Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 3p gain 8 (12%) 58 0.27195 1 0.53033 1 0.95114 1 0.6473 1 0.51571 1 0.69136 1 0.66904 1 0.59999 1 3q gain 8 (12%) 58 0.26987 1 0.52957 1 0.95158 1 0.64804 1 0.51487 1 0.69013 1 0.66904 1 0.60241 1 4p gain 24 (36%) 42 0.055439 1 1 1 2e-05 0.00934 5.9999e-05 0.0272 0.76896 1 0.0090299 1 0.034911 1 0.01727 1 4q gain 24 (36%) 42 0.055619 1 1 1 2e-05 0.00934 5e-05 0.0228 0.772 1 0.0090799 1 0.034911 1 0.01731 1 5p gain 8 (12%) 58 0.42406 1 0.68071 1 0.44848 1 0.44342 1 0.36738 1 0.058429 1 1 1 0.12623 1 5q gain 8 (12%) 58 0.42353 1 0.68324 1 0.44897 1 0.44533 1 0.36201 1 0.060189 1 1 1 0.12705 1 7p gain 24 (36%) 42 0.15025 1 1 1 0.01595 1 0.060879 1 0.89945 1 0.11732 1 0.76563 1 0.099089 1 7q gain 24 (36%) 42 0.1518 1 1 1 0.01663 1 0.061799 1 0.90114 1 0.11922 1 0.76563 1 0.099529 1 8p gain 17 (26%) 49 0.41274 1 0.4166 1 0.0036 1 0.03173 1 0.46361 1 0.10088 1 1 1 0.02922 1 8q gain 18 (27%) 48 0.34331 1 0.37658 1 0.00108 0.459 0.0096399 1 0.69618 1 0.087789 1 0.75145 1 0.04241 1 9p gain 10 (15%) 56 1 1 1 1 0.72326 1 0.81294 1 0.83347 1 0.60156 1 1 1 0.26495 1 9q gain 10 (15%) 56 1 1 1 1 0.72306 1 0.81278 1 0.83116 1 0.5991 1 1 1 0.26247 1 10p gain 4 (6%) 62 0.44138 1 0.16246 1 0.51671 1 0.20361 1 1 1 0.16666 1 1 1 0.45758 1 11p gain 15 (23%) 51 0.2801 1 0.67633 1 3e-05 0.0138 0.00023 0.102 0.87058 1 0.02788 1 0.19654 1 0.078869 1 11q gain 15 (23%) 51 0.28111 1 0.67857 1 9.9999e-06 0.00488 5e-05 0.0228 0.61818 1 0.01933 1 0.19654 1 0.10417 1 12p gain 19 (29%) 47 0.48059 1 0.76675 1 0.079689 1 0.15793 1 1 1 0.066689 1 0.2129 1 0.15575 1 12q gain 20 (30%) 46 0.44387 1 0.59497 1 0.14515 1 0.082419 1 0.94282 1 0.03226 1 0.23522 1 0.1321 1 14q gain 21 (32%) 45 0.10626 1 0.82924 1 0.00086999 0.373 0.0051399 1 0.42651 1 0.056599 1 0.031178 1 0.077319 1 15q gain 21 (32%) 45 0.10631 1 0.83041 1 0.00171 0.718 0.062129 1 0.75677 1 0.21528 1 0.76221 1 0.47251 1 16p gain 21 (32%) 45 0.10694 1 1 1 2e-05 0.00934 7.9999e-05 0.0361 0.15922 1 0.0054099 1 0.031178 1 0.0073999 1 16q gain 21 (32%) 45 0.10628 1 1 1 2e-05 0.00934 8.9999e-05 0.0405 0.16155 1 0.0053099 1 0.031178 1 0.0071399 1 18p gain 17 (26%) 49 0.51831 1 0.80545 1 0.00194 0.811 0.01298 1 0.93744 1 0.04953 1 0.34059 1 0.0472 1 18q gain 16 (24%) 50 0.63997 1 0.92645 1 0.00099999 0.428 0.01891 1 0.82119 1 0.051909 1 0.11865 1 0.062299 1 19p gain 19 (29%) 47 0.48303 1 0.27349 1 0.02152 1 0.0079899 1 0.65999 1 0.03903 1 1 1 0.70808 1 19q gain 17 (26%) 49 0.51769 1 0.31034 1 0.00137 0.578 0.00166 0.699 0.41129 1 0.04749 1 1 1 0.65482 1 20p gain 20 (30%) 46 0.21575 1 0.59459 1 0.0296 1 0.03173 1 0.70826 1 0.03054 1 0.53518 1 0.18197 1 20q gain 21 (32%) 45 0.22689 1 0.38627 1 0.067539 1 0.01676 1 0.67677 1 0.03691 1 0.76221 1 0.099059 1 21q gain 4 (6%) 62 0.43842 1 0.16275 1 0.51255 1 0.10628 1 0.67444 1 0.16542 1 1 1 0.40952 1 22q gain 19 (29%) 47 0.90138 1 0.71191 1 0.069979 1 0.36105 1 0.55151 1 0.02332 1 1 1 0.0093499 1 xq gain 6 (9%) 60 1 1 0.72179 1 0.0067599 1 0.12122 1 0.26353 1 0.11844 1 0.14179 1 0.071419 1 1p loss 53 (80%) 13 0.67192 1 2e-05 0.00934 0.00048 0.209 0.00033 0.145 0.16225 1 0.0013 0.55 0.17642 1 0.00411 1 1q loss 52 (79%) 14 0.47373 1 9.9999e-06 0.00488 6.9999e-05 