Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.485 0.258 0.617 414.0 -9999.0 0.0 414.0 KIRREL -0.056 0.109 -9999.0 0.0 -0.81 10.0 10.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.486 0.258 -9999.0 0.0 -0.618 414.0 414.0 PLCG1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.038 -9999.0 0.0 -0.863 1.0 1.0 WASL 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.527 0.307 -9999.0 0.0 -0.835 230.0 230.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.408 0.259 -9999.0 0.0 -0.662 230.0 230.0 FYN -0.496 0.298 -9999.0 0.0 -0.793 230.0 230.0 mol:Ca2+ -0.52 0.302 -9999.0 0.0 -0.822 230.0 230.0 mol:DAG -0.524 0.304 -9999.0 0.0 -0.829 230.0 230.0 NPHS2 -0.407 0.381 -9999.0 0.0 -0.804 254.0 254.0 mol:IP3 -0.524 0.304 -9999.0 0.0 -0.829 230.0 230.0 regulation of endocytosis -0.467 0.276 -9999.0 0.0 -0.745 230.0 230.0 Nephrin/NEPH1/podocin/Cholesterol -0.536 0.31 -9999.0 0.0 -0.646 441.0 441.0 establishment of cell polarity -0.485 0.258 -9999.0 0.0 -0.617 414.0 414.0 Nephrin/NEPH1/podocin/NCK1-2 -0.486 0.29 -9999.0 0.0 -0.779 230.0 230.0 Nephrin/NEPH1/beta Arrestin2 -0.475 0.282 -9999.0 0.0 -0.76 230.0 230.0 NPHS1 -0.607 0.324 -9999.0 0.0 -0.781 411.0 411.0 Nephrin/NEPH1/podocin -0.504 0.295 -9999.0 0.0 -0.8 230.0 230.0 TJP1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.033 -9999.0 0.0 -0.743 1.0 1.0 NCK2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.527 0.307 -9999.0 0.0 -0.835 230.0 230.0 CD2AP 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.527 0.307 -9999.0 0.0 -0.835 230.0 230.0 GRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.487 0.299 -9999.0 0.0 -0.784 230.0 230.0 cytoskeleton organization -0.526 0.316 -9999.0 0.0 -0.843 230.0 230.0 Nephrin/NEPH1 -0.363 0.197 -9999.0 0.0 -0.462 414.0 414.0 Nephrin/NEPH1/ZO-1 -0.393 0.214 -9999.0 0.0 -0.502 414.0 414.0