Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.096 0.198 0.629 120.0 -9999.0 0.0 120.0 KIRREL -0.081 0.252 -9999.0 0.0 -0.796 120.0 120.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.096 0.199 -9999.0 0.0 -0.63 120.0 120.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.07 0.15 -9999.0 0.0 -0.48 120.0 120.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.043 0.112 -9999.0 0.0 -0.359 120.0 120.0 FYN -0.065 0.144 -9999.0 0.0 -0.46 120.0 120.0 mol:Ca2+ -0.069 0.149 -9999.0 0.0 -0.476 120.0 120.0 mol:DAG -0.069 0.15 -9999.0 0.0 -0.478 120.0 120.0 NPHS2 -0.008 0.031 -9999.0 0.0 -0.29 5.0 5.0 mol:IP3 -0.069 0.15 -9999.0 0.0 -0.478 120.0 120.0 regulation of endocytosis -0.055 0.136 -9999.0 0.0 -0.428 120.0 120.0 Nephrin/NEPH1/podocin/Cholesterol -0.072 0.153 -9999.0 0.0 -0.487 121.0 121.0 establishment of cell polarity -0.096 0.198 -9999.0 0.0 -0.629 120.0 120.0 Nephrin/NEPH1/podocin/NCK1-2 -0.062 0.137 -9999.0 0.0 -0.437 120.0 120.0 Nephrin/NEPH1/beta Arrestin2 -0.056 0.138 -9999.0 0.0 -0.434 120.0 120.0 NPHS1 -0.047 0.111 -9999.0 0.0 -0.294 179.0 179.0 Nephrin/NEPH1/podocin -0.065 0.145 -9999.0 0.0 -0.462 120.0 120.0 TJP1 -0.001 0.024 -9999.0 0.0 -0.79 1.0 1.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.07 0.15 -9999.0 0.0 -0.48 120.0 120.0 CD2AP -0.0 0.009 -9999.0 0.0 -0.293 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.07 0.151 -9999.0 0.0 -0.48 120.0 120.0 GRB2 -0.0 0.009 -9999.0 0.0 -0.293 1.0 1.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.057 0.174 -9999.0 0.0 -0.497 129.0 129.0 cytoskeleton organization -0.055 0.139 -9999.0 0.0 -0.446 120.0 120.0 Nephrin/NEPH1 -0.07 0.148 -9999.0 0.0 -0.472 120.0 120.0 Nephrin/NEPH1/ZO-1 -0.076 0.164 -9999.0 0.0 -0.52 120.0 120.0