0.0317 5e-05 0.0228 0.2315 1 0.00050999 0.221 0.17642 1 0.00402 1 2p loss 46 (70%) 20 0.088819 1 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 0.081469 1 9.9999e-06 0.00488 0.030584 1 0.00072999 0.314 2q loss 46 (70%) 20 0.088809 1 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 0.081359 1 9.9999e-06 0.00488 0.030584 1 0.00061999 0.268 3p loss 9 (14%) 57 0.03616 1 0.89472 1 0.064469 1 0.00299 1 0.90293 1 0.20048 1 0.3805 1 0.84522 1 3q loss 8 (12%) 58 0.02068 1 0.36729 1 0.02428 1 0.00187 0.784 0.57135 1 0.1821 1 0.14179 1 0.68866 1 5p loss 10 (15%) 56 0.098399 1 0.25266 1 0.00065999 0.284 0.01934 1 0.42507 1 0.01467 1 0.45109 1 0.34359 1 5q loss 10 (15%) 56 0.099149 1 0.25344 1 0.00062999 0.272 0.0191 1 0.42545 1 0.01444 1 0.45109 1 0.34531 1 6p loss 51 (77%) 15 0.33151 1 0.00014 0.0626 3e-05 0.0138 9.9999e-06 0.00488 0.35198 1 0.00118 0.5 0.17642 1 4e-04 0.175 6q loss 51 (77%) 15 0.33094 1 0.00016 0.071 3e-05 0.0138 9.9999e-06 0.00488 0.35137 1 0.00104 0.444 0.17642 1 0.00032 0.14 8p loss 9 (14%) 57 9.9999e-06 0.00488 0.083779 1 0.054699 1 0.03874 1 0.14983 1 0.46737 1 0.14179 1 0.31968 1 8q loss 8 (12%) 58 2e-05 0.00934 0.04464 1 0.13379 1 0.071779 1 0.28963 1 0.52897 1 0.14179 1 0.32037 1 9p loss 10 (15%) 56 1 1 0.90375 1 0.064389 1 0.01633 1 0.90947 1 0.60261 1 0.69505 1 0.89077 1 9q loss 10 (15%) 56 1 1 0.9027 1 0.063669 1 0.01677 1 0.91157 1 0.6011 1 0.69505 1 0.89012 1 10p loss 48 (73%) 18 0.34303 1 0.00029 0.128 6.9999e-05 0.0317 9.9999e-06 0.00488 0.2757 1 0.00014 0.0626 0.75898 1 0.01015 1 10q loss 49 (74%) 17 0.24653 1 0.00031 0.136 2e-05 0.00934 9.9999e-06 0.00488 0.22451 1 2e-04 0.0886 0.53841 1 0.00338 1 11p loss 7 (11%) 59 0.63054 1 0.57496 1 0.10908 1 0.31684 1 0.20534 1 0.93678 1 0.3805 1 0.5789 1 11q loss 7 (11%) 59 0.62758 1 0.57282 1 0.10928 1 0.31659 1 0.20435 1 0.93704 1 0.3805 1 0.5751 1 13q loss 43 (65%) 23 0.26075 1 0.00049 0.213 0.00331 1 0.00015 0.0667 0.8504 1 0.19603 1 0.54105 1 0.0059899 1 16p loss 4 (6%) 62 0.68335 1 0.5209 1 0.02305 1 0.03658 1 0.67629 1 0.087519 1 0.2864 1 0.98505 1 16q loss 5 (8%) 61 0.72138 1 0.38743 1 0.0059599 1 0.0066599 1 0.42723 1 0.04972 1 0.072436 1 0.68849 1 17p loss 50 (76%) 16 0.29836 1 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 0.051829 1 8.9999e-05 0.0405 0.049144 1 0.00211 0.88 17q loss 50 (76%) 16 0.29794 1 9.9999e-06 0.00488 9.9999e-06 0.00488 9.9999e-06 0.00488 0.051389 1 9.9999e-05 0.0448 0.049144 1 0.00212 0.882 18p loss 8 (12%) 58 0.67654 1 0.096449 1 0.31478 1 0.21226 1 0.72006 1 0.94923 1 0.66904 1 0.7709 1 18q loss 10 (15%) 56 0.62178 1 0.079909 1 0.44292 1 0.28125 1 0.57228 1 0.86415 1 0.69505 1 0.5121 1 19q loss 3 (5%) 63 0.64412 1 0.76484 1 0.76711 1 0.82319 1 0.516 1 0.86443 1 1 1 0.82077 1 20p loss 4 (6%) 62 0.29963 1 0.80668 1 0.21058 1 0.21537 1 0.45109 1 0.65898 1 0.2864 1 0.55051 1 20q loss 3 (5%) 63 1 1 0.4157 1 0.22613 1 0.058069 1 0.29512 1 0.82558 1 0.056025 1 0.71726 1 21q loss 35 (53%) 31 0.77391 1 0.01054 1 0.2488 1 0.19466 1 1 1 0.12776 1 1 1 0.04248 1 22q loss 8 (12%) 58 0.82931 1 0.13341 1 0.24594 1 0.23365 1 0.89778 1 0.21397 1 0.68742 1 0.35674 1 xq loss 39 (59%) 27 0.59897 1 0.073519 1 0.0068899 1 0.00361 1 0.32652 1 0.00107 0.456 0.77013 1 0.03721 1