Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.055 0.202 0.315 1.0 -0.517 68.0 69.0 MAP3K8 0.009 0.051 -9999.0 0.0 -0.572 7.0 7.0 FOS -0.019 0.143 0.32 2.0 -0.452 50.0 52.0 PRKCA -0.002 0.086 0.234 1.0 -0.576 22.0 23.0 PTPN7 0.022 0.06 0.243 62.0 -9999.0 0.0 62.0 HRAS 0.024 0.021 0.253 8.0 -9999.0 0.0 8.0 PRKCB 0.006 0.079 0.246 19.0 -0.577 15.0 34.0 NRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.026 0.036 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.009 0.09 -9999.0 0.0 -0.811 5.0 5.0 MAP2K1 -0.012 0.12 -9999.0 0.0 -0.503 45.0 45.0 ELK1 0.007 0.029 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.012 0.099 -9999.0 0.0 -0.481 39.0 39.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.006 319.0 319.0 MAPK1 -0.008 0.122 -9999.0 0.0 -0.471 41.0 41.0 RAF1 -0.011 0.097 -9999.0 0.0 -0.476 39.0 39.0 KRAS 0.023 0.005 -9999.0 0.0 -9999.0 0.0 0.0