Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.045 0.182 -9999.0 0.0 -0.34 6.0 6.0 MAP3K8 0.006 0.089 -9999.0 0.0 -0.276 2.0 2.0 FOS -0.019 0.122 -9999.0 0.0 -0.451 1.0 1.0 PRKCA 0.023 0.021 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.013 0.04 -9999.0 0.0 -0.144 1.0 1.0 HRAS 0.029 0.012 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.004 0.007 -9999.0 0.0 -0.016 7.0 7.0 NRAS 0.026 0.014 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.037 0.03 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.009 0.099 -9999.0 0.0 -0.418 1.0 1.0 MAP2K1 0.014 0.061 -9999.0 0.0 -9999.0 0.0 0.0 ELK1 0.02 0.027 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.006 0.019 -9999.0 0.0 -9999.0 0.0 0.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 8.0 8.0 MAPK1 -0.015 0.115 -9999.0 0.0 -0.418 1.0 1.0 RAF1 0.005 0.021 -9999.0 0.0 -9999.0 0.0 0.0 KRAS 0.029 0.012 -9999.0 0.0 -9999.0 0.0 0.0