Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.026 0.081 0.274 23.0 -9999.0 0.0 23.0 KIRREL -0.026 0.11 -9999.0 0.0 -0.401 20.0 20.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.026 0.081 -9999.0 0.0 -0.274 23.0 23.0 PLCG1 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.016 0.057 -9999.0 0.0 -0.205 20.0 20.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.06 -9999.0 0.0 -0.204 20.0 20.0 FYN -0.011 0.061 -9999.0 0.0 -0.189 25.0 25.0 mol:Ca2+ -0.016 0.057 -9999.0 0.0 -0.203 20.0 20.0 mol:DAG -0.016 0.057 -9999.0 0.0 -0.204 20.0 20.0 NPHS2 -0.002 0.012 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.016 0.057 -9999.0 0.0 -0.204 20.0 20.0 regulation of endocytosis -0.016 0.054 -9999.0 0.0 -0.182 20.0 20.0 Nephrin/NEPH1/podocin/Cholesterol -0.018 0.058 -9999.0 0.0 -0.21 20.0 20.0 establishment of cell polarity -0.026 0.081 -9999.0 0.0 -0.274 23.0 23.0 Nephrin/NEPH1/podocin/NCK1-2 -0.014 0.051 -9999.0 0.0 -0.181 20.0 20.0 Nephrin/NEPH1/beta Arrestin2 -0.016 0.054 -9999.0 0.0 -0.184 20.0 20.0 NPHS1 -0.004 0.037 -9999.0 0.0 -0.254 5.0 5.0 Nephrin/NEPH1/podocin -0.018 0.059 -9999.0 0.0 -0.189 25.0 25.0 TJP1 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.016 0.057 -9999.0 0.0 -0.205 20.0 20.0 CD2AP 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.016 0.057 -9999.0 0.0 -0.205 20.0 20.0 GRB2 0.007 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.007 0.058 -9999.0 0.0 -0.188 22.0 22.0 cytoskeleton organization 0.001 0.062 -9999.0 0.0 -0.21 20.0 20.0 Nephrin/NEPH1 -0.017 0.055 -9999.0 0.0 -0.199 20.0 20.0 Nephrin/NEPH1/ZO-1 -0.019 0.062 -9999.0 0.0 -0.223 20.0 20.0