Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.373 0.283 0.558 192.0 -9999.0 0.0 192.0 KIRREL -0.106 0.19 -9999.0 0.0 -0.686 26.0 26.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.374 0.284 -9999.0 0.0 -0.56 192.0 192.0 PLCG1 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.01 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.012 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.383 0.306 -9999.0 0.0 -0.539 211.0 211.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.319 0.253 -9999.0 0.0 -0.47 187.0 187.0 FYN -0.378 0.268 0.265 1.0 -0.511 211.0 212.0 mol:Ca2+ -0.376 0.3 -9999.0 0.0 -0.537 205.0 205.0 mol:DAG -0.378 0.302 -9999.0 0.0 -0.54 205.0 205.0 NPHS2 -0.291 0.313 -9999.0 0.0 -0.695 107.0 107.0 mol:IP3 -0.378 0.302 -9999.0 0.0 -0.54 205.0 205.0 regulation of endocytosis -0.343 0.271 -9999.0 0.0 -0.486 206.0 206.0 Nephrin/NEPH1/podocin/Cholesterol -0.389 0.299 -9999.0 0.0 -0.541 211.0 211.0 establishment of cell polarity -0.373 0.283 -9999.0 0.0 -0.558 192.0 192.0 Nephrin/NEPH1/podocin/NCK1-2 -0.355 0.292 -9999.0 0.0 -0.506 209.0 209.0 Nephrin/NEPH1/beta Arrestin2 -0.348 0.277 -9999.0 0.0 -0.494 206.0 206.0 NPHS1 -0.45 0.31 -9999.0 0.0 -0.674 187.0 187.0 Nephrin/NEPH1/podocin -0.369 0.287 -9999.0 0.0 -0.514 211.0 211.0 TJP1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.38 0.304 -9999.0 0.0 -0.543 205.0 205.0 CD2AP 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.381 0.304 -9999.0 0.0 -0.544 205.0 205.0 GRB2 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.456 0.298 0.275 1.0 -0.571 228.0 229.0 cytoskeleton organization -0.394 0.305 -9999.0 0.0 -0.586 184.0 184.0 Nephrin/NEPH1 -0.275 0.217 -9999.0 0.0 -0.416 190.0 190.0 Nephrin/NEPH1/ZO-1 -0.304 0.246 -9999.0 0.0 -0.466 190.0 190.0