Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.447 0.217 0.536 55.0 -9999.0 0.0 55.0 KIRREL -0.093 0.14 -9999.0 0.0 -0.705 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.447 0.217 -9999.0 0.0 -0.537 55.0 55.0 PLCG1 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.029 0.026 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.446 0.263 -9999.0 0.0 -0.523 57.0 57.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.394 0.231 -9999.0 0.0 -0.467 55.0 55.0 FYN -0.427 0.235 -9999.0 0.0 -0.493 57.0 57.0 mol:Ca2+ -0.44 0.259 -9999.0 0.0 -0.521 56.0 56.0 mol:DAG -0.442 0.262 -9999.0 0.0 -0.524 56.0 56.0 NPHS2 -0.301 0.314 -9999.0 0.0 -0.702 25.0 25.0 mol:IP3 -0.442 0.262 -9999.0 0.0 -0.524 56.0 56.0 regulation of endocytosis -0.397 0.237 -9999.0 0.0 -0.466 57.0 57.0 Nephrin/NEPH1/podocin/Cholesterol -0.446 0.258 -9999.0 0.0 -0.521 57.0 57.0 establishment of cell polarity -0.447 0.217 -9999.0 0.0 -0.536 55.0 55.0 Nephrin/NEPH1/podocin/NCK1-2 -0.418 0.252 -9999.0 0.0 -0.491 57.0 57.0 Nephrin/NEPH1/beta Arrestin2 -0.403 0.243 -9999.0 0.0 -0.473 57.0 57.0 NPHS1 -0.555 0.252 -9999.0 0.0 -0.673 54.0 54.0 Nephrin/NEPH1/podocin -0.425 0.248 -9999.0 0.0 -0.496 57.0 57.0 TJP1 0.022 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.022 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.023 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.445 0.264 -9999.0 0.0 -0.527 56.0 56.0 CD2AP 0.021 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.446 0.263 -9999.0 0.0 -0.523 57.0 57.0 GRB2 0.021 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.415 0.236 -9999.0 0.0 -0.49 55.0 55.0 cytoskeleton organization -0.492 0.268 -9999.0 0.0 -0.578 55.0 55.0 Nephrin/NEPH1 -0.328 0.165 -9999.0 0.0 -0.394 55.0 55.0 Nephrin/NEPH1/ZO-1 -0.367 0.189 -9999.0 0.0 -0.445 55.0 55.0