Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 50 (8%) 565 0.24019 1 0.37235 1 0.01513 1 0.74849 1 0.01456 1 0.01618 1 0.75064 1 0.51772 1 0.38449 1 0.31303 1 0.19341 1 0.59004 1 1q gain 117 (19%) 498 0.77478 1 0.55105 1 0.0051599 1 0.52759 1 0.12593 1 0.01741 1 0.91383 1 0.54804 1 0.17047 1 0.14078 1 0.5578 1 0.40763 1 2p gain 123 (20%) 492 0.02192 1 0.0053499 1 0.0017 1 0.00246 1 0.62101 1 0.56569 1 9.9999e-06 0.00935 3e-05 0.0256 0.03325 1 0.00126 0.983 0.98781 1 0.96976 1 2q gain 121 (20%) 494 0.01309 1 0.00142 1 2e-04 0.166 0.00086999 0.687 0.64779 1 0.85506 1 0.00083999 0.664 3e-05 0.0256 0.093199 1 0.0091999 1 0.93716 1 0.81275 1 3p gain 73 (12%) 542 0.01322 1 0.078609 1 9.9999e-06 0.00935 0.11768 1 0.12186 1 0.02421 1 0.73736 1 0.01321 1 0.10672 1 0.43556 1 0.10031 1 0.27199 1 3q gain 99 (16%) 516 0.034 1 0.00211 1 9.9999e-06 0.00935 0.01443 1 0.12467 1 0.01963 1 0.052079 1 0.00022 0.182 0.0427 1 0.54801 1 0.02003 1 0.051759 1 4p gain 20 (3%) 595 0.81455 1 0.56868 1 0.0068499 1 0.21009 1 0.15598 1 0.17525 1 0.01853 1 0.12272 1 0.58271 1 0.50381 1 0.6742 1 0.13444 1 4q gain 21 (3%) 594 0.22662 1 0.21569 1 0.02336 1 0.60429 1 0.11383 1 0.51555 1 0.087339 1 0.27535 1 0.33043 1 0.36561 1 0.88011 1 1 1 5p gain 105 (17%) 510 0.49626 1 0.12905 1 0.00027 0.222 0.76119 1 0.16218 1 0.1317 1 0.0055799 1 0.00013 0.109 0.75491 1 0.39303 1 0.45998 1 0.55771 1 5q gain 67 (11%) 548 0.90646 1 0.55191 1 4e-04 0.326 0.81831 1 0.65019 1 0.76655 1 0.057589 1 0.00457 1 0.54883 1 0.0018 1 0.99727 1 1 1 6p gain 124 (20%) 491 0.0143 1 0.00045 0.364 9.9999e-06 0.00935 0.28231 1 0.85366 1 0.96658 1 0.18887 1 0.01558 1 0.45773 1 0.71099 1 0.02631 1 0.03382 1 6q gain 111 (18%) 504 0.15489 1 0.00109 0.855 9.9999e-06 0.00935 0.32717 1 0.82673 1 0.73746 1 0.16328 1 0.02317 1 0.35774 1 0.89206 1 0.0092999 1 0.04695 1 7p gain 349 (57%) 266 4e-04 0.326 9.9999e-06 0.00935 9.9999e-06 0.00935 2e-05 0.0172 0.0091799 1 0.0078299 1 9.9999e-06 0.00935 9.9999e-06 0.00935 0.0057699 1 0.17799 1 0.02768 1 0.087659 1 7q gain 312 (51%) 303 0.00014 0.117 9.9999e-06 0.00935 9.9999e-06 0.00935 6.9999e-05 0.0591 0.13167 1 0.02763 1 5e-05 0.0424 9.9999e-06 0.00935 0.01335 1 0.23805 1 0.077019 1 0.43829 1 8p gain 170 (28%) 445 0.92411 1 0.53123 1 2e-05 0.0172 0.81025 1 0.23499 1 0.42569 1 0.0054499 1 0.01679 1 0.20427 1 0.26756 1 0.39401 1 0.11976 1 8q gain 315 (51%) 300 0.32933 1 0.10902 1 9.9999e-06 0.00935 0.056899 1 0.059369 1 0.077169 1 0.00045 0.364 