Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.002 0.086 0.477 13.0 -9999.0 0.0 13.0 KIRREL 0.007 0.044 -9999.0 0.0 -0.438 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.002 0.086 -9999.0 0.0 -0.478 13.0 13.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.002 0.091 -9999.0 0.0 -0.435 12.0 12.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.019 0.051 -9999.0 0.0 -0.477 1.0 1.0 FYN 0.006 0.071 -9999.0 0.0 -0.389 12.0 12.0 mol:Ca2+ 0.01 0.079 -9999.0 0.0 -0.431 12.0 12.0 mol:DAG 0.01 0.079 -9999.0 0.0 -0.433 12.0 12.0 NPHS2 -0.002 0.071 -9999.0 0.0 -0.741 4.0 4.0 mol:IP3 0.01 0.079 -9999.0 0.0 -0.433 12.0 12.0 regulation of endocytosis 0.014 0.068 -9999.0 0.0 -0.361 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol 0.003 0.08 -9999.0 0.0 -0.442 12.0 12.0 establishment of cell polarity 0.002 0.086 -9999.0 0.0 -0.477 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 0.018 0.074 -9999.0 0.0 -0.396 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 0.015 0.069 -9999.0 0.0 -0.366 12.0 12.0 NPHS1 -0.005 0.105 -9999.0 0.0 -0.732 9.0 9.0 Nephrin/NEPH1/podocin 0.007 0.072 -9999.0 0.0 -0.391 12.0 12.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.011 0.08 -9999.0 0.0 -0.435 12.0 12.0 CD2AP -0.002 0.078 -9999.0 0.0 -0.435 14.0 14.0 Nephrin/NEPH1/podocin/GRB2 0.011 0.08 -9999.0 0.0 -0.435 12.0 12.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.004 0.091 -9999.0 0.0 -0.402 14.0 14.0 cytoskeleton organization 0.022 0.064 -9999.0 0.0 -0.635 1.0 1.0 Nephrin/NEPH1 0.003 0.063 -9999.0 0.0 -0.408 9.0 9.0 Nephrin/NEPH1/ZO-1 0.011 0.071 -9999.0 0.0 -0.45 9.0 9.0