Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.043 0.204 -9999.0 0.0 -0.427 90.0 90.0 MAP3K8 0.015 0.048 -9999.0 0.0 -0.198 18.0 18.0 FOS -0.041 0.18 -9999.0 0.0 -0.437 73.0 73.0 PRKCA 0.02 0.024 -9999.0 0.0 -0.43 1.0 1.0 PTPN7 -0.054 0.152 -9999.0 0.0 -0.288 124.0 124.0 HRAS 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.011 0.098 -9999.0 0.0 -0.224 68.0 68.0 NRAS 0.021 0.01 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.034 0.026 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.032 0.163 -9999.0 0.0 -0.428 67.0 67.0 MAP2K1 0.003 0.104 -9999.0 0.0 -0.438 20.0 20.0 ELK1 0.021 0.017 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.006 0.085 -9999.0 0.0 -0.388 22.0 22.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.004 59.0 59.0 MAPK1 -0.036 0.168 -9999.0 0.0 -0.43 70.0 70.0 RAF1 -0.002 0.086 -9999.0 0.0 -0.414 19.0 19.0 KRAS 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0