Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.002 0.094 0.318 37.0 -9999.0 0.0 37.0 KIRREL -0.008 0.12 -9999.0 0.0 -0.419 39.0 39.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.002 0.095 -9999.0 0.0 -0.319 37.0 37.0 PLCG1 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.02 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.03 0.08 -9999.0 0.0 -0.237 37.0 37.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.003 0.069 -9999.0 0.0 -0.246 31.0 31.0 FYN -0.009 0.075 0.179 23.0 -0.226 38.0 61.0 mol:Ca2+ 0.027 0.079 -9999.0 0.0 -0.235 38.0 38.0 mol:DAG 0.028 0.08 -9999.0 0.0 -0.236 38.0 38.0 NPHS2 0.001 0.033 -9999.0 0.0 -0.283 2.0 2.0 mol:IP3 0.028 0.08 -9999.0 0.0 -0.236 38.0 38.0 regulation of endocytosis 0.024 0.072 -9999.0 0.0 -0.214 38.0 38.0 Nephrin/NEPH1/podocin/Cholesterol 0.017 0.075 -9999.0 0.0 -0.235 38.0 38.0 establishment of cell polarity -0.002 0.094 -9999.0 0.0 -0.318 37.0 37.0 Nephrin/NEPH1/podocin/NCK1-2 0.04 0.081 -9999.0 0.0 -0.223 37.0 37.0 Nephrin/NEPH1/beta Arrestin2 0.025 0.073 -9999.0 0.0 -0.216 38.0 38.0 NPHS1 -0.001 0.053 -9999.0 0.0 -0.151 39.0 39.0 Nephrin/NEPH1/podocin 0.018 0.073 -9999.0 0.0 -0.227 38.0 38.0 TJP1 0.026 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.025 0.02 -9999.0 0.0 -0.428 1.0 1.0 NCK2 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.028 0.081 -9999.0 0.0 -0.237 38.0 38.0 CD2AP 0.026 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.028 0.08 -9999.0 0.0 -0.237 37.0 37.0 GRB2 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.013 0.086 0.19 25.0 -0.234 45.0 70.0 cytoskeleton organization -0.017 0.082 0.203 12.0 -0.27 31.0 43.0 Nephrin/NEPH1 0.01 0.066 -9999.0 0.0 -0.219 37.0 37.0 Nephrin/NEPH1/ZO-1 0.022 0.081 -9999.0 0.0 -0.252 37.0 37.0