0.00051999 0.419 0.29151 1 0.0098599 1 0.10684 1 0.04348 1 9p gain 123 (20%) 492 0.53871 1 0.5864 1 0.00241 1 0.58325 1 0.12817 1 0.25517 1 0.91533 1 0.18184 1 0.97864 1 0.92089 1 0.62857 1 0.79133 1 9q gain 102 (17%) 513 0.65632 1 0.83202 1 0.03711 1 0.95338 1 0.10242 1 0.31713 1 0.95053 1 0.58979 1 0.6423 1 0.41738 1 0.93332 1 0.83566 1 10p gain 49 (8%) 566 0.10952 1 0.11353 1 0.00378 1 0.83741 1 0.10703 1 0.04893 1 0.47303 1 0.98016 1 0.50512 1 0.30347 1 0.54288 1 0.46331 1 10q gain 29 (5%) 586 0.9106 1 0.25902 1 0.057599 1 0.14904 1 0.16729 1 0.70666 1 0.96545 1 0.85806 1 0.51905 1 0.66143 1 0.17987 1 0.95271 1 11p gain 85 (14%) 530 0.01237 1 0.0052299 1 9.9999e-06 0.00935 9.9999e-06 0.00935 0.65624 1 0.63086 1 0.00107 0.84 0.00060999 0.488 0.33173 1 0.40321 1 0.78669 1 0.97318 1 11q gain 77 (13%) 538 0.01693 1 0.00101 0.795 9.9999e-06 0.00935 9.9999e-06 0.00935 0.19365 1 0.37189 1 9.9999e-06 0.00935 9.9999e-06 0.00935 0.29912 1 0.060769 1 0.301 1 0.17961 1 12p gain 127 (21%) 488 0.35751 1 0.35926 1 0.00466 1 0.00337 1 0.46003 1 0.24198 1 0.77425 1 0.1256 1 0.41447 1 0.78423 1 0.56536 1 0.48474 1 12q gain 112 (18%) 503 0.2511 1 0.34593 1 0.00258 1 0.00149 1 0.49438 1 0.34878 1 0.539 1 0.057129 1 0.25519 1 0.52491 1 0.55236 1 0.42112 1 13q gain 368 (60%) 247 9.9999e-06 0.00935 9.9999e-06 0.00935 9.9999e-06 0.00935 9.9999e-06 0.00935 0.24042 1 0.38016 1 9.9999e-06 0.00935 9.9999e-06 0.00935 0.00053999 0.434 0.44139 1 0.01458 1 0.070009 1 14q gain 43 (7%) 572 0.73595 1 0.40339 1 0.01541 1 0.8777 1 0.78891 1 0.82767 1 0.54083 1 0.80541 1 0.8835 1 0.89023 1 0.78422 1 0.34141 1 15q gain 15 (2%) 600 0.29779 1 0.15316 1 0.062529 1 0.54227 1 0.17336 1 0.2086 1 0.92477 1 0.69435 1 1 1 0.72565 1 NA NA NA NA 16p gain 147 (24%) 468 0.0059999 1 0.00424 1 9.9999e-06 0.00935 0.0099399 1 0.14154 1 0.66154 1 0.00012 0.101 9.9999e-06 0.00935 0.49196 1 0.43469 1 0.22345 1 0.18417 1 16q gain 145 (24%) 470 0.0087699 1 0.00374 1 9.9999e-06 0.00935 0.01953 1 0.23089 1 0.4713 1 0.00026 0.214 9.9999e-06 0.00935 0.78541 1 0.47704 1 0.10743 1 0.12183 1 17p gain 38 (6%) 577 0.44097 1 0.16279 1 0.75391 1 0.89988 1 0.1989 1 1 1 0.11043 1 0.25224 1 0.16898 1 0.72247 1 0.074049 1 0.93888 1 17q gain 113 (18%) 502 0.01118 1 0.0034 1 9.9999e-06 0.00935 0.00145 1 0.27481 1 0.67157 1 3e-05 0.0256 0.00015 0.125 0.00227 1 0.04365 1 0.86566 1 0.27958 1 18p gain 33 (5%) 582 0.30761 1 0.37171 1 0.00172 1 0.00060999 0.488 0.60385 1 0.060749 1 0.0094199 1 