Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.0 0.106 0.317 47.0 -9999.0 0.0 47.0 KIRREL 0.002 0.1 -9999.0 0.0 -0.451 22.0 22.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.0 0.107 -9999.0 0.0 -0.318 47.0 47.0 PLCG1 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.023 0.097 -9999.0 0.0 -0.304 22.0 22.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.001 0.062 -9999.0 0.0 -0.258 18.0 18.0 FYN -0.016 0.085 0.27 9.0 -0.28 23.0 32.0 mol:Ca2+ 0.021 0.094 -9999.0 0.0 -0.299 21.0 21.0 mol:DAG 0.022 0.095 -9999.0 0.0 -0.3 21.0 21.0 NPHS2 -0.025 0.064 -9999.0 0.0 -0.408 12.0 12.0 mol:IP3 0.022 0.095 -9999.0 0.0 -0.3 21.0 21.0 regulation of endocytosis 0.02 0.084 -9999.0 0.0 -0.269 21.0 21.0 Nephrin/NEPH1/podocin/Cholesterol 0.01 0.092 -9999.0 0.0 -0.245 52.0 52.0 establishment of cell polarity 0.0 0.106 -9999.0 0.0 -0.317 47.0 47.0 Nephrin/NEPH1/podocin/NCK1-2 0.031 0.089 -9999.0 0.0 -0.356 8.0 8.0 Nephrin/NEPH1/beta Arrestin2 0.022 0.085 -9999.0 0.0 -0.275 20.0 20.0 NPHS1 -0.022 0.1 -9999.0 0.0 -0.407 29.0 29.0 Nephrin/NEPH1/podocin 0.014 0.086 -9999.0 0.0 -0.277 24.0 24.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.023 0.011 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.023 0.096 -9999.0 0.0 -0.301 21.0 21.0 CD2AP 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.024 0.098 -9999.0 0.0 -0.302 23.0 23.0 GRB2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.03 0.096 0.28 7.0 -0.254 48.0 55.0 cytoskeleton organization -0.01 0.071 0.23 3.0 -0.298 17.0 20.0 Nephrin/NEPH1 0.005 0.076 -9999.0 0.0 -0.22 46.0 46.0 Nephrin/NEPH1/ZO-1 0.018 0.091 -9999.0 0.0 -0.253 46.0 46.0