Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.397 0.231 0.525 391.0 -9999.0 0.0 391.0 KIRREL -0.06 0.087 -9999.0 0.0 -0.627 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.397 0.232 -9999.0 0.0 -0.526 391.0 391.0 PLCG1 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.028 0.032 -9999.0 0.0 -0.707 1.0 1.0 WASL 0.027 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.417 0.28 -9999.0 0.0 -0.542 404.0 404.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.341 0.235 -9999.0 0.0 -0.464 369.0 369.0 FYN -0.4 0.254 0.265 1.0 -0.507 412.0 413.0 mol:Ca2+ -0.408 0.276 -9999.0 0.0 -0.533 404.0 404.0 mol:DAG -0.41 0.279 -9999.0 0.0 -0.536 404.0 404.0 NPHS2 -0.339 0.326 -9999.0 0.0 -0.689 241.0 241.0 mol:IP3 -0.41 0.279 -9999.0 0.0 -0.536 404.0 404.0 regulation of endocytosis -0.373 0.249 -9999.0 0.0 -0.499 369.0 369.0 Nephrin/NEPH1/podocin/Cholesterol -0.422 0.276 -9999.0 0.0 -0.539 416.0 416.0 establishment of cell polarity -0.397 0.231 -9999.0 0.0 -0.525 391.0 391.0 Nephrin/NEPH1/podocin/NCK1-2 -0.38 0.268 -9999.0 0.0 -0.647 216.0 216.0 Nephrin/NEPH1/beta Arrestin2 -0.378 0.254 -9999.0 0.0 -0.633 217.0 217.0 NPHS1 -0.514 0.283 -9999.0 0.0 -0.667 403.0 403.0 Nephrin/NEPH1/podocin -0.399 0.263 -9999.0 0.0 -0.509 416.0 416.0 TJP1 0.03 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.03 -9999.0 0.0 -0.636 1.0 1.0 NCK2 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.413 0.281 -9999.0 0.0 -0.539 404.0 404.0 CD2AP 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.415 0.28 -9999.0 0.0 -0.538 409.0 409.0 GRB2 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.392 0.255 0.276 1.0 -0.512 384.0 385.0 cytoskeleton organization -0.431 0.284 -9999.0 0.0 -0.581 368.0 368.0 Nephrin/NEPH1 -0.289 0.173 -9999.0 0.0 -0.385 391.0 391.0 Nephrin/NEPH1/ZO-1 -0.317 0.199 -9999.0 0.0 -0.428 389.0 389.0