Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.489 0.354 0.72 194.0 -9999.0 0.0 194.0 KIRREL -0.119 0.241 -9999.0 0.0 -0.877 26.0 26.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.491 0.355 -9999.0 0.0 -0.722 194.0 194.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.018 -9999.0 0.0 -0.292 1.0 1.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.527 0.379 -9999.0 0.0 -0.709 215.0 215.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.4 0.311 -9999.0 0.0 -0.546 215.0 215.0 FYN -0.495 0.364 -9999.0 0.0 -0.67 215.0 215.0 mol:Ca2+ -0.519 0.371 -9999.0 0.0 -0.698 215.0 215.0 mol:DAG -0.523 0.375 -9999.0 0.0 -0.703 215.0 215.0 NPHS2 -0.357 0.404 -9999.0 0.0 -0.874 109.0 109.0 mol:IP3 -0.523 0.375 -9999.0 0.0 -0.703 215.0 215.0 regulation of endocytosis -0.463 0.345 -9999.0 0.0 -0.629 215.0 215.0 Nephrin/NEPH1/podocin/Cholesterol -0.533 0.381 -9999.0 0.0 -0.716 215.0 215.0 establishment of cell polarity -0.489 0.354 -9999.0 0.0 -0.72 194.0 194.0 Nephrin/NEPH1/podocin/NCK1-2 -0.49 0.358 -9999.0 0.0 -0.659 215.0 215.0 Nephrin/NEPH1/beta Arrestin2 -0.472 0.355 -9999.0 0.0 -0.642 215.0 215.0 NPHS1 -0.558 0.401 -9999.0 0.0 -0.853 187.0 187.0 Nephrin/NEPH1/podocin -0.503 0.365 -9999.0 0.0 -0.677 215.0 215.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.527 0.379 -9999.0 0.0 -0.709 215.0 215.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.527 0.379 -9999.0 0.0 -0.709 215.0 215.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.606 0.403 -9999.0 0.0 -0.753 234.0 234.0 cytoskeleton organization -0.519 0.392 -9999.0 0.0 -0.709 215.0 215.0 Nephrin/NEPH1 -0.374 0.283 -9999.0 0.0 -0.554 194.0 194.0 Nephrin/NEPH1/ZO-1 -0.409 0.302 -9999.0 0.0 -0.603 194.0 194.0