Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 70 (13%) 452 0.00013 0.0894 0.0097899 1 0.99217 1 0.62538 1 0.88711 1 0.9422 1 0.68747 1 0.0052099 1 0.11905 1 0.87359 1 1q gain 121 (23%) 401 9.9999e-06 0.008 9.9999e-06 0.008 0.28963 1 0.76977 1 2e-04 0.135 0.00018 0.122 0.00045 0.297 0.00031 0.208 0.01148 1 0.096169 1 2p gain 97 (19%) 425 9.9999e-06 0.008 9.9999e-06 0.008 0.02315 1 0.4372 1 0.054309 1 0.00128 0.817 0.02082 1 0.01968 1 0.0024 1 0.089349 1 2q gain 74 (14%) 448 9.9999e-06 0.008 9.9999e-06 0.008 0.38707 1 0.72901 1 0.069879 1 0.00027 0.182 0.10505 1 0.10199 1 0.01721 1 0.03961 1 3p gain 81 (16%) 441 0.19678 1 0.00033 0.221 0.1314 1 0.75738 1 0.00479 1 0.082389 1 0.13067 1 0.15389 1 0.11329 1 0.02884 1 3q gain 254 (49%) 268 5e-05 0.0351 9.9999e-06 0.008 0.69738 1 0.27903 1 3e-04 0.202 0.02511 1 0.0084499 1 0.80346 1 0.02161 1 0.095889 1 4p gain 41 (8%) 481 0.02247 1 0.00197 1 0.69425 1 0.35575 1 0.10466 1 0.37393 1 0.073709 1 0.6455 1 0.73284 1 0.32481 1 4q gain 37 (7%) 485 0.90168 1 0.19844 1 1 1 0.76609 1 0.67958 1 0.12867 1 1 1 0.90883 1 0.68361 1 0.73842 1 5p gain 201 (39%) 321 9.9999e-06 0.008 0.00224 1 0.96156 1 0.83378 1 0.11228 1 0.43817 1 0.5731 1 0.0328 1 0.83657 1 0.66117 1 5q gain 68 (13%) 454 0.04884 1 0.5954 1 0.6176 1 0.8881 1 0.76106 1 0.75831 1 0.67318 1 0.4489 1 0.85951 1 0.31081 1 6p gain 83 (16%) 439 0.00036 0.24 0.00225 1 0.49873 1 0.74539 1 0.65892 1 0.037 1 0.60518 1 0.071259 1 0.32041 1 0.6598 1 6q gain 63 (12%) 459 0.00261 1 0.03038 1 0.19249 1 0.073489 1 0.076439 1 0.03153 1 0.24046 1 0.91315 1 0.065029 1 0.2976 1 7p gain 183 (35%) 339 9.9999e-06 0.008 9.9999e-06 0.008 0.63128 1 0.50401 1 0.26189 1 0.11545 1 0.68714 1 9.9999e-06 0.008 0.12273 1 0.53332 1 7q gain 129 (25%) 393 9.9999e-06 0.008 9.9999e-06 0.008 0.17522 1 0.63276 1 0.54181 1 0.87647 1 0.01245 1 6.9999e-05 0.0488 0.32633 1 0.50296 1 8p gain 155 (30%) 367 0.02294 1 0.247 1 0.5858 1 0.64185 1 0.52494 1 0.22489 1 0.5974 1 0.78695 1 0.45146 1 0.13375 1 8q gain 310 (59%) 212 3e-05 0.0215 3e-05 0.0215 0.081319 1 0.88901 1 0.17801 1 0.00428 1 0.17329 1 0.01094 1 0.03942 1 0.068379 1 9p gain 102 (20%) 420 9.9999e-06 0.008 2e-05 0.0145 0.38983 1 0.094359 1 0.00187 1 0.01571 1 0.0072399 1 0.0096599 1 7.9999e-05 0.0557 0.15704 1 9q gain 139 (27%) 383 9.9999e-06 0.008 0.00323 1 0.17519 1 0.25518 1 0.28503 1 0.01835 1 0.39822 1 0.051069 1 0.29713 1 0.44144 1 10p gain 40 (8%) 482 0.075759 1 3e-05 0.0215 0.59163 1 0.065919 1 0.03932 1 0.00017 0.116 0.0445 1 0.01557 1 0.55687 1 0.36458 1 10q gain 34 (7%) 488 0.00452 1 0.24122 1 0.097039 1 0.40194 1 0.62282 1 0.15994 1 0.87623 1 0.038 1 0.21727 1 0.61371 1 11p gain 66 (13%) 456 0.00013 0.0894 2e-05 