0.00055999 0.449 0.39419 1 0.078209 1 0.75848 1 0.97675 1 18q gain 20 (3%) 595 0.04482 1 0.43652 1 0.0089799 1 0.0080699 1 0.61339 1 0.01407 1 0.0084999 1 9.9999e-06 0.00935 0.12997 1 0.02232 1 0.67117 1 0.82946 1 19p gain 104 (17%) 511 0.32734 1 0.01889 1 9.9999e-06 0.00935 0.04155 1 0.15983 1 0.77249 1 0.31724 1 0.00053999 0.434 0.04227 1 0.72932 1 0.51665 1 0.089809 1 19q gain 114 (19%) 501 0.051139 1 0.00348 1 0.00025 0.206 0.077749 1 0.03148 1 0.4929 1 0.70063 1 0.00050999 0.411 0.21606 1 1 1 0.16529 1 0.084019 1 20p gain 354 (58%) 261 4e-04 0.326 9.9999e-06 0.00935 9.9999e-06 0.00935 0.00129 1 0.02777 1 0.11574 1 0.00048 0.388 9.9999e-06 0.00935 0.35715 1 0.092119 1 0.57503 1 0.11019 1 20q gain 465 (76%) 150 9.9999e-06 0.00935 9.9999e-06 0.00935 9.9999e-06 0.00935 9.9999e-06 0.00935 0.00317 1 0.0053499 1 9.9999e-06 0.00935 9.9999e-06 0.00935 0.016 1 0.00036 0.295 0.00066999 0.535 0.01919 1 21q gain 34 (6%) 581 0.31256 1 0.26364 1 4e-04 0.326 0.7644 1 0.48625 1 0.25566 1 0.80088 1 0.33735 1 0.40681 1 0.9678 1 0.4601 1 0.74336 1 22q gain 23 (4%) 592 0.11812 1 0.13674 1 0.01006 1 0.32978 1 0.85961 1 0.69429 1 0.11557 1 0.32197 1 0.69215 1 0.91726 1 0.84182 1 1 1 xq gain 105 (17%) 510 0.1398 1 0.26858 1 0.00052999 0.426 0.11909 1 0.10993 1 0.066569 1 0.66279 1 0.95802 1 0.37665 1 0.97831 1 0.76912 1 0.9444 1 1p loss 138 (22%) 477 0.066039 1 0.03023 1 9.9999e-06 0.00935 0.00238 1 0.96798 1 0.90908 1 4e-04 0.326 0.00088999 0.702 0.34787 1 0.066879 1 0.76589 1 0.31266 1 1q loss 80 (13%) 535 0.23479 1 0.21223 1 0.00035 0.288 0.19299 1 0.86622 1 0.81264 1 4e-05 0.034 0.0072299 1 0.768 1 0.0093399 1 0.16596 1 0.15278 1 2p loss 17 (3%) 598 1 1 0.62026 1 5e-04 0.403 0.03285 1 0.34857 1 0.80933 1 0.16731 1 0.02816 1 0.093939 1 0.22955 1 NA NA NA NA 2q loss 14 (2%) 601 0.67419 1 0.24586 1 0.01471 1 0.18696 1 0.25 1 0.37073 1 0.12573 1 0.01177 1 0.089659 1 0.02215 1 NA NA NA NA 3p loss 70 (11%) 545 0.35943 1 0.8357 1 0.48931 1 0.46219 1 0.53563 1 0.62606 1 0.53456 1 0.66541 1 0.77025 1 0.39864 1 0.38448 1 0.35067 1 3q loss 45 (7%) 570 0.24732 1 0.24805 1 0.90334 1 0.53554 1 0.32322 1 0.95787 1 0.59919 1 0.12878 1 0.57568 1 0.33853 1 0.65421 1 0.78775 1 4p loss 197 (32%) 418 0.0287 1 0.01633 1 9.9999e-06 0.00935 0.00131 1 0.47574 1 0.29598 1 0.00019 0.158 0.00014 0.117 0.082469 1 0.46512 1 0.20101 1 0.91939 1 4q loss 191 (31%) 424 0.04142 1 0.075269 1 9.9999e-06 0.00935 3e-05 0.0256 0.75986 1 0.59176 1 0.00123 0.961 5e-05 0.0424 