Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.011 0.098 0.301 13.0 -9999.0 0.0 13.0 KIRREL -0.005 0.127 -9999.0 0.0 -0.412 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.011 0.099 -9999.0 0.0 -0.302 13.0 13.0 PLCG1 0.026 0.037 -9999.0 0.0 -0.403 1.0 1.0 ARRB2 0.031 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.015 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.039 0.089 -9999.0 0.0 -0.228 13.0 13.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.002 0.061 -9999.0 0.0 -0.22 9.0 9.0 FYN -0.019 0.076 0.151 11.0 -0.217 13.0 24.0 mol:Ca2+ 0.033 0.093 -9999.0 0.0 -0.242 13.0 13.0 mol:DAG 0.034 0.094 -9999.0 0.0 -0.243 13.0 13.0 NPHS2 -0.0 0.033 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.034 0.094 -9999.0 0.0 -0.243 13.0 13.0 regulation of endocytosis 0.027 0.077 -9999.0 0.0 -0.208 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol 0.025 0.081 -9999.0 0.0 -0.223 13.0 13.0 establishment of cell polarity 0.011 0.098 -9999.0 0.0 -0.301 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 0.055 0.09 -9999.0 0.0 -0.212 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 0.029 0.078 -9999.0 0.0 -0.21 13.0 13.0 NPHS1 0.0 0.033 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin 0.023 0.077 -9999.0 0.0 -0.218 13.0 13.0 TJP1 0.031 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.031 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.032 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.036 0.094 -9999.0 0.0 -0.244 13.0 13.0 CD2AP 0.031 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.043 0.086 -9999.0 0.0 -0.228 12.0 12.0 GRB2 0.031 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.035 0.095 0.155 12.0 -0.223 22.0 34.0 cytoskeleton organization -0.018 0.062 0.195 1.0 -0.246 8.0 9.0 Nephrin/NEPH1 0.014 0.069 -9999.0 0.0 -0.205 13.0 13.0 Nephrin/NEPH1/ZO-1 0.028 0.086 -9999.0 0.0 -0.239 13.0 13.0