0.0145 0.82683 1 0.41078 1 0.13374 1 0.077989 1 0.04547 1 0.26585 1 0.003 1 0.0082399 1 11q gain 71 (14%) 451 0.00013 0.0894 3e-05 0.0215 0.57618 1 0.58338 1 0.15419 1 0.03025 1 0.27532 1 0.01648 1 0.01807 1 0.062319 1 12p gain 148 (28%) 374 9.9999e-06 0.008 9.9999e-06 0.008 0.01638 1 0.82177 1 0.01586 1 0.00201 1 0.01225 1 0.097349 1 0.03882 1 0.52295 1 12q gain 89 (17%) 433 2e-05 0.0145 0.00092999 0.599 0.14215 1 0.18319 1 0.073839 1 0.00291 1 0.66422 1 0.78312 1 0.45001 1 0.79234 1 13q gain 57 (11%) 465 9.9999e-06 0.008 0.00266 1 0.59462 1 0.73384 1 0.02321 1 0.03834 1 0.12336 1 0.24115 1 0.02748 1 0.01566 1 14q gain 151 (29%) 371 9.9999e-06 0.008 9.9999e-06 0.008 0.21698 1 0.097089 1 0.01922 1 0.00064999 0.424 0.0070399 1 0.00038 0.253 5e-05 0.0351 0.00050999 0.336 15q gain 72 (14%) 450 7.9999e-05 0.0557 0.0068999 1 0.38531 1 0.58554 1 0.21531 1 0.56777 1 0.8857 1 0.0062299 1 0.03417 1 0.52412 1 16p gain 107 (20%) 415 9.9999e-06 0.008 9.9999e-06 0.008 0.3316 1 0.17609 1 0.38509 1 0.0053499 1 0.86708 1 2e-05 0.0145 0.47845 1 0.53963 1 16q gain 107 (20%) 415 9.9999e-06 0.008 2e-05 0.0145 0.58406 1 0.81663 1 0.17472 1 0.005 1 0.28944 1 3e-05 0.0215 0.089709 1 0.1939 1 17p gain 67 (13%) 455 9.9999e-06 0.008 3e-05 0.0215 0.59771 1 0.90337 1 0.0078599 1 0.01296 1 0.056939 1 0.04731 1 0.24682 1 0.16824 1 17q gain 87 (17%) 435 9.9999e-06 0.008 0.00063999 0.419 0.58474 1 0.67729 1 0.12858 1 0.03116 1 0.41688 1 0.00355 1 0.061909 1 0.099669 1 18p gain 123 (24%) 399 9.9999e-06 0.008 9.9999e-06 0.008 0.33122 1 0.31818 1 0.37633 1 9.9999e-06 0.008 0.24763 1 0.01534 1 0.00086999 0.562 0.16319 1 18q gain 53 (10%) 469 0.0016 1 2e-05 0.0145 0.0070199 1 0.087659 1 0.00102 0.654 0.00016 0.109 3e-05 0.0215 0.14257 1 4e-05 0.0282 0.061589 1 19p gain 56 (11%) 466 0.0132 1 3e-05 0.0215 0.087889 1 0.76718 1 0.01171 1 0.00022 0.149 0.00036 0.24 0.052769 1 0.40303 1 0.18178 1 19q gain 78 (15%) 444 0.37245 1 0.00031 0.208 0.96185 1 0.78506 1 0.01693 1 0.00078999 0.511 0.00053999 0.355 0.078839 1 0.49716 1 0.064699 1 20p gain 190 (36%) 332 9.9999e-06 0.008 4e-05 0.0282 0.89667 1 0.73293 1 0.10351 1 0.0252 1 0.093119 1 0.01317 1 0.50928 1 0.04061 1 20q gain 201 (39%) 321 9.9999e-06 0.008 9.9999e-06 0.008 0.83933 1 0.87213 1 0.074199 1 0.00042 0.278 0.063159 1 0.00408 1 0.03441 1 0.01141 1 21q gain 35 (7%) 487 0.063809 1 0.04019 1 0.01423 1 0.12718 1 0.0073199 1 0.0093599 1 0.095339 1 0.25188 1 0.0055999 1 0.76988 1 22q gain 112 (21%) 410 9.9999e-06 0.008 9.9999e-06 0.008 0.15564 1 0.51731 1 0.2717 1 0.41778 1 0.00036 0.24 0.081679 1 0.01312 1 0.52922 1 xq gain 90 (17%) 432 0.00013 0.0894 0.00094999 0.611 0.25343 1 0.82467 1 0.42829 1 0.36867 1 0.12563 1 0.50492 1 