Stabilization and expansion of the E-cadherin adherens junction
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
adherens junction organization	-0.003	0.101	-9999.0	0.0	-0.256	18.0	18.0
epithelial cell differentiation	0.056	0.059	-9999.0	0.0	-0.269	4.0	4.0
CYFIP2	0.021	0.078	-9999.0	0.0	-0.514	3.0	3.0
ENAH	-0.001	0.05	-9999.0	0.0	-9999.0	0.0	0.0
EGFR	0.018	0.078	-9999.0	0.0	-0.514	3.0	3.0
EPHA2	0.013	0.076	-9999.0	0.0	-0.321	7.0	7.0
MYO6	0.012	0.048	-9999.0	0.0	-0.259	4.0	4.0
CTNNB1	0.029	0.029	-9999.0	0.0	-0.321	1.0	1.0
ABI1/Sra1/Nap1	0.055	0.058	-9999.0	0.0	-0.317	3.0	3.0
AQP5	0.007	0.051	-9999.0	0.0	-9999.0	0.0	0.0
CTNND1	0.032	0.005	-9999.0	0.0	-9999.0	0.0	0.0
mol:PI-4-5-P2	0.012	0.047	-9999.0	0.0	-0.255	4.0	4.0
regulation of calcium-dependent cell-cell adhesion	0.001	0.068	-9999.0	0.0	-0.257	9.0	9.0
EGF	-0.112	0.225	-9999.0	0.0	-0.446	44.0	44.0
NCKAP1	0.03	0.029	-9999.0	0.0	-0.321	1.0	1.0
AQP3	0.01	0.052	-9999.0	0.0	-9999.0	0.0	0.0
cortical microtubule organization	0.056	0.059	-9999.0	0.0	-0.269	4.0	4.0
GO:0000145	-0.002	0.042	-9999.0	0.0	-0.244	4.0	4.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin	0.062	0.061	-9999.0	0.0	-0.272	4.0	4.0
MLLT4	0.031	0.005	-9999.0	0.0	-9999.0	0.0	0.0
ARF6/GDP	-0.007	0.056	-9999.0	0.0	-0.352	2.0	2.0
ARF6	0.029	0.009	-9999.0	0.0	-9999.0	0.0	0.0
Ephrin A1/EPHA2/NCK1/GIT1	0.06	0.058	-9999.0	0.0	-9999.0	0.0	0.0
mol:Ca2+	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
VASP	0.007	0.042	-9999.0	0.0	-9999.0	0.0	0.0
PVRL2	0.032	0.004	-9999.0	0.0	-9999.0	0.0	0.0
ZYX	0.01	0.049	-9999.0	0.0	-0.259	4.0	4.0
ARF6/GTP	0.062	0.06	-9999.0	0.0	-9999.0	0.0	0.0
CDH1	0.017	0.089	-9999.0	0.0	-0.514	4.0	4.0
EGFR/EGFR/EGF/EGF	-0.036	0.134	-9999.0	0.0	-0.262	30.0	30.0
RhoA/GDP	0.058	0.058	-9999.0	0.0	-0.256	4.0	4.0
actin cytoskeleton organization	0.005	0.045	-9999.0	0.0	-0.253	4.0	4.0
IGF-1R heterotetramer	0.03	0.008	-9999.0	0.0	-9999.0	0.0	0.0
GIT1	0.031	0.007	-9999.0	0.0	-9999.0	0.0	0.0
IGF1R	0.03	0.008	-9999.0	0.0	-9999.0	0.0	0.0
IGF1	-0.29	0.269	-9999.0	0.0	-0.514	86.0	86.0
DIAPH1	0.045	0.131	-9999.0	0.0	-0.657	3.0	3.0
Wnt receptor signaling pathway	-0.056	0.059	0.269	4.0	-9999.0	0.0	4.0
RHOA	0.032	0.004	-9999.0	0.0	-9999.0	0.0	0.0
RhoA/GTP	-0.007	0.056	-9999.0	0.0	-0.353	2.0	2.0
CTNNA1	0.032	0.004	-9999.0	0.0	-9999.0	0.0	0.0
VCL	0.005	0.046	-9999.0	0.0	-0.259	4.0	4.0
EFNA1	0.031	0.005	-9999.0	0.0	-9999.0	0.0	0.0
LPP	0.002	0.044	-9999.0	0.0	-0.248	4.0	4.0
Ephrin A1/EPHA2	0.037	0.075	-9999.0	0.0	-0.318	4.0	4.0
SEC6/SEC8	0.009	0.044	-9999.0	0.0	-9999.0	0.0	0.0
MGAT3	0.001	0.069	-9999.0	0.0	-0.26	9.0	9.0
HGF/MET	-0.043	0.105	-9999.0	0.0	-0.296	3.0	3.0
HGF	0.031	0.007	-9999.0	0.0	-9999.0	0.0	0.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN	-0.003	0.102	-9999.0	0.0	-0.258	18.0	18.0
actin cable formation	0.014	0.07	0.356	1.0	-0.308	1.0	2.0
KIAA1543	-0.002	0.043	-9999.0	0.0	-0.247	4.0	4.0
KIFC3	0.011	0.049	-9999.0	0.0	-0.259	4.0	4.0
NCK1	0.032	0.004	-9999.0	0.0	-9999.0	0.0	0.0
EXOC3	0.031	0.007	-9999.0	0.0	-9999.0	0.0	0.0
ACTN1	0.01	0.048	-9999.0	0.0	-0.259	4.0	4.0
NCK1/GIT1	0.045	0.012	-9999.0	0.0	-9999.0	0.0	0.0
mol:GDP	0.056	0.059	-9999.0	0.0	-0.269	4.0	4.0
EXOC4	0.031	0.007	-9999.0	0.0	-9999.0	0.0	0.0
STX4	0.012	0.048	-9999.0	0.0	-0.259	4.0	4.0
PIP5K1C	0.012	0.048	-9999.0	0.0	-0.259	4.0	4.0
LIMA1	-0.024	0.166	-9999.0	0.0	-0.514	15.0	15.0
ABI1	0.032	0.003	-9999.0	0.0	-9999.0	0.0	0.0
ROCK1	0.006	0.065	0.308	1.0	-0.314	2.0	3.0
adherens junction assembly	0.009	0.046	-9999.0	0.0	-9999.0	0.0	0.0
IGF-1R heterotetramer/IGF1	-0.131	0.158	-9999.0	0.0	-0.259	85.0	85.0
nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin	0.046	0.009	-9999.0	0.0	-9999.0	0.0	0.0
MET	-0.13	0.175	-9999.0	0.0	-0.322	66.0	66.0
PLEKHA7	0.012	0.048	-9999.0	0.0	-0.259	4.0	4.0
mol:GTP	0.057	0.057	-9999.0	0.0	-9999.0	0.0	0.0
establishment of epithelial cell apical/basal polarity	0.025	0.068	0.335	1.0	-9999.0	0.0	1.0
cortical actin cytoskeleton stabilization	-0.003	0.101	-9999.0	0.0	-0.256	18.0	18.0
regulation of cell-cell adhesion	0.005	0.045	-9999.0	0.0	-0.253	4.0	4.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN/cortical actin cytoskeleton	-0.003	0.102	-9999.0	0.0	-0.258	18.0	18.0