0.10408 1 0.13662 1 0.03839 1 0.5021 1 5p loss 85 (14%) 530 0.37733 1 0.69814 1 0.00036 0.295 0.04531 1 0.74638 1 0.64272 1 0.62862 1 0.16615 1 0.95628 1 0.26304 1 0.45301 1 0.94357 1 5q loss 119 (19%) 496 0.01221 1 0.03731 1 9.9999e-06 0.00935 0.02736 1 0.20455 1 0.085269 1 0.01133 1 0.03278 1 0.47908 1 0.62907 1 0.69093 1 0.67422 1 6p loss 46 (7%) 569 0.56128 1 0.02255 1 0.51826 1 0.87075 1 0.069459 1 0.077509 1 0.65851 1 0.25339 1 0.4579 1 0.93593 1 0.53345 1 0.77668 1 6q loss 69 (11%) 546 0.43791 1 0.31038 1 0.31817 1 0.69117 1 0.23075 1 0.15639 1 0.13826 1 0.15797 1 0.51524 1 0.51593 1 0.13421 1 0.53215 1 7p loss 3 (0%) 612 NA NA NA NA 0.61525 1 NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA 7q loss 5 (1%) 610 NA NA NA NA 0.62509 1 1 1 1 1 0.74228 1 0.57591 1 0.7373 1 1 1 0.22357 1 NA NA NA NA 8p loss 218 (35%) 397 0.0089899 1 0.0056199 1 9.9999e-06 0.00935 5.9999e-05 0.0507 0.44387 1 0.02679 1 0.00072999 0.58 9.9999e-06 0.00935 0.665 1 0.24012 1 0.00251 1 0.46988 1 8q loss 37 (6%) 578 0.91057 1 0.78104 1 0.00439 1 0.7163 1 0.95665 1 0.22603 1 0.46477 1 0.75252 1 0.27174 1 0.58053 1 0.051469 1 0.03948 1 9p loss 77 (13%) 538 0.4919 1 0.20183 1 0.00088999 0.702 0.0085999 1 0.84423 1 0.47347 1 0.00018 0.15 0.0075299 1 0.20765 1 0.11422 1 0.67663 1 0.71131 1 9q loss 77 (13%) 538 0.04771 1 0.01429 1 0.00075999 0.603 0.00162 1 0.85808 1 0.30356 1 9.9999e-05 0.0841 0.00111 0.869 0.39155 1 0.01743 1 0.80125 1 0.32465 1 10p loss 102 (17%) 513 0.01038 1 0.18682 1 9.9999e-06 0.00935 0.01086 1 0.01766 1 0.4113 1 0.00102 0.802 8.9999e-05 0.0758 0.20947 1 0.36088 1 0.054839 1 0.25091 1 10q loss 111 (18%) 504 0.02302 1 0.24805 1 9.9999e-06 0.00935 0.0094999 1 0.01198 1 0.3352 1 0.00078999 0.626 9.9999e-06 0.00935 0.61515 1 0.41571 1 0.04788 1 0.26803 1 11p loss 75 (12%) 540 0.95356 1 1 1 0.02126 1 0.19114 1 0.49975 1 0.60673 1 0.71093 1 0.21343 1 0.91161 1 0.23629 1 0.65871 1 0.85185 1 11q loss 93 (15%) 522 0.84579 1 0.6837 1 0.02697 1 0.04705 1 0.95671 1 0.70025 1 0.95816 1 0.48738 1 0.80492 1 0.41736 1 0.27698 1 0.28494 1 12p loss 71 (12%) 544 0.066499 1 0.0145 1 9.9999e-06 0.00935 0.059149 1 0.87511 1 0.58496 1 0.02622 1 0.00067999 0.542 0.81807 1 0.82159 1 0.28307 1 0.26215 1 12q loss 70 (11%) 545 0.12566 1 0.02593 1 9.9999e-06 0.00935 0.068819 1 0.64355 1 0.97389 1 0.00396 1 0.00038 0.311 0.26191 1 0.88512 1 0.42715 1 0.36575 1 13q loss 20 (3%) 595 0.29796 1 0.01647 1 0.01431 1 0.34747 1 0.29847 1 0.0069199 1 0.45051 