Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.022 0.167 -9999.0 0.0 -0.508 45.0 45.0 MAP3K8 0.009 0.031 -9999.0 0.0 -0.52 2.0 2.0 FOS -0.023 0.154 -9999.0 0.0 -0.581 30.0 30.0 PRKCA 0.01 0.031 -9999.0 0.0 -0.52 2.0 2.0 PTPN7 -0.048 0.165 -9999.0 0.0 -0.495 72.0 72.0 HRAS 0.008 0.041 -9999.0 0.0 -0.489 4.0 4.0 PRKCB -0.044 0.168 -9999.0 0.0 -0.547 60.0 60.0 NRAS 0.002 0.076 -9999.0 0.0 -0.585 10.0 10.0 RAS family/GTP 0.011 0.069 -9999.0 0.0 -0.381 16.0 16.0 MAPK3 -0.019 0.137 -9999.0 0.0 -0.576 26.0 26.0 MAP2K1 -0.009 0.122 -9999.0 0.0 -0.418 45.0 45.0 ELK1 0.01 0.025 -9999.0 0.0 -0.584 1.0 1.0 BRAF -0.015 0.121 -9999.0 0.0 -0.427 44.0 44.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 40.0 40.0 MAPK1 -0.019 0.137 -9999.0 0.0 -0.634 22.0 22.0 RAF1 -0.014 0.118 -9999.0 0.0 -0.423 43.0 43.0 KRAS 0.006 0.057 -9999.0 0.0 -0.563 6.0 6.0