0.03026 1 0.29091 1 1p loss 58 (11%) 464 9.9999e-06 0.008 9.9999e-06 0.008 0.03154 1 0.16807 1 0.00168 1 0.00475 1 0.40291 1 0.087499 1 0.26445 1 0.02063 1 1q loss 39 (7%) 483 0.01581 1 0.13882 1 0.77988 1 0.48716 1 0.054309 1 0.01232 1 0.094679 1 0.00074999 0.488 0.40877 1 0.5118 1 2p loss 33 (6%) 489 0.0285 1 0.0057099 1 0.16049 1 0.04421 1 0.082899 1 0.42842 1 0.057129 1 0.67169 1 0.19891 1 0.3696 1 2q loss 46 (9%) 476 0.47373 1 0.21487 1 0.87145 1 0.6736 1 0.73238 1 0.54763 1 0.15189 1 0.6888 1 0.40297 1 0.16296 1 3p loss 297 (57%) 225 9.9999e-06 0.008 9.9999e-06 0.008 0.9421 1 0.67633 1 0.0242 1 7.9999e-05 0.0557 0.097799 1 0.00076999 0.499 5.9999e-05 0.0419 0.23456 1 3q loss 61 (12%) 461 0.0093199 1 0.22933 1 0.33757 1 0.75862 1 0.68132 1 0.202 1 1 1 0.0072399 1 0.36258 1 0.94738 1 4p loss 194 (37%) 328 9.9999e-06 0.008 9.9999e-06 0.008 0.062199 1 0.55039 1 0.00053999 0.355 0.00012 0.0829 0.18338 1 0.02725 1 0.00061999 0.406 0.065639 1 4q loss 151 (29%) 371 9.9999e-06 0.008 9.9999e-06 0.008 0.47195 1 0.22447 1 0.01565 1 0.00188 1 0.25802 1 0.091219 1 0.03009 1 0.16119 1 5p loss 51 (10%) 471 3e-05 0.0215 9.9999e-06 0.008 0.41955 1 0.38463 1 0.58513 1 0.12816 1 0.40864 1 0.25714 1 0.093629 1 0.02496 1 5q loss 164 (31%) 358 9.9999e-06 0.008 9.9999e-06 0.008 0.24162 1 0.77326 1 0.22587 1 9.9999e-06 0.008 0.38829 1 0.00024 0.162 0.00019 0.129 0.077139 1 6p loss 68 (13%) 454 0.00043 0.284 0.00088999 0.574 0.02799 1 0.12748 1 0.02964 1 0.03709 1 0.3074 1 0.6858 1 0.73879 1 0.076749 1 6q loss 68 (13%) 454 0.04542 1 0.00371 1 0.12709 1 0.12227 1 0.78663 1 0.5726 1 0.75888 1 0.37298 1 0.7661 1 0.02178 1 7p loss 29 (6%) 493 0.02987 1 0.0068399 1 0.01064 1 0.62724 1 0.29901 1 0.03404 1 0.25594 1 0.76121 1 0.02138 1 0.77561 1 7q loss 40 (8%) 482 0.36647 1 0.30159 1 0.52851 1 1 1 0.26111 1 0.066049 1 0.10083 1 0.9348 1 0.74682 1 0.28703 1 8p loss 187 (36%) 335 9.9999e-06 0.008 9.9999e-06 0.008 0.54745 1 0.67796 1 0.071379 1 0.0122 1 0.13981 1 0.00273 1 0.00015 0.102 5e-05 0.0351 8q loss 30 (6%) 492 0.02354 1 0.28793 1 0.75816 1 0.87419 1 0.63925 1 0.15978 1 0.37412 1 0.41544 1 0.65215 1 0.26516 1 9p loss 186 (36%) 336 9.9999e-06 0.008 9.9999e-06 0.008 0.66713 1 0.11377 1 0.34353 1 0.00012 0.0829 0.056869 1 3e-05 0.0215 3e-05 0.0215 0.60067 1 9q loss 87 (17%) 435 9.9999e-06 0.008 9.9999e-06 0.008 0.97613 1 0.97073 1 0.38797 1 0.23502 1 0.42287 1 0.00365 1 0.01256 1 0.30914 1 10p loss 156 (30%) 366 9.9999e-06 0.008 0.00337 1 0.32101 1 0.23076 1 0.052249 1 0.083189 1 0.065609 1 0.091089 1 0.02258 1 0.24032 1 10q loss 113 (22%) 409 9.9999e-06 0.008 0.00070999 0.463 0.20776 1 0.30247 1 0.01409 1 0.01022 1 0.02888 1 0.14582 1 0.12128 1 0.16432 1 11p loss 