Clinical Features MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q SETD2 44 (11%) 373 1 1 0.50061 1 0.44938 1 9.9999e-06 0.00257 0.66426 1 0.30339 1 0.46999 1 0.078779 1 0.40168 1 0.2362 1 0.54171 1 0.35831 1 BAP1 41 (10%) 376 0.03222 1 0.00043 0.106 0.01615 1 0.00015 0.0372 0.02104 1 0.02384 1 0.00014 0.0349 5.9999e-05 0.0151 3e-05 0.00759 9.9999e-06 0.00257 0.12765 1 0.35092 1 PTEN 18 (4%) 399 0.10576 1 0.0328 1 0.099029 1 0.16889 1 0.11871 1 0.30726 1 3e-05 0.00759 0.00043 0.106 0.00163 0.393 0.1139 1 0.073719 1 1 1 PBRM1 136 (33%) 281 0.14942 1 0.059519 1 0.04147 1 2e-05 0.00508 0.0013 0.315 0.98023 1 0.0065799 1 9.9999e-06 0.00257 0.00369 0.886 0.03088 1 0.00013 0.0325 0.088529 1 KDM5C 26 (6%) 391 NA NA NA NA 0.27504 1 0.088249 1 0.338 1 0.11402 1 0.069079 1 0.10213 1 0.0104 1 0.04136 1 1 1 1 1 VHL 166 (40%) 251 0.11242 1 0.22642 1 0.42264 1 0.74814 1 0.1443 1 0.33297 1 0.0076999 1 0.050539 1 0.1587 1 0.13333 1 0.43674 1 0.73135 1 FAM200A 5 (1%) 412 NA NA NA NA 0.71932 1 NA NA 0.00088999 0.217 0.25359 1 0.14697 1 0.38936 1 0.2069 1 0.4163 1 NA NA NA NA TP53 9 (2%) 408 NA NA NA NA 0.38162 1 0.51466 1 0.44524 1 0.42385 1 0.44598 1 0.17206 1 0.4662 1 0.51688 1 1 1 1 1 NEFH 5 (1%) 412 NA NA NA NA 0.85814 1 0.54196 1 0.9775 1 0.17653 1 0.0098099 1 0.27176 1 0.62701 1 0.82993 1 0.44713 1 0.12048 1 CCDC120 4 (1%) 413 NA NA NA NA 0.10743 1 NA NA 0.4419 1 1 1 0.66779 1 0.48641 1 0.82563 1 1 1 NA NA NA NA MTOR 23 (6%) 394 NA NA NA NA 0.72569 1 0.15355 1 0.00038 0.0939 0.00095999 0.233 0.91933 1 0.75887 1 0.25589 1 0.2463 1 0.87595 1 1 1 GUSB 4 (1%) 413 NA NA NA NA 0.57033 1 NA NA 0.31162 1 0.62676 1 0.17415 1 0.7022 1 0.45459 1 0.87467 1 NA NA NA NA PIK3CA 12 (3%) 405 NA NA NA NA 0.5228 1 0.65325 1 0.79532 1 0.28352 1 0.35607 1 0.44949 1 0.75086 1 0.94465 1 NA NA NA NA PCK1 5 (1%) 412 NA NA NA NA 0.45037 1 0.61988 1 1 1 0.81535 1 0.84968 1 0.45929 1 0.72861 1 0.38576 1 NA NA NA NA ARID1A 12 (3%) 405 NA NA NA NA 0.52074 1 0.25893 1 0.90419 1 1 1 0.32768 1 0.25239 1 0.24676 1 0.0089199 1 0.38196 1 0.19271 1 ATM 11 (3%) 406 NA NA NA NA 0.7282 1 0.47435 1 0.64019 1 1 1 0.29543 1 0.03061 1 0.11528 1 0.091009 1 NA NA NA NA DPCR1 6 (1%) 411 NA NA NA NA 0.20526 1 0.51011 1 0.21574 1 1 1 0.22678 1 0.33471 1 0.87268 1 0.93142 1 NA NA NA NA FGFR3 4 (1%) 413 NA NA NA NA 0.69233 1 0.84113 1 0.95574 1 1 1 0.81548 1 0.29234 1 0.82535 1 0.31571 1 NA NA NA NA PTCH1 7 (2%) 410 NA NA NA NA 1 1 0.054779 1 0.40942 1 0.15722 1 0.8759 1 0.3319 1 0.89563 1 0.60851 1 NA NA NA NA RBMX 4 (1%) 413 NA NA NA NA 0.69383 1 0.61844 1 0.10929 1 0.45672 1 0.40033 1 0.70118 1 0.33591 1 0.12583 1 NA NA NA NA ARAP3 3 (1%) 414 NA NA NA NA 0.60204 1 NA NA 1 1 1 1 0.77473 1 1 1 0.79549 1 0.83911 1 NA NA NA NA GPR172B 4 (1%) 413 NA NA NA NA 1 1 NA NA 0.12043 1 0.79598 1 0.52706 1 1 1 0.61013 1 1 1 NA NA NA NA EGFR 7 (2%) 410 NA NA NA NA 0.69602 1 0.68176 1 0.7378 1 0.49559 1 0.61195 1 0.20974 1 1 1 0.094769 1 NA NA NA NA IL1RAP 4 (1%) 413 NA NA NA NA 0.57108 1 0.61675 1 0.26028 1 0.091809 1 0.81626 1 0.48595 1 0.55757 1 0.63754 1 NA NA NA NA BCL6 5 (1%) 412 NA NA NA NA 0.45013 1 0.61785 1 0.81181 1 0.73206 1 1 1 0.46138 1 0.7266 1 0.48377 1 NA NA NA NA NFAT5 6 (1%) 411 NA NA NA NA 0.36718 1 0.8791 1 0.25426 1 0.53059 1 0.3384 1 0.56701 1 0.28151 1 0.095719 1 NA NA NA NA LARP1 5 (1%) 412 NA NA NA NA 0.44925 1 0.44169 1 0.24087 1 0.52775 1 0.84735 1 1 1 0.6296 1 0.32106 1 NA NA NA NA KIAA1751 6 (1%) 411 NA NA NA NA 0.57939 1 0.64093 1 0.61436 1 0.074709 1 0.32273 1 1 1 0.38618 1 0.32055 1 NA NA NA NA INSRR 4 (1%) 413 NA NA NA NA 0.69499 1 0.12276 1 0.29764 1 0.38756 1 0.39727 1 0.38606 1 0.45464 1 0.78674 1 NA NA NA NA