Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	62 (31%)	136	0.0068099	0.865	0.47961	1	0.00171	0.226	0.44712	1	0.01941	1	0.00062999	0.0844	0.23369	1	0.01187	1
CTNNB1	51 (26%)	147	0.03824	1	0.00029	0.0394	9.9999e-06	0.00142	9.9999e-06	0.00142	0.04493	1	9.9999e-06	0.00142	0.00047	0.0634	9.9999e-06	0.00142
RB1	15 (8%)	183	0.72687	1	0.00073999	0.0984	0.02475	1	0.14946	1	0.21455	1	0.38886	1	0.21401	1	0.29925	1
AXIN1	9 (5%)	189	0.27678	1	0.47033	1	0.18031	1	0.35779	1	0.0047	0.606	0.45583	1	0.0054799	0.701	0.69445	1
BAP1	10 (5%)	188	0.70529	1	0.00374	0.486	0.00025	0.0342	0.00193	0.253	3e-05	0.00414	0.01069	1	0.03927	1	0.01715	1
TSC2	9 (5%)	189	0.90664	1	0.04056	1	0.13905	1	0.35946	1	0.7675	1	0.56477	1	0.78792	1	0.10973	1
ARID1A	16 (8%)	182	0.83418	1	0.24035	1	0.01691	1	0.32181	1	0.10853	1	0.67224	1	0.01668	1	0.58552	1
IL6ST	7 (4%)	191	0.48888	1	0.26518	1	0.31311	1	0.03437	1	0.43877	1	0.10973	1	0.47738	1	1	1
ALB	18 (9%)	180	0.04092	1	0.01916	1	0.087969	1	0.2969	1	0.82191	1	0.84236	1	0.50364	1	0.25273	1
HNF1A	8 (4%)	190	0.16289	1	0.59767	1	0.1076	1	0.14228	1	0.094379	1	0.15275	1	0.01042	1	0.28365	1
APOB	24 (12%)	174	1	1	1	1	0.092219	1	0.01719	1	0.27824	1	0.071649	1	0.21991	1	0.01978	1
EEF1A1	5 (3%)	193	0.054969	1	0.86468	1	0.12999	1	0.073439	1	0.61163	1	0.26072	1	0.23944	1	0.61697	1
KIF19	10 (5%)	188	0.91761	1	0.13029	1	0.22815	1	0.45728	1	0.38294	1	0.81394	1	0.15534	1	0.10056	1
GNAS	7 (4%)	191	0.8907	1	0.15766	1	0.23662	1	0.75874	1	0.078059	1	0.45199	1	0.55611	1	0.72337	1
F5	4 (2%)	194	0.81885	1	0.20769	1	0.7004	1	1	1	0.098779	1	0.93712	1	NA	NA	NA	NA
PTEN	7 (4%)	191	0.48834	1	0.3261	1	0.86677	1	0.62476	1	0.85818	1	0.2779	1	0.78086	1	0.28517	1
HIST1H1C	5 (3%)	193	0.71976	1	0.86366	1	0.82232	1	0.28018	1	0.8017	1	0.25025	1	0.63884	1	0.02043	1
DLK2	4 (2%)	194	0.81801	1	0.6932	1	0.44202	1	1	1	0.33589	1	0.93611	1	0.18985	1	0.16167	1