Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.1 0.227 -9999.0 0.0 -0.45 122.0 122.0 MAP3K8 -0.008 0.102 -9999.0 0.0 -0.512 20.0 20.0 FOS -0.089 0.204 -9999.0 0.0 -0.494 83.0 83.0 PRKCA 0.011 0.028 -9999.0 0.0 -0.597 1.0 1.0 PTPN7 -0.126 0.243 -9999.0 0.0 -0.545 128.0 128.0 HRAS 0.014 0.001 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.063 0.188 -9999.0 0.0 -0.525 72.0 72.0 NRAS 0.014 0.001 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.023 0.017 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.073 0.178 -9999.0 0.0 -0.463 75.0 75.0 MAP2K1 -0.016 0.125 -9999.0 0.0 -0.459 26.0 26.0 ELK1 0.012 0.007 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.052 0.126 -9999.0 0.0 -0.434 42.0 42.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 97.0 97.0 MAPK1 -0.073 0.178 -9999.0 0.0 -0.478 70.0 70.0 RAF1 -0.037 0.1 -9999.0 0.0 -0.425 25.0 25.0 KRAS 0.013 0.022 -9999.0 0.0 -0.49 1.0 1.0