1 0.2581 1 0.73448 1 0.78889 1 0.01408 1 0.41418 1 14q loss 207 (34%) 408 0.00027 0.222 6.9999e-05 0.0591 9.9999e-06 0.00935 9.9999e-06 0.00935 0.00257 1 0.18223 1 9.9999e-06 0.00935 9.9999e-06 0.00935 0.13448 1 0.11945 1 0.03656 1 0.04508 1 15q loss 229 (37%) 386 9.9999e-05 0.0841 0.00163 1 9.9999e-06 0.00935 0.00041 0.333 0.23291 1 0.78284 1 4e-05 0.034 9.9999e-06 0.00935 0.82055 1 0.68566 1 0.078589 1 0.20846 1 16p loss 41 (7%) 574 0.072599 1 0.37403 1 0.32855 1 0.94084 1 0.34259 1 0.23809 1 0.4624 1 0.54929 1 0.83499 1 0.23826 1 0.30334 1 0.95281 1 16q loss 44 (7%) 571 0.02532 1 0.585 1 0.0079599 1 0.90895 1 0.23903 1 0.23735 1 0.61378 1 0.71176 1 0.57381 1 0.55796 1 0.27753 1 0.87013 1 17p loss 341 (55%) 274 2e-05 0.0172 4e-05 0.034 9.9999e-06 0.00935 9.9999e-06 0.00935 0.12269 1 0.0084099 1 9.9999e-06 0.00935 9.9999e-06 0.00935 0.0352 1 0.0233 1 0.02812 1 0.37999 1 17q loss 94 (15%) 521 0.97895 1 0.61866 1 0.00068999 0.549 0.52912 1 0.94687 1 0.03696 1 0.86188 1 0.02548 1 0.77061 1 0.44254 1 0.71536 1 0.96155 1 18p loss 379 (62%) 236 9.9999e-06 0.00935 9.9999e-06 0.00935 9.9999e-06 0.00935 9.9999e-06 0.00935 0.03003 1 0.04799 1 9.9999e-06 0.00935 9.9999e-06 0.00935 0.0073999 1 0.0092399 1 0.00021 0.174 0.00115 0.899 18q loss 408 (66%) 207 9.9999e-06 0.00935 9.9999e-06 0.00935 9.9999e-06 0.00935 9.9999e-06 0.00935 0.050699 1 0.10315 1 9.9999e-06 0.00935 9.9999e-06 0.00935 0.00073999 0.588 0.00462 1 0.00015 0.125 0.00035 0.288 19p loss 64 (10%) 551 0.37827 1 0.47714 1 0.00039 0.319 0.2842 1 0.69624 1 0.24579 1 0.00383 1 0.11548 1 0.15562 1 0.0062099 1 0.29128 1 0.0096299 1 19q loss 55 (9%) 560 0.66515 1 0.1492 1 0.00165 1 0.6879 1 0.11676 1 0.43249 1 0.03386 1 0.19808 1 0.22681 1 0.075499 1 0.71961 1 0.052929 1 20p loss 66 (11%) 549 0.061429 1 0.01271 1 5e-05 0.0424 0.00193 1 0.77702 1 0.84922 1 0.26882 1 0.00341 1 0.81633 1 0.47936 1 0.01483 1 0.00158 1 20q loss 6 (1%) 609 NA NA NA NA 0.5852 1 0.82209 1 0.04246 1 1 1 0.20468 1 0.55469 1 0.40714 1 0.53151 1 NA NA NA NA 21q loss 194 (32%) 421 0.01717 1 0.02163 1 9.9999e-06 0.00935 0.02104 1 0.7049 1 0.53495 1 0.00021 0.174 0.00365 1 0.138 1 0.14684 1 0.8031 1 0.1854 1 22q loss 203 (33%) 412 0.00496 1 0.00021 0.174 9.9999e-06 0.00935 0.065489 1 0.77937 1 0.79614 1 0.01983 1 2e-05 0.0172 0.9767 1 0.068629 1 0.45934 1 0.4172 1 xq loss 81 (13%) 534 0.98685 1 0.6911 1 0.10849 1 0.34415 1 0.053029 1 0.43827 1 0.50753 1 0.66381 1 0.04378 1 0.71678 1 0.46078 1 0.0071799 1