Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	213 (70%)	93	9.9999e-06	0.0027	9.9999e-06	0.0027	0.084509	1	0.89023	1	0.0087999	1	5e-05	0.0131	0.0085299	1	9.9999e-06	0.0027	0.00444	1	0.00316	0.784
CDKN2A	65 (21%)	241	0.29386	1	0.00038	0.0969	0.00106	0.268	0.53618	1	0.18616	1	0.39354	1	0.50692	1	0.15476	1	0.23145	1	0.2691	1
CASP8	27 (9%)	279	2e-05	0.00526	9.9999e-06	0.0027	0.0146	1	0.3842	1	9.9999e-06	0.0027	0.00011	0.0286	0.13413	1	0.93346	1	0.094329	1	0.34924	1
FAT1	69 (23%)	237	0.12376	1	0.078979	1	0.91732	1	0.48034	1	0.10612	1	0.32612	1	0.33765	1	0.50571	1	0.28851	1	0.21028	1
MLL2	53 (17%)	253	0.00086999	0.221	0.0483	1	0.49337	1	0.34647	1	0.082329	1	0.10563	1	0.10695	1	0.02444	1	0.50739	1	0.064469	1
JUB	18 (6%)	288	0.25656	1	0.080499	1	0.39667	1	0.74576	1	0.12083	1	0.42319	1	0.12897	1	1	1	0.12565	1	0.84943	1
NOTCH1	57 (19%)	249	0.0222	1	0.00152	0.38	0.055379	1	0.069079	1	0.002	0.498	0.00011	0.0286	8.9999e-05	0.0235	0.34757	1	0.31415	1	0.02052	1
NFE2L2	17 (6%)	289	0.6297	1	0.00013	0.0335	0.35014	1	0.6847	1	1	1	0.43406	1	0.17988	1	0.7375	1	0.3561	1	0.92023	1
NSD1	33 (11%)	273	0.34393	1	9.9999e-06	0.0027	0.095499	1	0.0066799	1	0.00034	0.087	9.9999e-06	0.0027	0.01136	1	0.00426	1	0.0098399	1	0.0086899	1
HRAS	10 (3%)	296	0.00024	0.0617	0.0050899	1	0.38742	1	0.34345	1	0.00139	0.349	0.01448	1	0.15651	1	0.27203	1	0.51825	1	0.85061	1
ZNF750	13 (4%)	293	0.45176	1	0.13664	1	0.80386	1	0.33012	1	0.080969	1	0.070039	1	0.72074	1	0.93751	1	0.18131	1	1	1
RASA1	14 (5%)	292	0.25221	1	0.12955	1	0.37565	1	0.71504	1	0.34797	1	0.5462	1	0.471	1	0.13991	1	0.27275	1	0.060979	1
HLA-A	9 (3%)	297	0.03393	1	0.31705	1	1	1	0.63853	1	0.18556	1	0.070279	1	0.34649	1	0.43057	1	0.673	1	0.85202	1
EPHA2	13 (4%)	293	0.30574	1	0.00135	0.34	0.74075	1	0.93243	1	0.063829	1	0.19701	1	0.48506	1	0.39787	1	0.080469	1	0.24759	1
RAC1	9 (3%)	297	0.31047	1	0.43486	1	1	1	0.83631	1	0.19049	1	0.14654	1	0.26173	1	0.19898	1	0.25568	1	0.2706	1
EP300	24 (8%)	282	0.33912	1	0.46704	1	0.57197	1	0.088149	1	0.00481	1	0.058419	1	0.38197	1	0.21175	1	0.22713	1	1	1
TGFBR2	10 (3%)	296	0.37602	1	0.01131	1	0.43817	1	0.90066	1	0.22947	1	0.04445	1	0.77464	1	0.51448	1	0.93275	1	0.52011	1
PIK3CA	64 (21%)	242	0.2411	1	0.03919	1	0.69575	1	0.04832	1	0.096479	1	0.053509	1	0.0056999	1	0.064389	1	0.20281	1	0.23009	1
FBXW7	15 (5%)	291	0.77534	1	0.46951	1	0.41427	1	0.11238	1	0.63269	1	0.87584	1	0.94612	1	0.20641	1	0.87575	1	0.27184	1
RB1	10 (3%)	296	0.092029	1	0.38495	1	0.32642	1	0.27482	1	0.056219	1	0.37695	1	0.10343	1	0.51823	1	0.43974	1	0.85206	1
CTCF	11 (4%)	295	0.23157	1	0.03605	1	0.6142	1	0.46943	1	0.42571	1	0.52583	1	0.62724	1	0.46247	1	0.77933	1	1	1
KDM6A	8 (3%)	298	0.01754	1	0.6317	1	0.15837	1	1	1	0.90812	1	0.36134	1	0.38179	1	0.74096	1	0.14475	1	0.16088	1
ELF4	5 (2%)	301	0.03607	1	0.17298	1	0.35766	1	0.34133	1	0.61873	1	1	1	0.29743	1	0.37694	1	0.58802	1	1	1
RHOA	4 (1%)	302	0.01514	1	0.16419	1	0.13733	1	0.24059	1	0.82337	1	0.48658	1	0.16669	1	0.46181	1	0.39567	1	0.03751	1
HLA-B	8 (3%)	298	0.21708	1	0.4015	1	1	1	0.053149	1	0.0083099	1	0.14656	1	0.38153	1	0.063559	1	0.56073	1	0.65878	1
PRSS1	7 (2%)	299	0.49365	1	0.85305	1	0.87166	1	0.61635	1	0.72137	1	0.57665	1	1	1	0.0131	1	0.71257	1	0.42934	1
GUCY2F	8 (3%)	298	0.88429	1	0.95911	1	0.83219	1	0.83299	1	0.66572	1	0.88019	1	0.15398	1	0.81982	1	0.02067	1	0.65787	1