Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.06 0.165 0.402 107.0 -9999.0 0.0 107.0 KIRREL -0.032 0.146 -9999.0 0.0 -0.585 39.0 39.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.06 0.166 -9999.0 0.0 -0.403 107.0 107.0 PLCG1 0.01 0.024 -9999.0 0.0 -0.585 1.0 1.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.057 0.155 -9999.0 0.0 -0.38 89.0 89.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.023 0.113 -9999.0 0.0 -0.348 37.0 37.0 FYN -0.042 0.128 -9999.0 0.0 -0.344 67.0 67.0 mol:Ca2+ -0.041 0.135 -9999.0 0.0 -0.366 63.0 63.0 mol:DAG -0.041 0.136 -9999.0 0.0 -0.367 63.0 63.0 NPHS2 -0.02 0.09 -9999.0 0.0 -0.47 22.0 22.0 mol:IP3 -0.041 0.136 -9999.0 0.0 -0.367 63.0 63.0 regulation of endocytosis -0.032 0.121 -9999.0 0.0 -0.325 63.0 63.0 Nephrin/NEPH1/podocin/Cholesterol -0.047 0.134 -9999.0 0.0 -0.298 121.0 121.0 establishment of cell polarity -0.06 0.165 -9999.0 0.0 -0.402 107.0 107.0 Nephrin/NEPH1/podocin/NCK1-2 -0.031 0.127 -9999.0 0.0 -0.48 18.0 18.0 Nephrin/NEPH1/beta Arrestin2 -0.032 0.123 -9999.0 0.0 -0.329 63.0 63.0 NPHS1 -0.058 0.172 -9999.0 0.0 -0.511 75.0 75.0 Nephrin/NEPH1/podocin -0.042 0.129 -9999.0 0.0 -0.346 67.0 67.0 TJP1 0.01 0.024 -9999.0 0.0 -0.585 1.0 1.0 NCK1 0.009 0.034 -9999.0 0.0 -0.585 2.0 2.0 NCK2 0.01 0.024 -9999.0 0.0 -0.585 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.041 0.136 -9999.0 0.0 -0.369 63.0 63.0 CD2AP -0.016 0.124 -9999.0 0.0 -0.58 28.0 28.0 Nephrin/NEPH1/podocin/GRB2 -0.04 0.135 -9999.0 0.0 -0.364 63.0 63.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.053 0.15 -9999.0 0.0 -0.385 78.0 78.0 cytoskeleton organization -0.027 0.133 -9999.0 0.0 -0.406 41.0 41.0 Nephrin/NEPH1 -0.041 0.12 -9999.0 0.0 -0.285 107.0 107.0 Nephrin/NEPH1/ZO-1 -0.04 0.137 -9999.0 0.0 -0.319 107.0 107.0