Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.105 0.247 29.0 -9999.0 0.0 29.0 KIRREL -0.052 0.139 -9999.0 0.0 -0.345 30.0 30.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.105 -9999.0 0.0 -0.247 29.0 29.0 PLCG1 0.019 0.064 -9999.0 0.0 -0.339 5.0 5.0 ARRB2 0.029 0.01 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.028 0.012 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.009 0.094 -9999.0 0.0 -0.188 29.0 29.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.018 0.081 -9999.0 0.0 -0.19 29.0 29.0 FYN -0.024 0.086 0.235 6.0 -0.175 29.0 35.0 mol:Ca2+ -0.0 0.098 -9999.0 0.0 -0.19 33.0 33.0 mol:DAG 0.001 0.099 -9999.0 0.0 -0.19 33.0 33.0 NPHS2 -0.001 0.028 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.001 0.099 -9999.0 0.0 -0.19 33.0 33.0 regulation of endocytosis 0.004 0.084 -9999.0 0.0 -0.163 32.0 32.0 Nephrin/NEPH1/podocin/Cholesterol -0.005 0.082 -9999.0 0.0 -0.179 29.0 29.0 establishment of cell polarity -0.021 0.105 -9999.0 0.0 -0.247 29.0 29.0 Nephrin/NEPH1/podocin/NCK1-2 0.025 0.092 -9999.0 0.0 -0.168 29.0 29.0 Nephrin/NEPH1/beta Arrestin2 0.006 0.086 -9999.0 0.0 -0.165 32.0 32.0 NPHS1 0.0 0.029 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.004 0.084 0.176 1.0 -0.171 32.0 33.0 TJP1 -0.002 0.095 -9999.0 0.0 -0.339 12.0 12.0 NCK1 0.032 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.033 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.002 0.1 -9999.0 0.0 -0.191 33.0 33.0 CD2AP 0.03 0.029 -9999.0 0.0 -0.339 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 0.009 0.09 -9999.0 0.0 -0.182 29.0 29.0 GRB2 0.031 0.008 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.033 0.066 0.155 3.0 -0.164 29.0 32.0 cytoskeleton organization -0.03 0.084 0.203 2.0 -0.204 29.0 31.0 Nephrin/NEPH1 -0.01 0.073 -9999.0 0.0 -0.165 29.0 29.0 Nephrin/NEPH1/ZO-1 -0.02 0.104 -9999.0 0.0 -0.2 40.0 40.0