141 (27%) 381 9.9999e-06 0.008 0.00012 0.0829 0.32016 1 0.33294 1 0.0057299 1 0.14204 1 0.00372 1 0.12086 1 0.094789 1 0.2324 1 11q loss 172 (33%) 350 9.9999e-06 0.008 9.9999e-06 0.008 0.17591 1 0.078979 1 0.0053299 1 5.9999e-05 0.0419 0.10743 1 0.42785 1 0.15246 1 0.50684 1 12p loss 37 (7%) 485 0.73054 1 0.04989 1 0.62875 1 0.10973 1 0.93017 1 0.81557 1 0.81898 1 0.79857 1 0.34058 1 0.28424 1 12q loss 33 (6%) 489 0.04626 1 0.00113 0.723 0.86273 1 0.096459 1 0.3842 1 0.92309 1 1 1 0.18993 1 0.30173 1 0.21619 1 13q loss 167 (32%) 355 9.9999e-06 0.008 9.9999e-06 0.008 0.38556 1 0.82504 1 0.00442 1 0.00145 0.924 0.03935 1 0.19211 1 0.10735 1 0.19999 1 14q loss 58 (11%) 464 0.062869 1 0.00329 1 0.03464 1 0.52815 1 4e-05 0.0282 0.00038 0.253 0.00044 0.29 0.31143 1 2e-05 0.0145 0.01286 1 15q loss 103 (20%) 419 9.9999e-06 0.008 0.16671 1 0.62841 1 0.3461 1 0.12185 1 0.28788 1 0.60571 1 0.27148 1 0.078989 1 0.93987 1 16p loss 63 (12%) 459 2e-05 0.0145 0.01135 1 0.86518 1 0.079379 1 0.00228 1 0.058479 1 0.65975 1 0.63365 1 0.17927 1 0.89634 1 16q loss 81 (16%) 441 0.00238 1 9.9999e-06 0.008 0.47479 1 0.24276 1 9.9999e-06 0.008 9.9999e-06 0.008 0.0080699 1 0.0082499 1 9.9999e-06 0.008 0.00245 1 17p loss 107 (20%) 415 0.00014 0.0958 0.00095999 0.616 0.38843 1 0.75863 1 0.52847 1 0.11747 1 0.39459 1 0.10909 1 0.34294 1 0.8574 1 17q loss 34 (7%) 488 0.01378 1 0.1134 1 0.90371 1 0.50615 1 0.4427 1 0.85066 1 0.74229 1 0.94736 1 0.87118 1 0.5457 1 18p loss 104 (20%) 418 0.00164 1 2e-05 0.0145 0.54096 1 0.33055 1 0.27289 1 0.11123 1 0.61823 1 0.01264 1 0.22277 1 0.57979 1 18q loss 211 (40%) 311 9.9999e-06 0.008 9.9999e-06 0.008 0.21278 1 0.33239 1 0.0016 1 9.9999e-06 0.008 0.00074999 0.488 2e-05 0.0145 7.9999e-05 0.0557 0.053229 1 19p loss 98 (19%) 424 9.9999e-06 0.008 0.00014 0.0958 0.71209 1 0.71603 1 0.02273 1 0.0070699 1 0.02201 1 0.00408 1 0.01007 1 0.03679 1 19q loss 86 (16%) 436 9.9999e-06 0.008 2e-05 0.0145 0.12838 1 0.51886 1 0.20514 1 0.089599 1 0.1545 1 0.03237 1 0.1727 1 0.04142 1 20p loss 47 (9%) 475 9.9999e-06 0.008 0.02628 1 0.49372 1 0.77354 1 0.11515 1 0.34902 1 0.32501 1 0.0219 1 0.11607 1 0.096009 1 20q loss 28 (5%) 494 0.00039 0.259 0.0053399 1 0.20988 1 0.75647 1 0.01556 1 0.01306 1 0.069739 1 0.04767 1 0.01795 1 0.03039 1 21q loss 184 (35%) 338 9.9999e-06 0.008 9.9999e-06 0.008 0.57502 1 0.98332 1 0.03395 1 0.03396 1 0.30193 1 0.00033 0.221 0.00075999 0.493 0.23282 1 22q loss 75 (14%) 447 9.9999e-05 0.0692 0.00311 1 0.66698 1 0.65608 1 0.00122 0.78 0.15885 1 0.00157 0.999 0.51767 1 0.01751 1 0.04728 1 xq loss 86 (16%) 436 9.9999e-06 0.008 9.9999e-06 0.008 0.084709 1 0.00184 1 0.03028 1 0.0050399 1 0.00348 1 0.11213 1 0.37332 1 0.7537 1