Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.027 0.174 0.686 16.0 -9999.0 0.0 16.0 KIRREL -0.05 0.21 0.325 1.0 -0.88 16.0 17.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.027 0.175 -9999.0 0.0 -0.687 16.0 16.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.017 0.139 -9999.0 0.0 -0.53 16.0 16.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.015 0.1 -9999.0 0.0 -0.378 17.0 17.0 FYN -0.025 0.121 -9999.0 0.0 -0.5 16.0 16.0 mol:Ca2+ -0.017 0.137 -9999.0 0.0 -0.525 16.0 16.0 mol:DAG -0.017 0.138 -9999.0 0.0 -0.528 16.0 16.0 NPHS2 0.004 0.047 0.315 5.0 -9999.0 0.0 5.0 mol:IP3 -0.017 0.138 -9999.0 0.0 -0.528 16.0 16.0 regulation of endocytosis -0.015 0.122 -9999.0 0.0 -0.468 16.0 16.0 Nephrin/NEPH1/podocin/Cholesterol -0.018 0.14 -9999.0 0.0 -0.537 16.0 16.0 establishment of cell polarity -0.027 0.174 -9999.0 0.0 -0.686 16.0 16.0 Nephrin/NEPH1/podocin/NCK1-2 -0.016 0.133 -9999.0 0.0 -0.49 17.0 17.0 Nephrin/NEPH1/beta Arrestin2 -0.015 0.125 -9999.0 0.0 -0.475 16.0 16.0 NPHS1 0.019 0.082 0.319 18.0 -9999.0 0.0 18.0 Nephrin/NEPH1/podocin -0.015 0.133 -9999.0 0.0 -0.503 16.0 16.0 TJP1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 -0.003 0.054 -9999.0 0.0 -0.879 1.0 1.0 NCK2 0.001 0.019 0.316 1.0 -9999.0 0.0 1.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.017 0.139 -9999.0 0.0 -0.53 16.0 16.0 CD2AP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.017 0.139 -9999.0 0.0 -0.53 16.0 16.0 GRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.006 0.136 -9999.0 0.0 -0.49 16.0 16.0 cytoskeleton organization -0.021 0.125 -9999.0 0.0 -0.495 16.0 16.0 Nephrin/NEPH1 -0.019 0.134 -9999.0 0.0 -0.522 16.0 16.0 Nephrin/NEPH1/ZO-1 -0.022 0.146 -9999.0 0.0 -0.569 16.0 16.0