264334969844215	0.0625885664884292	4
EIF4EBP1|4E-BP1_PS65	0.0223692549856806	0.258723841151203	0.0526854821373267	4
CDKN1B|P27_PT198	0.0140661378145894	0.258090684252005	0.0393412292001797	4
CDC2|CDK1	0.0034617193268891	0.257965914132303	0.0134706034676771	4
MAP2K1|MEK1_PS217_S221	0.0235069703525075	0.256424629242268	0.0546460739363486	4
EGFR|EGFR_PY1173	0.000799613367269818	0.245954931435281	0.00418248286684358	4
AKT1 AKT2 AKT3|AKT_PT308	0.0394625474851001	0.2455732719874	0.0728226391735352	4
MRE11A|MRE11	0.0125739504982356	0.243912860551546	0.0368973301505602	4
YBX1|YB-1_PS102	0.0056982436096283	0.23219684169874	0.0179634813093547	4
BID|BID	0.0240176832252974	0.231790993001718	0.0551175038119004	4
MET|C-MET_PY1235	0.00428377758342405	0.222320278373425	0.0153359237486581	4
CHEK2|CHK2_PT68	0.011915423212142	0.220890783749714	0.035547679249557	4
PEA15|PEA15_PS116	0.0172530385659659	0.219678821321306	0.0449023551655089	4
BECN1|BECLIN	0.0265029833050811	0.215587611591065	0.0600510634380952	4
JUN|C-JUN_PS73	0.0164153819530814	0.213343627540092	0.0438560204418145	4
ERBB3|HER3_PY1298	0.000482582257132045	0.208426588781214	0.00287940746755454	4
ACVRL1|ACVRL1	0.0444524797583356	0.207412345421535	0.0795699387674207	4
MS4A1|CD20	0.00359313000179867	0.169308216562428	0.0136844738366375	4
SHC1|SHC_PY317	0.0360114981920307	0.168288052986254	0.0699760428049417	4
CCND1|CYCLIN_D1	0.0362219287001116	0.161709378543528	0.0699760428049417	4
CDH3|P-CADHERIN	0.00497827017092557	0.155747134398053	0.0164867060313009	4
RAF1|C-RAF_PS338	0.0416951387503359	0.124710002978236	0.076157447309287	4
CDKN1B|P27_PT157	0.036861959322396	0.115654381245705	0.0699760428049417	4
FRAP1|MTOR_PS2448	0.0427346239284046	-0.0939642776975944	0.0772676533654992	4
RAF1|C-RAF	0.0281139674333152	-0.162679943008018	0.0614904335825254	4
KIT|C-KIT	0.034473282942824	-0.191284719453035	0.0693339061434325	4
CHEK1|CHK1_PS345	0.00217591298014562	-0.202259586623139	0.00911678386576271	4
XRCC1|XRCC1	0.0173087290861459	-0.221548618599656	0.0449023551655089	4
BRCA2|BRCA2	0.00382644538691718	-0.24848578575945	0.014269452588712	4
RPTOR|RAPTOR	0.0179263483449451	-0.275919311780641	0.0453900352235947	4
SMAD1|SMAD1	0.000284750975362435	-0.276895439033791	0.00212376769124483	4
PIK3CA |PI3K-P110-ALPHA	0.000702484981532494	-0.281188462373998	0.00385197879726265	4
SRC|SRC	0.0379834099803502	-0.298192453507445	0.070823233192528	4
GSK3A GSK3B|GSK3-ALPHA-BETA	0.0221936446217139	-0.302445326716495	0.0526854821373267	4
RAB25|RAB25	0.0275977490461635	-0.303555646394044	0.0614904335825254	4
CCNE1|CYCLIN_E1	0.0334090285578614	-0.32755023927606	0.0679570012711044	4
PRKAA1|AMPK_ALPHA	0.00254090061374022	-0.359008348996563	0.010336845678625	4
PDK1|PDK1_PS241	0.0318404921238794	-0.363872970189576	0.0662726522113304	4
DVL3|DVL3	1.77820395209064e-05	-0.393417946565292	0.000543603579732755	4
EEF2K|EEF2K	0.0291292877503026	-0.395336028514318	0.0625885664884292	4
MAPK9|JNK2	0.000305785012652612	-0.397891151520046	0.0021894206905927	4
GAB2|GAB2	0.00397973381166315	-0.400776740445017	0.0145382112711776	4
RPS6|S6	0.0163890762380297	-0.404764806310997	0.0438560204418145	4
RPS6KB1|P70S6K	0.00139721788105721	-0.478757872242841	0.00658163159761159	4
GATA3|GATA3	0.0191318343005304	-0.537944730164948	0.0469123060245882	4
ACACA|ACC1	0.0219216767272084	-0.567707910991409	0.0526854821373267	4
PRKCA |PKC-ALPHA_PS657	4.77070596385783e-06	-0.573782052647194	0.000213489091882638	4
PDCD4|PDCD4	0.000445706452837052	-0.582456957342497	0.00275108465716663	4
FASN|FASN	0.0456753324557362	-0.61997827825315	0.0809493515799681	4
NFKB1|NF-KB-P65_PS536	0.000528593922433787	-0.629765497312142	0.0030522036166338	4
FRAP1|MTOR	6.18813846519811e-05	-0.632290379448454	0.000791197703764615	4
TSC1|TSC1	6.14077165229837e-05	-0.658090841644903	0.000791197703764615	4
RBM15|RBM15	0.00166219176359377	-0.680631614197022	0.0076290339918791	4
EIF4G1|EIF4G	0.00024970221226611	-0.681042936743413	0.00206517677121128	4
PTEN|PTEN	2.27701176267183e-05	-0.685029983287514	0.000543603579732755	4
PKC|PKC-PAN_BETAII_PS660	0.000911880233093116	-0.685805047694731	0.00453407115899077	4
ACACA ACACB|ACC_PS79	0.00185643112918151	-0.719673150407216	0.00830752930308726	4
PRKCA |PKC-ALPHA	3.66923904916735e-05	-0.723782973381443	0.000656793789800956	4
BAP1|BAP1-C-4	5.27739218467094e-05	-0.802625064794387	0.000787211000880082	4
PRKAA1|AMPK_PT172	0.00479539776660809	-0.810458893449599	0.0164463493840917	4
TP53BP1|53BP1	9.46571179773963e-05	-0.813392344581902	0.00112957494119693	4
TSC2|TUBERIN	0.000248210092148109	-0.816179640198167	0.00206517677121128	4
ATM|ATM	0.000239546028112348	-0.900184790171821	0.00206517677121128	4
INPP4B|INPP4B	1.56517359374934e-08	-0.944646941887743	2.80166073281132e-06	4
AKT1 AKT2 AKT3|AKT	2.73320235619821e-05	-0.945631541363688	0.000543603579732755	4
XRCC5|KU80	2.63056460365262e-05	-0.956682996339633	0.000543603579732755	4
BRAF|RAF-B	0.000263078618201933	-0.987170185202749	0.00206517677121128	4
KDR|VEGFR2	0.00015209265199637	-1.0022740301701	0.0016014461592559	4
CTNNB1|BETA-CATENIN	0.00506574766324887	-1.06373837235739	0.0164867060313009	4
ERBB2|HER2	1.91903271582149e-05	-1.09357326900344	0.000543603579732755	4
STAT5A|STAT5-ALPHA	7.73846183384474e-07	-1.33878577757216	6.92592334129104e-05	4
RICTOR|RICTOR	3.6843757739284e-06	-1.40773525008992	0.000213489091882638	4
VHL|VHL	0.000265357909150053	-1.55352206077491	0.00206517677121128	4