Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.062 0.148 0.4 79.0 -9999.0 0.0 79.0 KIRREL -0.036 0.162 -9999.0 0.0 -0.593 40.0 40.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.062 0.149 -9999.0 0.0 -0.4 79.0 79.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.045 0.108 -9999.0 0.0 -0.336 41.0 41.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.095 -9999.0 0.0 -0.416 6.0 6.0 FYN -0.023 0.108 -9999.0 0.0 -0.321 41.0 41.0 mol:Ca2+ -0.044 0.107 -9999.0 0.0 -0.333 41.0 41.0 mol:DAG -0.045 0.107 -9999.0 0.0 -0.335 41.0 41.0 NPHS2 -0.006 0.039 -9999.0 0.0 -0.537 2.0 2.0 mol:IP3 -0.045 0.107 -9999.0 0.0 -0.335 41.0 41.0 regulation of endocytosis -0.014 0.102 -9999.0 0.0 -0.298 37.0 37.0 Nephrin/NEPH1/podocin/Cholesterol -0.046 0.111 -9999.0 0.0 -0.298 75.0 75.0 establishment of cell polarity -0.062 0.148 -9999.0 0.0 -0.4 79.0 79.0 Nephrin/NEPH1/podocin/NCK1-2 -0.04 0.098 -9999.0 0.0 -0.532 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.013 0.104 -9999.0 0.0 -0.302 37.0 37.0 NPHS1 -0.034 0.14 -9999.0 0.0 -0.495 43.0 43.0 Nephrin/NEPH1/podocin -0.026 0.108 -9999.0 0.0 -0.323 41.0 41.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.027 -9999.0 0.0 -0.592 1.0 1.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.045 0.108 -9999.0 0.0 -0.336 41.0 41.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.045 0.108 -9999.0 0.0 -0.336 41.0 41.0 GRB2 0.013 0.022 -9999.0 0.0 -0.49 1.0 1.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.042 0.133 -9999.0 0.0 -0.337 54.0 54.0 cytoskeleton organization -0.003 0.111 -9999.0 0.0 -0.456 7.0 7.0 Nephrin/NEPH1 -0.044 0.106 -9999.0 0.0 -0.283 79.0 79.0 Nephrin/NEPH1/ZO-1 -0.048 0.116 -9999.0 0.0 -0.365 40.0 40.0