Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.063 0.189 0.597 52.0 -9999.0 0.0 52.0 KIRREL -0.022 0.138 -9999.0 0.0 -0.623 24.0 24.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.064 0.19 -9999.0 0.0 -0.598 52.0 52.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.057 0.174 -9999.0 0.0 -0.577 41.0 41.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.009 0.123 -9999.0 0.0 -0.602 10.0 10.0 FYN -0.036 0.167 -9999.0 0.0 -0.525 42.0 42.0 mol:Ca2+ -0.057 0.172 -9999.0 0.0 -0.57 41.0 41.0 mol:DAG -0.057 0.173 -9999.0 0.0 -0.573 41.0 41.0 NPHS2 -0.023 0.133 -9999.0 0.0 -0.858 12.0 12.0 mol:IP3 -0.057 0.173 -9999.0 0.0 -0.573 41.0 41.0 regulation of endocytosis -0.039 0.155 -9999.0 0.0 -0.794 10.0 10.0 Nephrin/NEPH1/podocin/Cholesterol -0.058 0.177 -9999.0 0.0 -0.585 41.0 41.0 establishment of cell polarity -0.063 0.189 -9999.0 0.0 -0.597 52.0 52.0 Nephrin/NEPH1/podocin/NCK1-2 -0.052 0.161 -9999.0 0.0 -0.553 34.0 34.0 Nephrin/NEPH1/beta Arrestin2 -0.026 0.161 -9999.0 0.0 -0.813 10.0 10.0 NPHS1 -0.049 0.207 -9999.0 0.0 -0.835 32.0 32.0 Nephrin/NEPH1/podocin -0.052 0.163 -9999.0 0.0 -0.529 42.0 42.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.057 0.174 -9999.0 0.0 -0.577 41.0 41.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.057 0.174 -9999.0 0.0 -0.577 41.0 41.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.065 0.208 -9999.0 0.0 -0.54 70.0 70.0 cytoskeleton organization -0.013 0.157 -9999.0 0.0 -0.78 10.0 10.0 Nephrin/NEPH1 -0.047 0.144 -9999.0 0.0 -0.516 36.0 36.0 Nephrin/NEPH1/ZO-1 -0.052 0.156 -9999.0 0.0 -0.562 36.0 36.0