Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		MIR_CNMF		MIR_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	79 (28%)	204	0.00065999	0.176	9.9999e-06	0.00283	0.00149	0.39	0.14898	1	9.9999e-06	0.00283	0.00084999	0.224	0.03759	1	0.0087499	1	0.00174	0.452	0.00164	0.428
PIK3R1	32 (11%)	251	0.75581	1	0.19257	1	0.19762	1	0.53079	1	0.63646	1	0.24711	1	0.98867	1	0.67909	1	0.40798	1	0.22321	1
RB1	24 (8%)	259	0.03343	1	0.01756	1	0.13048	1	0.92073	1	0.10826	1	0.01079	1	0.49222	1	0.22694	1	0.081269	1	0.57971	1
NF1	29 (10%)	254	0.079569	1	0.00041	0.109	0.02635	1	0.93253	1	0.0086899	1	0.068349	1	0.22934	1	0.0059599	1	0.56558	1	0.45156	1
PTEN	87 (31%)	196	0.11557	1	0.075369	1	0.02788	1	0.64341	1	0.43134	1	0.22318	1	0.37821	1	0.14368	1	0.27264	1	0.64697	1
IDH1	14 (5%)	269	0.00011	0.0298	9.9999e-06	0.00283	5.9999e-05	0.0164	0.00311	0.799	3e-05	0.00825	9.9999e-06	0.00283	0.00369	0.941	0.00125	0.329	0.00081999	0.217	2e-05	0.00554
PIK3CA	29 (10%)	254	0.79175	1	0.16215	1	0.57084	1	1	1	0.81679	1	0.82074	1	0.75638	1	0.31208	1	0.26216	1	0.23743	1
STAG2	12 (4%)	271	0.39208	1	0.69862	1	0.7155	1	0.58905	1	0.75112	1	0.04322	1	0.0070199	1	0.39524	1	0.4761	1	0.10347	1
SEMG1	8 (3%)	275	0.67995	1	0.17662	1	0.88813	1	1	1	0.16332	1	0.16813	1	NA	NA	NA	NA	1	1	0.3371	1
RPL5	7 (2%)	276	0.38077	1	0.50759	1	0.86764	1	0.46755	1	1	1	NA	NA	0.84434	1	0.6855	1	0.46457	1	1	1
SLC26A3	7 (2%)	276	0.94034	1	0.76653	1	0.465	1	0.36416	1	0.64752	1	0.18276	1	0.16639	1	0.15479	1	0.15483	1	0.1639	1
MAP3K1	6 (2%)	277	1	1	0.72969	1	0.8082	1	0.64663	1	1	1	NA	NA	NA	NA	NA	NA	0.57515	1	1	1
ATRX	16 (6%)	267	0.00206	0.534	9.9999e-06	0.00283	0.0068899	1	0.01833	1	2e-05	0.00554	4e-05	0.011	0.0058999	1	0.051479	1	0.00207	0.534	0.00022	0.0594
BRAF	6 (2%)	277	0.76943	1	0.71307	1	0.31779	1	0.02951	1	0.5903	1	NA	NA	1	1	0.64057	1	0.79233	1	1	1
EGFR	74 (26%)	209	0.0069499	1	0.055689	1	0.51003	1	0.13962	1	9.9999e-06	0.00283	0.00031	0.0831	6.9999e-05	0.019	0.00025	0.0672	0.04213	1	0.0060699	1
PDGFRA	11 (4%)	272	0.01251	1	0.14628	1	0.90471	1	0.13724	1	0.19456	1	0.73026	1	1	1	1	1	0.02626	1	0.00453	1
KDR	8 (3%)	275	0.20519	1	0.65428	1	0.27871	1	0.51323	1	0.73199	1	0.34582	1	0.14315	1	0.52574	1	NA	NA	NA	NA
TMPRSS6	6 (2%)	277	0.66795	1	0.70168	1	0.66368	1	0.26385	1	0.88101	1	0.34938	1	0.25363	1	0.32742	1	0.57175	1	1	1
CHD8	9 (3%)	274	0.70105	1	0.53148	1	0.13273	1	0.64378	1	0.18802	1	NA	NA	0.62434	1	0.75788	1	0.27364	1	0.61061	1
SEMA3C	11 (4%)	272	0.48509	1	0.17416	1	0.12053	1	0.85015	1	0.5429	1	0.41357	1	0.33909	1	0.68337	1	0.10299	1	0.16639	1
ZDHHC4	3 (1%)	280	NA	NA	NA	NA	0.16516	1	1	1	0.051739	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
MMP13	5 (2%)	278	0.91114	1	0.21789	1	0.76611	1	0.050259	1	0.15197	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
PRKCD	3 (1%)	280	0.1746	1	0.083549	1	0.16367	1	1	1	0.37963	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
REN	5 (2%)	278	0.47983	1	0.41593	1	0.073579	1	0.5164	1	0.62021	1	NA	NA	1	1	0.83434	1	NA	NA	NA	NA
LRRC55	6 (2%)	277	0.37293	1	0.53677	1	0.33593	1	0.8676	1	0.33194	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
MUC17	22 (8%)	261	0.01208	1	0.19109	1	0.70601	1	0.70319	1	0.92368	1	0.84093	1	0.24259	1	0.32571	1	0.86137	1	1	1
CD209	5 (2%)	278	0.91113	1	1	1	0.067239	1	0.60807	1	0.69125	1	NA	NA	0.4881	1	1	1	NA	NA	NA	NA
DDX5	4 (1%)	279	0.21763	1	1	1	0.53712	1	0.44495	1	0.14314	1	NA	NA	NA	NA	NA	NA	NA	NA	NA	NA
TP63	6 (2%)	277	1	1	0.73028	1	0.4095	1	0.64721	1	0.77493	1	NA	NA	0.068099	1	0.20773	1	0.25366	1	0.10966	1
CD1D	4 (1%)	279	0.8797	1	1	1	0.64343	1	0.12257	1	0.82503	1	NA	NA	0.89114	1	1	1	NA	NA	NA	NA
LZTR1	10 (4%)	273	1	1	0.51766	1	0.35992	1	0.7027	1	0.44345	1	0.12968	1	0.83957	1	0.89383	1	0.17392	1	0.75097	1
TEX15	8 (3%)	275	0.30915	1	0.24302	1	0.30013	1	0.72031	1	0.54707	1	0.8228	1	0.86791	1	0.27496	1	0.00346	0.886	0.82354	1
FBN3	11 (4%)	272	0.19107	1	0.30831	1	0.9053	1	0.92207	1	0.10636	1	1	1	0.27949	1	0.37339	1	0.85715	1	1	1