Stabilization and expansion of the E-cadherin adherens junction
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
adherens junction organization	0.072	0.05	0.167	2.0	-0.165	1.0	3.0
epithelial cell differentiation	0.139	0.074	0.183	178.0	-9999.0	0.0	178.0
CYFIP2	0.019	0.005	-9999.0	0.0	-9999.0	0.0	0.0
ENAH	0.029	0.072	0.22	10.0	-9999.0	0.0	10.0
EGFR	0.018	0.02	-9999.0	0.0	-0.285	1.0	1.0
EPHA2	0.02	0.003	-9999.0	0.0	-9999.0	0.0	0.0
MYO6	0.038	0.031	0.18	4.0	-9999.0	0.0	4.0
CTNNB1	0.019	0.006	-9999.0	0.0	-9999.0	0.0	0.0
ABI1/Sra1/Nap1	0.037	0.013	-9999.0	0.0	-9999.0	0.0	0.0
AQP5	0.013	0.126	0.23	7.0	-0.353	21.0	28.0
CTNND1	0.02	0.002	-9999.0	0.0	-9999.0	0.0	0.0
mol:PI-4-5-P2	0.037	0.03	0.178	4.0	-9999.0	0.0	4.0
regulation of calcium-dependent cell-cell adhesion	0.034	0.033	0.167	2.0	-9999.0	0.0	2.0
EGF	0.002	0.066	-9999.0	0.0	-0.285	12.0	12.0
NCKAP1	0.02	0.004	-9999.0	0.0	-9999.0	0.0	0.0
AQP3	0.082	0.08	0.219	21.0	-9999.0	0.0	21.0
cortical microtubule organization	0.139	0.074	0.183	178.0	-9999.0	0.0	178.0
GO:0000145	0.025	0.026	0.164	4.0	-9999.0	0.0	4.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin	0.151	0.081	0.199	178.0	-9999.0	0.0	178.0
MLLT4	0.019	0.005	-9999.0	0.0	-9999.0	0.0	0.0
ARF6/GDP	0.003	0.016	-9999.0	0.0	-9999.0	0.0	0.0
ARF6	0.02	0.003	-9999.0	0.0	-9999.0	0.0	0.0
Ephrin A1/EPHA2/NCK1/GIT1	0.036	0.024	-9999.0	0.0	-9999.0	0.0	0.0
mol:Ca2+	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
VASP	0.015	0.021	0.157	1.0	-9999.0	0.0	1.0
PVRL2	0.019	0.005	-9999.0	0.0	-9999.0	0.0	0.0
ZYX	0.037	0.031	0.18	4.0	-9999.0	0.0	4.0
ARF6/GTP	0.038	0.028	-9999.0	0.0	-9999.0	0.0	0.0
CDH1	0.26	0.1	0.301	208.0	-9999.0	0.0	208.0
EGFR/EGFR/EGF/EGF	0.085	0.069	0.215	2.0	-0.132	3.0	5.0
RhoA/GDP	0.12	0.064	-9999.0	0.0	-9999.0	0.0	0.0
actin cytoskeleton organization	0.028	0.029	0.167	4.0	-9999.0	0.0	4.0
IGF-1R heterotetramer	0.018	0.02	-9999.0	0.0	-0.285	1.0	1.0
GIT1	0.02	0.003	-9999.0	0.0	-9999.0	0.0	0.0
IGF1R	0.018	0.02	-9999.0	0.0	-0.285	1.0	1.0
IGF1	-0.075	0.142	-9999.0	0.0	-0.285	76.0	76.0
DIAPH1	-0.01	0.14	-9999.0	0.0	-0.527	9.0	9.0
Wnt receptor signaling pathway	-0.139	0.074	-9999.0	0.0	-0.183	178.0	178.0
RHOA	0.019	0.006	-9999.0	0.0	-9999.0	0.0	0.0
RhoA/GTP	0.003	0.016	-9999.0	0.0	-9999.0	0.0	0.0
CTNNA1	0.019	0.005	-9999.0	0.0	-9999.0	0.0	0.0
VCL	0.029	0.029	0.168	4.0	-9999.0	0.0	4.0
EFNA1	0.019	0.005	-9999.0	0.0	-9999.0	0.0	0.0
LPP	0.015	0.022	0.154	1.0	-9999.0	0.0	1.0
Ephrin A1/EPHA2	0.09	0.056	-9999.0	0.0	-9999.0	0.0	0.0
SEC6/SEC8	0.014	0.023	-9999.0	0.0	-9999.0	0.0	0.0
MGAT3	0.035	0.034	0.168	2.0	-9999.0	0.0	2.0
HGF/MET	0.072	0.08	0.238	1.0	-0.148	2.0	3.0
HGF	-0.015	0.099	0.301	1.0	-0.285	28.0	29.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN	0.072	0.05	0.152	5.0	-0.166	1.0	6.0
actin cable formation	0.073	0.123	0.25	59.0	-0.23	3.0	62.0
KIAA1543	0.024	0.027	0.166	4.0	-9999.0	0.0	4.0
KIFC3	0.037	0.028	0.191	2.0	-9999.0	0.0	2.0
NCK1	0.015	0.009	-9999.0	0.0	-9999.0	0.0	0.0
EXOC3	0.016	0.008	-9999.0	0.0	-9999.0	0.0	0.0
ACTN1	0.038	0.031	0.18	4.0	-9999.0	0.0	4.0
NCK1/GIT1	0.022	0.013	-9999.0	0.0	-9999.0	0.0	0.0
mol:GDP	0.139	0.074	0.183	178.0	-9999.0	0.0	178.0
EXOC4	0.019	0.004	-9999.0	0.0	-9999.0	0.0	0.0
STX4	0.037	0.028	0.191	2.0	-9999.0	0.0	2.0
PIP5K1C	0.037	0.031	0.18	4.0	-9999.0	0.0	4.0
LIMA1	0.02	0.002	-9999.0	0.0	-9999.0	0.0	0.0
ABI1	0.02	0.003	-9999.0	0.0	-9999.0	0.0	0.0
ROCK1	0.059	0.092	0.281	19.0	-9999.0	0.0	19.0
adherens junction assembly	0.009	0.085	0.248	3.0	-0.501	4.0	7.0
IGF-1R heterotetramer/IGF1	0.038	0.101	-9999.0	0.0	-0.155	8.0	8.0
nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin	0.026	0.01	-9999.0	0.0	-9999.0	0.0	0.0
MET	0.019	0.004	-9999.0	0.0	-9999.0	0.0	0.0
PLEKHA7	0.036	0.031	0.18	4.0	-9999.0	0.0	4.0
mol:GTP	0.035	0.024	-9999.0	0.0	-9999.0	0.0	0.0
establishment of epithelial cell apical/basal polarity	0.055	0.081	0.201	49.0	-9999.0	0.0	49.0
cortical actin cytoskeleton stabilization	0.072	0.05	0.167	2.0	-0.165	1.0	3.0
regulation of cell-cell adhesion	0.028	0.029	0.167	4.0	-9999.0	0.0	4.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN/cortical actin cytoskeleton	0.072	0.05	0.152	5.0	-0.166	1.0	6.0