Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.04	0.221	0.426	4.0	-0.666	98.0	102.0
IHH	0.016	0.081	0.263	31.0	-0.263	1.0	32.0
SHH Np/Cholesterol/GAS1	0.0	0.076	-9999.0	0.0	-0.33	49.0	49.0
LRPAP1	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	-0.0	0.075	0.328	49.0	-9999.0	0.0	49.0
SMO/beta Arrestin2	-0.018	0.207	-9999.0	0.0	-0.615	96.0	96.0
SMO	-0.041	0.21	0.318	1.0	-0.648	96.0	97.0
AKT1	-0.003	0.13	-9999.0	0.0	-0.53	30.0	30.0
ARRB2	0.022	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.019	0.153	-9999.0	0.0	-0.569	77.0	77.0
ADRBK1	0.023	0.006	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.04	0.206	0.317	1.0	-0.635	96.0	97.0
STIL	0.007	0.172	0.298	29.0	-0.481	84.0	113.0
DHH N/PTCH2	-0.01	0.143	-9999.0	0.0	-0.441	101.0	101.0
DHH N/PTCH1	-0.027	0.205	-9999.0	0.0	-0.546	121.0	121.0
PIK3CA	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.008	0.097	0.254	2.0	-0.569	29.0	31.0
PTHLH	-0.061	0.296	0.514	2.0	-0.876	105.0	107.0
determination of left/right symmetry	-0.04	0.206	0.317	1.0	-0.635	96.0	97.0
PIK3R1	0.017	0.062	-9999.0	0.0	-0.569	12.0	12.0
skeletal system development	-0.06	0.292	0.513	2.0	-0.862	105.0	107.0
IHH N/Hhip	0.027	0.056	0.253	1.0	-0.46	2.0	3.0
DHH N/Hhip	0.022	0.077	-9999.0	0.0	-0.417	31.0	31.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.04	0.206	0.317	1.0	-0.635	96.0	97.0
pancreas development	0.023	0.031	0.254	6.0	-0.568	2.0	8.0
HHAT	0.02	0.02	-9999.0	0.0	-0.569	1.0	1.0
PI3K	0.028	0.048	-9999.0	0.0	-0.402	12.0	12.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.009	0.136	-9999.0	0.0	-0.569	60.0	60.0
somite specification	-0.04	0.206	0.317	1.0	-0.635	96.0	97.0
SHH Np/Cholesterol/PTCH1	-0.024	0.159	0.297	1.0	-0.5	87.0	88.0
SHH Np/Cholesterol/PTCH2	-0.005	0.084	-9999.0	0.0	-0.331	61.0	61.0
SHH Np/Cholesterol/Megalin	-0.06	0.148	0.276	3.0	-0.331	229.0	232.0
SHH	-0.0	0.037	0.34	7.0	-0.425	1.0	8.0
catabolic process	-0.033	0.207	0.31	2.0	-0.57	122.0	124.0
SMO/Vitamin D3	-0.009	0.196	0.353	16.0	-0.571	87.0	103.0
SHH Np/Cholesterol/Hhip	0.015	0.03	0.281	4.0	-0.335	3.0	7.0
LRP2	-0.123	0.265	0.254	26.0	-0.569	276.0	302.0
receptor-mediated endocytosis	-0.079	0.219	0.303	10.0	-0.626	98.0	108.0
SHH Np/Cholesterol/BOC	-0.004	0.084	-9999.0	0.0	-0.33	62.0	62.0
SHH Np/Cholesterol/CDO	0.012	0.042	-9999.0	0.0	-0.332	13.0	13.0
mesenchymal cell differentiation	-0.015	0.03	0.333	3.0	-0.278	4.0	7.0
mol:Vitamin D3	0.002	0.18	0.342	20.0	-0.505	86.0	106.0
IHH N/PTCH2	-0.008	0.139	-9999.0	0.0	-0.472	79.0	79.0
CDON	0.014	0.067	-9999.0	0.0	-0.569	14.0	14.0
IHH N/PTCH1	-0.024	0.213	0.349	4.0	-0.573	122.0	126.0
Megalin/LRPAP1	-0.08	0.202	-9999.0	0.0	-0.417	279.0	279.0
PTCH2	-0.02	0.155	-9999.0	0.0	-0.569	79.0	79.0
SHH Np/Cholesterol	0.01	0.013	-9999.0	0.0	-0.331	1.0	1.0
PTCH1	-0.033	0.208	0.31	2.0	-0.572	122.0	124.0
HHIP	0.023	0.031	0.254	6.0	-0.569	2.0	8.0